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- Derleme MakaleAçık Erişim2025Scopus SJRQ1Evaluation of the Effect of Sustainable Drying Techniques and Intensification Technologies on Color Profile of Dehydrated Fruits and Vegetables
Süfer, Ozge; Koç, Gulsah Caliskan; Öztekin, Sebahat; Karabacak, Azime Ozkan; Su, Dianbin; Wang, Deqing; Eroglu, Salih; Malçok, Senanur Durgut; Uslu, Ulku Hilal; Adal, Samiye
This research investigates the effects of various drying procedures and intensification technologies on the color profile of dried fruits and vegetables. The primary goal is to identify the most effective techniques for minimizing degradation, which is frequently caused by exposure to heat, oxygen, and longer drying durations, while retaining the original color of these products. Although conventional techniques like sun and hot air drying are often employed, enzymatic and non-enzymatic brownings usually cause a considerable loss of color. New technologies aim to better preserve the original color by cutting down on processing temperature and drying time. The paper also looks at the possibilities of hybrid drying approaches, which combine techniques such as infrared hot air drying and microwave hot air drying. These methods have been demonstrated to be especially successful in preserving color integrity and enhancing drying process effectiveness. The results highlight the vital significance that parameter optimization and drying technique selection play in maintaining the nutritional value and aesthetic appeal of dehydrated fruits and vegetables. This study emphasizes the significance of developing drying technologies to satisfy consumer desires for premium, aesthetically pleasing food goods, because color is a major factor in determining consumer acceptance and perceived product quality. With wider implications for food preservation and the food industry overall, this work helps to develop more effective and efficient drying processes by shedding light on how various drying techniques affect color retention.
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İncele - MakaleAçık Erişim2026Scopus SJRQ1Measuring Sustainability Under Uncertainty: Introducing Net ESG (N-ESG) Performance
Ongan, Serdar; Isik, Cem; Aydin, Rahman; Imamoglu, Ilyas Kays; Alvarado, Rafael; Ahmad, Munir
This study examines the reliability of environmental, social, and governance (ESG) scores in uncertain environments by introducing a new indicator, Net ESG (N-ESG), for the first time. This new index was calculated by subtracting a new ESG-based sustainability uncertainty index (ESGUI) from ESG scores. This study employed Pedroni (2004) and Westerlund (2007) tests, as well as the DOLS method, for 12 developed countries from 2002 to 2020. It analyzed the impact of economic, geopolitical, climate, and energy price-related uncertainties on both ESG and N-ESG through eight different models. Empirical findings indicate that a 1% change in CPU, GPR, EPU, and OPU indices increases ESG by 0.048, 0.355, 0.111, and 0.044 units, respectively, while the same rate of change decreases N-ESG by -6.501, -18.756, -8.972, and -8.193 units, respectively. These results can be interpreted as ESG scores may not fully reflect the true performance of companies in times of uncertainty, while N-ESG provides a more accurate representation of sustainability practices. These results suggest that policymakers should focus their sustainability policies not only on increasing ESG scores but also on preserving the true value of ESG by reducing uncertainty effects.
AtıfScopus36WoS36OpenAlex38İncele - MakaleAçık Erişim2026Scopus SJRQ1Upper extremity muscle thickness and grip strength following a boccia-based intervention in hemiparetic individuals
Hazar, Emre Berk; Güder, Betul Canbolat; Hazar, Kursat; Gök, Umut Diyar; Alkhamees, Nouf H.; Ibrahim, Zizi M.; Al-Mhanna, Sameer Badri; Batrakoulis, Alexios
Introduction The global prevalence of stroke is increasing, highlighting the critical importance of effective post-stroke rehabilitation. Although boccia was originally designed for individuals with special needs, its potential benefits for stroke rehabilitation, particularly regarding task-related changes in ultrasound-observed muscle characteristics, have not been thoroughly investigated. Purpose This study aimed to examine the association of an 8-week boccia-based intervention with changes in upper extremity muscle thickness and grip strength in individuals with hemiparesis following stroke. Methods A total of 22 stroke survivors were randomly allocated to a boccia group (Boc, n = 12) or a control group (Ctrl, n = 10). While the control group received conventional physical therapy for eight weeks, the boccia group participated in both physical therapy and boccia-based intervention three times per week. Upper extremity muscle thickness and grip strength were assessed before and after the intervention. Results In the control group, a significant increase was observed only in the triceps brachii muscle thickness. In contrast, the boccia group demonstrated statistically detectable increases in forearm muscles (flexor digitorum profundus, flexor digitorum superficialis, pronator teres, and brachioradialis), triceps brachii muscle thickness, and grip strength. Conclusion Incorporating boccia-based intervention into the rehabilitation programs of individuals with hemiparesis after stroke may be associated with broader upper extremity muscle involvement and concurrent improvements in grip strength. These findings should be interpreted as exploratory and hypothesis-generating.
