Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Dertli, Enes(114)
- Kaya, Yunus(48)
- Şahin, Engin(48)
- İspirli, Hümeyra(47)
- Özen, Soner(38)
- Şenay, Volkan(37)
- Pat, Suat(36)
- Kutlu, Naciye(32)
- Artar, Musa(31)
- Can, Zehra(31)
- Korkmaz, Şadan(31)
- Yilmaz, Mustafa Tahsin(31)
- Öner, Erdal(31)
- Bayram, Sinan(30)
- Cuce, Erdem(30)
- Ertugrul, Mehmet(29)
- Hasar, Ugur Cem(29)
- Ecem Bayram, Nesrin(28)
- Mercan, Emin(28)
- Ayata, Ümit(27)
- Bayraktar, Bülent(27)
- Çolak, Murat(23)
- Özdemir, Akın(23)
- Ayazoglu, Rabil(22)
- Cuce, Pinar Mert(22)
- Sert, Durmuş(22)
- Bayram, Ozkan(21)
- Kamiloğlu, Aybike(21)
- Dirican, Ebubekir(20)
- Kadakal, Mahir(20)
- Abdioglu, Murat(19)
- Birinci, Ahmet(19)
- Tozlu, Alperen(19)
- Gerçek, Yusuf Can(18)
- Taylan, Osman(18)
- Cinar, Mehmet(17)
- Gul, Volkan(16)
- Hasar, Ugur C.(16)
- Kadakal, Huriye(16)
- Kara, Yakup(16)
Yayınlar
- MakaleAçık Erişim2024Scopus SJRQ3Occupational Safety and Hidden Risks in a Furniture Factory: A Comprehensive Assessment of Hazards Related to Noise, Lighting, Thermal Comfort, and Dust Exposure
Özdemir, Mustafa; Albayrak, Sirer
This study assessed the occupational health and safety conditions in a furniture manufacturing facility, focusing on key environmental factors such as noise, lighting, thermal comfort, and dust exposure. Noise measurements recorded levels as high as 95.3 dB(A) during CNC machine operations, exceeding legal exposure limits of 87 dB(A), posing significant risks to workers’ hearing health. Lighting assessments showed levels ranging from 134 to 247 lux in production lines, which falls below the recommended threshold of 300 lux for adequate visibility. Thermal comfort was evaluated with temperature readings at 14.2 °C and relative humidity at 43%, revealing marginal comfort conditions that could reduce worker efficiency and satisfaction. Dust exposure measurements indicated respirable dust concentrations reaching 3.69 mg/m³ in the cutting department, which is close to the permissible exposure limit of 5 mg/m³, raising concerns about long-term respiratory health. These findings suggest several measures to improve workplace safety, including enhanced engineering controls, mandatory personal protective equipment (PPE), improved lighting systems, optimised thermal conditions, and advanced ventilation to reduce dust exposure. This comprehensive evaluation provides critical insights for improving furniture factories’ occupational health and safety practices.
AtıfScopus6WoS6OpenAlex3
İncele - DüzeltmeAçık Erişim2024Scopus SJRQ1Correction to: Salivary apelin hormone response and dysfunctional attitudes in adolescents in Türkiye: a relational screening model (BMC Psychology, (2024), 12, 1, (64), 10.1186/s40359-024-01551-w)
Kirbaş, Zila Özlem; Bayraktar, Bülent; Aktaş, Elif Odabaşi
Following publication of the original article, it came to the journal’s attention that the order of the citations (following citation of reference 22) was incorrect. The order has since been corrected in the published article.
