Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Dertli, Enes(114)
- Kaya, Yunus(48)
- Şahin, Engin(48)
- İspirli, Hümeyra(47)
- Özen, Soner(38)
- Şenay, Volkan(37)
- Pat, Suat(36)
- Kutlu, Naciye(32)
- Artar, Musa(31)
- Can, Zehra(31)
- Korkmaz, Şadan(31)
- Yilmaz, Mustafa Tahsin(31)
- Öner, Erdal(31)
- Bayram, Sinan(30)
- Cuce, Erdem(30)
- Ertugrul, Mehmet(29)
- Hasar, Ugur Cem(29)
- Ecem Bayram, Nesrin(28)
- Mercan, Emin(28)
- Ayata, Ümit(27)
- Bayraktar, Bülent(27)
- Çolak, Murat(23)
- Özdemir, Akın(23)
- Ayazoglu, Rabil(22)
- Cuce, Pinar Mert(22)
- Sert, Durmuş(22)
- Bayram, Ozkan(21)
- Kamiloğlu, Aybike(21)
- Dirican, Ebubekir(20)
- Kadakal, Mahir(20)
- Abdioglu, Murat(19)
- Birinci, Ahmet(19)
- Tozlu, Alperen(19)
- Gerçek, Yusuf Can(18)
- Taylan, Osman(18)
- Cinar, Mehmet(17)
- Gul, Volkan(16)
- Hasar, Ugur C.(16)
- Kadakal, Huriye(16)
- Kara, Yakup(16)
Yayınlar
- MakaleYalnız künye2026Scopus SJRQ4CORRELATION BETWEEN THE CHEMICAL COMPOSITION OF WOOD AND THE INCREASING OF ITS CALORIFIC VALUE THROUGH HEAT TREATMENT; [CORRELAÇÃO ENTRE A COMPOSIÇÃO QUÍMICA DA MADEIRA E O AUMENTO DO PODER CALORÍFICO ATRAVÉS DO TRATAMENTO TÉRMICO]; [CORRELACIÓN ENTRE LA COMPOSICIÓN QUÍMICA DE LA MADERA Y EL AUMENTO DE SU PODER CALORÍFICO MEDIANTE TRATAMIENTO TÉRMICO]
Domingos, Idalina; Ferreira, Miguel; Ferreira, José; Dulyanska, Yuliya; Ayata, Umit; Esteves, Bruno
Introduction: The greatest importance of biomass lies in its Higher Heating Value (HHV), when considered for energy production. The calorific value is significantly affected by the changes in the chemical composition of the wood that occur during heat treatment. Objective: To understand the effect of heat treatment on the calorific value of the chemical constituents of two hardwoods: Sapelli and chestnut, and two softwoods: Scots pine and Siberian pine. Methods: The calorific value was determined by a Parr calorimeter – model 6400. The content of extractives was determined by successive Soxhlet extraction using about 3 g of each sample and 150 ml of dichloromethane, ethanol, and water as solvents. The extractives content was determined in accordance with TAPPI 204, and insoluble lignin by the Klason method Tappi T 222 om-02. For the determination of holocellulose, the acid chlorite method was used. Results: The calorific value of untreated wood ranged from 18.98 MJ/kg for chestnut to 20.35 MJ/kg for Siberian pine. Heat treatment resulted in an increase in the calorific value for most of the wood samples studied. Conclusion: The rise in HHV observed during heat treatment in softwoods and hardwoods is mainly due to the increase in lignin content, although dichloromethane extractives also play an important role.
- MakaleAçık Erişim2026Scopus SJRQ1The Effect of Mindfulness Practices on Positive Thinking and Stress Coping Behaviors of Earthquake Survivor Nursing Students: A Nonrandomized Controlled Study
Bal, Betul; Kaba, Nagihan Koroğlu
Purpose: This study was conducted to reveal the effect of mindfulness practices on nursing students’ stress-coping behaviors and positive thinking skills. Method: This was a two-group parallel nonrandomized study. Mindfulness practices were applied to the students in the experimental group. Data were collected using research tools (Personal Information Form, Positive Thinking Skills Scale, and Stress Coping Behaviors Scale for Nursing Students) as pre- and posttests. Findings: After the intervention, there was no significant difference between the two groups in the posttest scores of positive thinking skills (t = 0.624; p = .541) and stress coping behaviors of staying optimistic (t = −0.957; p = .345), transfer (t = −2.028; p = .050), problem-solving (t = −0.663; p = .512), and avoidance (U = 132; p = .230). Conclusions: Mindfulness practices are ineffective in improving earthquake survivor nursing students’ coping behaviors and positive thinking skills.
