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MakaleAçık Erişim2026Scopus SJRQ1/r/bayburt/10814
Effect of Perioperative Supplementation with Arginine and Omega-3 on Postoperative Complications in Patients Undergoing Gastrointestinal Cancer Surgery: A Pilot Open-Label Randomized Controlled Trial
Sakhri, Saida; Othman, Rym Ben; Jerbi, Chaima; Ceylan, Halil Ibrahim; Naija, Lamia; Zemni, Ines; Jamoussi, Henda; Dhiab, Tarek Ben; Ceylan, Nagihan Burcak; Stefanica, Valentina
Background: Perioperative immunonutrition, including arginine and omega-3 fatty acids, has been proposed to support postoperative recovery by modulating immune function. Aim: To evaluate the effects of perioperative arginine and omega-3 supplementation on postoperative infectious complications, mortality, hospital length of stay, intensive care unit duration, and inflammatory markers in patients undergoing gastrointestinal cancer surgery. Methods: In this Pilot Open-Label randomized trial, 35 adult patients scheduled for elective gastrointestinal cancer surgery at Salah Azaiez Institute were randomly assigned to receive either perioperative immunonutrition (n = 18; three daily capsules of omega-3 and one sachet of Arginine+ for 7 days preoperatively and 7 days postoperatively) or standard care (n = 17). Primary endpoints were postoperative infectious complications and 1-month mortality. Secondary endpoints included hospital length of stay, ICU duration, and postoperative biochemical markers. Results: No statistically significant differences were observed between groups in 1-month mortality (p = 0.324), hospital length of stay (median 7 vs. 7 days, p = 0.392), or ICU duration (median 5 vs. 6 days, p = 0.601). Urinary tract infection (5.9% vs. 11.1%, p = 0.939) and wound infection rates (5.9% vs. 11.1%, p = 0.581) were comparable. Importantly, postoperative C-reactive protein and other inflammatory markers did not differ significantly between groups (CRP: 165 vs. 175 mg/L; intergroup p = 0.798). Conclusions: In this trial, perioperative immunonutrition with arginine and omega-3 fatty acids did not improve postoperative clinical outcomes or inflammatory markers in patients undergoing gastrointestinal cancer surgery. At the administered dose and within a small, heterogeneous cohort, immunonutrition did not provide additional benefit beyond standard care. Larger, adequately powered multicenter trials with optimized dosing are required to clarify its role in gastrointestinal oncology.
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MakaleAçık Erişim2026Scopus SJRQ2/r/bayburt/10789
Comprehensive characterization of 26 Turkish asteraceae species: Insights from FTIR, phytochemical composition, and elemental analysis via ICP-MS
Civas, Ayse; Karakas, Seydanur; Bayrak, Burak; Akyüz, Beyzanur; Keçeci, Emire Bengisu; Özerd, Elif Beyza; Sönmez, Hatice Rumeysa; Asgarli, Tugay; Disli, Fatma Taeb; Yuca, Hafize
This study provides a comprehensive phytochemical, elemental, and spectroscopic characterization of 26 species belonging to the Asteraceae family, several of which are endemic to T & uuml;rkiye and traditionally used in folk medicine. Qualitative screening revealed the widespread presence of flavonoids, saponins, tannins, and carbohydrates, while alkaloids and anthracene heterosides were entirely absent in all taxa. Among the species analyzed, Cichorium intybus, Cyanus depressus, Achillea arabica, and Cirsium davisianum exhibited the richest phytochemical diversity, suggesting strong biological potential. Quantitative evaluation showed that Klasea serratuloides possessed the highest total phenolic content (99.49 mu g GAE/mg extract), followed by Artemisia scoparia and Inula sarana, indicating notable antioxidant potential. Elemental analysis by ICP-MS demonstrated significant interspecies variation, with Centaurea armena, Centaurea arvensis, and Cichorium intybus containing elevated levels of essential macro- and trace elements such as K, Mg, Ca, Zn, and Se, whereas Helichrysum plicatum and Scorzonera ulrichii showed high Co and Se contents. Conversely, trace levels of potentially toxic elements (e.g., Al, U) were detected in some taxa, emphasizing the need for careful evaluation of their pharmacological use. FTIR analysis confirmed the presence of functional groups characteristic of phenolics, flavonoids, tannins, coumarins, and cardioactive heterosides, as indicated by distinct O-H (3200-3600 cm-1), C-H (2850-2950 cm-1), and C=O (1700-1650 cm-1) stretching bands. The combined interpretation of phytochemical and FTIR data underscores the chemical diversity and functional group complexity of these plant extracts. Overall, the results highlight the nutritional and pharmacognostic significance of several Asteraceae species, supporting their potential application in antioxidant, nutraceutical, and therapeutic formulations.
