Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Bayram, Sinan(9)
- Ayata, Ümit(8)
- Can, Zehra(8)
- Dertli, Enes(8)
- Esmer, Yusuf(8)
- Kaya, Yunus(8)
- Semerci, Vahide(8)
- Akyol Özcan, Kübra(6)
- Kara, Yakup(6)
- Maden, Sedat(6)
- Şahin, Engin(6)
- Bilgin, Yusuf(5)
- Dirican, Ebubekir(5)
- Ertugrul, Mehmet(5)
- Gülden, Bahadır(5)
- Gıdık, Betül(5)
- Imamoglu, Ilyas Kays(5)
- Kaplan, Kadir(5)
- Kaya, Musa(5)
- Koçak, Lokman(5)
- Kutlu, Naciye(5)
- Sönmez Sarı, Ebru(5)
- Ünalan, Ozlem(5)
- İspirli, Hümeyra(5)
- Ates, Fatih(4)
- Bulut, Mehmet(4)
- Bülbül, Ali Savaş(4)
- Ecem Bayram, Nesrin(4)
- Gökçe, H.S.(4)
- Gültekin, Ömer Faruk(4)
- Kadakal, Huriye(4)
- Kahveci, Hakan(4)
- Kamiloğlu, Aybike(4)
- Kaya, Metin(4)
- Kırbaş, Zila Özlem(4)
- Teber, Ahmet(4)
- Uzunçakmak, Sevgi Karabulut(4)
- Uğur, Uçar(4)
- Yilmaz, Sevda(4)
- Öztürk, Mesut(4)
Yayınlar
- MakaleAçık Erişim2023Scopus SJRQ2Contribution of Oxidative Stress, Apoptosis, Endoplasmic Reticulum Stress and Autophagy Pathways to the Ameliorative Effects of Hesperidin in NaF-Induced Testicular Toxicity
Emre Kızıl, Hamit; Gür, Cihan; Ayna, Adnan; Darendelioğlu, Ekrem; Küçükler, Sefa; Sağ, Sevda
The ameliorative effects of hesperidin (HES) on the toxicities created by sodium fluoride (NaF) in the testes tissue of rats were studied via oxidative stress, apoptosis and endoplasmic reticulum (ER) stress pathways. The animals were divided into five distinct groups (7 rats in each group). Group 1 was control group, group 2 received NaF-only (600 ppm), group 3 received HES-only (200 mg/kg bw); group 4 received NaF (600 ppm)+HES (100 mg/kg bw) and group 5 received NaF (600 ppm)+HES (200 mg/kg bw) for 14 days. NaF-induced testes tissue damage by reducing activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) and levels of glutathione (GSH), and increasing lipid peroxidation levels. NaF treatment significantly downregulated the mRNA levels of SOD1, CAT and GPx. NaF supplementation caused apoptosis in the testes by upregulating p53, NFkB, caspase-3, caspase-6, caspase-9, and Bax and downregulating Bcl-2. Furthermore, NaF caused ER stress via increasing mRNA transcript levels of PERK, IRE1, ATF-6 and GRP78. NaF treatment led to autophagy via upregulation of Beclin1, LC3A, LC3B and AKT2. In testes tissue, however, co-treatment with HES at doses of 100 and 200 mg/kg significantly reduced oxidative stress, apoptosis, autophagy and ER stress. Overall, the findings of this study suggest that HES may help to reduce testes damage caused by NaF toxicity.