AtıfScopus1WoS1OpenAlex1
İncele - MakaleAçık Erişim2024Scopus SJRQ1Energy-driven TBM health status estimation with a hybrid deep learning approach
Li, Yongsheng; Zhang, Limao; Pan, Yue; Tapkın, Serkan; Song, Xieqing
This study provides a hybrid deep learning approach that enables the researchers to estimate the Tunnel Boring Machine (TBM) health status during excavation process using energy consumption data. By analyzing the energy forms and paths in the tunneling process, the key energy factors' consumption performance behavior affecting TBM safety is identified. The Ensemble Empirical Mode Decomposition (EEMD) method and a Convolution neural network-Long short term memory-Depth Neural Network (CNN-LSTM-DNN, CLDNN) model are integrated for Health Performance Parameter (HPP) prediction. A classification method is constructed by the Generative Adversarial Imputation Networks (GAIN) model for health status estimation. The SHapley Additive exPlanations (SHAP) method is performed to quantify the relationships between energy consumption and system health status. A tunneling case in Singapore is used to test the effectiveness of the developed methodology. It is found that (1) the proposed method provides TBM cutter wear and cooling oil prediction with a R-square (R2) of 0.8591 and 0.8727, respectively, and (2) classification results indicate that the estimation F1-score of 0.9863 can be achieved based on health status evaluation indicator (HSEI). The novelty of the proposed approach lies in its capabilities of (1) fully extracting and utilizing the energy consumption information in every regard to predict TBM health performance; (2) providing a good one-step-ahead health status estimation for the TBM excavation process. Therefore, this study proposes a feasible direction for the application of energy consumption data in TBM health status estimation.
AtıfScopus17WoS15OpenAlex17İncele - MakaleYalnız künye2024Scopus SJRQ1Variations of natural frequencies of masonry minarets due to environmental effects
Yanik, Yusuf; Aymelek, Abdullah; Yildirim, Ömer; Demirtaş, Betül; Türker, Temel
It is very important to distinguish the reason of change in natural frequencies of structures either caused by a possible damage or environmental conditions (temperature and humidity). In this study, the changes in the dynamic properties of masonry and reinforced concrete minarets under environmental effects, such as temperature and humidity, were investigated. The masonry minarets of İskenderpaşa, Hacı Kasım, and Tavanlı Mosques and the reinforced concrete minarets of Karadeniz Technical University, Dilaveroğlu and Papatya Mosques in Trabzon were monitored by ambient vibration test method, and the relationship between natural frequencies and temperature and humidity was tried to be determined. For this purpose, the natural frequencies of these minarets were measured at certain intervals under different temperature and humidity conditions over a period of approximately 6 months. The vibration measurement system which was developed by our research team was used in the measurements. From the data collected by these measurements, the variation intervals of the natural frequencies (the smallest and the highest values), the percentages of change and their relations with temperature and humidity were revealed. This relationship was determined using linear–non-linear simple and multiple regression analyses. From this study, it was found that the natural frequencies change under environmental effects, such as temperature and humidity, and this rate of change was approximately 7%. There was moderate correlation in Tavanlı, Dilaveroğlu, and Papatya Minarets, and strong correlation in Hacı Kasım Minaret.
AtıfScopus16WoS17OpenAlex16İncele - MakaleYalnız künye2024Scopus SJRQ2Endoscopic Resection of Nasal Septal Chondroma
Demir, Murat; Bahadır, Osman; Çobanoğlu, Hatice Bengü
Chondromas are benign cartilaginous tumors and rarely develop in the nasal septum. Although it causes different symptoms depending on the location and size of the tumor, the most common complaints are nasal obstruction and epistaxis. A submucosal mass narrowing the nasal passage can be seen in the septum by an endoscope. Computed tomography gives information about the localization and size of the mass. A definitive diagnosis is made by histopathologic examination. Treatment is surgical excision. Endoscopic surgery provides a less invasive and successful treatment. This case series aims to share that 2 cases with a diagnosis of nasal septal chondroma were successfully treated with endoscopic surgery.
- MakaleAçık Erişim2024Scopus SJRQ3Unveiling the significance of Gremlin-1 as a novel biomarker for enhanced severity prediction in COVID-19 patients
Celik, Muhammet; Tekin, Erdal; Koçak, Mehmet Nuri; Uzunçakmak, Sevgi Karabulut; Bayraktar, Mustafa
Gremlin-1 is associated with lung disease and plays a role in the initiation and progression of pulmonary fibrosis. This suggests that Gremlin-1 may be associated with lung involvement in COVID-19 and poor clinical outcomes and warrants further investigation. This prospective, cross-sectional, single-blind study was the first to investigate Gremlin-1 levels in COVID-19 patients and whether Gremlin-1 levels could be used to predict and guide clinical follow-up in outpatients and inpatients. In this context, serum Gremlin-1 levels were measured and compared in 2 groups of patients who were diagnosed as positive for COVID-19 by RT-PCR and were followed up as outpatients (n = 28) or required hospitalization (n = 30). The median Gremlin-1 values were statistically significantly different between outpatients and intensive care unit patients (0.367 ng/mL [IQR = 0.377], 1.858 ng/mL [IQR = 2.245], respectively) (P < .0001). The area under the ROC curve value to determine the discriminative power of Gremlin-1 was found to be 0.772 (95% CI: 0.672-0.871; P < .0001), and the cutoff value of Gremlin-1 to discriminate between outpatients and hospitalized patients was found to be 1.242 ng/mL with 66.7% sensitivity and 67.2% specificity. Serum Gremlin-1 level is an important biomarker that can be used as a clinical decision-making tool for COVID-19 positive patients.