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MakaleAçık Erişim2026Scopus SJRQ3/r/bayburt/10785
Ramadan intermittent fasting alters cardiac autonomic modulation, neuromuscular performance, and recovery in adolescent tennis players: a within-subject repeated-measures design
Lakhdar, Nadia; Landolsi, Mounir; Ghouili, Hatem; Ceylan, Halil Ibrahim; Ceylan, Nagihan Burcak; Muntean, Raul Ioan; Alsaeed, Mohammed Issa; Ben Said, Noureddine M.; Zaouali, Monia; Bouhlel, Ezzedine
Background: Tennis requires repeated high-intensity efforts with brief recovery periods, placing significant demands on cardiac autonomic regulation and neuromuscular performance. Ramadan intermittent fasting alters sleep, nutrition, and hydration patterns, potentially affecting match responses, particularly in adolescents. Methods: Sixteen male International Tennis Federation (ITF) junior players completed a within-subject repeated-measures study during mid-Ramadan and 15 days post-Ramadan. Each performed a standardized two-set outdoor match under both conditions. Heart rate variability (HRV), countermovement jump (CMJ), blood glucose, hydration markers, and rating of perceived exertion were assessed at baseline (T0), between sets (T1), and post-match (T2). Sleepiness, chronotype, fatigue, and recovery were evaluated via validated questionnaires. Results: Match play reduced lnRMSSD (p < 0.001, eta p(2 )= 0.775) and increased LF/HF (p < 0.001, eta p(2)= 0.234), indicating sympathetic dominance. During Ramadan, parasympathetic activity was lower (p < 0.001, eta p(2)= 0.269), and CMJ performance was reduced (p = 0.010, eta p(2)= 0.085). Blood glucose showed a Period & times; Set interaction (p = 0.020,eta p(2) = 0.114). Sleepiness, fatigue, and perceived recovery were significantly impaired (p < 0.001). Conclusion: Ramadan intermittent fasting reduces vagal activity and impairs neuromuscular performance in adolescent tennis players. HRV-guided training, optimized nutrition, and sleep management may help mitigate these effects.
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MakaleAçık Erişim2026Scopus SJRQ1/r/bayburt/10777
Acute Caffeine Ingestion, Calendar-Based Menstrual-Cycle Window, Time of Day, and Match-Induced Fatigue Independently and Interactively Influence Psychophysiological, Cognitive, and Physical Performance in Elite Female Volleyball Players: A Randomized Double-Blind Placebo-Controlled Crossover Design Study
Seddik, Meher; Dhahbi, Wissem; Bessifi, Manel; Moussa-Chamari, Imen; Ceylan, Halil Ibrahim; Ceylan, Nagihan Burcak; Muntean, Raul Ioan; Cular, Drazen; Souissi, Nizar
Aim: Female athletic performance is shaped by the convergence of menstrual-cycle timing, circadian rhythms, fatigue, and ergogenic supplementation; yet no prior study has examined these factors simultaneously in a sport-specific setting. This study investigated the independent and combined effects of acute caffeine ingestion, calendar-based testing window, time of day, and match-induced fatigue on psychophysiological, cognitive, and physical performance in trained female volleyball players. Methods: Thirteen elite eumenorrheic female volleyball players (age: 24.23 +/- 4.06 years) completed a randomized, double-blind, placebo-controlled crossover protocol comprising 12 sessions corresponding to all combinations of testing window (menstrual, follicular, luteal), supplementation (caffeine 6 mg & centerdot;kg(-1) vs. placebo), and time of day (08:00 h vs. 18:00 h). Assessments included the Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Spiegel questionnaire, Profile of Mood States, Hooper Index, Stroop task, Countermovement Jump (CMJ), Modified Agility T-Test (MAT), and Reactive Agility Test (RAT), administered before and after a one-hour simulated match. Results: Significant main effects of testing window, caffeine, time of day, and fatigue state were observed across all outcome domains (all p < 0.05). Caffeine reduced daytime sleepiness (F(1,12) = 23.84, p < 0.001, eta p(2) = 0.665), enhanced vigor (F(1,12) = 114.10, p < 0.001, eta p(2) = 0.905), and improved MAT performance (F(1,12) = 33.27, p < 0.001, eta p(2) = 0.735). The follicular window was associated with superior cognitive, neuromuscular, and mood-related outcomes relative to the menstrual and luteal windows. Exploratory higher-order interactions suggested condition-specific caffeine benefits for MAT, RAT, and CMJ, particularly in afternoon post-fatigue conditions; these patterns require replication in larger samples. Conclusions: Acute caffeine ingestion improved several psychophysiological, cognitive, and neuromuscular outcomes in trained female volleyball players, with effects that varied across calendar-based testing windows, time of day, and fatigue state. Individualized supplementation strategies incorporating cycle timing and circadian context remain investigational; prescriptive recommendations require replication in larger, hormonally verified samples before clinical or applied adoption.
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MakaleYalnız künye2026Scopus SJRQ2/r/bayburt/10775
The moderating effects of geopolitical risks on sustainable development through economic complexity and renewable energy consumption in 25 oil-producing countries
Ongan, Serdar; Özdemir, Dilek; Imamoglu, Ilyas Kays; Isik, Cem
Conflicts in controlling or using natural resources, arising from geopolitical risks (GPR), which have become a new normal today, can damage natural ecosystems and threaten sustainable development. In this context, GPR can turn the positive impact of supporting independent variables on sustainable development (SD) into a negative one. This research investigates the moderating effects of GPR on SD through renewable energy consumption (REN) and economic complexity (EC) in 25 oil-producing countries with relatively higher oil-reserve-related risks between 2000 and 2021. The panel quantile regression analysis reveals. (i) While using REN individually improves SD in countries with high SD (in the 80th and 90th quantiles), this improving effect turns to a worsening effect due to its interaction with GPR, which shows the moderating impact of GPR. (ii): While EC individually improves SD across all quantiles, these improving effects persist in countries with low SD (in the 10th, 20th, 30th, and 40th quantiles) even when complexity interacts with GPR, showing that GPR has no moderating impact on SD. Therefore, policymakers should investigate why the interaction of REN with GPR worsens SD in highly sustainable countries and redevelop regulatory renewable energy policies accordingly.