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İncele - MakaleAçık Erişim2023Scopus SJRQ2Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes' Competitive Performance
Bulgay, Celal; Bayraktar, Isik; Kazan, Hasan Huseyin; Yildirim, Damla Selin; Zorba, Erdal; Akman, Onur; Ergun, Mehmet Ali; Cerit, Mesut; Ulucan, Korkut; Eken, Ozgur
The present study aimed to examine the vitamin D receptor (VDR), rs2228570 polymorphism, and its effect on elite athletes' performance. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/ physically inactive, aged 18-35, voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the athletes' personal best (PB). Whole exome sequencing (WES) was performed by the genomic DNA isolated from the peripheral blood of the participants. Sports type, sex, and competitive performance were chosen as the parameters to compare within and between the groups by linear regression models. The results showed no statistically significant difference between the CC, TC, and TT genotypes within and between the groups (p > 0.05). Additionally, our results underlined that there were no statistically significant differences for the association of rs2228570 polymorphism with PBs within the groups of the (p > 0.05) athletes. The genetic profile in the selected gene was similar in elite endurance, sprint athletes, and in controls, suggesting that rs2228570 polymorphism does not determine competitive performance in the analyzed athlete cohort.
AtıfScopus11WoS10OpenAlex15İncele - MakaleAçık Erişim2025Scopus SJRQ2A comparative analysis of teachers' attitudes towards including all students in six countries
Charitaki, Garyfalia; Kourti, Isidora; Gregory, Jess L.; Ozturk, Mesut; Ismail, Zaleha; Alevriadou, Anastasia; Soulis, Spyridon-Georgios; Kypriotaki, Maria; Sakici, Sehnaz; Demirel, Can
This study aims to explore differences across Greece, the UK, the USA, Malaysia, Romania, and Turkey in terms of their attitudes towards inclusive education and validate the three-model structure for attitudes towards inclusion across the above six countries. All special education teachers were administered the ATTAS-mm scale. They were employed in mainstream schools or parallel support and/or resource classes in six countries. The identified differences were interpreted regarding the effect of years of teaching experience, educational work level of teachers, and the highest degree completed across the different participating countries. Two-step cluster analysis suggested a two-cluster solution for Greece, the USA and the UK, and a three-cluster solution for Malaysia and Turkey. Finally, years of teaching experience, educational work level, and the highest degree completed had a significant effect on teachers' attitudes towards inclusion in all countries. Results are discussed for their implications in teachers training.
AtıfScopus7WoS6OpenAlex10İncele - MakaleAçık Erişim2020Scopus SJRQ2Investigation of neutron and gamma radiation protective characteristics of synthesized quinoline derivatives
Aygün, Bunyamin; Alaylar, Burak; Turhan, Kadir; Sakar, Erdem; Karadayi, Mehmet; Abu Al-Sayyed, Ibrahim; Pelit, Emel; Güllüce, Medine; Karabulut, Abdulhalik; Turgut, Zuhal
Purpose: Quinoline is formed by various natural compounds, such as alkaloids from the cinchona plant, which exhibit various biological activities, and is an important building material for the development of new drugs. Quinoline can be used in anti-radiation drug development but radiation interaction properties must be determined. Material and methods: In this study, six types of synthesized quinoline derivatives were used. Fast neutron removal cross-section, mean free path, half value layer and transmission number were theoretically determined by using GEometry ANd Tracking 4 and FLUktuierende KAskade simulation codes for neutron shielding. Neutron dose absorption rates were determined using the(241)Am-Be fast neutron source and the Canberra NP series portable BF(3)gas proportional neutron detector. Gamma radiation shielding parameters were determined by using WinXCom and PSY-X/PSD software. Additionally, the genotoxic potentials of the derivatives were assessed by using the Ames/Salmonellabacterial reversion assay. Results and conclusions: Neutron shielding parameters such as removal cross-section, mean free path, half value layer and transmission number were theoretically determined for fast neutrons. To determine neutron absorption capacity of quinoline derivatives, neutron absorption, experiments were conducted. In addition, gamma radiation shielding parameters were calculated such as the mean free path (MFP), mass attenuation coefficient (mu t), half value thickness layer (HVL) and effective atomic number (Zeff) in the energy range of 0.015-15 MeV. The results of the all quinoline derivatives have excellent fast neutron shielding power compared to ordinary concrete. In addition, all quinoline derivatives have been found to have the capacity to attenuate gamma radiation. Moreover, they absorb well in both types of radiation, do not cause secondary radiation, and they are genotoxically safe at the tested concentrations. This study has demonstrated that these products can be used as active ingredients for a drug to be developed against radiation.