AtıfScopus2WoS2OpenAlex3İncele - MakaleAçık Erişim2024Scopus SJRQ1Thermal and energy analysis of a novel solar updraft tower design with divergent chimney and convergent collector concept: CFD analysis with experimental validation
Cuce, Pinar Mert; Saxena, Abhishek; Cuce, Erdem; Kontoleon, Karolos J.; Oztekin, Erman K.; Shaik, Saboor; Guo, Shaopeng
The fact that energy sources are heavily dependent on fossil fuels increases the need for alternative energy day by day. Solar energy is the most popular alternative energy source with massive potential. Solar chimney power plants (SCPP) are one of the systems of interest based on solar energy. SCPP systems are rare systems that can provide 24-hour power output. Their performance has been the subject of constant research since the first pilot plant in Manzanares. Design is crucial for performance figures of SCPPs, and the limitation of climatic parameters causes the system to be approached with different designs. This study makes a 3D CFD model by combining the divergent chimney and convergent collector structure based on the first pilot plant. The solar ray tracing algorithm and the RNG k-e turbulence model are applied and the model equations are solved under dynamic conditions with the reliable software ANSYS FLUENT. After the mesh-independent solution of the model is complete, it is validated with experimental data. The two cases are compared for solar radiation of 1000 W/m2 and environmental temperature of 293 K. A power output of 50.51 kW is achieved for standard pilot sizing. With the new model, the power output rises to 146.34 kW. It is seen that the divergent chimney and convergent collector affect the airflow in the system, increasing the maximum air velocity to 19.363 m/s. In parallel with the experimental data, it is seen that the temperature on the ground exceeds 360 K in the CFD results.
AtıfScopus17WoS12OpenAlex14İncele - MakaleYalnız künye2024Scopus SJRQ2A dual-acting aldose reductase inhibitor impedes oxidative and carbonyl stress in tissues of fructose- and streptozotocin-induced rats: comparison with antioxidant stobadine
Kaya, Alican; Ceylan, Aslı F.; Kavutcu, Mustafa; Santamaria, Abel; Šoltésová Prnová, Marta; Stefek, Milan; Karasu, Çimen
Inhibiting aldose reductase (ALR2, AR) as well as maintaining a concomitant antioxidant (AO) activity via dual-acting agents may be a rational approach to prevent cellular glucotoxicity and at least delay the progression of diabetes mellitus (DM). This study was aimed at evaluating the dual-acting AR inhibitor (ARI) cemtirestat (CMTI) on tissue oxidative stress (OS) and carbonyl stress (CS) biomarkers in rats exposed to fructose alone (F) or fructose plus streptozotocin (D; type-2 diabetic). D and F rats were either untreated or treated daily with low- or high-dose CMTI, ARI drug epalrestat (EPA) or antioxidant stobadine (STB) for 14 weeks. Malondialdehyde (MDA), glutathione S-transferase (GST), nitric oxide synthase (NOS), and catalase (CAT) were increased in the sciatic nerve of F and D. These increases were attenuated by low doses of CMTI and STB in D, but exacerbated by low-dose EPA and high-dose CMTI in F. STB and CMTI and to a lesser extent EPA improved MDA, protein-carbonyl, GST and CAT in the hearts and lungs of F and D. CMTI and STB were more effective than EPA in improving the increased MDA and protein-carbonyl levels in the kidneys of F and especially D. CMTI ameliorated renal GST inhibition in D. In the lungs, hearts, and kidneys of F and D, the GSH to GSSG ratio decreased and caspase-3 activity increased, but partially resolved with treatments. In conclusion, CMTI with ARI/AO activity may be advantageous in overcoming OS, CS, and their undesirable consequences, with low dose efficacy and limited toxicity, compared to ARI or antioxidant alone.