- MakaleAçık Erişim2026Scopus SJRQ3Financial Management of Traditional and Complementary Medicine in Türkiye Public Hospitals: A Policy Analysis of Pricing, Accounting, and Performance Incentives
Kılınç, Mehmet
This article presents a policy analysis of the financial management of Traditional and Complementary Medicine (T&CM) practices in public hospitals in Türkiye, with a focus on the intersection of pricing, accounting, and performance-based supplementary payment systems. While integrating T&CM into the modern healthcare system expands treatment options, it introduces significant administrative challenges. In recent years, the presentation of T&CM applications in public hospitals in Türkiye has become widespread. However, this expansion has raised critical questions, such as how these services will be charged and how the revenue generated will be accounted for. In this context, the extent to which current pricing policies support the sustainability of T&CM services is discussed. Adopting a descriptive policy analysis approach supported by analytical simulations, this study assesses the adequacy of current pricing policies. The findings reveal a systemic “performance paradox”: although time-intensive, T&CM procedures yield significantly lower performance scores per hour than standard outpatient services, creating a structural disincentive for physicians. Furthermore, the lack of transparency in cost-center accounting complicates the financial sustainability of these units. The study concludes by offering tiered policy recommendations—ranging from low-effort coefficient adjustments to high-effort payment model reforms—to align financial incentives with the strategic goal of integrating T&CM into the public health system.
- MakaleAçık Erişim2026Scopus SJRQ3The relationship between cultural tourism and transportation: A global perspective
Durmuş, İbrahim
The importance of tourism and cultural values for countries, regions, or areas is increasing day by day. Cultural tourism includes many activities with a wide scope. Transportation, on the other hand, is a factor that directs tourists' choices in terms of tourism, providing access to the areas they have visited or will visit. The research aims to reveal the factors affecting the relationship between cultural tourism and transportation. For this purpose, the focus is on cultural tourism and transportation research in the WoS database. The bibliometric analysis method was used in the application. Important inferences were obtained by evaluating 433 studies in the literature. As a result of the analysis, authors who have conducted intensive research on the subject, publication production amounts, efficiencies, organizations, citations, highlighted keywords, changes over time, trends, co-occurrence networks, thematic maps, and thematic developments are included. In their research, the authors frequently emphasized the words tourism, sustainable tourism, development, transportation, China, cultural tourism, rural tourism, sustainable development, accessibility, and sustainable. The results reveal that sustainability and accessibility are effective factors in cultural tourism and transportation. The study shows that in the network of relationships, tourism, heritage, accessibility, transport, cultural tourism, management, and cultural heritage have strong connections. The findings indicate that in the relationship between cultural tourism and transportation, accessibility, management mechanisms, and cultural heritage values are highly influential. Regarding centrality and density, rural tourism, tourism development, sustainable and ecological tourism, Mexico, rural development, colonialism, competitiveness, Istanbul, and renewable energy demonstrate strong relationships. These results show that rural development, competitiveness, and colonialism play a significant role in the relationship between cultural tourism and transportation. Regarding Türkiye, Istanbul's central and dense network of relationships has been influenced by its accessible location and tourism potential. The results provide a unique and different perspective on the literature.
- MakaleAçık Erişim2026Scopus SJRQ1The effect of cognitive strategy instruction enriched with active learning techniques on word problem-solving skills of students with learning disabilities
Filiz, Tunahan
This study aimed to investigate the effectiveness of cognitive strategy instruction (CSI) enriched with active learning (AL) techniques in teaching word problem solving to primary school students with learning disabilities, as well as to examine the overall instructional process. Word problem solving is the process of using contextual information from real-life or fictional situations to develop mathematical solutions. The research was designed with an embedded mixed-method model. The quantitative phase included 30 third-grade students with learning disabilities, while the qualitative phase involved six randomly selected students from the experimental group. Quantitative analyses revealed that students in the experimental group showed significantly higher achievement in problem-solving tests, indicating the positive impact of CSI enriched with AL techniques. Qualitative findings highlighted increased class participation, enhanced collaboration, and more positive attitudes toward mathematics. Furthermore, teacher and peer interactions supported the problem-solving process, and the use of tools promoting mathematical thinking strengthened performance. The results demonstrated that CSI enriched with AL techniques encouraged strategic thinking and the generation of alternative solutions in word problem solving. The study, limited to three learning outcomes within the third-grade mathematics curriculum in Turkey, suggests that teachers should adapt and implement such instructional approaches across other mathematical domains, given the students’ positive experiences and outcomes.