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MakaleAçık Erişim2026Scopus SJRQ1/r/bayburt/10767
The association of psychological need dissatisfaction with problematic digital gaming: Mediating roles of EPOCH well-being and resilience in adolescents
Yayla, Ibrahim Erdogan; Makas, Samet; Gomez-Salgado, Juan; Bayrakci, Cansu; Dombak, Kubra; Çelik, Eyup; Yildirim, Murat
Drawing on self-determination theory, this study examines how EPOCH well-being and resilience mediate the relationship between dissatisfaction with psychological needs and problematic digital gaming. Data were collected via questionnaires from 647 adolescents aged 13-19 (M = 15.80, SD = 1.10), 55.8% of whom were girls, using a convenience sampling method. Structural equation modeling was employed to test the proposed hypotheses. Results indicate a significant positive association between dissatisfaction with psychological needs and problematic digital gaming. Moreover, both EPOCH well-being and resilience were found to mediate this relationship. By highlighting the role of psychological resources in adolescence, this study makes novel theoretical and practical contributions to understanding the associations between psychological need dissatisfaction and problematic digital gaming. This is a cross-sectional study, which limits the generalization of the research results. The participants are adolescents attending middle schools in some rural areas of T & uuml;rkiye, which limits the generalizability of the research results to adolescents in other parts of T & uuml;rkiye and the world. Additionally, research data were obtained through self-report scales. This may lead adolescents to respond in line with their developmental perceptions of social desirability.
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MakaleAçık Erişim2026Scopus SJRQ2/r/bayburt/10762
Network comparison methods detect temporal reorganization of psychophysiological integration invisible to conventional univariate analysis: Proof-of-concept using lunar-phase-timed measurements in elite athletes
Yousfi, Narimen; Dhahbi, Wissem; Ghouili, Hatem; Mejri, Mohamed Arbi; Bessifi, Manel; Ceylan, Halil Ibrahim; Valentina, Stefanica; Ceylan, Nagihan Burcak; Chtourou, Hamdi; Dergaa, Ismail
Field studies using conventional univariate methods fail to detect physiological rhythms (melatonin, cortisol, sleep architecture) that are consistently documented under laboratory-controlled conditions, suggesting that temporal factors operate on systemic organization rather than isolated metrics. Network analysis quantifies conditional dependencies among variables simultaneously, enabling the detection of organizational changes independent of mean-level shifts. As an exploratory proof-of-concept, this study examines whether network comparison methods detect temporal reorganization of psychophysiological integration invisible to conventional repeated-measures analysis in elite athletes; no confirmatory causal inference is drawn. Twelve elite male athletes completed psychophysiological assessments (mood states, subjective well-being, neurocognitive performance, postural control, intermittent endurance) at three lunar phases (New Moon, First Quarter, Full Moon) in a counterbalanced design. Conventional repeated-measures ANOVA detected no temporal effects on isolated variables (all F < 2.87, p > 0.05, eta(2)p < 0.21). Network comparison revealed marked organizational differences: New Moon versus Full Moon networks exhibited distinct architecture (M = 0.31, padj = 0.008) and connectivity (S = 8.42, padj = 0.029). Centrality systematically redistributed from capacity and well-being constructs (New Moon: vigour z = 1.82) to recovery markers (Full Moon: stress z = 2.13). Twelve connections differed significantly, including enhanced stress-confusion coupling (Delta r = +0.39, p = 0.003). This proof-of-concept demonstrates that temporal measurements can exhibit systemic reorganization despite stable component means, resolving apparent contradictions between laboratory-detected physiological rhythms and field-based null findings. Temporal control measurements and multi-cycle replication are required to definitively attribute observed reorganization to lunar periodicity rather than generic temporal variation.