AtıfScopus49WoS46OpenAlex47
İncele - MakaleAçık Erişim2023Scopus SJRQ1Palynological, chemical, antimicrobial, and enzyme inhibition properties of Cannabis sativa L. propolis
Özkök, Aslı; Karlıdağ, Semiramis; Keskin, Merve; Bayram, Sinan; Keskin, Şaban; Karabulut, Ercan; Çiçek, Fevzi; Yılmaz, İsmet
In this study, both chemical characterization and biological activities of propolis samples obtained from Cannabis sativa L. (cannabis, hemp, marijuana) isolated colonies (research group) and obtained from colonies at a distance where the bee cannot fly to the isolation area (control group) were determined. Palynological analyses of propolis samples obtained from the research and control group colonies were made and the botanical origin of the cannabis plant and other plants in the research area and the plants in the control group were determined. Bioactive component analysis of propolis extracts was determined by the GC–MS technique. The inhibition effect of propolis samples on some enzymes of medical importance and their antimicrobial effects against many pathogenic microorganisms were also investigated. Palynological analyses showed that honey bees prefer cannabis plants (11.11%) when collecting propolis, and the dry matter percentage (94.6 ± 1.8%), balsam (46.2 ± 5.2%), and wax content (4.8 ± 0.5%), total phenolic (26.44 ± 1.08 mg GAE/mL) and total flavonoid (2.03 ± 0.11 mg QE/mL) content and antioxidant capacity (88.16 ± 2.27 μM FeSO4·7H2O/mL−1) of the research group propolis samples containing hemp were found to be higher than the control group. Also, it was determined that the research group propolis sample contains cannabinoid derivatives (cannabidivarinic acid, 0.29%; delta (1)-tetrahydrocannabinolic acid, 0.59%; cannabidiolic acid, 0.48%), which are active compounds of the cannabis plant. Also, a high inhibition effect was detected on some enzymes of medical importance in propolis samples obtained from cannabis group colonies. In addition, the research group propolis samples also showed a high antimicrobial effect against many pathogenic microorganisms.
AtıfScopus5WoS5OpenAlex4İncele - MakaleAçık Erişim2023Scopus SJRQ2Thermal, rheological, and mechanical characterization of compression and injection molded ultra-high molecular weight polyethylene, high density polyethylene, and their blends
Yang, Huaguang; Yilmaz, Galip; Jiang, Jing; Langstraat, Thomas; Chu, Raymond; van Es, Martin; Garg, Priya; Turng, Lih-Sheng
Tensile and impact test samples of ultra-high molecular weight polyethylene (UHMWPE), high-density polyethylene (HDPE), and their blends at various UHMWPE/HDPE weight ratios were prepared via compression molding and injection molding for thermal, rheological, and mechanical characterization. A twin-screw extruder with either a tapered die with air-cooling or a regular die was used to compound and extrude the materials prior to pelletization and molding. To the best of our knowledge, there has been no publication on pelletizing neat UHMWPE using a regular extruder. The differential scanning calorimetry analysis suggested the occurrence of re-crystallization and co-crystallization for all the blends. The rheology test confirmed that all the blends exhibited a solid-like behavior and the degree of compatibility increased with increasing HDPE content in the blends. A strong synergistic effect was observed the blends possessed a higher tensile and impact strength than their neat UHMWPE and HDPE counterparts. The compression molded (95/5) UHMWPE/HDPE samples extruded using the tapered die yielded the highest tensile strength (50.1 MPa), which was about 40% higher than that of the neat UHMWPE samples. The best composition of these blends for compression and injection molded parts is 10% HD and 50% HD, respectively.
AtıfScopus13WoS13OpenAlex14İncele - MakaleYalnız künye2023EXAMINING COGNITIVE STRUCTURES OF SECONDARY SCHOOL STUDENTS REGARDING CONCEPTS RELATED TO MULTICULTURAL EDUCATION
Yılmaz, Sevda
The aim of this study was to investigate the cognitive structures of secondary school students regarding concepts related to multicultural education. The study was conducted through a survey design. The study group consisted of 189 eighth-grade students studying in secondary school. Out of the 189 participants, 97 were female and 92 were male. The criterion sampling method, one of the purposeful sampling methods, was used in the selection of the study group. Word Association Test was used as a data collection tool for the research. According to results of the study, it was determined that secondary school students associated the most words with the concept of culture and the fewest words with the concept of respect. In addition, it has been determined that there is a misconception in the cognitive structures of the students regarding the perceptions of justice and equality. The research results has also shown that the students only weakly correlated concepts related to multicultural education.