AtıfScopus47WoS47OpenAlex52İncele - MakaleYayıncıda açık erişim2024Scopus SJRQ2The ARK2N (C18ORF25) Genetic Variant Is Associated with Muscle Fiber Size and Strength Athlete Status
Çigirtas, Rukiye; Bulgay, Celal; Kazan, Hasan Hueseyin; Akman, Onur; Sporis, Goran; John, George; Yusupov, Rinat A.; Sultanov, Rinat I.; Zhelankin, Andrey V.; Semenova, Ekaterina A.
Background: Data on the genetic factors contributing to inter-individual variability in muscle fiber size are limited. Recent research has demonstrated that mice lacking the Arkadia (RNF111) N-terminal-like PKA signaling regulator 2N (Ark2n; also known as C18orf25) gene exhibit reduced muscle fiber size, contraction force, and exercise capacity, along with defects in calcium handling within fast-twitch muscle fibers. However, the role of the ARK2N gene in human muscle physiology, and particularly in athletic populations, remains poorly understood. The aim of this study was threefold: (a) to compare ARK2N gene expression between power and endurance athletes; (b) to analyze the relationship between ARK2N gene expression and muscle fiber composition; and (c) to investigate the association between the functional variant of the ARK2N gene, muscle fiber size, and sport-related phenotypes. Results: We found that ARK2N gene expression was significantly higher in power athletes compared to endurance athletes (p = 0.042) and was positively associated with the proportion of oxidative fast-twitch (type IIA) muscle fibers in untrained subjects (p = 0.017, adjusted for age and sex). Additionally, we observed that the ARK2N rs6507691 T allele, which predicts high ARK2N gene expression (p = 3.8 x 10-12), was associated with a greater cross-sectional area of fast-twitch muscle fibers in strength athletes (p = 0.015) and was over-represented in world-class strength athletes (38.6%; OR = 2.2, p = 0.023) and wrestlers (33.8%; OR = 1.8, p = 0.044) compared to controls (22.0%). Conclusions: In conclusion, ARK2N appears to be a gene specific to oxidative fast-twitch myofibers, with its functional variant being associated with muscle fiber size and strength-athlete status.
AtıfScopus8WoS7OpenAlex8İncele - MakaleAçık Erişim2025Scopus SJRQ1The Role of Women's Entrepreneurship, Unemployment, Global Warming, and Technology in Sustainable Development: Evidence From OECD Countries
Isik, Cem; Ongan, Serdar; Günlü, Ebru; Aydin, Rahman; Imamoglu, Ilyas Kays
This study examines the effects of women's entrepreneurship, global warming, technological advancements, and unemployment on the achievement of the sustainable development goals (SDGs) across 38 OECD countries. Using country-specific panel causality methods, the analysis reveals significant asymmetries between developed and developing economies. Women's entrepreneurship (FEM) and technology (TEC) demonstrate stronger positive effects in developing countries such as Mexico, Slovakia, and Costa Rica, supporting SDGs 5 and 9. Global warming (SUR) negatively affects both groups, with notable impacts in Belgium, Mexico, and the UK, emphasizing the urgency of SDG 13. Unemployment (UNM) poses greater threats to sustainable development in emerging economies-particularly in Turkey and Latin American nations-while its influence remains limited in advanced countries. These results underscore the heterogeneous nature of SDG progress and suggest that universal, one-size-fits-all policies may fall short. Instead, national strategies should strengthen gender-inclusive entrepreneurship and innovation, while mitigating climate risks and labor market vulnerabilities. This paper presents a novel, multidimensional econometric framework and offers original insights into how interlinked economic, social, and environmental factors influence sustainability outcomes across diverse national contexts.