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MakaleYalnız künye2026Scopus SJRQ2/r/bayburt/10743
Novel heteroaromatic compounds bearing thiosemicarbazone as anti-cancer and anti-bacterial agents: Synthesis, cytotoxic and biological screening, molecular docking and DFT analysis
Nartop, Dilek; Ögütcü, Hatice; Özkan, Elvan Hasanoglu; Yetim, Nurdan Kurnaz; Kizil, Hamit Emre; Ekincioglu, Yavuz
Novel heteroaromatic compounds (Hc1, Hc2, Hc3, Hc4) were obtained, and their structure were confirmed using various spectroscopic methods, including elemental analysis, fourier transform infrared (FT-IR) spectroscopy, proton and carbon nuclear magnetic resonance (1H/13C-NMR) spectroscopy, and molar conductance measurement. The biological activities of the heteroaromatic compounds against several Gram-positive (Micrococcus luteus ATCC9341, Staphylococcus epidermidis ATCC12228, Bacillus cereus RSKK863, Listeria monocytogenes ATCC 19111), and Gram-negative bacterial strains (Pseudomonas aeruginosa ATCC27853, Klebsiella pneumonia ATCC27853, Enterobacter aerogenes ATCC51342, Salmonella typhi H NCTC9018394, Shigella dysenteriae NCTC2966, Proteus vulgaris RSKK96026) were evaluated using the well-diffusion method. In general, the heteroaromatic compounds demonstrated a stronger inhibitory effect against Gram-positive bacteria. Hc1, Hc2 and Hc3 showed the highest inhibitory effect against B. cereus and L. monocytogenes. The compound (Hc4) showed the highest antibacterial activity and antifungal activity against Bacillus cereus and C. albicans, respectively. The cytotoxic activity of the heteroaromatic compounds was assessed against the non-small cell lung cancer cell line (NCI-H460) using the NutriCulture Cell Viability Detection Kit-8 (CVDK-8). Among the synthesized heteroaromatic compounds, Hc3 exhibited significant cytotoxic activity with an IC50 value of 141.3 & micro;g/mL, whereas compounds Hc1, Hc2, and Hc4 did not display significant toxicity at the tested concentrations. The molecular geometry of the heteroaromatic compound (Hc3) was optimized using Gaussian 09 W at the B3LYP/6-311++G (d,p) level of theory. Key structural parameters such as bond lengths, bond angles, and dihedral angles were determined through the same computational framework. Electronic features, including frontier molecular orbitals, global reactivity descriptors, and molecular electrostatic potential surfaces, were analyzed to explore intramolecular charge distribution and predict reactive sites. To evaluate the biological potential of the heteroaromatic compound (Hc3), molecular docking studies were performed. Additionally, drug-likeness assessment based on Lipinski's Rule of Five and ADME profiling revealed favorable pharmacokinetic characteristics. Molecular docking studies revealed that compound Hc3 showed a binding energy of -4.09 kcal/mol against the EGFR target (PDB ID: 1UWH), exhibiting key interactions such as hydrogen bonding and It-interactions with the active site residues. Based on all the results, it can be said that new heteroaromatic compounds have significant potential in the pharmaceutical field.
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MakaleAçık Erişim2026Scopus SJRQ1/r/bayburt/10736
High Prevalence of Malnutrition and Sarcopenia with Inadequate Nutritional Support in Intensive Care Unit Patients: A Prospective Observational Study of Clinical Outcomes
Ben Othman, Rym; Cherni, Asma; Dergaa, Ismail; Ceylan, Halil Ibrahim; Ceylan, Nagihan Burcak; Stefanica, Valentina; Sedghiani, Ines; Borsali, Nebiha; Jamoussi, Henda
Background: Malnutrition and sarcopenia are highly prevalent in intensive care settings and are associated with adverse clinical outcomes. Aim: The study aimed to evaluate the association between nutritional care, nutritional status, and patient outcomes in intensive care units. Methods: This prospective observational study at a Tunisian tertiary hospital investigated nutritional status and management of 100 intensive care unit patients, each of whom was followed for seven days after ICU admission. Malnutrition Risk was assessed by NUTRIC and MNA scores. The severity of disease was assessed using the APACHE II and SOFA scores. Malnutrition was diagnosed using body mass index and weight loss. Sarcopenia was assessed through grip strength, calf circumference, and psoas muscle area. Nutritional management was evaluated using calculations of caloric and protein intake. Clinical outcomes included the need for intubation, difficulty with oxygen weaning, healthcare-associated infections, and the development of pressure ulcers. Results: The participants had a mean age of 54.85 +/- 17.25 years, with a slight male predominance (53 males, 47 females). Pre-existing metabolic conditions affected 80% of patients, including hypertension (40 patients), diabetes (36), and obesity (18). The primary reasons for admission were respiratory disorders (25%), infectious diseases (23%), and metabolic disorders (16%). The mean APACHE II score was 15.91 +/- 6.84, and the mean NUTRIC score was 3 +/- 1.66; 27% were classified as at high risk of malnutrition. The prevalence of malnutrition reached 50% (28% moderate, 22% severe). Only 31% received adequate caloric intake, while 84% had insufficient protein intake. Malnourished patients required intubation more frequently (50% versus 22.5%; p = 0.014), experienced greater difficulty with oxygen weaning (78.4% versus 48.6%; p = 0.008), and developed pressure ulcers more often (43.5% versus 6%; p < 0.001). Sarcopenic patients showed similar patterns for intubation (51.4% versus 18.9%, p = 0.003), oxygen weaning difficulty (77.5% versus 46.9%, p = 0.007), and pressure ulcers (39.2% versus 6.7%, p < 0.001). Conclusions: Malnutrition and sarcopenia are highly prevalent in intensive care patients and are associated with severe complications, including prolonged mechanical ventilation and pressure ulcer development. Inadequate nutritional support remains common despite known consequences. Early comprehensive nutritional assessment and appropriate management from admission are essential to improve outcomes in critically ill patients.