- MakaleYalnız künye2023Scopus SJRQ3Modified distance optimization method for the asymmetric bioreduction conditions of phenyl(thiophen-2-yl)methanone by Weissella paramesenteroides N7
Özdemir, Akın; Şahin, Engin
Chirality plays a significant part in life since it is closely linked to carrying out the many metabolic processes that make up a living being. Chiral secondary alcohols such as diaryl-, aryl heteroaryl-, and diheteroaryl are employed in pharmaceuticals as drug intermediates. Although biocatalytic asymmetric reduction of prochiral ketones containing aromatic and heteroaromatic groups is widely known, biocatalytic reduction of heteroaromatic prochiral ketones containing sulfur heteroatoms is rarely known. Very few studies exist in the literature, including the biocatalytic reduction of phenyl(thiophen-2-yl)methanone (1). Moreover, the biocatalytic reduction of 1 with a mathematical modelling and optimization technique is unknown until now. In this study, Weissella paramesenteroides N7 biocatalyst for the asymmetric bioreduction of 1 using a novel modified distance optimization method. Optimization conditions were found as pH = 6.46, temperature = 26 °C, incubation period = 71 h, agitation speed = 200 rpm by the modified distance optimization method, and it was determined that the conversion and enantiomeric excess (ee) under these conditions could be 98.7% and 98%, respectively. Under these proposed optimization conditions, (S)-phenyl(thiophen-2-yl)methanol ((S)-2) was obtained with >99% ee, >99% conversion, and 97% yield. In addition, 11.29 g of 1 was completely converted into (S)-2 (11.07 g, 97% isolated yield) under optimized conditions. This is the first report about the fabrication of enantiopure (S)-2 in high gram scale using a biocatalyst and a novel modified distance optimization technique. In this study, the successful applicability of the new modified distance optimization method in biocatalytic asymmetric reduction reactions has been successfully demonstrated.
AtıfScopus3WoS3OpenAlex5İncele - MakaleAçık Erişim2023Scopus SJRQ3Numerical investigation of the Mode I/Mode II fracture behavior of the hybrid composite joints with a hybrid bondline
Erbayrak, Engin
In this study, the fracture behavior of fracture characterization bonded joints consisting of hybrid composite adherends and hybrid bondlines under Mode I and Mode II loadings were investigated numerically. Numerical analysis was performed using LS-DYNA. Hybrid composite laminates (HCGFRE) obtained by sequencing plain woven glass fiber reinforced epoxy (GFRE) and plain woven carbon fiber reinforced laminates (CFRE) as adherends. Araldite AV138M and Araldite 2015 epoxy adhesives were also used to create the hybrid bondline. Mode I and mode II fracture behaviors were determined by numerical modeling of the Double Cantilever Beam (DCB) and End Notched Flexural (ENF) tests, respectively. In the numerical model, firstly, the fracture parameters of the relevant adhesives were found in the literature, and verification was made utilizing the numerical model. Then, the fracture behavior in both two modes was examined by forming a hybrid bondline. In the literature, there are restricted studies examining the fracture behavior of fracture characterization bonded joints with hybrid bondlines. Additionally, it is not encountered any study determining the both mode I and mode II fracture behavior of composite fracture characterization bonded joints with hybrid bondlines. Therefore, it is thought that this study will gain significant novelties to the existing literature.
AtıfScopus1OpenAlex2İncele - MakaleAçık Erişim2023Scopus SJRQ1An extensive survey on radiation protection features of novel hafnium iron-borophosphate glasses: Experimental and theoretical study
Şakar, Erdem; Alım, Bünyamin; Ertap, Hüseyin; Karabulut, Mevlut
This study aimed to determine the radiation (photon and particle) attenuation abilities of Hf added iron-borophosphate glasses considered as a candidate host matrix for Pu containing nuclear waste. Experimental absorption parameters were measured using 133Ba radionuclide for photon radiation, and the same parameters were theoretically calculated using Phy-X/PSD. The obtained data were evaluated comparatively for all glasses depending on the Hf and B contents. It has been determined that all of the glasses examined have photon absorption ability at a level that can be a shielding material for nuclear applications. In addition, the interaction cross-sections with particle radiations were computed using SRIM and ESTAR software. When the data obtained are evaluated thoroughly, it can be said that investigated glasses can be used as shielding in areas that require protection from both photon and particle radiation, in addition to being a candidate material for the vitrification of nuclear wastes containing Pu.