AtıfScopus23WoS18OpenAlex21İncele - MakaleYalnız künye2021Scopus SJRQ2Differential effects of inhibitors of PTZ-induced kindling on glutamate transporters and enzyme expression
Taspinar, Numan; Hacimuftuoglu, Ahmet; Butuner, Selcuk; Togar, Basak; Arslan, Gokhan; Taghizadehghalehjoughi, Ali; Okkay, Ufuk; Agar, Erdal; Stephens, Robert, Jr.; Turkez, Hasan
Epilepsy is a neurological disorder resulting from abnormal neuronal firing in the brain. Glutamate transporters and the glutamate-glutamine cycle play crucial roles in the development of seizures. In the present study, the correlation of epilepsy with glutamate transporters and enzymes was investigated. Herein, male Wistar rats were randomly allocated into four groups (six animals/group); 35 mg/kg pentylenetetrazole (PTZ) was used to induce a kindling model of epilepsy. Once the kindling model was established, animals were treated for 15 days with either valproic acid (VPA, 350 mg/kg) or ceftriaxone (CEF, 200 mg/kg) in addition to the control group receiving saline. After treatment, electrocorticography (ECoG) was performed to record the electrical activity of the cerebral cortex. The glutamate reuptake time (T-80) was also determined in situ using an in vivo voltammetry. The expression levels of glutamate transporters and enzymes in the M1 and CA3 areas of the brain were determined using a real-time polymerase chain reaction (RT-PCR). ECoG measurements showed that the mean spike number of the PTZ + VPA and PTZ + CEF groups was significantly lower (p < 0.05) than that of the PTZ group. Compared with the PTZ group, VPA or CEF treatment decreased the glutamate reuptake time (T-80). The expression levels of EAAC1, GLT-1, GLAST, glutamine synthetase (GS), and glutaminase were increased in the PTZ group. Treatment with VPA or CEF enhanced the expression levels of GLT-1, GLAST, EAAC1, and GS, whereas the glutaminase expression level was reduced. The current results suggest that VPA or CEF decreases seizure activity by increasing glutamate reuptake by upregulating GLT-1 and GLAST expression, implying a possible mechanism for treating epilepsy. Also, we have suggested a novel mechanism for the antiepileptic activity of VPA via decreasing glutaminase expression levels. To our knowledge, this is the first study to measure the glutamate reuptake time in situ during the seizure (i.e., real-time measurement).
AtıfScopus14WoS15OpenAlex16İncele - MakaleYalnız künye2018Scopus SJRQ3DIFFERENT LAND USE INFLUENCES ON AMINO ACID, ORGANIC ACID, HORMONE AND MINERAL NUTRIENT CONTENTS OF DRY BEANS
Erdogan, Ummugulsum; Kitir, Nurgul; Günes, Adem; Tuan, Metin; Tasci, Sinem; Yildirim, Ertan; Karaman, Mehmet Rustu; Mokhtari, Negar Ebrahim Pour; Ozlu, Ekrem; Firildak, Gulay
Dry bean (Phaseolus vulgaris L.) is a widely grown and important food legume which is a major source of mineral nutrition. The present study digs in determining differences in nutrients, organic-amino acid and hormone concentrations of Ispir bean genotypes under different land use conditions. The study sites (32 locations) were identified according to the stratified sampling method in the Ispir district, Erzurum, Turkey, under consideration of bean-cultivated lands and the number of villages. The seed weights were higher for genotype no. 4 (137.5 g) than for genotype no. 14 (131.5 g) and following by all other genotypes. Moreover, values for crude protein content were significantly higher for genotype no. 14 (263.1 g/kg) in comparison to genotype no. 4 (256.9 g/kg) and other genotypes. Therefore, it is concluded that land use impacts seed weight, nutrient, crude protein, amino acid, organic acid and hormone contents of Ispir dry bean. Land use can result economic improvements in crop yields and yield components. Dry bean seed weights were impacted by other crop yield components such as amino acid, organic acid and hormone contents of dry bean.
- MakaleAçık Erişim2023Scopus SJRQ1Reproductive Effects of S. boulardii on Sub-Chronic Acetamiprid and Imidacloprid Toxicity in Male Rats
Sevim, Cigdem; Akpinar, Erol; Aksu, Emrah Hicazi; Ömür, Ali Dogan; Yildirim, Serkan; Kara, Mehtap; Bolat, Ismail; Tsatsakis, Aristides; Mesnage, Robin; Golokhvast, Kirill S. S.
