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Koleksiyondaki öğeler
- Kitap BölümüYalnız künye2020Diaspora tourism
Aykaç, Emre; Apak, Ömer Ceyhun
A compilation of current academic studies on the tourism sector of Turkey, the 23 chapters of this book have been written by tourism academicians who are experts in their respective fields. The chapters contain qualitative or quantitative research data and current statistical data, making this book useful for academic research. I thank all the contributors and dedicate this book to my family.
- MakaleAçık Erişim2022Scopus SJRQ1Assessment of technological attributes of autochthonous starter cultures in Turkish dry fermented sausage (sucuk)
Kaban, Güzin; Sallan, Selen; Çinar Topçu, Kübra; Sayın Börekçi, Bilge; Kaya, Mükerrem
The study aims to evaluate the technological properties of autochthonous strains (Lactobacillus sakei S15, Lactobacillus plantarum S24, L. plantarum S91, Pediococcus pentosaceus S128b and Staphylococcus carnosus G109) in Turkish dry fermented sausage (sucuk). After 24 h of fermentaPtion, all lactic acid bacteria strains reduced the pH to below 5.0, while the pH in the control group was above 5.3. The number of lactic acid bacteria strains reached 108–109 cfu g−1 during fermentation. Staphylococcus carnosus G109 remained at the inoculation level of 106 cfu g−1 during ripening. Lactobacillus sakei S15 as mono-culture showed higher TBARS values compared to other strains. The control group had the lowest L* value and autochthonous strains caused no significant difference for a* value. According to principal component analysis results, most volatile compounds were positively correlated with the group containing only L. sakei S15.
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- MakaleYalnız künye2022Scopus SJRQ1Changes of some bioactive and physicochemical properties during the black tea processing
Balaban, Osman Tolga; Kamiloğlu, Aybike; Kara, Hasan Hüseyin
Abstract: In this research, some physical and bioactive properties of tea samples collected from every processing stage of black tea production were investigated. The processing stages were significantly effective on the investigated properties (moisture content, color parameters [L*, a*, and b*], and pH values the total phenolic substance, antioxidant activity) (p < 0.01). The antioxidant activities were found to be at a high level in fresh tea but decreased during the processing stages. Furthermore, the lowest activity was observed in the drying stage for extracts prepared with water and in the drying and sorting stages for extracts prepared with ethanol. In addition, it was determined that palmitic acid, myristic acid, and capric acid as saturated fatty acids, oleic acid, heptadecenoic acid, and eicosenoic acid as unsaturated fatty acids formed the fatty acid profile. Palmitic acid was determined to be the dominant fatty acid in tea samples. Practical Application: Tea is a beverage known to have positive health effects. The chemical structure of tea is very effective in providing these positive effects on health. Black tea production takes place in five stages in general terms (withering, rolling, oxidation, drying, and sorting stages) after the harvesting. These processes are very effective in the quality properties of tea. This research provides information about effects of processing stages on black tea. Our results demonstrate that processing was significantly effective on the physicochemical and bioactive properties of tea. Functionality of bioactive compounds could be maintained by optimization of the applied processes.
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- MakaleAçık Erişim2021Scopus SJRQ3Validity and reliability of the Turkish version of the insomnia catastrophizing scale
Kabadayi, Fedai; Mercan, Oğuz; Yazici-Kabadayi, Sema; Elhatip, Yaser Emir; Büyüksevindik, Baki
Insomnia catastrophizing has attracted attention in recent years. Individuals may have started to recognize the importance of evaluating the consequences of insomnia, which has worsened during the coronavirus disease 2019 (COVID-19) pandemic. The present study aimed to test the validity and reliability of the Insomnia Catastrophizing Scale (ICS) in the Turkish young adult population. The study group consisted of a total of 387 participants: 57 in the pilot study and 330 in the main study. The majority of the participants in the study were females. According to the results of the confirmatory factor analysis, the single-factor structures of the ICS nighttime and daytime forms were confirmed to be the same as in the original structure, and the fit indices were above the acceptable limits. The ICS forms had very high reliability. The findings of the present study showed that the Turkish daytime and nighttime forms of the ICS are valid and reliable instruments. The results provide a means of measuring insomnia catastrophizing for use in therapeutic and counseling settings for Turkish young adult population. We also propose that mental health practitioners should design interventions to reduce insomnia catastrophizing in Turkish culture.