AtıfScopus5WoS6OpenAlex8İncele - Derleme MakaleAçık Erişim2023Scopus SJRQ2A Meta-Analytic Review of the Effect of Socioeconomic Status on Academic Performance
Selvitopu, Abdullah; Kaya, Metin
The two main purposes of the current meta-analysis were (a) to determine the relation between socioeconomic status (SES) of students and academic performance (AP) (b) and evaluate the effect of several potential moderating factors in this relation. Data covered the publications between 2010 and 2019, and the dataset consisted of 48 independent studies that included 62 different samples, and the total sample was 386.601. Findings revealed that the relation between SES and academic performance represented a moderate positive correlation. All moderators, type of SES measure, academic performance scale, location, grade level, subjects of academic performance, and year, produced significant effects, respectively. These findings were discussed for every category of moderators with the related literature.
AtıfScopus65WoS54OpenAlex81İncele - MakaleAçık Erişim2023Scopus SJRQ1Optimizing the seismic resilience performance of steel truss bridges by maximum energy dissipation via friction dampers
Artar, Musa; Carbas, Serdar
The primary aim of this study is to propose an innovative design methodology for optimizing the seismic resilience performance of steel truss bridges by dissipating the maximum input seismic energy. Maximum seismic energy dissipation is carried out by means of Pall friction dampers (PFDs), popularly categorized among passive energy-damping devices. PFDs distribute input seismic energy with a slip motion along with friction during an earthquake. For that, it is important to determine the optimal slip load value for the PFDs to start working before the structural elements reach the yield point. To determine the optimal slip load values of the PFDs under earthquake effects, the maximum seismic energy distribution is assured by nature-inspired Squirrel Search (SS) and Water Strider (WS) metaheuristic algorithms for steel truss bridges equipped with PFDs. Finally, steel truss bridges on which PFDs with optimal slip load values have been implemented are optimally designed to achieve the minimal structural weight while satisfying ASD-AISC Code of Practice requirements. In order to demonstrate the validity of the proposed design methodology, two design examples of 113-member and 465-member steel truss bridges steel are presented. The optimal slip loads attained with the SS and WS algorithms by conducting the proposed design methodology are 2.45% and 3.75% of the structural weight for the first design example and 2.64% and 2.63% of the structural weight for the second design example, respectively, which are much lower than those considered in practical applications. Moreover, the numerical results show that by 93.5% and 99.48% maximum distribution rates of input seismic energy are accomplished in the bridges. The results indicate that the proposed design methodology exhibit superior performance in optimizing the seismic resilience performance of steel truss bridges by maximum energy dissipation via friction dampers.
AtıfScopus8WoS4OpenAlex5İncele - MakaleAçık Erişim2023Scopus SJRQ1Prevalence and predictors of psychological assistance services for older individuals in Turkish society
Coşkun, Hüseyin; Yildiz, Ibrahim; Alkan, Ömer
Background/aim: Due to the high contribution of psychological problems to the decline in the comfortable lifestyle of the older individuals, determining the factors that affect individuals' receiving psychological services and searching for solutions based on these factors is one of the primary concerns of national and international decision-makers. This study aimed to identify the factors that affect older individuals' access to psychological assistance services in Turkey. Methods: In this study, the Turkish Health Research micro dataset, which was conducted by the Turkish Statistical Institute (TURKSTAT) in 2016 and 2019, was employed. In this dataset, the data of 7,252 older individuals were analyzed. Using binary logistic analysis, the factors that are effective for obtaining psychological assistance for the older individuals were identified. Results: According to the results of the analysis, factors such as gender, education, general health status, disease status, payment of health expenditures, and body mass index affected older individuals who received psychological assistance. Conclusion: In recent years, there has been a rise in the availability of psychological assistance services for the older individuals. By identifying factors that increase the likelihood of receiving psychological assistance services, this study is expected to contribute to the creation and regulation of psychological assistance services to prevent possible psychological problems that may occur in old age, minimize the problems experienced by individuals, and promote a more comfortable lifestyle.