- MakaleAçık Erişim2026Scopus SJRQ1Ni- and Co-doped TiO2nanofibers for enhanced antibacterial and antibiofilm activities, and mechanistic insights
Özcan, Tuğçe; Çekceoğlu, İlknur Aksoy; Öner, Erkan; Ozel, Sultan Suleyman; Sarılmaz, Adem; Aslan, Emre; Özel, Faruk; Patır, İmren Hatay
Nowadays, with the growing need for alternative antibacterial materials for the treatment of bacterial infections, TiO2 with antibacterial properties has attracted attention as a potential antibacterial agent. Ni-TiO2 and Co-TiO2 nanofibers (NFs) were synthesized via an electrospinning process. The antibacterial activities of these NFs against S. aureus and E. coli were evaluated under UV-light illumination using optical density measurements. Co-TiO2 exhibited superior antibacterial activity against both S. aureus and E. coli under UV-light irradiation. The antibacterial mechanism was further investigated through a glutathione (GSH) oxidation assay and morphological analysis using scanning electron microscopy (SEM). Hydrophilicity was evaluated by contact angle measurement. The antibiofilm activities of TiO2, Ni-TiO2, and Co-TiO2 NFs were investigated with respect to E. coli and S. aureus biofilms. Ni-TiO2 and Co-TiO2 demonstrated more effective antibiofilm activities than bare TiO2. Under UV-light irradiation, the biofilm inhibition efficacy was increased for both Ni-TiO2 and Co-TiO2 NFs while Co-TiO2 NFs were found to have the greater antibiofilm performance. Additionally, in silico analysis was conducted to explore the molecular interactions of the NFs with S. aureus Immunoglobulin-Binding B Domain (PDB ID: 1BDD) and FimH lectin protein of E. coli (PDB ID: 4XO8). Co-TiO2 exhibited stronger binding to S. aureus, while TiO2 showed stronger binding to E. coli. This journal is
- MakaleAçık Erişim2026Scopus SJRQ1Permittivity extraction of sandy soils through uncalibrated and thickness-independent meniscus-free measurements using a hollow coaxial line
Hasar, Ugur C.; Korkmaz, Huseyin; Kaya, Yunus
Measurement techniques for accurate moisture level determination of various soil conditions are becoming popular in recent studies. Microwave-driven techniques, as positioned into indirect methods, could be tailored for precise and real-time detection of soil moisture. However, improper implementation of calibration techniques or usage of imperfect calibration standards required for precise measurements by these techniques presents a challenging limitation for their widespread usage. Besides, meniscus formation on top of soil samples with a sufficient moisture level could adversely influence the performance of these techniques. In this study, we present a microwave extraction method for eliminating the requirement of a formal calibration procedure and additionally removing the effect of meniscus on measurements through relative measurements of sandy soil samples while maintaining accurate permittivity extraction with no information of sample thickness. To achieve our goal, a mathematical framework unifying wave-cascading matrix and state-transition matrix presentations is proposed for permittivity determination from three measurement configurations (empty line, the (sandy) soil sample sandwiched between two identical plugs, and a shifted version of this plug-sample-plug configuration) and their inverses implemented by port switching operation. The proposed method is first validated by permittivity measurements of two liquid samples (distilled water and methanol). Then, permittivity measurements of two sandy soil samples (having more than 90% sand content) were conducted using Type-N-to-EIA 1-5/8” coaxial lines (with no universal calibration standard) over 0.05 GHz–3.0 GHz. From these measurements, it is noted that our meniscus-free method determines permittivity with a maximum absolute difference of 3.4% (evaluated from five independent measurements) while another similar method, suffering from meniscus presence, extracts permittivity with a maximum absolute difference of 4.0%. This indicates a clear advantage of our method for measurements of sandy soil samples having meniscus formation. We then utilized to construct a calibration curve, compared with other calibration curves using by other methods, allowing prediction of moisture volume content () of the tested sandy soil samples from measured permittivity data whose conformity analysis implemented by the three-pole Debye model and the Mironov-Fomin model. It is observed that this calibration curve could be utilized to predict within margin from measured permittivity data.