AtıfScopus5WoS6OpenAlex5İncele - MakaleAçık Erişim2024Scopus SJRQ3The aroma profile of butter produceusing different starter cultures; [Aromatski profil maslaca proizvedenih korištenjem različitih starter kultura]
Şengül, Mustafa; Akgül, Halil İbrahim; Ürkek, Bayram
The aroma of fermented dairy products is greatly influenced by starter cultures and by the lactic acid bacteria strains that are used as starter cultures. Experimental butter samples were produced using no starter culture, by a commercial starter culture (Lactococcus lactis subsp. lactis, Lactococcus lactis subsp. cremoris, Lactococcus lactis subsp. lactis biovar. diacetylactis, Leuconostoc mesenteroides), by a prepared bacteria mix (Lactococcus lactis subsp. lactis EM1, Lactococcus lactis subsp. cremoris EM28, Lactococcus lactis subsp. lactis biovar. diacetylactis G49, Leuconostoc mesenteroides B3), and by a prepared bacteria mix fortified with Lactobacillus rhamnosus B19 (L. rhamnosus B19). The aroma profile of the butter samples was investigated using a gas chromatography mass spectometry method (GC-MS). A total of 92 components were determined in the butter samples, including acids (12), alcohols (20), aldehydes (9), alkanes (6), esters (8), ketones (19) and several other aroma compounds (18). The sample containing the prepared starter culture had the most detectable aroma components, while the lowest number of aromatic components were found in the sample without a starter culture. 2,3-butanedione (diacetyl) was not detected in the sample without a starter culture. 2-Butanone 3-hydroxy-(acetoin) content was the highest in the sample containing the commercial starter culture and the lowest in the sample without a starter culture.
AtıfScopus6WoS3OpenAlex6İncele - MakaleAçık Erişim2024Scopus SJRQ2Determinants of Ecological Footprint: A Quantile Regression Approach
Özcan, Kübra Akyol
Through the examination of the ecological consequences of human actions, policymakers are able to distinguish certain areas in which resource use can be increased and the generation of waste diminished. This study examines the effects of foreign direct investment, gross domestic product, industrialization, renewable energy consumption, and urban population on the ecological footprints in 131 countries between 1997 and 2020. The objective of this study is to establish a thorough understanding of the relationship between these variables and ecological footprints while considering temporal changes from economic and environmental aspects. The analysis of a substantial dataset encompassing many countries aims to uncover recurring patterns and trends that can provide valuable information for the formulation of policies and strategies pertaining to sustainable development on a global level. The study fills a significant gap in the knowledge on the ecological impact of different variables, providing a nuanced understanding of the interdependencies among these factors, thus guiding sustainable development strategies, and promoting global sustainability. The study utilizes quantile regression analysis, a nonparametric estimator, to estimate consistent coefficients. The statistical analysis reveals that FDI, urbanization, and GDP have statistically significant and positive effects on ecological footprints. Industrialization and renewable energy consumption show significant and negative relationships with ecological footprints. The findings of this study contribute to the understanding of the relationships among these variables and provide insight to inform policy and decision-making efforts focused on reducing ecological consequences and advancing sustainable development goals.
AtıfScopus16WoS13OpenAlex21İncele - MakaleYayıncıda açık erişim2024Scopus SJRQ2The ARK2N (C18ORF25) Genetic Variant Is Associated with Muscle Fiber Size and Strength Athlete Status
Çigirtas, Rukiye; Bulgay, Celal; Kazan, Hasan Hueseyin; Akman, Onur; Sporis, Goran; John, George; Yusupov, Rinat A.; Sultanov, Rinat I.; Zhelankin, Andrey V.; Semenova, Ekaterina A.