AtıfScopus23WoS23OpenAlex24İncele - MakaleYalnız künye2023Scopus SJRQ2The effect of guided imagery applied on geriatric orthopaedic patients on preoperative anxiety and comfort
Gunes, Huseyin; Saritas, Serdar; Ozdemir, Ahmet; Bulbul, Ali Savas
Background: This study was designed to examine the effect of guided imagery applied to geriatric orthopaedic patients on preoperative anxiety and comfort. Methods: This study was conducted as a randomized controlled trial. The population of the study consisted of geriatric patients treated in the orthopaedics and traumatology clinic of a university hospital. The sample consisted of 80 patients, including the experimental group (n = 40) and the control group (n = 40). Personal Descriptive Form, The State–Trait Anxiety Inventory (STAI) and General Comfort Scale were used as data collection tools. Results: After the guided imagery application, it was determined that the anxiety of the experimental group decreased statistically significantly, and their comfort improved (P < 0.05). Conclusion: After the imagery, it was determined that the patients in the experimental group had a decrease in their anxiety level and an improvement in their comfort. Since it is a low-cost and easily accessible method, applying imagery in the preoperative period is recommended.
AtıfScopus5WoS5OpenAlex5İncele - MakaleAçık Erişim2023Scopus SJRQ2Efficient bio-catalytic production of enentiopure (S)-(4-chlorophenyl)(phenyl)methanol as a drug precursor by using a novel rotatable composite design-based optimization strategy
Tozlu, Nesrullah; Bülbül, Ali Savaş; Özdemir, Akın; Şahin, Engin
Asymmetric bioreductions catalyzed by biocatalysts have demonstrated great promise in manufacturing chiral alcohols. On the other hand, the synthesis of (S)-(4-chlorophenyl)(phenyl)methanol ((S)-2), precursors of L-cloprastine and carbinoxamine, still presents considerable challenges due to the inadequate substrate quantity and production process. In this work, a novel rotatable composite design-based optimization technique was used with the Lactobacillus paracasei BD101 biocatalyst for the asymmetric reduction of (4-chlorophenyl)(phenyl)methanone (1). Optimization conditions of the reaction were determined by the proposed optimization strategy as: pH=5.85, temperature=37 °C, incubation time=71 h, and agitation speed=120 rpm. The reaction conversion and the product of enantiomeric excess (ee) were also predicted to be 97% and 99%, respectively. In the experimental study performed under the determined optimized conditions, (S)-2 was obtained with >99% ee, >99% conversion, and 97% yield. In addition, 1 with the amount of 15.166 g was completely converted to (S)-2 (14.85 g, 97% isolated yield) on a high-gram scale. Notice that the manufacture of (S)-2 on a gram scale utilizing a biocatalyst and an optimization technique is demonstrated in this work for the first time. Finally, an economical, effective, and environmentally friendly biocatalytic process for the biocatalytic synthesis of (S)-2, which have antitussive and antiemetic properties and relax the bronchial muscle, has been demonstrated by the novel rotatable composite design-based optimization method.
AtıfScopus3WoS3OpenAlex2İncele - MakaleAçık Erişim2023Scopus SJRQ2Extended 2-D Magnetic Field Modeling of Linear Motor to Investigate the Magnetic Force Parameters of High-Speed Superconducting Maglev
Ozturk, Ufuk Kemal; Abdioglu, Murat; Ozkat, Erkan Caner; Mollahasanoglu, Hakki
A 2-D numerical finite-element model of a linear synchronous motor (LSM) is extended based on the magnetic field and moving mesh properties to investigate the magnetic flux and magnetic force characteristics of the high-speed electromagnetic levitation Maglev system, by using high-temperature superconductor (HTS) coils rather than lower current-carrying copper coils on the onboard unit and permanent magnets (PMs) on the ground. In this 2-D LSM model, the transient time-dependent solver is used to obtain the magnetic flux densities. Both the propulsion and levitation forces increased with increasing supercurrent Jc0 values indicating the advantage of using the superconducting windings in PM-LSM of Maglev vehicles as compared with the copper wires. It was also determined that, although the propulsion force is obtained on a comparable level with the studies in the literature, the lower levitation force issue than the electrodynamic suspension (EDS), despite the better propulsion to levitation force ratio, can be overcome by using the high flux trapping capacity bulk HTSs on the onboard unit together with the superconducting coils. The determined higher propulsion force in this PM-LSM Maglev model indicates that the Maglev vehicle can reach higher velocities in a short distance, and thus, this vehicle can be effectively used in short-distance travels in addition to the long-distance transportation. On the other hand, since the EDS system to be accelerated in a certain time interval via conventional wheels to achieve sufficient levitation, PM-LSM system can be integrated into the EDS Maglev system to ensure higher acceleration in a short time interval in addition to the higher levitation and propulsion force performances.
