Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Dertli, Enes(115)
- Kaya, Yunus(50)
- Ayata, Ümit(48)
- Şahin, Engin(48)
- İspirli, Hümeyra(46)
- Bayraktar, Bülent(42)
- Şenay, Volkan(41)
- Can, Zehra(39)
- Özen, Soner(37)
- Bayram, Sinan(35)
- Pat, Suat(35)
- Öztürk, Mesut(35)
- Ecem Bayram, Nesrin(34)
- Esmer, Yusuf(34)
- Battal, Fetullah(33)
- Artar, Musa(32)
- Öner, Erdal(32)
- Korkmaz, Şadan(31)
- Yilmaz, Mustafa Tahsin(31)
- Ertugrul, Mehmet(30)
- Mercan, Emin(30)
- Hasar, Ugur Cem(29)
- Kutlu, Naciye(28)
- Özdemir, Akın(27)
- Kul, Murat(26)
- Cuce, Erdem(25)
- Kamiloğlu, Aybike(25)
- Bayram, Ozkan(24)
- Sefali, Abdurrahman(24)
- Sert, Durmuş(24)
- Çolak, Murat(24)
- Ayazoglu, Rabil(22)
- Gıdık, Betül(22)
- Maden, Sedat(22)
- Ustabulut, Mete Yusuf(22)
- Uçurum, Metin(22)
- Akeren, Zahide(21)
- Dirican, Ebubekir(21)
- Kara, Yakup(21)
- Abdioglu, Murat(20)
Yayınlar
- MakaleAçık Erişim2022Scopus SJRQ1Easy-to-Implement Ultra-Thin, Wide-Band, and Multi-Functional Polarization Converter for K and Ka Band Applications
Coskun, Aykut; Hasar, Ugur Cem; Ozmen, Ahmet; Ertugrul, Mehmet
This article presents an ultrathin, broadband, and multipurpose polarization converter design utilizing an anisotropic metasurface for K and Ka band. The proposed polarization converter, which has a single layer F4B as a substrate material with hexagonal-shaped metallic solid structure along with hexagonal ring with diagonal splits on its front surface and a background (a completely metallic surface) on its back, works as not only a circular polarization converter but also a linear polarization to circular polarization (LP to CP) converter. Its polarization conversion rate (PCR) is more than 90% in the frequency range from 17.87 to 43.15 GHz, covering all of the K and Ka bands with a relative bandwidth of 83% under normal incidence case. For incidence angles up to 40°, PCR is observed to be greater than 75% in almost all of the K and Ka bands (except for the frequency range between 24.72 and 27.11 GHz). Furthermore, the proposed design has LP to CP in two different frequency bands, 16.23–16.74 GHz and 48.6–48.8 GHz. The proposed polarization converter, as advantages, is low cost, ultra thin, broadband, and facile, which can be useful in linear cross polarization conversion in K and Ka band applications.
AtıfScopus10WoS9OpenAlex10
İncele - MakaleAçık Erişim2022Scopus SJRQ2Pastinaca vanensis (Apiaceae), a new species from Turkey
Demir, Ibrahim; Sefali, Abdurrahman; Yapar, Yakup
Pastinaca vanensis is described as a new species from the Başkale district (Van-Turkey). Its diagnostic characteristics are discussed, and taxonomic comments are presented. P. vanensis is related to Pastinaca zozimoides but differs from this species in indumentum, petal color, and mericarp features. Data on ecology and the conservation status of the new species are also presented. A distribution map of the new and related species is provided.