- MakaleYalnız künye2026Scopus SJRQ2Depth-dependent predictability of soil temperature under Mediterranean climatic conditions: a frequency-based perspective
Guleryuz, Didem; Yıldırım, Ümit; Güler, Cüneyt
Soil-temperature predictability is inherently depth-dependent because atmospheric forcing is progressively attenuated and transformed into smoother, lower-frequency thermal dynamics with increasing depth. Under Mediterranean climatic conditions, where pronounced seasonality and strong surface forcing coexist, this depth-dependent transformation provides an informative basis for evaluating model behaviour. This study examines soil-temperature prediction at depths of 5, 10, 20, 50, and 100 cm using a multivariate dataset comprising 5,285 retained daily observations from the Mersin meteorological station on Türkiye’s eastern Mediterranean coast. Precipitation, air temperature, relative humidity, wind speed, and evaporation were used as predictors. Support vector regression, random forest, and LightGBM were evaluated using R², RMSE, and MAE. All three models performed strongly in the near-surface layers, with test R² values ranging from 0.948 to 0.954 at depths of 5–20 cm. Predictive performance declined with increasing depth as short-period variability weakened and the thermal signal became smoother and more seasonally structured. RF and LightGBM showed a greater numerical decline at 50–100 cm, whereas SVR achieved test R² values of 0.923 at 50 cm and 0.847 at 100 cm; however, inter-model differences remained modest and were interpreted descriptively. Lomb–Scargle spectral analysis, applied using the actual observation dates, indicated that short-period variability became relatively less pronounced with depth while seasonal-scale and low-frequency components remained prominent. Overall, the findings suggest that soil-temperature prediction should be interpreted in relation to depth-dependent temporal signal characteristics rather than as a search for a universally superior algorithm.
- MakaleAçık Erişim2026Scopus SJRQ2Investigation of the levitation and drag force parameters of the electrodynamic maglev based on Halbach array of HTS bulks on aluminium rail
Ozturk, U.Kemal; Yıldız, Ali Suat; Abdioglu, Murat
This study aims to investigate the performance parameters of high-temperature superconducting (HTS) bulks and permanent magnets (PMs) as magnetic field sources in electrodynamic suspension (EDS) systems, with the goal of enhancing the currently low magnetic lift force and reducing the high drag force in such systems. A numerical analysis is conducted on an EDS system utilizing Halbach arrays of HTS and PM bulks. The H-formulation within the Partial Differential Equation (PDE) module is employed to simulate the flux-trapping performance of the HTS bulks, with results verified by experimental data from the literature. The lift and drag forces between the arrays and an aluminium rail are investigated using the Rotating Machinery-Magnetic module of COMSOL. It is observed that increasing the width of the central sample in the array results in a higher peak value of the vertical magnetic flux density and a broader peak profile, indicating a more extended effective magnetic field region across the rail surface. The HTS-based system exhibits significantly higher lift force and loading capacity compared to its PM-based counterpart. Specifically, a Halbach array composed of three HTS bulks (10 mm, 70 mm, 10 mm widths; HTS#10-70-10) achieves a better lift force representing a 211.5 % increase over the PM array. Furthermore, the lift-to-drag ratio (LDR) of the HTS array improves by 17.2 %. The results indicate that the HTS arrays offer superior performance in terms of both lift force and energy efficiency, highlighting their potential for enhancing the applicability of HTS-EDS systems in real-scale applications. This study features the advantages of HTS-based systems in achieving higher loading capacities and more efficient operation conditions compared to the PM arrays.
AtıfScopus1WoS1OpenAlex1
İncele - MakaleYalnız künye2026Scopus SJRQ2Effects of Graphite Incorporation and Annealing on the Structural, Tribological, and Functional Properties of Electroless Ni-B Coatings
Bülbül, Ferhat; Kara, Adem; Bülbül, Leman Elif; Güneş, Kübra
This study explores the synergistic effects of graphite nanoparticles (0.1 wt.%) and thermal annealing (100–600°C) on electroless Ni-B coatings for AISI 4140 steel. Graphite-enabled multifunctional performance—crystallization control, friction reduction, and antibacterial activity—are unlike conventional Ni-B systems. XRD showed amorphous-to-crystalline (Ni3B/Ni2B) transformation, with graphite acting as a nucleation agent below 300°C before degrading at 600°C. The 300°C-annealed composite achieved optimal properties: 0.2 friction coefficient (75% lower than uncoated steel), 60% higher wear resistance, and hardness of 777 HV (+ 3.6% over as-deposited), attributed to graphite lubrication and nanocrystalline Ni3B formation. Antibacterial tests revealed a 3.4-mm inhibition zone against E. coli, though efficacy declined at higher temperatures due to graphite oxidation. All composites maintained superhydrophilicity (contact angle ≈ 0°) without mechanical compromise. By correlating annealing temperature with microstructure, this work provides a design framework for Ni-B/graphite coatings combining low friction (μ = 0.2), high hardness (785 HV), and antibacterial functionality—addressing critical needs for wear-resistant, hygienic surfaces in biomedical and industrial applications.