Background: Data on the genetic factors contributing to inter-individual variability in muscle fiber size are limited. Recent research has demonstrated that mice lacking the Arkadia (RNF111) N-terminal-like PKA signaling regulator 2N (Ark2n; also known as C18orf25) gene exhibit reduced muscle fiber size, contraction force, and exercise capacity, along with defects in calcium handling within fast-twitch muscle fibers. However, the role of the ARK2N gene in human muscle physiology, and particularly in athletic populations, remains poorly understood. The aim of this study was threefold: (a) to compare ARK2N gene expression between power and endurance athletes; (b) to analyze the relationship between ARK2N gene expression and muscle fiber composition; and (c) to investigate the association between the functional variant of the ARK2N gene, muscle fiber size, and sport-related phenotypes. Results: We found that ARK2N gene expression was significantly higher in power athletes compared to endurance athletes (p = 0.042) and was positively associated with the proportion of oxidative fast-twitch (type IIA) muscle fibers in untrained subjects (p = 0.017, adjusted for age and sex). Additionally, we observed that the ARK2N rs6507691 T allele, which predicts high ARK2N gene expression (p = 3.8 x 10-12), was associated with a greater cross-sectional area of fast-twitch muscle fibers in strength athletes (p = 0.015) and was over-represented in world-class strength athletes (38.6%; OR = 2.2, p = 0.023) and wrestlers (33.8%; OR = 1.8, p = 0.044) compared to controls (22.0%). Conclusions: In conclusion, ARK2N appears to be a gene specific to oxidative fast-twitch myofibers, with its functional variant being associated with muscle fiber size and strength-athlete status.
AtıfScopus8WoS7OpenAlex8İncele - MakaleAçık Erişim2024Scopus SJRQ1Simple and inexpensive microwave setup for industrial based applications: Quantification of flower honey adulteration as a case study
Hasar, Ugur C.; Hasar, Hafize; Ozturk, Hamdullah; Korkmaz, Huseyin; Kaya, Yunus; Ozkaya, Mehmet Akif; Ebrahimi, Amir; Barroso, Joaquim J.; Nayyeri, Vahid; Ramahi, Omar M.
A simple and inexpensive microwave measurement setup based on measurements of magnitudes of transmission properties ( | S 21 | dB \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}|S₂₁|_dB\end{document} ) is proposed for industrial-based microwave aquametry (moisture or water content) applications. An easy-to-apply calibration procedure based on normalization is implemented to eliminate systematic errors in the measurement system. As a case study, we applied this setup for the quantification of water-adulteration in flower honey. After validating this system by distilled water and pure flower honey measurements, | S 21 | dB \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}|S₂₁|_dB\end{document} measurements of the pure flower honey with various adulteration percentages ( delta \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}δ\end{document} ) up to 9% are conducted to examine the performance of the measurement setup for quantification of water adulteration. A multi-dimensional fitting procedure is implemented to predict delta \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}δ\end{document} using the proposed inexpensive microwave measurement setup. It is shown that it is possible to quantify an adulteration level with an accuracy better than -/+ 1 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}∓ 1\end{document} % by the proposed measurement setup and the applied multi-dimensional fitting procedure.
AtıfScopus12WoS10OpenAlex15İncele - Derleme MakaleAçık Erişim2024Scopus SJRQ1High pressure homogenization for preservation of liquid foods-Mechanisms, molecular modifications and recent developments
Pandiselvam, R.; Özaslan, Zeynep Tugba; Sahni, Prashant; Khanashyam, Anandu Chandra; Kutlu, Naciye; Yilmaz, Merve Silanur; Isleroglu, Hilal; Ramniwas, Seema; Rustagi, Sarvesh
High Pressure Homogenization (HPH) is emerging as a cutting-edge, non-thermal technology for liquid food preservation, offering significant advantages over conventional methods. Recent advances in HPH technology, particularly with the development of robust valves capable of withstanding pressures of 350-400 MPa, have opened new possibilities for the food industry. HPH not only extends the shelf life of liquid foods but also preserves nutritional value, improves homogeneity, reduces energy consumption, and minimizes the need for chemical preservatives. Its ability to inactivate microorganisms and enzymes while modifying bioactive components is particularly valuable for enhancing food safety and nutritional quality. Novel aspects of HPH include its efficiency in microbial and enzyme inactivation through cellular disruption, demonstrated in both lab and industrial settings, as well as its capacity to alter the functional properties of proteins, carbohydrates, and lipids. This results in improved stability, viscosity, and shelf life of various products. The versatility of HPH enables the development of novel food formulations that meet evolving consumer demands for safer, more nutritious options. This review critically examines the literature on HPH's application in liquid foods, focusing on its impact on enzymatic activity and bioactive components, while highlighting the parameters that influence microbial inactivation during HPH processing. The ongoing technological advancements in HPH present a promising future for revolutionizing food preservation practices.