- MakaleAçık Erişim2022Prospective primary school teachers' change in attitudes and anxiety profiles during their preparation program
Sarikaya, İsmail; Sökmen, Yavuz
The sensory characteristics of teachers and prospective teachers directly affect them and their teaching activities. It is important to examine in detail how the attitude and anxiety levels of prospective primary teachers towards the teaching profession change throughout the years they receive education. This study aimed to cross-sectionally and longitudinally examine whether the attitude and anxiety levels of prospective primary school teachers towards the teaching profession changed throughout their undergraduate education and determine the factors/experiences triggering this change in accordance with the qualitative data obtained. A cross-sectional study was carried out with the participation of 1085 prospective teachers. For the longitudinal study, quantitative and qualitative data were collected together from 57 prospective teachers over a period of four years. Attitude scale regarding teaching and occupational anxiety scale for prospective teachers were used for data collection. The results of both the cross-sectional and longitudinal studies showed that the attitude scores of the participants did not change in accordance with the grade level. However, it was determined that the anxiety scores of the participants decreased as the grade level increased. The results revealed that this change is statistically significant. The qualitative results revealed that internship practices and direct experiences had a great influence on this change.
AtıfOpenAlex1İncele - MakaleAçık Erişim2022Scopus SJRQ1Improvement of mechanical and transport properties of reactive powder concrete using graphene nanoplatelet and waste glass aggregate
Arslan, S.; Öksüzer, N.; Gökçe, H.S.
In this study, the use of graphene nanoplatelet (GNP) and waste glass aggregate (WGA) was investigated to improve the mechanical and transport properties of reactive powder concrete (RPC), which is an ultra-high strength concrete type. The co-addition of 0.14% GNP and 30% WGA resulted in a significant increase in the compressive strength of RPC from 192.9 to 258.9 MPa and flexural strength from 16.2 to 38.7 MPa. In the study, the most significant improvement (138.6%) was obtained for the flexural strength values of RPC. Considering the strength aspects, the relevant amounts of GNP and WGA enable production of RPC ensuring a conducted electrical charge of less than 100 Coulombs; that is, with negligible chloride ion permeability. Accordingly, the highest improvement (59.8%) after flexural strength was found for the resistance of the specimens against chloride ion penetrability. In conclusion, the findings of this study show that eco-efficient production of RPC with superior mechanical and durability characteristics can be achieved using GNP and WGA, with lower cement consumption per unit value of these studied characteristics, reaching 59%.
AtıfScopus31WoS26OpenAlex32İncele - MakaleYalnız künye2022INEQUALITIES FOR (α, m1, m2)-ARITHMETIC GEOMETRICALLY CONVEX FUNCTIONS VIA BY GAMMA AND INCOMPLETE GAMMA FUNCTIONS
Kadakal, Huriye
In this study, we introduce concepts of (α, m1, m2)-arithmetic geometrically (AG) convex functions and establish some Hermite-Hadamard type inequalities of these classes of functions via gamma and incomplete gamma function.
- MakaleYalnız künye2022Scopus SJRQ2Investigation of the Treatment of Olive Mill Wastewater by Electrooxidation
Kul, Sinan; Boncukcuoğlu, Recep; Ekmekyapar Torun, Fatma; Reçber, Züleyha; Sözüdoğru, Onur; Aladağ, Erdinç
The electrooxidation process, one of the advanced oxidation processes, is one of the effective treatment processes used in treating various industrial wastewaters. This study investigated the treatment of olive mill wastewater using the electrooxidation process. This study includes the effects of different experimental parameters on chemical oxygen demand and total phenol removal efficiencies in olive mill wastewater. Ti/IrO2/RuO2 mesh plates as anode material and Ti mesh plates as cathode material were used in the study. The effects of stirring rate, dilution factor, pH, type of support electrolyte, the concentration of support electrolyte, and current density on chemical oxygen demand and total phenol removal efficiencies were examined in the experiments using a batch reactor. The study found that the chemical oxygen demand and total phenol removal rates were 96.93% and 100% under optimum conditions, respectively. According to the treatment data obtained, it can be said that olive mill wastewater can be treated by the electrooxidation method and can be proposed as a pretreatment system before entering biological treatment.