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- MakaleAçık Erişim2021Scopus SJRQ1Parameter Retrieval of Samples on a Substrate from Reflection-Only Waveguide Measurements
Hasar, Ugur Cem; Ozturk, Hamdullah; Kaya, Yunus; Izginli, Mucahit; Ertugrul, Mehmet
A microwave method has been proposed for constitutive parameters' extraction of samples on a known substrate. The advantage of this method is that it relies on noniterative reflection-only (air-and metal-backed) scattering (S-) parameters so that it is a good candidate for the characterization of samples when only one-port measurements are available. It is validated by the X-band (8.2-12.4 GHz) waveguide S-parameter measurements. A sensitivity analysis is followed to evaluate and improve the performance of our method.
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- MakaleAçık Erişim2020Scopus SJRQ3Effects of lactobacillus reuteri e81 added into rations of chukar partridges (Alectoris chukar) fed under heat stress conditions on fattening performance and meat quality
Tekce, Emre; Bayraktar, B.; Aksakal, V.; Dertli, E.; Kamiloğlu, A.; Çinar, K.; Takma, Ç.; Kaya, H.; Gül, M.
This study investigated the effects of the addition of Lactobacillus reuteri E81 (LRE) into rations of chukar partridges (Alectoris chukar) fed under heat stress (HS) conditions on fattening performance and meat quality. This study included 256 chukar partridges aged 1 day. The study comprised an adaptation period of 7 days and a fattening period of 35 days and included 8 different groups with 32 animals in each group. Each group was further divided into four subgroups with eight animals in each subgroup. At the end of the study, the best results in terms of fattening performance in the non-HS groups were obtained in the LRE 600 ppm group and in the HS groups, SLRE 200 ppm had the best effect on average live weight and average live weight increase, whereas SLRE 400 ppm had the best effect on FCR (p<0.05). The analysis of the samples collected from chukar partridges on day 21 showed that, there was no effect on the colour parameters and Thiobarbituric acid reactive substances (TBARS) level in the LRE in the HS and non-HS groups, whereas the meat pH level decreased in the SLRE 400 ppm group (p<0.05). The analysis of the samples collected on day 42 showed that there was no effect on colour parameters in the HS and non-HS groups. TBARS level decreased at the dose of LRE 200 ppm in the non-HS group, and the meat pH level decreased in both HS and non-HS groups (p<0.05).
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- MakaleYalnız künye2022Scopus SJRQ3High-Intensity Interval Training with Cycling and Calisthenics: Effects on Aerobic Endurance, Critical Power, Sprint and Maximal Strength Performance in Sedentary Males
Kul, Murat; Turkmen, Mutlu; Yildirim, Umit; Ceylan, Ramazan; Sipal, Onur; Cabuk, Refik; Akova, Abdullah; Aksoy, Omer Faruk; Adatepe, Eda
TABATA protocol is considered to be one of the most effective strategies among high-intensity interval training (HIIT) methods. A limited number of studies have compared the chronic effects of cycling-based and calistenic HIIT in TABATA-type. The aim of this study was to compare the chronic effects of a 8-week TABATA-type calisthenic high-intensity interval and high-intensity interval in cycling on aerobic endurance, sprint and maximal strength performance in sedentary men. 17 sedentary males participated in our study. Participants were randomly divided into calisthenic HIIT (n=9) and cycling HIIT (n=8) groups. Training groups were given 3-sessions of exercise per week on non-consecutive days for 8 weeks. Before and after the 8-week training, the body mass, body mass index, fat percentage, 30-m sprint, 1-repetition maximal strength, aerobic power and critical power levels of the participants were determined. No statistically significant different was observed in body mass (p=0.917), body mass index (p=0.928), and body fat ratio (p=0.980) in both training groups. However, both training groups achieved statistically significant improvements in peak power output (p=0.017), maximal oxygen consumption (p=0.040) and critical power (p=0.048), and there was no significant difference in the level of improvement between the groups (p>0.05). There was no statistically significant difference in 1 repetition maximal strength and sprint values of both training groups (p<0.05). TABATA type HIIT performed calistenic provides chronic effects similar to that of interval cycling form.