AtıfScopus17WoS13OpenAlex21İncele - MakaleAçık Erişim2024Scopus SJRQ1The effect of high-intensity plyometric training on anaerobic performance parameters: a pilot study in U17 elite A league
Söyler, Mehmet; Zileli, Raif; Çingöz, Yunus Emre; Kilinçarslan, Gokmen; Kayantas, Idris; Altug, Tolga; Asan, Selim; Sahin, Musa; Gürkan, Alper Cenk
The aim of this study was to examine the effects of high-intensity plyometric training (HIPT) on some parameters in elite soccer players in the U17. Volunteer soccer players were randomly divided into two groups according to their positions: the regular training (RT) group (age: 16.71 +/- 0.47 years; stature: 163.46 +/- 3.31 cm; body weight: 61.04 +/- 1.59 kg) and the HIPT group (age: 16.64 +/- 0.50 years; stature: 165.60 +/- 3.03 cm; body weight: 59.76 +/- 1.92 kg), and each group included five defenders, five midfielders, and four attackers. While the RT group did only routine soccer training, the HIPT group performed high-intensity plyometric training three days a week in addition to routine soccer training. In the study, body weight, stature, sprint (10 m, 30 m, and 40 m), jump (standing long jump, right and left-limb triple hop) and 5-0-5 change of direction speed test measurements of the soccer players were taken. Skewness and Kurtosis values obtained from the pre-test and post-test measurements were calculated to test whether the normality assumption of the study was met. A mixed measure two-way ANOVA test was used to determine the difference between the pre-test and post-test. The significance was set asp < 0.05. The results indicated that 8-week high-intensity plyometric training provided more improvement in measured performance parameters than routine soccer training. As a result, when the data obtained is examined, it can be said that HIPT had better values in sprint, jump, and change of direction parameters, so plyometric training was more beneficial for anaerobic parameters than routine soccer training in children. It is recommended that the trainers make their plans considering these results.
AtıfScopus11WoS11OpenAlex10İncele - MakaleAçık Erişim2023Prioritising and selecting the railway routes planned in the Eastern Black Sea Region with the AHP and TOPSIS methods
Boz, Ediz; Türk, Ersin; Togan, Vedat
The construction of the railway, which is needed for the development of the Eastern Black Sea Region, is an issue that has been discussed and unresolved for about 110 years. The geomorphological structure of the region and the developments in the highway played a role in the delay of the railway construction. However, the developing technology in the railway, Turkey's being a part of the Iron Silk Road Project, and the agreements made with international connections have brought the railway construction to the region again. In the Environmental Plan (EP) approved and in force by the Ministry of Environment, Urbanization and Climate Change, four railway routes are planned to integrate the Eastern Black Sea region with the national/international railway network. These routes are; Samsun-Sarp, Trabzon-Erzincan, Of -Erzurum and Tirebolu-Bayburt. However, some of these routes are alternatives to each other and are not feasible and rational since the implementation of all planned routes requires great costs. The aim of this study is to develop a method for prioritizing and selecting the railway routes planned in the EP. Within the scope of this purpose, by using Analytical Hierarchy Process (AHP) and TOPSIS techniques, which are multi-criteria decision making methods, the routes were listed according to 4 criteria and 10 sub-criteria determined with the help of literature and expert team. As a result of the study; In both techniques, the order was the same and it was determined that the Samsun-Sarp railway was the most priority railway route. Trabzon-Erzincan came second, Of-Erzurum came third and Tirebolu-Bayburt came fourth.
AtıfWoS3OpenAlex3TR Dizin2
İncele - MakaleAçık Erişim2023Investigation of the relationship between NFKB1 polymorphisms and telomere length and apoptosis in patients with type-2 diabetes
Dirican, Ebubekir; Kaya, Yasemin
Purpose: Type 2 diabetes mellitus (T2DM) is a heterogeneous, chronic, and metabolic disease that affects a significant proportion of the global population. This study aimed to evaluate the effect of NFKB1-94 ATTG ins/del polymorphisms on the expression of apoptosis genes and telomere length (TL) in patients with T2DM compared with healthy individuals.Materials and Methods: Sixty-nine T2DM patients and sixty healthy people were enrolled in the study. DNA and RNA were isolated from the blood samples. NFKB1 genotypes were identified by Sanger sequencing. For TL analyses and to investigate the expression of the caspase-3, caspase-9, bax, and bcl2 genes, RT-PCR was utilized.Results: There was a significant difference between the NFKB1-94 ins/del genotype patients and the control group (OR:0.4792 (0.2345-1.011)). However, the distribution of other genotype/alleles (ins/ins and del/del) showed no difference between T2DM and control groups. The allelic frequency of NFKB1-94 ins/del was 0.455/0.235 for the T2DM group and 0.435/0.165 for the control group. An increase in the mRNA expression of caspase-3, caspase-9 and Bax genes was observed in the T2DM group compared with the healthy group, while a decrease in the Bcl2 gene was found in the T2DM group. TL in T2DM patients was shorter than in healthy individuals.Conclusion: NFKB1-94 ins/del polymorphisms show significant differences in T2DM patients. We observed that apoptosis was activated and TL was shortened in patients with T2DM. However, no relationship between NFKB1 polymorphisms and apoptosis and TL could not be determined.