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MakaleAçık Erişim2025/r/bayburt/16241
Farmers as a consumers: utaut with dual moderated mediation model
Yilmazel, Sefa Emre
The purpose of the study is to determine the factors that affect the adoption and implementation of clean and energy efficient practices by farmers. For this reason, in line with the model developed within the scope of UTAUT, it was investigated whether two moderator variables (environmental concern, financial benefits) make a difference for clean and energy practices. Data were collected from 400 participants for clean production and 400 participants for energy-efficient production. The data obtained were analyzed with Process Macro model 4 and model 21 developed by Hayes. As a result, it was seen that the UTAUT variables had a significant effect on farmers' adoption intention in both data. In addition, the moderating effect of adoption intention on the relationship between UTAUT variables and usage behavior was proven. Furthermore, the effect of both moderator variables in the study was revealed. While environmental concern has a moderating effect between performance expectancy, effort expectancy and facilitating conditions and adoption behavior in the clean production. Financial benefits has a significant moderating effect between adoption intention and usage behavior for all four of the UTAUT variables in the energy efficient production.
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MakaleAçık Erişim2025/r/bayburt/16235
Theoretical Investigation of the Molecular Properties of the Fluoroaniline and Fluoroanisole Isomers
Kepceoğlu, Abdullah; Ekincioğlu, Yavuz
This research paper aims to analyse the molecular properties of fluoroaniline and fluoroanisole isomers through a range of theoretical methods. These methods include optimization of molecular structures, conformational analysis, and calculation of nonlinear optics (NLO) properties, frontier molecular orbital (HOMO-1, HOMO/SOMO, LUMO, LUMO+1) energies, chemical reactivity descriptors (ionization potentials - vertical and adiabatic, electron affinity, chemical hardness, softness, and electronegativity), molecular electrostatic potential (MEP), natural bonding orbital (NBO), and UV-Vis spectra. To achieve this, the density functional theory method with B3LYP functional and 6-311++G (d, p) basis set were used for the calculations. Additionally, the research examines the vertical and adiabatic ionization energy parameters of the molecules by constructing singly charged cation radicals. The outcome of this study provides valuable insights into the molecular properties of fluoroaniline and fluoroanisole isomers, which can be useful in the production of pharmaceuticals and agrochemicals.
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MakaleAçık Erişim2025/r/bayburt/16234
Duygusal zeka ve iletişim becerileri arasındaki ilişki: türkiye örneğinde bir meta-analiz
Battal, Fetullah
Bu çalışmanın amacı ve kapsamı, ulusal/uluslararası hakemli dergilerde yayınlanmış, Türkiye odaklı örneklemlerden elde edilen ampirik verilerden yararlanan makaleler üzerinden,duygusal zeka ve iletişim becerileri arasındaki doğrudan ilişkiyi incelemektir. Bu ilişkinin ortaya koyulması için CMA programı yardımıyla meta analiz yöntemi tercih edilmiştir.Çalışma sonucunda korelasyon değerleri bulunan yirmibeş makalenin orta-yüksek seviyede pozitif yönlü ve anlamlı olarak ilişkilerinin bulunduğu görülmüştür (EB=-0,460, p<0,00).Aynı zamanda incelenen ampirik çalışmaların içerisinde iki adet çalışmanın negatif yönlü ve zayıf korelasyon düzeylerine sahip olduğu görülmüştür.Bu araştırmanın gerçekleştirilmesindeki temel sorulardan biriside duygusal zeka ve iletişim becerileri arasındaki ilişki üzerine yapılmış analizlerin genel resmini ortaya koyarak gelecekte ilgili konular hakkında çalışma yapacacak potansiyel araştırmacılara rehberlik etmektir. Meta analiz çalışmaları kümülatif sonuçları içerdiği için hem ulusal yazında hemde uluslararası yazında ampirik çalışma yapmak isteyen araştırmacılara önemli bir katkı sunacaktır. Ayrıca duygusal zekanın iletişim becerileri ile ilişkileri örgütteki yöneticiler tarafından doğru yönetilirse olumlu sonuçların alınabileceği ve sürdürülebilir rekabet avantajı sağlayabileceği düşünülmektedir. Gelecekte yapılacak çalışmalarda duygusal zekanın öncülleri veya sonuçları açısından daha kapsamlı bir değerlendirme yapılabilir ve bu çalışmanın sonuçları yardımıyla daha genel bir çerçeve sunulabilir. Bu haliyle çalışmanın sonuçları hem tekil düzeyde hemde meta analiz düzeyinde literatüre özgün bir katkı sunmaktadır.