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- MakaleAçık Erişim2022Scopus SJRQ3A Two-Stage ORC Integration to an Existing Fluidized Bed Sewage Sludge Incineration Plant for Power Production in the Scope of Waste-to-Energy
Abusoglu, A.; Tozlu, A.; Anvari-Moghaddam, A.
This paper presents the design, evaluation, and optimization of an electricity generation system based on the two-stage organic Rankine cycle (TS-ORC), which utilizes the waste heat of an existing fluidized bed sewage sludge incineration (FBSSI) facility. The facility incinerates an average of 300 tons per day of sewage sludge with a dry matter content of 22%. After the drying process, the sewage sludge is burned in a fluidized bed combustor, and exhaust gas at a temperature of about 850-900ºC is released due to the combustion. The system provides the energy required to dry the sludge from this exhaust gas. In this study, a TS-ORC is designed to be coupled to the exhaust gas flowlines discharged to the atmosphere at two different points in the FBSSI plant. The exergy efficiency of the FBSSI facility is found to be 70.5%. Three different working fluids are selected to examine the variations of thermodynamic and thermoeconomic performance parameters of the designed TS-ORC system. The highest power generation in the TS-ORC system (183.40 kW) is achieved using R1234yf as working fluid. R1234yf is also the most expensive fluid for electricity generation among the other working fluids (10.57 $/h). The least electricity generation in the TS-ORC (142.70 kW) occurs at the thermoeconomically most affordable cost with R245fa (9.35 $/h).
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- MakaleAçık Erişim2021Scopus SJRQ3Optimization of Extraction Parameters of Ethanol Extracts of Propolis Samples Using Artificial Neural Network and Moth-Flame Optimization Algorithm
Gurgen, Ayşenur; Serencam, Huseyin; Kara, Yakup; Can, Zehra; Ylldlz, Sibel
In this study, the optimum values of propolis ethanol extracts parameters were determined with the use of single and multi-objective optimization procedures. The euclidean distance approach was used in the multi-objective optimization process. Firstly, propolis was extracted using water with ethanol contents 40, 50, 60, 70 and 80% for 8, 10, 12, 16, 20 and 24 h. Then, total phenolic content (TPC) and ferric reducing antioxidant power (FRAP) activities of all extracts were determined. With the obtained data a prediction model was produced with the use of artificial neural networks (ANN), and optimization was performed using a moth-flame (MFO) algorithm. The best prediction models for the TPC and FRAP were observed in 2-5-1 and 2-5-1 network architecture with the mean absolute percentage error (MAPE) values, 5.126 and 2.451%, respectively. For maximum TPC, the extraction parameters were determined as ethanol content 57.5% and extraction time 13.56 h. To maximize FRAP, the optimized extraction parameters were ethanol content 72.03% and extraction time 18.04 h. The optimum extraction conditions for both maximum values of the studied assays were ethanol content 70.03% and extraction time 16.93 h. The study concluded that the integrated ANN and MFO algorithm system can be used in single and multi-objective optimization of extraction parameters. The established optimization model can save time, money, labor and energy.
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- MakaleAçık Erişim2020Scopus SJRQ3The impact of dietary tarragon (Artemisia dracunculus) on serum apelin, brain-derived neurotrophic factor, cardiac troponin concentrations and histopathology of liver tissue in laying hens housed at different stocking densities
Bayraktar, Bulent; Tekce, Emre; Kaya, Hacer; Karaalp, Musa; Turunc, Eylul
Due to its association with several other stress factors (poultry house gases, inadequate ventilation, heat, cold and poor hygiene), the high stocking density is a major stress factor that adversely affects the health and performance of poultry and the quality of the poultry products. Therefore, this experimental study was aimed at analysing the impact of different doses of dietary tarragon (Artemisia dracunculus) on the serum apelin, plasma brain-derived neurotrophic factor (p-BDNF), and cardiac troponin I (cTnI) concentrations, and the correlation between these indicators in laying hens housed at different stocking densities. The aim of this study is to investigate the effects of adding tarragon in different ratios to laying hen rations in the 2ndovulation period on the cTnI, apelin, and BDNF hormone concentrations and the liver histopathology. The experiment was carried out over a period of eight weeks, with 192 Lohman Brown commercial hybrids at 50 weeks of age. Eight groups (four replicates each), composed of laying hens of equal body weight, which were housed at stocking densities of 580 cm2/hen and 810 cm2/hen and received 0, 1, 5 and 10 mmol/kg of tarragon (Artemisia dracunculus) in the feed, were established. At the end of the trial, 96 of the housed egg-laying hens (3 birds in each subgroup, a total of 12 birds in each group) were randomly selected and blood samples were taken from the vena subcutanea ulnaris. The samples collected were analysed for the apelin, p-BDNF, and cTnI contents. The analysis results demonstrated that tarragon supplementation had no effect on the serum apelin, p-BDNF and cTnI concentrations (P > 0.05). The Sub-Groups ST1, ST1.2, and ST6 presented with severe hyperaemia of the sinusoidal, portal and acinar blood vessels, whilst the hyperaemia of these blood vessels was moderate in Sub-Group ST12. Apelin, BDNF, and cTnI can act as protective factors against negative consequences of stress (e.g., stocking density or heat stress).