AtıfScopus1WoS1İncele - Derleme MakaleYalnız künye2026Scopus SJRQ4Touching relief: A complementary path to easing rheumatoid arthritis pain
Kalyoncuo, Servet
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation, leading to pain, joint stiffness, and functional impairment. Despite advances in pharmacological treatments, including disease-modifying antirheumatic drugs (DMARDs) and biologic agents, many patients continue to experience residual symptoms that negatively affect quality of life. This review aims to evaluate the potential role of massage therapy as a complementary approach in the management of RA, with a focus on its clinical effects and proposed mechanisms. A structured literature search was conducted in Medline/PubMed, Scopus, and the Directory of Open Access Journals (DOAJ) for studies published up to March 1, 2025. Studies were considered if they included individuals diagnosed with RA, evaluated any form of massage therapy (e.g., Swedish massage, aromatherapy massage, reflexology), and reported clinical or patient-reported outcomes. Both randomized controlled trials and quasi-experimental studies were included, while studies involving non-RA populations or insufficient methodological detail were excluded. However, this review was not designed as a fully systematic review and may be subject to selection bias. The available evidence suggests that massage therapy may be associated with improvements in pain, joint mobility, and patient-reported outcomes in individuals with RA. However, the overall strength of evidence is limited by methodological concerns, including small sample sizes, heterogeneity in intervention protocols, and the frequent lack of appropriate control groups. While some studies report reductions in inflammatory biomarkers such as interleukin-6 (IL-6) and C-reactive protein (CRP), these findings are based on limited evidence and should be interpreted cautiously, particularly in studies where massage therapy is combined with other interventions. Massage therapy may also contribute to psychological well-being by reducing stress and improving overall mental health. Evidence derived from non-RA populations was considered only as supportive background and was not central to the conclusions of this review. Additionally, the potential for publication bias should be acknowledged, as studies with positive findings are more likely to be published. The integration of massage therapy into RA management may benefit from nurse-led approaches; however, variability in practitioner training and the lack of standardized intervention protocols remain important challenges. Future research should prioritize well-designed, adequately powered randomized controlled trials focusing specifically on RA populations, with standardized massage interventions and clearly defined outcome measures.
- MakaleYayıncıda açık erişim2026Scopus SJRQ3Investigation of Fe and Mn Effects on the Fluidity Behavior of A356 Aluminum Alloys
Çolak, M.; Alkan, N.; Kutsal, Ü.
The fluidity behavior of Al–Si casting alloys is strongly influenced by impurity elements and intermetallic phase formation during solidification. In particular, iron (Fe) reduces melt fluidity by forming brittle Fe-rich intermetallics, whereas manganese (Mn) can mitigate this effect by modifying intermetallic morphology. In this study, secondary A356 aluminum alloys were produced with Fe contents of 0.10, 0.15, and 0.20 wt.% and nominal Mn additions of 0.05, 0.10, and 0.20 wt.% to investigate their combined effect on fluidity behavior. Melt quality was assessed using reduced pressure testing and density index measurements to ensure consistent casting conditions. Fluidity tests were conducted using spiral and eight-channel molds with section thicknesses ranging from 0.5 to 8 mm. To enable quantitative comparison across different section geometries, a Fluidity Index (FI) was defined based on section-normalized flow lengths. The results show that increasing Fe content generally reduces fluidity, while Mn additions significantly improve melt flow, with the most pronounced enhancement observed at 0.20 wt.% Mn. Thinner sections were found to be more sensitive to Fe-related flow restriction, whereas wider channels exhibited improved flow behavior. These findings demonstrate that appropriate Mn additions can effectively stabilize fluidity in secondary A356 alloys and provide practical guidelines for alloy control in recycled aluminum casting applications.