The potential health-promoting effects of probiotics against intoxication by pesticides is a topic of increasing commercial interest with limited scientific evidence. In this study, we aimed to investigate the positive effects of probiotic Saccharomyces boulardii on the male reproductive system under low dose neonicotinoid pesticide exposure conditions. We observed that acetamiprid and imidacloprid caused a degeneration and necrosis of the spermatocytes in the tubular wall, a severe edema of the intertubular region and a hyperemia. This was concomittant to increased levels of 8-hydroxy-2 '-deoxyguanosine reflecting oxidative stress, and an increase in caspase 3 expression, reflecting apoptosis. According to our results, Saccharomyces boulardii supplementation mitigates these toxic effects. Further in vivo and clinical studies are needed to clarify the molecular mechanisms of protection. Altogether, our study reinforces the burden of evidence from emerging studies linking the composition of the gut microbiome to the function of the reproductive system.
AtıfScopus20WoS19OpenAlex24İncele - MakaleAçık Erişim2025Scopus SJRQ1Quantification of Honey Adulteration Using a Planar Microstrip Metamaterial-Motivated Sensor and Software-Defined Radio
Cem Hasar, Ugur; Hasar, Hafize; Kaya, Yunus; Ozturk, Hamdullah; Korkmaz, Huseyin; Kosunalp, Selahattin; Iliev, Teodor; Tariqul Islam, Mohammad; Nayyeri, Vahid; Mustafa Ramahi, Omar
This work presents the application of a planar microstrip metamaterial (MM)-motivated sensor in the form of a split-ring resonator (SRR) for the detection and quantification of water adulteration in honey samples. The proposed sensor utilizes inexpensive software-defined radio (SDR) measurements, offering a cost-effective solution. Unlike previous MM sensors employing SRR configuration, our proposed MM-motivated sensor is integrated with a microstrip feedline and an additional vertical bar, enhancing its sensing capability. To enable accurate measurements, a simple calibration procedure based on baseline normalization is implemented, allowing for amplitude-only transmission measurements (|S-21|) using the SDR. A special sample holder was designed to increase the repeatability of measurements. We separately employ two postprocessing techniques, namely, the rolling average (RA) approach and the Savitzky-Golay (SG) filter, to effectively eliminate ripples in the measured |S-21| data obtained from the SDR. For validation and evaluation of the proposed sensor and postprocessing techniques, measurements of flower honey samples with water adulteration levels (delta ) up to 10% (mass-to-mass basis) were also performed using a vector network analyzer (VNA). The resonance frequency of |S21| is utilized as the basis for analysis. We establish a metric function (linear function) that correlates the shift in resonance frequency with delta. It is observed that this function fits to measured resonance frequency values with an R(2 )value greater than 0.96 for both postprocessing techniques with or without the sample holder. By inverting this function, we can predict delta with considerable accuracy for a given resonance frequency by using another linear function. It is observed that percentage variations between predicted and measured delta values are between 1.54% and 6.46% for testing samples with delta = 5% and delta = 7%.
AtıfScopus5WoS2OpenAlex5İncele - MakaleAçık Erişim2026Scopus SJRQ1Does Climate Change Vulnerability Cause Energy Vulnerability in Sustainable Development?
Isik, Cem; Ongan, Serdar; Kuziboev, Bekhzod; Imamoglu, Ilyas Kays
Climate change and energy security are two fundamental vulnerability areas that interact with each other and hold critical importance for sustainable development goals. This research aims to fill the research gap by investigating the effects of climate change vulnerability (CCV) on the energy vulnerability (EV) relationship, which has not been adequately addressed in the literature, using a large panel dataset covering 74 countries and employing various methodological approaches (MMQR, PLFC, DID). The results of the MMQR model indicate that CCV increases EV across all quantiles. According to the results of the PLFC model, it is revealed that CCV on EV varies depending on the economic development level of countries. This effect is higher in low-income countries. The study also employs the DID model to examine the impact of China's foreign energy investments on countries' EV. According to this model, China's fossil-based energy investments, particularly those in the energy sector, increase the EV of countries. While economic development reduces EV across all quantiles, financial development reduces it in the lower and medium quantiles (25% and 50%); urbanization reduces it in the medium and higher quantiles (50% and 75%). All results show that the interaction between EV and CCV is a multidimensional and dynamic process. Accordingly, policymakers should develop integrated strategies that consider environment and energy policies, economic development, investment type, and environmental risks. Lastly, policymakers should consider energy investments from China not only as a tool for their country's economic growth, but also in terms of energy security and sustainability.