AtıfScopus8WoS6OpenAlex8İncele - MakaleAçık Erişim2022Scopus SJRQ1The impact of ozone treatment on whey concentrate on the flow behaviour, functional and microbiological characteristics of whey powder
Sert, Durmuş; Mercan, Emin
The impact of ozone treatment (OT) for 0 (control) 30, 60, 90 and 120 min to whey concentrate (WC) on powder flow, physicochemical, functional, and microbiological characteristics of whey powders (WPs) was examined. OT decreased the cohesiveness of WC, whereas the firmness, consistency and index of viscosity were not affected. OT caused higher L∗ and b∗ values in WP and improved the solubility and foaming capacity, but decreased foaming stability and bulk density. OT increased the mean particle size of WP samples depending on the treatment time. Higher treatment time of OT resulted in a lower cohesion index. OT decreased caking ability of WP samples and increased flow stability. Compaction coefficient and cohesion index depending on increasing test speed, were generally reduced with higher OT. Overall, powder flow analyses revealed that OT of WC resulted in improved flow behaviour of WP. The microbial load of WP was reduced using OT.
AtıfScopus14WoS10OpenAlex16İncele - MakaleYalnız künye2022Scopus SJRQ2Application of artificial neural networks in the analysis of the continuous contact problem
Yaylacı, Ecren Uzun; Öner, Erdal; Yaylacı, Murat; Özdemir, Mehmet Emin; Abushattal, Ahmad; Birinci, Ahmet
This paper investigates the artificial neural network (ANN) to predict the dimensionless parameters for contact pressures and contact lengths under the rigid punch, the initial separation loads, and the initial separation distances of a contact problem. The problem consisted of two elastic infinitely layers (EL) loaded by means of a rigid cylindrical punch and resting on a half-infinite plane (HP). Firstly, the problem was formulated and solved theoretically using the Theory of Elasticity (ET). Secondly, the contact problem was extended based on the ANN. External load, the radius of punch, layer heights, and material properties were created by giving examples of different values used at the training and test stages of ANN. Finally, the accuracy of the trained neural networks for the case was tested using 134 new data, generated via ET solutions to determine the best network model. ANN results were compared with ET results, and well agreements were achieved.
AtıfScopus62WoS60OpenAlex13İncele - MakaleYalnız künye2022Scopus SJRQ1Performance of fly ash-blended Portland cement concrete developed by using fine or coarse recycled concrete aggregate
Şimşek, O.; Pourghadri Sefidehkhan, H.; Gökçe, H.S.
The recycling of concrete and industrial wastes in the production of new concrete structures has increased its share due to the growing environmental concerns of the world. In this study, the use of recycled concrete aggregate at various replacement amounts (0–100 %) was investigated to be fine or coarse aggregate sources instead of crushed natural aggregate to understand better its effects on the dimensional stability and durability aspects of fly ash-blended Portland cement concrete. In the presence of recycled concrete aggregate, fly ash was very important for eliminating possible mechanical losses of concrete at 90 days. The use of coarse recycled concrete aggregate resulted in better compressive strength values of concrete exposed to with and without wetting–drying and freezing-thawing cycles when compared to fine ones. While the free drying shrinkage of concrete increased at significant amounts (68 and 79 %) for fine and coarse recycled concrete aggregate, the restrained drying shrinkage crack widths were reduced up to by 13.5 %. In conclusion, it should be noted that the amount and size of recycled concrete aggregate need to be designed by considering the residual quality and dimensional stability of concrete, which exposes weathering actions in place.
AtıfScopus57WoS50OpenAlex54İncele - MakaleYalnız künye2022Scopus SJRQ2Organic acids and their derivatives: minor components of bee pollen, bee bread, royal jelly and bee venom
Çelik, Saffet; Gerçek, Yusuf Can; Özkök, Aslı; Ecem Bayram, Nesrin
This study aimed to determine the organic acid profiles of bee products such as royal jelly, bee venom, bee pollen and bee bread, as well as to verify the method employed in the study. For this purpose, royal jelly, bee venom, bee pollen and bee bread samples were obtained from different locations, and 55 individual organic acids were determined using the liquid chromatography technique coupled with tandem mass spectrometry (LC–MS/MS), and method verification was carried out. Moreover, principal component and hierarchical cluster analyses were performed to compare the organic acid content of bee products and evaluate the overall variation. According to the results, the order of the total organic acid profiles was determined as bee venom (4141 mg/kg-6260 mg/kg) > bee bread (736–990 mg/kg) > bee pollen (837–1503 mg/kg) > royal jelly (192–1947 mg/kg). Although citric acid (423–41,519 mg/kg) was dominantly detected in samples among the organic acids screened. It is thought that the results obtained will contribute to scientific studies carried out to determine the authenticity of bee products and their standardization.