- MakaleAçık Erişim2026Scopus SJRQ1Screening-based low energy availability risk, disordered eating risk, and their co-occurrence among female volleyball players: a cross-sectional study
André, Hülya; Sarışık, Derya Çetin; Özçelik, Arda
Low energy availability (LEA) and disordered eating (DE) are important health concerns in female athletes, yet their occurrence and co-occurrence in team-sport contexts, particularly volleyball, remain underexplored. This cross-sectional online survey study examined the proportions of athletes classified as being at risk of LEA and DE overall and across competition levels, and assessed the co-occurrence between the two risk classifications in female volleyball players in Türkiye, using the Low Energy Availability in Females Questionnaire (LEAF-Q) and Eating Attitudes Test-26 (EAT-26). It also examined correlations between EAT-26 total score and LEAF-Q total and domain scores. A total of 213 athletes, recruited via non-probability convenience sampling, completed the LEAF-Q and EAT-26 to assess LEA risk and DE risk, respectively. In this sample, 33.3% of athletes were classified as being at risk of LEA, with no difference across competition levels (p = 0.825). A total of 17.4% were classified as being at risk of DE, with variation across competition levels and the highest proportion among Turkish Women’s Volleyball Second League athletes (p = 0.034). LEA risk and DE risk co-occurred in 10.3% of the sample, and DE risk was associated with higher odds of LEA risk (unadjusted OR = 3.80, 95% CI: 1.82–7.92). EAT-26 total score was positively correlated with LEAF-Q total and gastrointestinal function scores (p < 0.001) and injury history score (p = 0.004), but not menstrual function score (p = 0.133). These results suggest that LEA risk was commonly identified in this sample, DE risk was comparatively less common, and their co-occurrence was only partial, highlighting the value of screening for both risks rather than assuming one from the other.
- MakaleAçık Erişim2026Scopus SJRQ3Low-Data Modeling of Shallow Foundations on Cohesive Slopes: A Comparison between Hybrid FEM–RSM and ML Models*
Kâmiloğlu, Hakan Alper; Gücüyener, Alper
In geotechnical engineering, accurately predicting the seismic bearing capacity of shallow foundations on cohesive slopes requires proper consideration of nonlinear effects and parameter interactions. However, most studies in the literature address these complex effects inadequately, either with numerical methods that demand a large number of analyses or with machine learning (ML) models that require large and heterogeneous data sets. In this study, it is aimed to propose an approach that allows for a robust analysis of the system and at the same time provides accurate forecasting for situations where working with small and homogeneous data sets is mandatory. Within the scope of the study, seismic bearing capacity analyses were performed using Plaxis 2D for 273 cases where eight independent variables took different values according to the Face Centered Composite Design (FCCD), and a database was created. Multiple Linear (MLR), Multiple Nonlinear (MNLR) Regression Models were established, and ML models, such as Support Vector Regression (SVR), Random Forest (RF), and Extreme Gradient Boosting (XGBoost), were trained. The models were compared with both in-sample and out-of-sample estimation performance, and parametric sensitivity analyses were evaluated by methods such as ANOVA and SHAP. The results show that the MNLR model with natural logarithmic transformation is the most successful method in terms of both accuracy (R² ≈ 0.98) and reflecting parameter interactions, while the SVR algorithm demonstrates the best generalization ability among ML models under low-data conditions. The results also confirm that the ML models effectively capture the parameter effects.
- MakaleAçık Erişim2026Scopus SJRQ1Shape-Directed Hydrothermal Design of Zinc Oxide Nanoparticles for Antimicrobial and Anticancer Applications
Özkan, Elvan Hasanoğlu; Yetim, Nurdan Kurnaz; Kızıl, Hamit E.; Öğütçü, Hatice
The emergence of antibiotic-resistant bacteria represents one of the most pressing challenges in global healthcare. In this study, metal oxide–based nanomaterials are gaining prominence due to their antimicrobial and anticancer potential. In the present study, six new zinc oxide nanoparticles (ZnO-NPs) synthesized via the hydrothermal method using different surfactants were characterized, and their biological activities were evaluated. ZnO-NPs, whose structural properties were determined by a range of analytical methods including BET, FT-IR, SEM-EDX, XRD, and XPS, exhibited significant antibacterial and antifungal effects on a range of bacterial and fungal strains. The study revealed that variations in the morphology and surface area had a direct impact on antimicrobial efficacy. In antimicrobial assays, the inhibition zones ranged from 10.5 mm to 25.5 mm, with ZnO-6 exhibiting the highest efficacy against S. epidermidis (25.5 mm). In cytotoxicity assays, ZnO-6 demonstrated the strongest anticancer potential against H460 cells with the lowest IC50 value of 31.9 µg/mL. Furthermore, a strong correlation was revealed between the physicochemical properties of ZnO-NPs and their anticancer activity, as evidenced by the results of tests conducted on H460 lung cancer cells. Specifically, ZnO-6, which possesses a flower-like morphology and the highest surface area, exhibited the strongest anticancer effect with an IC50 value of 31.9 µg/mL. The parallel enhancement in both antimicrobial and anticancer activities observed in ZnO-6 suggests a common underlying mechanism, likely driven by the high surface area and specific flower-like morphology that facilitates increased interaction with cell membranes and ROS generation. The findings demonstrate that the controlled design of ZnO-NPs in terms of morphology and surface area offers significant potential in both antimicrobial and anticancer applications.