AtıfScopus22WoS22OpenAlex23İncele - MakaleYalnız künye2026Scopus SJRQ1Economic, Environmental, Social, and Governance (ECON - ESG) Strategies For Sustainable Development: Theory and a Holistic Evidence From Germany
Isik, Cem; Ongan, Serdar; Aydin, Rahman; Imamoglu, Ilyas kays
To achieve the SDGs, in addition to environmental (E), social (S), and governance (G) indicators, economic components should also be evaluated holistically. In this context, this research aims to test the time series characteristics of the indicators in the ECON-ESG structure, which is created by integrating the economic dimension into the ESG framework for Germany. For this purpose, linear and nonlinear structures, Fourier-based stationarity tests, and Bai-Perron multiple structural break tests were employed to examine the linear and nonlinear structures, stationarity cases, and structural breaks of various ESG and economic indicators (ECON). Findings show that many indicators are nonstationary, undergo structural changes over time, and exhibit nonlinear dynamics. The results indicate that sustainability policies should focus not only on indicator levels but also on the behavioral patterns and vulnerabilities of these indicators over time. In this regard, policymakers need to develop a holistic perspective on the economy and ESG, focusing on long-term and flexible policy designs. The study also offers important implications for how the ECON-ESG framework can serve as a model for both national and international markets, particularly in Germany, a developed and leading country in terms of sustainability. Therefore, the proposed ECON-ESG framework offers both theoretical and practical roadmaps for policymakers, firms, and investors to create long-term ESG strategies in support of the SDGs.
AtıfScopus74WoS75İncele - MakaleAçık Erişim2023Scopus SJRQ3Relationship of progranulin response with some physio-biochemical parameters in Akkaraman sheep
Bayraktar, Buelent; Tekce, Emre; Genç, Murat; Kaya, Hacer; Özcan, Gulbahar Boyuk; Aydemir, Seyma; Kotan, Goksad Cemil; Takma, Cigdem; Ürüsan, Hilal; Aksakal, Vecihi
Progranulin (PGRN) is a multifunctional protein that is critical in the retention of embryos in the endometrium of the uterus and the protection of cervical tissue during fetal growth. In case of PGRN release and dysfunction, cervical tissue may remodel (regeneration) and lead to the risk of abortion. Serum PGRN level in sheep and its variation according to different physiological periods and its relationship with some biochemical parameters are unknown. In this study, the relationship between early lactation, early and late pregnancy serum PGRN levels and some biochemical parameters in Akkaraman sheep was investigated for the first time. In the literature search, no similar studies were found on the relationship between early lactation, early and late pregnancy serum PGRN levels and some biochemical parameters in Akkaraman sheep. The research was carried out on 90 Akkaraman sheep reared in the same herd under the same care and feeding conditions. In the study, Akkaraman ewe were divided into 3 groups as early lactation, early pregnancy and late pregnancy. 1st group is early lactation period ewe (first 60 days of lactation), (n = 30), 2nd group is in the first period of pregnancy (on the 0-90th day of the first pregnancy (n = 30)), 3rd group is in the late pregnancy of pregnancy (100-150 days of pregnancy (n = 30)) was created. Blood samples from vena jugularis were taken before morning feeding from the animals that formed the study groups. PGRN levels in serum were determined by ELISA method. In addition, glucose, calcium (Ca), magnesium (Mg), phosphorus (P), total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL) levels were analyzed in biochemistry autoanalyzer. As a result of the study, lactation and early pregnancy and late pregnancy mean serum PGRN levels were determined as 1.93, 1.78, 1.33 ng mL-1, respectively. The serum PGRN, glucose, Ca, Mg, P, TC, TG, LDL, HDL and VLDL levels of sheep with late pregnancy, early lactation and early pregnancy periods, which constitute the study groups, were found to be statistically significant (P<0.05). Our results have shown that due to the physiological role of PRGN in keeping the embryo in the endometrium of the uterine and in preserving the cervical tissue during fetal growth, there may be a useful parameter in the pursuit of the pregnancy process.