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MakaleAçık Erişim2025/r/bayburt/16233
Assessment of Nucleic Acid Extraction Kits for SARS-CoV-2 Surveillance in Wastewater Samples
Bayraktar, Bülent; Aslan, İsmail; Korkmaz, Serol; Parmaksız, Ayşe; Sait, Ahmet
Objective: The aim of this study is to evaluate the effectiveness of three commercial nucleic acid extraction kits (kit A, B and C) in isolating SARS-CoV-2 viral RNA from wastewater samples. Method: In this study, water samples were collected in March 2021 from three wastewater treatment plants located in different parts of Istanbul, and it was confirmed that they were negative for SARS-CoV-2. Different concentrations of the SARS-CoV-2 virus, previously inactivated at the BSL-3 laboratory of the Pendik Veterinary Control Institute, were added to the wastewater samples. RNA extraction and quantification were performed using commercial nucleic acid extraction kits and and RT-qPCR kit specific to SARS-CoV-2. Results: At the end of the study, it was determined that kit C yielded the highest total RNA and produced more consistent results, significantly outperforming the other two kits in terms of RNA yield and purity. Statistical analysis revealed significant differences in RNA concentrations (p < 0.05) and gene copy numbers (p < 0.01) between the kits, and kit C demonstrated superior linearity and reproducibility. Conclusion: According to the findings, although all three evaluated kits are suitable for detecting SARS-CoV-2 RNA in wastewater samples, kit C provides the most efficient and reliable performance, especially for high-throughput studies. Additionally, this study highlights the importance of selecting appropriate nucleic acid extraction methods for wastewater surveillance, which serves as an early warning system for outbreaks that threaten public health.
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MakaleAçık Erişim2025/r/bayburt/16227
Farklı Ekolojik Koşullarda Yetiştirilen Lavandin (Lavandula x intermedia Emeric Ex Loisel.) Bitkisinin Antioksidan Aktivitesi ve Uçucu Yağ Bileşenlerinin Mikrodalga hidrodistilasyon ile Belirlenmesi
Gıdık, Betül; Sağlam, Nilay Özlem
Tıbbi aromatik bitkiler her geçen gün önemi ve kullanım alanları artan değerli bir bitki grubu halini almaktadır. Özellikle uçucu yağlar yakın zamanlarda sıkça günlük hayatımızda kullanılmaktadır. Lavandin (Lavandula x intermedia Emeric ex Loisel.) çiçek kısımlarında uçucu yağ elde edilen ve parfümeri sanayii başta olmak üzere birçok alanda kullanılan ekonomik değeri olan bir bitkidir. Bu çalışmanın amacı; farklı ekolojik koşullarda yetiştirilen Lavandin bitkisinin antioksidan aktivitesi ve uçucu yağ bileşenlerini belirleyerek ekolojik farklılıkların bu değişkenler üzerindeki etkilerini ortaya koymaktır. Bu amaçla farklı lokasyonlarda yetiştirilen lavandin örneklerinin mikrodalga hidrodistilasyon yöntemi ile elde edilen uçucu yağ oranlarının %0,5-%4,4 değerleri arasında değiştiği görülmüştür. Majör uçucu yağ bileşenlerinin linalool (%13,66-%26,40) ve linalilyl asetat (%10,88-%29,89) olduğu görülmüştür. Lavandin örneklerine ait TP (Toplam fenolik madde) 2,13-4,74 mg GAE/g numune değerleri arasında, TF (Toplam flavonoid madde) 0,43-0,66 mg QE/g numune değerleri arasında, FRAP (Demir (III) indirgeme) 27,62-79,50 µmol Fe2SO4.7H2O/g numune değerleri arasında ve DPPH (radikal temizleme aktivitesi) ise 0,54-1,84 SC50 mg/mL değerleri arasında olduğu belirlenmiştir. Elde edilen sonuçlar, ekolojik koşulların lavandin bitkisi için antioksidan aktivitesi ve uçucu yağ oranında etkili olduğunu ve çalışmada kullanılan bitki materyallerinin parfümeri sanayiinde kullanıma uygun olduğu fikrini desteklemektedir.
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MakaleAçık Erişim2025/r/bayburt/16224
Yetişkin Bireylerin Üçüncü El Tütün Dumanına Yönelik İnanışları ve Etkileyen Faktörler
Terzi, Handan; Sönmez Sarı, Ebru
Amaç: Bu araştırma yetişkin bireylerin üçüncü el tütün dumanına yönelik inanışlarını ve etkileyen faktörleri belir- lemek amacıyla yapıldı. Materyal ve Metot: Kesitsel tipteki araştırmanın örnekle- mi, Türkiye’de toplumda yaşayan yetişkin bireylerden oluşturuldu (n=835). Veriler, 10 Haziran-31 Temmuz 2021 tarihleri arasında anket formu ve Üçüncü El Dumana Yönelik İnançlar Ölçeği kullanılarak toplandı. Veriler, IBM SPSS v.25.0 programında tanımlayıcı istatistikler, karşılaştırmalı analizler ve çoklu doğrusal regresyon anali- zi kullanılarak test edildi. İstatistiksel anlamlılık düzeyi p<0,05 kabul edildi. Bulgular: Katılımcıların yaş ortalaması 29,10±9,76 olup, %74,9’unun kadın, %64,8'inin ev sahibi ve %85,3'ünün üçüncü el duman kavramını daha önce duymadıkları belir- lendi. Üçüncü El Dumana Yönelik İnançlar Ölçeği'nin toplam puan ortalamasının 4,30±0,64 olduğu bulundu. Kadınların, kırsal bölgede yaşayanların, üçüncü el duman kavramını daha önce duyanların, sigara içmeyenlerin, sigara içilmesine izin verilen yerlerde bulunmayı tercih etmeyenlerin ve evlerinde sigara içilmesi tamamen yasak olan yetişkin bireylerin Üçüncü El Dumana Yönelik İnançlar Ölçeği'nin toplam puan ortalamasının daha yük- sek olduğu belirlendi (R2= 0,079; F=7,064; p<0,001). Sonuç: Yetişkin bireylerin üçüncü el dumana ilişkin inanç düzeylerinin yüksek olduğu belirlendi. Çalışma sonuçları- nın, toplumda yaşayan yetişkin bireylerin sigarayı bırakma motivasyonunu artırmak için yapılacak çalışmalara katkıda bulunacağı düşünülmektedir. Yetişkinlerin üçüncü el du- mana ilişkin inançlarının belirlenerek bilgi ve farkındalık- larını artırmaya yönelik deneysel çalışmaların yapılması önerilir.