AtıfScopus3WoS3OpenAlex2
İncele - MakaleYalnız künye2026Scopus SJRQ2Social support mediates relationship between death anxiety and stress in chronic illness
Akeren, Zahide; Kalyoncuo, Servet
Background: Fear of death may become salient among individuals with chronic illness. This study examined the mediating role of perceived social support in the relationship between death anxiety and perceived stress in individuals with chronic illness. Methods: The study was conducted with 265 individuals diagnosed with chronic illness. The sample included participants with hypertension (20.7%), diabetes (19.6%), and cardiovascular diseases (16.2%), among conditions. Data were collected using the Templer Death Anxiety Scale, the Perceived Stress Scale, and the Multidimensional Scale of Perceived Social Support. Results: A weak negative correlation was found between death anxiety and perceived social support (r = -0.156, p = 0.011), while a positive correlation was observed between death anxiety and perceived stress (r = 0.362, p < 0.001). The proportion of the total effect mediated by perceived social support was 32.7%. Death anxiety was associated with perceived stress (β = 0.347, p < 0.001). The of perceived social support as a mediator, the coefficient decreased (β = 0.234, p < 0.001), indicating partial mediation. Conclusion: Perceived social support partially mediated the relationship between death anxiety and perceived stress. Higher levels of death anxiety were associated with higher perceived stress, and this association was attenuated in the presence of perceived social support.
- MakaleYayıncıda açık erişim2026Scopus SJRQ3Effects of Artificial Weathering Resistance on the Hardness Value of Ash Wood Surfaces Coated with Polyurethane Modified Water-Based Varnish after Heat Treatment
Akter, Mete; Ulay, Göksel; Peker, Hüseyin; Çakıcıer, Nevzat; Atilgan, Abdi; Ayata, Ümit
Pendulum hardness test is important for determining the mechanical durability and long-term performance of the film layer formed on the surface of wood thermally treated at high temperatures and coated with water-based varnish (WBV). In this study, the effect of artificial weathering conditions on the pendulum hardness (König method) of ash (Fraxinus angustifolia Vahl.) wood samples varnished with polyurethane modified WBV was investigated. The samples were thermally treated under two conditions (190°C for 1.5 h and 212°C for 2 h) and compared with untreated control samples. The samples were exposed to artificial weathering conditions (for periods of 0, 168, 336 and 504 h). Pendulum hardness values were measured at the end of each weathering period. According to the results, increases in hardness values were observed in both heat-treated and untreated ash wood samples treated with varnish after weathering. In the varnished samples treated at 212°C for 2 h, the post-weathering hardness increases were lower compared to the samples treated at 190°C for 1.5 h and the control group. Additionally, analysis of variance for the pendulum hardness test, heat treatment, weathering time and their interaction were determined to be statistically significant. The significant increases in hardness values observed in the unweathered samples highlight the importance of the wood, varnish, and weathering process.