AtıfScopus10WoS10OpenAlex8İncele - MakaleAçık Erişim2023Scopus SJRQ2Utilization of Response Surface Methodology in Optimization of Proline Extraction from Castanea sativa Honey
Ecem Bayram, Nesrin; Kutlu, Naciye; Can Gercek, Yusuf
Proline constitutes approximately 85 % of the amino acid composition of honey. Therefore, the quantitative determination of this amino acid in honey samples is used by many national/international authorities to evaluate the quality of honey types. In this study, it was aimed to achieve maximum proline amino acid extraction from honey samples whose botanical origins were confirmed by melissopalynological analysis. For this reason, based on three different spectrophotometric methods used in the literature for proline analysis, proline extraction was optimized with the Response Surface Method (RSM) and Box-Behnken experimental design. Three independent variables were determined as treatment time (2, 6, and 10 min), treatment temperature (22, 46, and 70 °C), and cooling time (5, 25, and 45 min). As a result of the optimization, it was seen that only significantly effective independent variable on the proline content of honey was the processing temperature. The optimum conditions obtained as a result of the RSM were found to be 2 min for the treatment time, 70 °C for the treatment temperature and 45 min for the cooling time. The composite desirability of the optimum conditions (R2) was found to be 1.00. It was determined that the method proposed by International Honey Commission (IHC) is efficient for proline analysis, but it provides more proline extraction by reducing of time from 10 min to 2 min in hold time in boiling water bath only during the extraction step. As a result, the conditions to be used in order to achieve maximum proline extraction with different spectrophotometric methods were determined and optimum values were determined. In addition, since the botanical origin of honey samples significantly affects the proline content of honey, it can be suggested that this study be optimized for different monofloral honey samples as well.
AtıfScopus7WoS4OpenAlex8İncele - MakaleAçık Erişim2023Validity and Reliability Study of Listening Attitude Scale for Prospective Teachers
Kaplan, Kadir
The aim of this study is to develop a measurement tool to measure the listening/watching attitudes of pre-service teachers. 387 pre-service teachers were administered the scale, and its validity and reliability studies were conducted by exploratory factor analysis, internal consistency measurement, and confirmatory factor analysis. EFA revealed that the scale has four dimensions. To determine the reliability of the scale, the Cronbach Alpha internal consistency coefficient was calculated at 0.928. In the principal component analysis, Kaiser-Meyer-Olkin (KMO) coefficient was found to be 0.937. In addition, the Barlett Sphericity test was significant (χ2 = 4607.552; p<0.05). Varimax rotation resulted in factor loadings ranging between 0.37 and 0.91. In CFA, the standardized regression coefficients averaged around 0.700 and the items in each dimension had a significant predictive power. As a result of the analysis, a valid and reliable scale was obtained.