AtıfScopus24WoS21OpenAlex26İncele - MakaleAçık Erişim2022Scopus SJRQ1Optimization of Ultrasonic Extraction of Nutraceutical and Pharmaceutical Compounds from Bee Pollen with Deep Eutectic Solvents Using Response Surface Methodology
Çelik, Saffet; Kutlu, Naciye; Gerçek, Yusuf Can; Bayram, Sinan; Pandiselvam, Ravi; Bayram, Nesrin Ecem
In recent years, there has been increasing interest in green extraction methods and green solvents due to their many advantages. In this study, the effects of an ultrasonic extraction method and deep eutectic solvents (DESs) on the extraction of different bioactive substances from bee pollen were investigated. In this regard, the effects of process variables such as the molar ratio of the DES (1, 1.5, and 2), sonication time (15, 30, and 45 min), and ultrasonic power (90, 135 and 180 W) on total individual amino acids, total individual organic acids, and total individual phenolic compounds were investigated by response surface methodology (RSM). The optimal conditions were found to be a molar ratio of 2, sonication time of 45 min, and ultrasonic power of 180 W (R2 = 0.84). Extracts obtained via the maceration method using ethanol as a solvent were evaluated as the control group. Compared with the control group, the total individual amino acid and total individual organic acid values were higher using DESs. In addition, compounds such as myricetin, kaempferol, and quercetin were extracted at higher concentrations using DESs compared to controls. The results obtained in antimicrobial activity tests showed that the DES groups had broad-spectrum antibacterial effects against all bacterial samples, without exception. However, in yeast-like fungus samples, this inhibition effect was negligibly low. This study is the first to evaluate the impact of DESs on the extraction of bioactive substances from bee pollen. The obtained results show that this innovative and green extraction technique/solvent (ultrasonic extraction/DES) can be used successfully to obtain important bioactive compounds from bee pollen.
AtıfScopus33WoS28OpenAlex36
İncele - MakaleAçık Erişim2022Scopus SJRQ1Emerging trends of online assessment systems in the emergency remote teaching period
Topuz, Arif Cem; Saka, Eda; Fatsa, Ömer Faruk; Kurşun, Engin
The COVID-19 pandemic caused many educational institutions in the world to switch to the distance education process, and this process was called "Emergency Remote Teaching". This urgent transition process has caused many problems in educational environments. One of the problems is the subject of measurement and evaluation. Along with the pandemic, many institutions have used various online assessment systems to make measurements and evaluations online, and researchers have conducted research on these online assessment systems. This research focus on the features of the online assessment systems and aims to examine the trends towards the prominent features of the online assessment systems in the Emergency Remote Teaching period. For this purpose, the prominent online assessment systems have been determined by systematically analyzing academic studies published in 2020, and answers have been sought to the following research questions: (1) which platforms they support, (2) which security features they have, and (3) what common features they have. Identifying trends in the characteristics of online assessment systems is expected to guide practitioners, decision-makers, researchers, and system developers in the process of selecting and/or developing an online assessment system for use in online measurement and evaluation.