AtıfOpenAlex2
İncele
MakaleAçık Erişim2025/r/bayburt/16212
Alkali Aktifleştirilmiş Uçucu Kül ve Polipropilen Elyaf Ile Iyileştirilmiş Yüksek Plastisiteli Siltli Zeminin Durabilite Performansının Incelenmesi
Kamiloğlu, Hakan Alper; Kurucu, Kutluhan; Durak, Muhammet Oğuz
Bu çalışmada aktivatör içeriği, fiber takviye türü ve fiber içeriği gibi parametrelerin durabilite özellikleri üzerindeki etkileri araştırılmaktadır. Geleneksel yöntemler durabilite değerlendirmesi için genellikle ıslatma-kurutma veya donma-çözülme döngülerine odaklanırken, bu çalışma saha koşullarını daha doğru bir şekilde simüle eden ıslatma testlerinin önemini vurgulamaktadır. Zemin iyileştirme uygulamalarında, malzemenin kırılganlığı hem geleneksel hem de alkali ile aktive edilen bağlayıcıların kullanımı ile artmaktadır. Lif takviyesi, bu sorunu çözmek ve sünekliği artırmak için yaygın bir uygulamadır. Bu çalışma, çeşitli lif türlerini ve bunların zemin özelliklerinin farklı yönlerini iyileştirmedeki rollerini incelemektedir. Özellikle, farklı tip ve uzunlukları bir araya getiren hibrit liflerin kullanımı, zemin tabakalarının durabilite özelliklerini artırma potansiyeli açısından araştırılmıştır. Çalışmanın deneysel kısmı, lif takviyesi ve alkali ile aktive edilmiş uçucu kül ile stabilize edilmiş yüksek plastisiteli siltli zeminin ıslatma etkilerine karşı davranışını araştırmaktadır. Çalışma, Na2SiO3/NaOH oranının, 3 mm ve 12 mm uzunluğundaki lif içeriğinin ve bu lif uzunluklarının kombinasyonlarının bozulma, serbest basınç dayanımı (UCS) ve ıslatılmış numunelerin dayanım azalması üzerindeki etkilerini ele almaktadır. Numunelerin dayanıklılık performansı çeşitli ıslatma süreleri ile değerlendirilmiştir. Sonuçlar, farklı uzunluklarda karıştırılan hibrit liflerin kullanımının, stabilize edilmiş zeminin durabilite özelliklerini iyileştirmede dikkate değer katkı sunduğu belirlenmiştir.
İncele
MakaleAçık Erişim2025/r/bayburt/16211
Some Physical Attributes of a Cr-Doped Iron Oxide Thin Film Produced by Simultaneous RF and DC Magnetron Sputtering Technique
Şenay, Volkan; Sarıtaş, Sevda; Salari, Maryam Abdolahpour; Muğlu, Günay Merhan
Iron oxide has recently attracted considerable interest because of its diverse structural and morphological configurations, leading to progressions in various technologies, including ultrahigh magnetic storage, magneto-optical sensors, humidity sensors, and gas sensors. In this research, a thin film of iron oxide doped with chromium was produced on a glass substrate using simultaneous RF and DC magnetron sputtering. The resulting thin film's optical, structural, elemental, and surface characteristics were thoroughly investigated using UV-VIS spectroscopy, XRD, XPS, AFM, and SEM. XRD was utilized to examine the structure of the thin film, which demonstrated good crystallinity. Notably, prominent diffraction peaks at various angles corresponded to specific planes of the normal hematite phase of Fe2O3, as verified by the JCPDS Card No. 33-0664. A significant peak at (104) indicated a sturdy development of the hematite phase. The XPS spectrum analysis approved the presence of iron, oxygen, and chromium in the thin film. This study, known for its straightforward methodology, provides valuable insights into the chromium impurity doping process of Fe2O3, contributing to a deeper understanding of its structural and morphological characteristics.