- MakaleAçık Erişim2026Scopus SJRQ2Diagnostic and Prognostic Significance of miR-155, miR-181, miR-221, miR-222, and miR-223 Expression in Myelodysplastic Syndromes and Acute Myeloid Leukemia
Ardıç, Cemile; Ay, Mustafa Ertan; Çevik, Kenan; Tombak, Anıl; İzci Ay, Özlem; Karakaş, Ümit; Doğru Özdemir, Gurbet; Bilgiç, Abdulkadir; Erdal, Mehmet Emin
Background: Myelodysplastic syndromes (MDSs) and acute myeloid leukemia (AML) are clonal hematological disorders that share molecular origins but present with distinct clinical features. MicroRNAs (miRNAs) are key post-transcriptional regulators, and their altered expression may reflect biological shifts contributing to disease progression. Methods: Expression levels of miR-155, miR-181, miR-221, miR-222, and miR-223 were analyzed by RT-qPCR in bone marrow samples from 37 MDS patients, 20 AML patients, and 7 controls. Group comparisons were performed using ANOVA (with Benjamini–Hochberg correction) and Tukey post hoc testing. Diagnostic performance and network behavior were evaluated using ROC analysis, Pearson correlation matrices, and principal component analysis (PCA). Results: miR-155, miR-181, and miR-223 were upregulated in AML, whereas miR-221 and miR-222 were downregulated. miR-222 showed the highest diagnostic accuracy (AUC ~0.87 for both AML vs. control and MDS vs. control). Its expression was significantly higher in high IPSS-R MDS cases (p = 0.046), with a similar upward tendency for miR-221 (p = 0.054). Progressive loss of coordinated miRNA expression was observed from controls to MDS and AML. PCA supported these findings by showing separation mainly driven by miR-222 and miR-155. Conclusions: Combined miRNA profiling highlights miR-222 and, to a lesser extent miR-155, as consistent indicators of myeloid disease transformation. While further validation in larger and genetically stratified cohorts is warranted, these findings support the potential contribution of miRNA signatures to diagnostic evaluation and risk stratification in MDS and AML, in line with precision hematology approaches.
AtıfScopus1WoS1OpenAlex1İncele - Derleme MakaleAçık Erişim2026Scopus SJRQ2SURVEILLANCE OR SUPPORT? A SYSTEMATIC LITERATURE REVIEW OF ARTIFICIAL INTELLIGENCE SUPPORTED PROCTORED ONLINE EXAMS
Ustun, Aysin Gaye; Kayali, Bunyami; Yavuz, Mehmet; Bozkurt, Aras
Proctored online exams have become widespread, especially after COVID-19, increasing exam security and efficiency. In recent years, artificial intelligence developments have increased these systems' importance by expanding their use. Accordingly, this study aims to provide an in-depth understanding of the conceptual structure of artificial intelligence-supported proctored online examination (AI-SPOE) research. Systematic literature review and text mining were used as methods. Thirty-two studies in Scopus and Web of Science databases were analyzed according to the PRISMA technique. While all the studies were examined in the context of content analysis, abstracts and keywords of the relevant studies were analyzed by text mining. The current study found it effective in increasing academic integrity and exam security, but problems such as privacy violations, exam anxiety, and algorithmic biases were encountered. Although methods such as biometric verification and behaviour analysis successfully detect cheating, technical difficulties, and false positives negatively affect the user experience. In the future, more inclusive designs, transparent algorithms, and alternative evaluation methods are suggested. In conclusion, the study emphasizes the potential of AI-SPOE systems and highlights the importance of ethical and technical improvements.
AtıfScopus1OpenAlex1İncele - MakaleYalnız künye2026Scopus SJRQ1Experimental investigation of magnetic forces in PMA and HTS configurations using a high-speed electrodynamic levitation test system
Mollahasanoglu, Hakkı; Abdioglu, Murat; Ozturk, Ufuk Kemal; Okumus, Halil Ibrahim
This study presents a comparative experimental investigation of magnetic force parameters in high-speed electrodynamic levitation systems using permanent magnet arrays and high-temperature superconductors. A novel modular test platform with a rotating aluminium rail, cryostat, and integrated three-axis force measurement unit was employed to evaluate levitation and drag forces under controlled conditions at linear velocities up to 280 km/h. Three different permanent magnet arrays configurations were designed and tested at working gaps of 10, 12, and 15 mm, while high-temperature superconductors bulks fabricated from YBCO by the top-seed-melt-growth method were tested at 10 and 12 mm gaps. The experimental results demonstrated that permanent magnet arrays configurations produced higher levitation forces, with a maximum of 100 N at working gap of 10 mm. High-temperature superconductors bulks, in contrast, generated lower levitation forces (maximum 17 N at 10 mm) due to limited trapped flux (∼0.25 T) but showed the advantage of substantially reduced drag forces (3.5 N at 10 mm). A lift-to-drag ratio analysis confirmed the trade-off between force generation and energy losses in permanent magnet arrays systems, while highlighting the efficiency potential of high-temperature superconductors-based levitation. The findings of this study provide valuable insights for the engineering development of high-temperature superconductors-based Maglev technologies, emphasizing their potential importance in future transportation systems.
AtıfScopus5WoS4OpenAlex2İncele