AtıfScopus37WoS20OpenAlex45İncele - MakaleAçık Erişim2022Scopus SJRQ1Double adaptive power allocation strategy in electric vehicles with battery/supercapacitor hybrid energy storage system
Çorapsız, Muhammed Reşit; Kahveci, Hakan
This paper proposes a new energy management strategy (EMS) for electric vehicles (EVs) with battery/supercapacitor hybrid energy storage systems (HESS). Firstly, the battery/supercapacitor HESS configuration and obtaining the load current from the driving cycle are comprehensively explained. Secondly, fixed and adaptive frequency-based (AFB) EMS are discussed in detail. In the proposed method, the current demanded by the load is separated into low and high-frequency components with the help of an adaptive low-pass filter (A-LPF). In addition, adaptive battery current (ABC) is generated according to the supercapacitor (SC) state of charge (SoC), and a double adaptive power allocation strategy is performed. The proposed method is compared with the AFB-EMS for load currents, load powers, DC link voltages, filter cut-off frequencies, battery, and SC SoCs on the UDDS driving cycle. When the obtained results were evaluated together, it was observed that the proposed method completed the driving cycle with a higher battery SoC and realized the adaptive cut-off frequency in a narrower band.
AtıfScopus14WoS12OpenAlex14İncele - MakaleYalnız künye2022Scopus SJRQ2The effect of flours of different immature cereal grains on sourdough and sourdough bread: Microbiological, rheological, textural and sugar profiles
Alkay, Zühal; Yılmaz, Mustafa Tahsin; Can, Aslı Muslu; İspirli, Hümeyra; Dertli, Enes
In this study, the utilization of LAB (Lactiplantibacillus plantarum, Levilactobacillus brevis, Furfurilactobacillus rossiae, Weissella cibaria) cultures with selected flours of different immature cereal grains (wheat, barley, oat and rye) on sourdough and sourdough bread was investigated. In total, 16 different sourdough breads were produced and microbiological, pH, TTA and rheological properties of sourdoughs at 0, 8 and 24 h were determined. At the beginning of the fermentation, while sourdoughs showed elasticity, they showed viscoelastic properties after 24 h of fermentation. The sugar profile of cereal grains at the stage of milk formation and the sugar groups presented in EPSs isolated from sourdoughs were revealed by HPLC analysis. The sugar groups in sourdoughs were glucose, xylose and arabinose, while the sugars in the immature cereal grains were glucose, fructose and mannose. The highest EPS production level (1882.69 ± 8.16) was observed in immature barley flour and Lpb. plantarum containing sourdough and all sourdoughs were found to contain glucan type EPSs. It was observed that the amount of EPS produced by the related species differed significantly under different grain conditions. Besides, it was observed that the sourdough breads produced were harder than the control bread. Novelty Impact Statement: Wheat, barley, oat and rye immature grains and four distinct LAB strains were used during sourdough fermentation. Immature grain type and LAB strain used were determinants for in situ exopolysaccharide (EPS) production. Viscoelastic properties of sourdough and textural properties of sourdough bread were affected by grains and LAB strain utilized.
AtıfScopus5WoS2İncele - MakaleYalnız künye2022Scopus SJRQ1Powder flow behaviour, functional characteristics and microstructure of whole milk powder produced from cow and buffalo milk mixtures
Sert, Durmuş; Mercan, Emin; Kılınç, Mehmet
The effects of cow and buffalo milk mixtures on powder flow behaviour, functional characteristics and microstructure of whole milk powder was investigated. Milk powder was produced from 100% cow milk (G1), 100% buffalo milk (G2), 75% cow/25% buffalo milk (G3), 50% cow/50% buffalo milk (G4) and 25% cow/75% buffalo milk (G5). A higher proportion of buffalo milk increased the hydroxymethylfurfural, thiobarbituric acid reactive substances and free fatty acid contents in powders, but decreased dispersibility and wettability. The lowest and highest mean particle size values were obtained in G3 and G2 samples. Milk powder containing a higher level of buffalo milk increased caking ability and compaction coefficients of milk powder. All samples had remarkably cohesive characteristics. A higher proportion of cow milk can improve the flow behaviour of milk powder containing cow and buffalo milk mixtures in terms of caking, cohesion, and powder speed flow dependency.