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- MakaleAçık Erişim2021Scopus SJRQ2Effect of ohmic heating on ultrasound extraction of phenolic compounds from cornelian cherry (Cornus mas)
Kutlu, Naciye; Isci, Asli; Sakiyan, Ozge; Yilmaz, Asim Egemen
In this study, total phenolic compounds (TPCs) from cornelian cherry were extracted by using maceration (ME), ultrasound extraction (UE), and ohmic heating-assisted ultrasound extraction (OAUE) methods. ME was used as a control group. It was observed that the ultrasound was effective on the yield of TPC in extraction and the effect was increased when this method was supported with ohmic heating (OH). The maximum TPC extracted was found to be 7.52 mg GAE/g dry matter (by using OAUE) which was 13% and 37% higher compared with that of obtained by UE and ME, respectively. It was also observed that the ohmic heating application decreased the extraction time by about 34% compared with UE. Moreover, the extracts obtained by OAUE had the highest total monomeric anthocyanin concentration and antioxidant activity. Consequently, the OH application prior to extraction played an active role in both obtaining the valuable compounds and decreasing the extraction time. Practical applications: Cornelian cherry (Cornus mas), which is a natural antioxidant source, contains a significant number of valuable compounds (polyphenols, vitamins, minerals, etc.). Therefore, new extraction methods were used as an alternative to conventional methods (such as maceration) to extract the valuable compounds. It was observed that novel methods such as ultrasound and ohmic heating-assisted extraction had a positive effect to increase extraction yield and saving time. Highly efficient applications (such as ohmic heating) on the extraction of bioactive compounds from food materials open up a new horizon in the food industry.
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- MakaleAçık Erişim2021Scopus SJRQ4Investigation of the relationship of asprosin and cardiac troponin response with some physiological and biochemical parameters in Anatolian native horse
Bayraktar, Bülent; Tekce, Emre
Summary: Asprosin is a recently discovered glucogenic hormone released from starvation-induced white adipose tissue and amongst others it protects against hyperinsulinism associated with metabolic syndrome. The aim of this study was to examine the effect of age, gender and season on metabolic (asprosin) and cardiovascular (cardiac troponin, I (cTnI), CK, CK-MB) function markers and their relationship with some biochemical parameters in Anatolian native horse breed. This study was carried out between February–August 2020. A total of 40 horses was used for this purpose, including 20 mares and 20 stallions in the age range of 1–6, 7–12. Serum asprosin level, for the winter season in stallions and mares aged 1–6 and 7–12 years respectively 8.9, 8.36; 14.08, 13.58ng/ml were as determined. In addition, for the summer season respectively 17.98, 18.68; 22.22, 21.32ng/ml were detected and no difference between the groups (P>0.05). On the other hand, serum cTnI levels for the winter season in stallions and mares aged 1–6 and 7–12 years respectively 0.014, 0.018; 0.016, 0.02ng/ml were as determined. In addition, for the summer season respectively 0.012, 0.016; 0.014, 0.018ng/ml were detected. It was shown that the serum biochemical parameters and levels of cTnI levels in the domestic horse breed the horses belonging to the Anatolian varied depending on age, gender, and season (p < 0.05) but the effect of hormone levels serum asprosin wasn’t found statistically significant (p>0.05).Our results showed that cTnI could be a useful parameter in the examination of the cardiovascular system status of horses.