AtıfScopus4WoS4OpenAlex3İncele - MakaleAçık Erişim2026Scopus SJRQ1Effect of Perioperative Supplementation with Arginine and Omega-3 on Postoperative Complications in Patients Undergoing Gastrointestinal Cancer Surgery: A Pilot Open-Label Randomized Controlled Trial
Sakhri, Saida; Othman, Rym Ben; Jerbi, Chaima; Ceylan, Halil Ibrahim; Naija, Lamia; Zemni, Ines; Jamoussi, Henda; Dhiab, Tarek Ben; Ceylan, Nagihan Burcak; Stefanica, Valentina
Background: Perioperative immunonutrition, including arginine and omega-3 fatty acids, has been proposed to support postoperative recovery by modulating immune function. Aim: To evaluate the effects of perioperative arginine and omega-3 supplementation on postoperative infectious complications, mortality, hospital length of stay, intensive care unit duration, and inflammatory markers in patients undergoing gastrointestinal cancer surgery. Methods: In this Pilot Open-Label randomized trial, 35 adult patients scheduled for elective gastrointestinal cancer surgery at Salah Azaiez Institute were randomly assigned to receive either perioperative immunonutrition (n = 18; three daily capsules of omega-3 and one sachet of Arginine+ for 7 days preoperatively and 7 days postoperatively) or standard care (n = 17). Primary endpoints were postoperative infectious complications and 1-month mortality. Secondary endpoints included hospital length of stay, ICU duration, and postoperative biochemical markers. Results: No statistically significant differences were observed between groups in 1-month mortality (p = 0.324), hospital length of stay (median 7 vs. 7 days, p = 0.392), or ICU duration (median 5 vs. 6 days, p = 0.601). Urinary tract infection (5.9% vs. 11.1%, p = 0.939) and wound infection rates (5.9% vs. 11.1%, p = 0.581) were comparable. Importantly, postoperative C-reactive protein and other inflammatory markers did not differ significantly between groups (CRP: 165 vs. 175 mg/L; intergroup p = 0.798). Conclusions: In this trial, perioperative immunonutrition with arginine and omega-3 fatty acids did not improve postoperative clinical outcomes or inflammatory markers in patients undergoing gastrointestinal cancer surgery. At the administered dose and within a small, heterogeneous cohort, immunonutrition did not provide additional benefit beyond standard care. Larger, adequately powered multicenter trials with optimized dosing are required to clarify its role in gastrointestinal oncology.
AtıfScopus3WoS2OpenAlex2İncele - MakaleAçık Erişim2024Scopus SJRQ1Simple and inexpensive microwave setup for industrial based applications: Quantification of flower honey adulteration as a case study
Hasar, Ugur C.; Hasar, Hafize; Ozturk, Hamdullah; Korkmaz, Huseyin; Kaya, Yunus; Ozkaya, Mehmet Akif; Ebrahimi, Amir; Barroso, Joaquim J.; Nayyeri, Vahid; Ramahi, Omar M.
A simple and inexpensive microwave measurement setup based on measurements of magnitudes of transmission properties ( | S 21 | dB \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}|S₂₁|_dB\end{document} ) is proposed for industrial-based microwave aquametry (moisture or water content) applications. An easy-to-apply calibration procedure based on normalization is implemented to eliminate systematic errors in the measurement system. As a case study, we applied this setup for the quantification of water-adulteration in flower honey. After validating this system by distilled water and pure flower honey measurements, | S 21 | dB \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}|S₂₁|_dB\end{document} measurements of the pure flower honey with various adulteration percentages ( delta \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}δ\end{document} ) up to 9% are conducted to examine the performance of the measurement setup for quantification of water adulteration. A multi-dimensional fitting procedure is implemented to predict delta \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}δ\end{document} using the proposed inexpensive microwave measurement setup. It is shown that it is possible to quantify an adulteration level with an accuracy better than -/+ 1 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}∓ 1\end{document} % by the proposed measurement setup and the applied multi-dimensional fitting procedure.
AtıfScopus12WoS10OpenAlex15İncele - MakaleAçık Erişim2025Scopus SJRQ3A Social Approach to Environmental Sustainability: The Nexus Well-Being, Tourism, Digitalization and Renewable Energy in Scandinavian Countries
Isik, Cem; Ongan, Serdar; Aydin, Buket; Aydin, Rahman; Imamoglu, Ilyas Kays
This research explores the impact of subjective well-being (SWB) on CO2 emissions in Scandinavian countries based on the need to analyze the effects of social indicators shaping environmental sustainability. The study aims to introduce the Welfare-Based SWB approach to the literature by expanding the classical Environmental Kuznets Curve (EKC) hypothesis with the social welfare dimension. SWB is considered in this study to be a social reflection and indirect measure of economic growth, which is the core determinant in the classical EKC hypothesis. The second-generation cointegration test, the Durbin-Hausman, and AMG long-term forecasting methods were used in this context. According to the empirical findings, SWB and digitalization increase carbon emissions, while tourism revenues and renewable energy consumption reduce emissions. The findings indicate that the classical EKC hypothesis is not confirmed and, similarly, an increase in social welfare (SWB) does not automatically lead to environmental improvement. Therefore, policymakers should develop social policies that will increase environmental sensitivity along with an increase in welfare.