AtıfScopus11WoS7OpenAlex8İncele - MakaleYalnız künye2022Scopus SJRQ3Optimization of Ultrasound Extraction of Phenolic Compounds from Tarragon (Artemisia dracunculus L.) Using Box–Behnken Design
Kutlu, Naciye; Kamiloglu, Aybike; Elbir, Tugba
In this study, ultrasound extraction of bioactive compounds from tarragon was examined as a sustainable technology. Pure water, which is a green solvent, was used as solvent. Box–Behnken was used in the experimental design, and ultrasonic power, extraction time and solvent-to-sample ratio were determined to be independent variables. The physicochemical properties were determined by physical (color, pH, Brix) and chemical analyses (antioxidant activity, total flavonoid and total phenolic compound (TPC)) in the extracts obtained under different conditions. Optimum conditions were found to be 73.9% ultrasonic power, 43.2 min sonication time and 10 mL/g solvent-to-sample ratio. The composite desirability (R2) of optimum conditions was 99.3% after optimization. Since high efficiency was obtained in a short time with ultrasound extraction, it was found to be quite good in terms of energy savings. That is, the highest TPC was obtained with a sonication time of 45 min with this method, while similar TPC in the control group (maceration) was obtained in 24 h. In the optimum conditions, extraction with other green solvents (ethanol and deep eutectic solvent—DES) was carried out and bioactive compound yields were compared. For different solvents compared under optimum conditions, ethanol gave higher yields in terms of TPC, while higher yields were obtained in samples using water as solvent for some antioxidant activity values. The results obtained with DES were not as high as expected, and this resulted in the conclusion that a hydrogen bond donor is not suitable for obtaining bioactive compounds from tarragon.
AtıfScopus9WoS9OpenAlex9İncele - MakaleAçık Erişim2022Scopus SJRQ1Optimum sizing design of steel frame structures through maximum energy dissipation of friction dampers under seismic excitations
Artar, Musa; Carbas, Serdar
This paper focuses on optimum sizing design of steel frame structures equipped with friction dampers (FDs) in order to prevent the vulnerable effect of an earthquake. The fundamental concept is to maximize the energy dissipation of implemented FDs under different seismic excitations. The FDs utilized as passive energy dissipation devices in a steel structure increase the energy dissipation capacity of the structure by decreasing the seismic demand during an earthquake. In this context, the Pall friction dampers (PFDs) are implemented as diagonal damped brace members in investigated structures. Three different earthquake records (Kobe, Kocaeli-Duzce, Erzincan) are utilized to acquire nonlinear dynamic responses of the steel frame structures through time-history analyses. The open application programming interface (OAPI) functions are used to integrate a finite element modelling based structural analysis program, SAP2000, with a design optimization algorithm encoded in MATLAB for achieving the exact structural behaviours by synchronously data transferring. As an optimizer, one of the recent nature-inspired metaheuristic techniques, so-called Grey Wolf (GW) algorithm is used. Initially, under effect of seismic excitations, the steel frame structures are optimally sized for attaining minimum design weights without implementing the PFD elements by subjecting only strength, displacement, drift, and geometric structural design constraints taken from AISC-LRFD practice code provisions. Afterward, in order for optimally modelling the PFD elements, the frames are equipped with PFDs to calculate optimum yield strengths that is defined as slip load of a PFD. To do so, the GW algorithm ensures the maximizing of the dissipated energy and controls the yield strengths between the stories since the shear force due to the earthquake increases towards the base of the structure. Eventually, the provisions-based sizing design optimizations of the steel frame structures equipped with optimally modelled PFD elements are conducted under seismic excitations for conclusive evaluations.