AtıfScopus1İncele - MakaleAçık Erişim2023Scopus SJRQ3Optimization of asymmetric bioreduction conditions of 1-(thiophen-2-yl)ethanone by Weissella cibaria N9 using a desirability function-embedded face-centered optimization model
Bolubaid, Mohammed; Özdemir, Akın; Dertli, Enes; Alamoudi, Mohammed; Taylan, Osman; Karaboğa, Derviş; Yılmaz, Mustafa Tahsin; Şahin, Engin
Prochiral ketones can be effectively bio-reduced to chiral secondary alcohols by whole-cell biocatalysts, which are possible useful precursors to synthesize physiologically active chemicals and natural products. When whole-cell biocatalysts strains are used, bioreduction process can be influenced by various cultural factors, and it is vital to optimize these factors that affect selectivity, conversion rate, and yield. In this study, Weissella cibaria N9 was used as whole-cell biocatalyst for bioreduction of 1-(thiophen-2-yl)ethanone, and cultural design factors were optimized using a desirability function-embedded face-centered optimization model. For this, effects of pH (4.5–5.5–6.5, x 1), (2) temperature (25–30–35 °C, x 2), (3) incubation period (24–48–72 h, x 3), and (4) agitation speed (100–150–200 rpm, x 4) on two response variables; (1) ee (%) and (2) cr (%) were tested. Next, desirability function-embedded face-centered optimization model revealed that a pH of 6.43, a temperature of 26.04 °C, an incubation period of 52.41 h, and an agitation speed of 150 rpm were the optimum levels and the estimated ee and cr responses were 99.31% and 98.16%, respectively. Importantly, the actual experimental ee and cr responses were similar to the estimated values indicating the capability of the offered desirability function-embedded face-centered optimization model when using the optimum cultural conditions.
AtıfScopus1WoS1OpenAlex3İncele - MakaleYayıncıda açık erişim2023Scopus SJRQ1Examining the attitudes of sexually abused and non-abused individuals towards marriage in terms of ambivalent sexism
Çelik, Eyüp; Dombak, Kübra; Kaya, Mehmet; Sahranç, Ümit; Makas, Samet; Koçak, Lokman; Takunyacı, Mithat; Bekir, Seyhan
The research aims to examine the attitudes of individuals who are victims of abuse and those who are not towards marriage in terms of ambivalent sexism. The research study group consists of 718 individuals between the ages of 18–48. Research data were collected with the Inonu Marriage Attitude Scale and Ambivalent Sexism Inventory. As a result of the correlation analysis, it was concluded that the marriage attitude was positively and significantly correlated with hostile and protective sexism. However, since the relationship between hostile sexism and attitudes towards marriage is lower than that of protective sexism, hostile sexism was not included in the model as a control variable. In the covariance analysis, it is seen that protective sexism and sexual abuse predict the attitude towards marriage at a statistically significant level. In addition, when the effect of sexual abuse on the attitude towards marriage was examined by controlling the protective sexism variable, it was found that it was statistically significant without the effect of sexism. According to the findings, it was determined that individuals who were not victims of sexual abuse had higher attitudes towards marriage than those who were victims. Copyright:
AtıfScopus4WoS5OpenAlex4İncele - MakaleAçık Erişim2023Scopus SJRQ1Structural characterization of potato starch modified by a 4,6-α-glucanotransferase B from Lactobacillus reuteri E81
Hassanein, Wael S.; İspirli, Hümeyra; Dertli, Enes; Yilmaz, Mustafa Tahsin
The recent reports have revealed that increase in amount of α-1,6 linkages by modification of potato starch with enzyme (glycosyltransferases) treatment gains slowly digestible properties to the starch; however, the formation of new α-1,6-glycosidic linkages diminish the thermal resistance of the starch granules. In this study, a putative GtfB-E81, (a 4,6-α-glucanotransferase-4,6-αGT) from L. reuteri E81 was firstly used to produce a short length of α-1,6 linkages. NMR results revealed that external short chains mostly comprised of 1–6 glucosyl units were newly produced in potato starch, and the α-1,6 linkage ratio was significantly increased from 2.9 % to 36.8 %, suggesting that this novel GtfB-E81 might have potentially an efficient transferase activity. In our study, native and GtfB-E81 modified starches showed fundamental similarities with respect to their molecular properties and treatment of native potato starch with GtfB-E81 did not remarkably change thermal stability of the potato starch, which seems to be very prominent for the food industry given the significantly decreased thermal stability results obtained for the enzyme modified starches reported in the literature. Therefore, the results of this study should open up emerging perspectives for regulating slowly digestible characteristics of potato starch in future studies without a significant change in the molecular, thermal, and crystallographic properties.