- MakaleAçık Erişim2023Contributions to the Genus Mesiotelus Simon, 1897 in Turkey, with the Description of a New Species (Araneae: Liocranidae)
Demircan Aksan, Nurcan
In this study, a new species of the genus Mesiotelus Simon, 1897, Mesiotelus mersinensis sp. n., was described on the basis of a male from characteristic structures were presented. Besides, the species Mesiotelus scopensis Drensky, 1935 of this genus, which has a very poor distribution in Turkey, was recorded from a different locality. The current distribution in Turkey of species was shown on the map.
AtıfWoS1OpenAlex1İncele - MakaleAçık Erişim2023Scopus SJRQ1New RSM-FEM-Based Active Lateral Earth Thrust Coefficient Determination Method for Inverted T-Type Cantilever Retaining Walls Supporting Narrow Granular Backfill
Kamiloglu, Hakan Alper
This study was aimed to (1) investigate the failure surface mechanism occurring behind the wall supporting narrow backfill with experimental and numerical approaches; (2) determine the effect of internal friction angle (phi), friction (delta), heel length (beta), foundation thickness (alpha), backfill inclination (psi), and backfill width (theta) parameters on lateral earth thrust coefficients; and (3) derive finite-element analysis (FEM)-response surface method (RSM)-based lateral earth thrust coefficient equations for inverted T-type retaining walls supporting narrow backfill. The study was performed for granular backfill. A small-scale test was performed to investigate the failure surface mechanism in the narrow granular backfill. The particle image velocimetry method was employed to determine failure surface patterns for various heel lengths and backfill widths. Finite-element (FE) analyses were also performed to verify the experimental results. From the analyses, it was seen that two characteristic soil blocks formed behind the horizontally translated wall. Due to these soil blocks, the wall was divided into three characteristic regions. Lateral active earth thrust coefficients were derived for the regions. RSM was employed to derive FE-based lateral earth thrust coefficient estimation equations for each region. In this context, three design matrices were created, comprising 76 runs. In the design, parameters phi, delta, beta, alpha, psi, and theta were used as independent variables. A total of 76 FE analyses were performed for various parameter combinations. The results of the FE analyses were used as a response. From the statistical analyses, lateral active earth thrust estimation equations for narrow backfill were derived. The suggested equations were compared with the results of experimental, numerical, and analytical studies, and it was seen that the method gives reliable results. The effects of independent variables and their interactions on lateral earth pressure coefficients were examined.
AtıfWoS3OpenAlex3İncele - MakaleAçık Erişim2023STRONGLY HYPERBOLIC TYPE CONVEXITY AND SOME NEW INEQUALITIES
Kadakal, Huriye; Kadakal, Mahir
In this study, we introduce and study the concept of strongly hyperbolic type convexity functions and their some algebraic properties. We obtain Hermite-Hadamard type inequalities for the strongly hyperbolic type convex functions. After that, by using an identity, we get some inequalities for strongly hyperbolic type convex functions. In addition, we compare the results obtained with both Holder, Holder-Iscan inequalities and power-mean, improved power-mean integral inequalities.
AtıfWoS2OpenAlex2İncele - MakaleYalnız künye2023MULTIPLICATIVELY PREINVEX P-FUNCTIONS
Kadakal, Huriye; Kadakal, Mahir
In this study, using both Holder's integral inequality and Holder-Iccan integral inequality, some inequalities of Hermite Hadamard type obtained for multiplicatively preinvex P -functions are given. Afterwards, the result obtained with Holder-Iccan inequality has been shown to be better than that obtained with Holder's integral inequality.
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