İncele
MakaleAçık Erişim2025/r/bayburt/16208
Berberis vulgaris L. Ekstraktının Dana Köftelerinin Fizikokimyasal, Duyusal ve Tekstürel Özelliklerine Etkisi
Topcu, Kübra Cinar; Ugur, Gamze
Farklı konsantrasyonlarda (%0,1, %0,2 ve %0,4) Berberis vulgaris meyve ekstraktı eklenmesinin çiğ sığır köftelerinin fizikokimyasal özellikleri üzerindeki etkileri araştırılmıştır. Ayrıca, pişmiş sığır köfteleri üzerinde fizikokimyasal, duyusal ve tekstürel analizler yapılmıştır. Ekstraktın ilavesi, köftelerin yaklaşık bileşiminde önemli bir değişikliğe neden olmamıştır. pH değerlerindeki değişim, tüm gruplarda anlamlı şekilde etkilenmiştir (P<0.01). İlk başta, TBARS değerini tüm gruplarda önemli ölçüde etkilemiştir (P<0.05). Ancak, pişirme sonrasında TBARS değerlerinde önemli bir fark gözlenmemiştir (p>0.05). Pişirmeden önce renk değerlerinde anlamlı bir fark gözlenmezken, pişirme L*, a* ve b* değerlerini azaltmıştır. Pişirme verimi, tüm grupları önemli ölçüde etkilemiştir (P<0.01). Köftelere Berberis ekstraktı eklenmesi pişirme verimini azaltmıştır. Ekstraktın ilavesi, köftelerin duyusal özelliklerinde istatistiksel olarak anlamlı bir değişiklik oluşturmamıştır. Ayrıca, tekstür analizi, tüm gruplarda sertlik, yapışkanlık ve çiğnenebilirlik değerleri üzerinde yüksek derecede anlamlı etkiler ortaya koymuştur (P<0.01). Sonuçlar, ekstraktın köftelerin fizikokimyasal özelliklerini kayda değer şekilde değiştirmediğini göstermektedir. Ancak, lipid oksidasyonunu etkili bir şekilde azaltır ve onların tekstürel niteliklerini artırır. Bu çalışma, sığır köftelerinin kalitesini artırmak için B. vulgaris ekstraktının doğal bir katkı maddesi olarak potansiyel kullanımını desteklemektedir.
AtıfOpenAlex1
İncele
MakaleAçık Erişim2025/r/bayburt/16206
Examination of studies on scientific process skills in science education through bibliometric and content analysis
Arici, Faruk
This study presents a comprehensive analysis of academic research on scientific process skills (SPS) in science education using meticulously extracted data from the Web of Science (WoS) database. A holistic approach was employed in the research, integrating bibliometric analysis and content analysis to reveal general trends and thematic structures in the literature. Specifically, bibliometric analysis was employed to examine the most frequently cited studies on inter-author collaborations and keyword trends on SPS. Content analysis provides a unique contribution to our study by detailing the analysis of these publications. A distinguishing feature of this study is the use of a more extensive data set and a more extended period than previous studies, providing a more comprehensive picture of the evolution of research on SPS over time. The VosViwer bibliometric analysis software employs an array of analytical methods, including citation analysis, co-author analysis, keyword matching, and collaboration network analysis, to identify trends within the field. The analysis encompasses studies published from the inaugural study in 1992 through August 2024. The findings reveal a substantial increase in publications, with 2020 demonstrating the highest number of publications. In contrast, the average number of publications during the preceding five-year period was restricted to eight per year. Most of these publications are classified under "Education, Educational Research," with a smaller number falling under "Biology." This observation suggests that the primary focus of SPS research is within the educational context. Furthermore, the study revealed that publications in the SSCI and ESCI indexes are more prevalent, while there are fewer studies in the SCI-E index. The prominent researchers in this field include Kamisah Osman, Hatice Zeynep Inan, and Susan A. Kirch. A notable observation was Turkey's high ranking in terms of country distribution. This observation indicates that researchers have dedicated significant attention to the SPS in the context of science education. The most prevalent keywords in the analyzed studies were "SPS," "science education," "inquiry," and "assessment." Over time, there has been an upward trend in the use of terms such as "inquiry-based learning," "teacher education," and "elementary education." The most prominent academic journals in this field include the Journal of Research in Science Teaching and the International Journal of Science Education. Notwithstanding the strides made, the study underscores Turkish researchers' need to enhance their visibility and cultivate national journals to attain international standards.
AtıfOpenAlex1
İncele
MakaleAçık Erişim2025/r/bayburt/16205
CO2 Emissions Forecast Based on Renewable and Non-Renewable Energy Consumption in Türkiye
Eygu, Hakan; Coşkun, Hüseyin
This study aims to reveal the impact of renewable and non-renewable energy consumption on CO2 emissions in Türkiye and the potential to reach the CO2 emission level targeted in the 2030 Paris Agreement. In the first stage, the cointegration relationship was analyzed with the AARDL model approach using annual data for 1965-2022. According to the results of the analysis, in the long run, non-renewable energy consumption increases CO2 emissions, while renewable energy consumption decreases CO2 emissions. In the second phase of the research, three scenarios were prepared for each of renewable and non-renewable energy consumption. For nine scenarios, including combinations of these scenarios, CO2 emissions that may occur until 2030 were estimated using the econometric simulation method. According to the estimation results, the low non-renewable energy consumption and high renewable energy consumption scenario was determined as the scenario that can reduce CO2 emissions the most until 2030. However, even in this case, it is understood that more investment in renewable energy will be required since the 2030 CO2 emission reduction target will not be achieved. Therefore, policymakers need to enact policies to increase incentives for renewable energy generation in both the public and private sectors and take steps to improve the necessary infrastructure.
AtıfOpenAlex4TR Dizin1
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