AtıfScopus14WoS14OpenAlex18İncele - MakaleYalnız künye2023Scopus SJRQ1Utilisation of an active branching sucrase from Lactobacillus kunkeei AP-37 to produce techno-functional poly-oligosaccharides
İspirli, Hümeyra; Korkmaz, Kader; Arioglu-Tuncil, Seda; Bozkurt, Fatih; Sağdıç, Osman; Tunçil, Yunus Emre; Narbad, Arjan; Dertli, Enes
Glucansucrase AP-37 was extracted from the culture supernatant of Lactobacillus kunkeei AP-37 and characteristics of the glucan produced by the active glucansucrase in terms of structural and functional roles were determined in this study. A molecular weight around 300 kDa was observed for glucansucrase AP-37 and its acceptor reactions with maltose, melibiose and mannose were also conducted to unveil the prebiotic potential of the poly-oligosaccharides formed via these reactions. The core structure of glucan AP-37 was determined by 1H and 13C NMR and GC/MS analysis which revealed that glucan AP-37 was a highly branched dextran composing of high levels of (1 → 3)-linked α-D-glucose units with low levels of (1 → 2)-linked α-D-glucose units. The structural features of the glucan formed, demonstrated that glucansucrase AP-37 was an α-(1 → 3) branching sucrase. Dextran AP-37 was further characterised by FTIR analysis and XRD analysis demonstrated its amorphous nature. A fibrous compact morphology was observed for dextran AP-37 with SEM analysis whereas TGA and DSC analysis revealed its high stability as no degradation was observed up to 312 °C. Finally, the prebiotic potential of the dextran AP-37 and the gluco-oligosaccharides produced with the acceptor reaction of α-(1 → 3) branching sucrase AP-37 were determined and promising results were found for the gluco-oligosaccharides to act as prebiotics.
AtıfScopus13WoS12OpenAlex13İncele - MakaleYalnız künye2023Scopus SJRQ1Biological control of green mould on mandarin fruit through the combined use of antagonistic yeasts
Öztekin, Sebahat; Karbancioglu-Guler, Funda
Penicillium digitatum is the primary cause of green mould in mandarins during the postharvest period, mainly controlled through synthetic fungicides. This study evaluated the biocontrol of green mould on mandarin fruit with three antagonistic yeasts (Hanseniaspora uvarum, Meyerozyma guilliermondii, and Metschnikowia aff. pulcherrima P01A016), alone or in combination, by elucidating their possible mechanisms of action. All yeast cultures alone (73.85 % − 80.64 %) and their combinations (78.40 % − 83.18 %) reduced the mycelial growth of green mold in vitro. M. aff. pulcherrima reduced the disease incidence and lesion diameters by 75.5 % and 91.3 %, respectively, demonstrating the highest biocontrolling activity alone. Meyerozyma guilliermondii showed the highest biofilm formation (OD 0.93 ± 0.01) and antifungal activity (71.13 %) through volatile organic compounds (VOCs), while H. uvarum displayed cell-wall degrading β-1,3 glucanase activity together with mycocinogenic and VOCs activity. All tested yeasts showed chitinase, protease, and leucine arylamidase activity. Among dual combinations, M. guilliermondii and M. aff. pulcherrima (M-1) were the most compatible, while M. aff. pulcherrima and H. uvarum (M-3) had the least compatibility. The combined application of these three yeasts resulted in synergistic co-operation, demonstrating the highest biocontrolling efficacy in vitro and in vivo. Integrating multiple mechanisms of action in yeasts could create a hurdle approach for inhibiting green mould in citrus as a green alternative to synthetic fungicides. Thus, our study demonstrated that combining biocontrol yeasts can result in beneficial consortia for the eco-friendly and sustainable management of P.digitatum-caused postharvest diseases of mandarins in both the wounded and intact mandarin fruits.
AtıfScopus42WoS39OpenAlex40İncele