AtıfScopus21WoS18OpenAlex20İncele - MakaleYayıncıda açık erişim2022Scopus SJRQ2Evaluation of photon interaction parameters of Anti-HIV drugs
Akbaba, Uğur; Şakar, Erdem; Abu Al-Sayyed, Mohammed Ibrahim; Alim, Bünyamin; Özpolat, Özgür Fırat
Medical treatment inevitably exposes individuals to radiation, including those taking drugs used to treat and prevent human immunodeficiency virus (HIV). Motivated by this, we investigated the radiation interaction properties of several HIV drugs to determine the interaction parameters, mass attenuation coefficient (MAC), atomic cross section (ACS), electronic cross section (ECS), effective atomic numbers (Zeff), and effective electron density (Neff). We calculated the values using the Phy-X/PSD software in the range of 0.015–15 MeV. Additionally, we calculated the exposure build-up factor (EBF), and energy absorption build-up factor (EABF) values of the drugs up to 40 mean free path (MFP) using the geometric progression (G-P) method. From our findings, we determined that Combivir, with its relatively high heavy element content, had the highest radiation attenuation capacity, whereas the probability of Lopinavir interacting with photons was the lowest compared with the other drugs. The results of the EBF and EABF parameters, including the scattering effects, ordered the drugs opposite to the primary interaction parameters such as MAC, ACS, ECS, and Zeff. These findings can guide the treatment process of HIV-positive patients and inform HIV prevention practices conducted alongside radiotherapy, as the interaction between radiation and a drug may cause deterioration in the drug's structure.
AtıfScopus9WoS8OpenAlex12İncele - MakaleAçık Erişim2022Scopus SJRQ1Charity Social Media Marketing and Its Influence on Charity Brand Image, Brand Trust, and Donation Intention
Bilgin, Yusuf; Kethüda, Önder
This study aims to identify the outline of charity social media marketing (SMM) and to determine to what extent it influences the charity brand image, brand trust, and donation intention. The data were gathered from followers of internationally operating Turk charities on social media. The theoretical model and hypotheses were tested by using structural equation modeling. Charity SMM is composed of awareness, interaction, timeliness, informativeness, customization, and advertisement dimensions. Awareness is the only dimension of SMM that has a significant direct influence on donation intention. Timeliness, informativeness, and advertisement significantly influence charity brand image, whereas brand trust is influenced by informativeness and customization. Besides, Charity SMM, as a whole, influences donation intention both directly and indirectly through brand image and brand trust. Therefore, charity brand image and brand trust are crucial for charities to promote donation intention through SMM. Therefore, charities are strongly recommended to focus primarily on developing their brand image and gaining trust in current and prospective donors.
AtıfScopus63WoS49OpenAlex69İncele - MakaleYalnız künye2022Scopus SJRQ3Gram-scale synthesis of (S)-1-(thiophen-2-yl)ethanol in high enantiomeric purity under Enterococcus faecium BY48 biocatalysts
Şahin, Engin
Sulfur-containing chiral heterocyclic secondary alcohols are relevant intermediates in the preparation of enantiomerically pure compounds endowed with biological activity. In this report, we evaluated the reductive potential of different lactic acid bacteria as whole-cell biocatalysts of the enantioselective reduction of 1-(thiophen-2-yl)ethanone (1). Enterococcus faecium BY48, isolated from boza, a cereal-based fermented beverage, was found to be the best biocatalyst in our initial investigations. Using whole-cell preparations of E. faecium BY48, we then systematically analyzed the reaction parameters (pH, incubation period, agitation speed, and temperature) to optimize the yield, the enantiomeric excess (e. e.), and the conversion leading to (S)-1-(thiophen-2-yl)ethanol [(S)-2]. The target derivative, which is a precursor in the synthesis of biologically active chiral compounds, was obtained in enantiomerically pure form, gram-scale amounts, and high yield. This is also the first report that the manufacture of (S)-2 in excellent conversion, yield, enantiopure form, and gram scale used whole-cell biocatalyst. This whole-cell E. faecium BY48 biocatalyzed reaction is a clean, environmentally friendly, and cost-effective process, representing a valuable alternative to chemical catalysis or previously reported biocatalytic procedures in the preparation of (S)-2.
AtıfScopus3WoS3OpenAlex5İncele