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- MakaleAçık Erişim2021Scopus SJRQ1Prediction of water-adulteration within honey by air-line de-embedding waveguide measurements
Hasar, Hafize; Hasar, Ugur Cem; Kaya, Yunus; Ozturk, Hamdullah; Izginli, Mucahit; Ozbek, Ibrahim Yucel; Oztas, Taskin; Canbolat, Mustafa Yildirim; Ertugrul, Mehmet
An efficient de-embedding air-line microwave method has been proposed for accurate relative complex permittivity, εr=εr′−iεr′′, measurement of water-adulteration level within honey. It could be effectively applied to eliminate the errors arising from usage of imperfect calibration standards because it bypasses the requirement of these standards. Its accuracy is improved by utilizing the unitary and similarity properties of a passive two-port network, and then is compared with the accuracy of a calibration-dependent method present in the literature by using normalized root-mean-square-error (N-RMSE) values of εr′ and εr′′ of distilled water, in reference to the Debye value. From this comparison, it is observed that N-RMSE values calculated for εr′ (and εr′′) by using this calibration-dependent method and the (improved) proposed method are, respectively, around 0.1955 (0.1002) and 0.1962 (1.1067), indicating a good agreement between them. After validation the proposed de-embedding method using distilled water measurements, tested pure honey was adulterated with distilled water by different percentage values δ ranging from 1% to 10% in 1% increments. It is observed that the maximum distance between extracted εr′ (or εr′′) values of adulterated honey by the applied calibration-dependent method and the proposed method is less than 2%. Afterward, an empirical formula was devised to fit εr′ and εr′′ values from measured εr of water-adulterated honey with various δ levels. It is noted that extracted εr′ is much more better fitted than extracted εr′′, especially for δ≤4. Next, an optimization process is followed to evaluate the frequency for optimum prediction of adulteration levels using the empirical formula based on εr′ or εr′′. It is noticed that optimized δ values using the empirical formula based on εr′ (with an average prediction error of around 0.071 at 4.5 GHz) are superior to optimized δ values using the empirical formula based on εr′′ (with an average prediction error of around 0.085 at 4.2 GHz) for prediction of previously known δ values. Sensitivity and uncertainty analyses were performed to assess and improve the accuracy of the proposed method.
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- MakaleYalnız künye2022Scopus SJRQ2Investigation of the effect of the addition of grain refiner and modifier addition on wear properties in sand and permanent mould casting of A357 and A380 aluminium alloys
Çolak, Murat; Arslan, İbrahim
The aim of this study is to improve the tribological behaviour of aluminium alloys by using grain refiner and modifier. The effects of Al5Ti1B grain refiner and Al10Sr modifier additives on friction and wear properties on A380, A357 alloys produced by pouring sand andpermanent mould casting were investigated. Abrasion tests were carried out under dry conditions against St1040 steel disc using a pin-disk system with 20 N load and 1.0 m/s sliding speed. It was determined that grain refiner and modifier additives decrease the friction coefficient and increase the wear resistance. It was determined that the samples produced by permanent mould casting method decreased the friction resistance by 9% and the abrasion resistance increased by 40% compared to the samples produced in sand mould. The lowest wear rate was obtained in A380 alloy with TiB and Sr added with a value of 4.87 × 10–11 m2/N.
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- MakaleAçık Erişim2022Scopus SJRQ2Investigation of the biological treatability of pistachio processing industry wastewaters in a batch-operated aerobic bioreactor
Tırınk, Sevtap; Nuhoğlu, Alper; Kul, Sinan
This study encompasses investigation of treatment of pistachio processing industry wastewaters in a batch reactor under aerobic conditions, calculation of kinetic parameters and comparison of different inhibition models. The mixed microorganism culture used in the study was adapted to pistachio processing industry wastewaters for nearly one month and then concentrations from 50 to 1000 mg L−1 of pistachio processing industry wastewaters were added to the medium and treatment was investigated in batch experiments. The Andrews, Han-Levenspiel, Luong and Aiba biokinetic equations were chosen for the correlations between the concentration of pistachio processing industry wastewaters and specific growth rates, and the kinetic parameters in these biokinetic equations were calculated. The maximum specific growh rate, semi-saturated constant and inhibition constant parameters, included in the Aiba biokinetic equation providing best fit among the other equations, had values calculated as 0.25 h−1, 19 mg L−1, and 516 mg L−1, respectively. The substrate value reaches maximum value and the specific growth rate at this concentration were calculated as 101.379 mg L−1 and 0.1827 h−1, respectively. Graphical abstract: [Figure not available: see fulltext.]