AtıfScopus16WoS13OpenAlex16İncele - MakaleAçık Erişim2025Scopus SJRQ1Characterizations and In Vitro Gut Microbiome Modulatory Effects of Gluco-Oligosaccharides Synthesized by the Acceptor Reactions of Glucansucrase 53
Bayaman, Rabia Yusra; Alkay, Zuhal; Ispirli, Humeyra; Arioglu-Tuncil, Seda; Dere, Sevda; Can, Hasan; Gonzales, Miguel Angel Alvarez; Sagdic, Osman; Lindemann, Stephen R.; Tuncil, Yunus Emre
The production of novel oligosaccharides with potential prebiotic effects is of interest to expand the current market and explore the effectiveness of new functional carbohydrate forms. The utilization of glucansucrases is a cost-effective and environmentally friendly biotechnological strategy for producing novel gluco-oligosaccharides through acceptor reactions. In this study, an active glucansucrase (GS53) was used to produce gluco-oligosaccharides via its acceptor reactions with glucose, maltose, and maltotriose, and these oligosaccharides were tested in terms of structure and their gut microbiome modulatory effects. The formations of oligosaccharides were monitored by TLC analysis, and GS53 was active for the three acceptors but not for the other sugars tested. The structural characterization of the gluco-oligosaccharides by 1H NMR analysis revealed the glycosylation of each acceptor with alpha-(1 -> 3) and alpha-(1 -> 6) linkages, whereas LC-MS analysis demonstrated the formations of DP 8, DP 7, and DP 6 oligosaccharides with acceptors maltose, maltotriose, and glucose, respectively. In vitro fecal fermentation analysis, in which microbial short-chain fatty acids (SCFAs) and microbial compositional changes were assessed using gas chromatography and 16S rRNA sequencing, respectively, demonstrated that the gluco-oligosaccharides formed SCFAs-particularly propionate and butyrate-at levels comparable to those observed with inulin, a well-established prebiotic. Additionally, the gluco-oligosaccharides were found to promote the growth of Bifidobacterium adolescentis and Blautia OTUs, which are known to have important physiological functions beneficial to human health. Overall, these results demonstrate that gluco-oligosaccharides synthesized using GS53 through acceptor reactions exhibit prebiotic potentials and could be utilized in the future as dietary supplements as well as in the development of functional foods targeting colonic health.
AtıfScopus3WoS3OpenAlex3İncele - MakaleYalnız künye2023Scopus SJRQ1Bulk MgB2 superconductor for levitation applications fabricated with boron processed by different routes
Savaskan, B.; Ozturk, U. K.; Guner, S. B.; Abdioglu, M.; Bahadir, M. V.; Acar, S.; Somer, M.; Ionescu, A. M.; Locovei, C.; Enculescu, M.
Bulk MgB2 discs were prepared by an in situ route from mixtures of magnesium and boron powders. The boron powders were produced by two methods. The first one consisted of a self-propagating high tem-perature magnesiothermic synthesis (SHS) process followed by acid and fluorine cleaning and a heat treatment in inert atmosphere. This approach produced boron with purities between 86 % and 97 %, where the main impurity was Mg. Depending on the final heat treatment, these boron powders were amorphous or crystalline. In the second route, high purity nano powders (99 %) of boron were obtained by a diborane pyrolysis process. Bulks of MgB2 were characterized by structural, microstructural, and magnetic mea-surements. Critical current density, pinning force aspects and levitation force (including guiding force) details were assessed. Amorphous lower purity boron (86-97 %) obtained by the first processing route was found to promote the largest levitation forces of the MgB2 bulks and, among these samples, the best le-vitation results were recorded when using boron with a purity of 95-97 %. Use of a lower purity boron that decreases the cost of MgB2 promotes large scale production at industrial level of bulk MgB2 super-conducting magnets for levitation applications and enhances the applicability potential of MgB2 super-conductor. The relationship between levitation force and specific features of the samples such as pinning force details are discussed.& COPY; 2023 Elsevier B.V. All rights reserved.
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