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- MakaleAçık Erişim2022Scopus SJRQ1Simultaneous Detection of Ochratoxin A and Aflatoxins in Industrial and Traditional Red and isot Pepper Flakes along with Dietary Exposure Risk Assessment
Oztekin, Sebahat; Karbancioglu-Guler, Funda
This study focused on the co-occurrence of aflatoxins (AFs) and ochratoxin A (OTA) in traditionally and industrially dried red pepper flakes (DRPFs) and isot pepper flakes (IPFs). Following the multitoxin immunoaffinity column (IAC) clean-up, high-performance liquid chromatography coupled with fluorescence detection (HPLC-FLD) was used to quantify AFs and OTA. The limit of detection (LOD) and limit of quantification (LOQ) values were 0.11 and 0.18 μg kg-1(AFB1), 0.04 and 0.08 μg kg-1(AFB2), 0.13 and 0.18 μg kg-1(AFG1), 0.04 and 0.11 μg kg-1(AFG2), and 0.10 and 0.21 μg kg-1(OTA), respectively. AFB1,AFB2, AFG1, and OTA were found to be positive in 93, 74, 17, and 94% of all samples, respectively. The contamination levels in positive samples ranged from 0.23 to 38.69, 0.04 to 2.14, 0.13 to 0.88, and 0.18 to 52.19 μg kg-1for AFB1, AFB2, AFG1, and OTA, respectively, while no AFG2was found above the detection limit (0.04 μg kg-1). None of the industrial isot peppers exceeded the European Union limits, while the levels of AFB1(5 μg kg-1), total AFs (10 μg kg-1), and OTA (20 μg kg-1) of the traditional peppers were above the limit by 30% (16/54), 26% (14/54), and 4% (2/54), respectively. Co-occurrence of AFB1-AFB2-OTA was the most frequent, accounting for 54% (29/54) of all samples. At the upper bound (UB), estimated average exposure to AFB1, total AFs, and OTA was determined to be 0.175, 0.189, and 0.124 ng kg-1bw day-1in all samples, respectively. The margin of exposure (MoE) value of AFB1and total AFs was found to be 977 and 909, indicating high health concerns compared to OTA (MoE >10,000). AFB1and total AFs may result in 0.0058 and 0.0062 liver cancer cases/100,000 person/year at UB, respectively, and weekly OTA exposure was 0.868 ng kg-1bw, well below the provisional tolerable weekly intake, hence not of health concern. AFs exposure could endanger health, whereas OTA posed no toxicological concerns through dried red pepper consumption.
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- MakaleAçık Erişim2019Scopus SJRQ1Piezoelectric and electromagnetic hybrid energy harvesting with low-frequency vibrations of an aerodynamic profile under the air effect
Bolat, Fevzi Cakmak; Basaran, S.; Sivrioglu, S.
In this study, a novel hybrid energy harvesting system consisting of a piezoelectric material and an electromagnetic induction device is experimentally inevstigated. Flow-induced vibrations can be considered as an aerodynamics air effect and can be converted to electrical energy. By connecting an airfoil profile to a beam element, vibrations are occurred on the proposed structure by creating an aerodynamic air effect. This aerodynamic air effect is controlled by using an Arduino board with a solenoid valve connected to the air line. A piezoelectric transduction is attached on the beam, and an electromagnetic-Lorentz induction is connected to the airfoil element at the end of this beam. Energy is simultaneously harvested by using electromagnetic induction and piezoelectric transduction with respect to the vibration motion of the beam. Within the scope of the study, the amount of energy obtained using the piezoelectric material and Lorentz actuator by connecting resistors of different sizes are measured with an oscilloscope. The experimental results show that the amount of energy obtained from the proposed structure is at promising levels that can be used to run small electronic units which commonly used in aerospace applications.
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- MakaleYalnız künye2019Scopus SJRQ3Biocatalyzed Enantiomerically Pure Production of (S)-Phenyl(thiophen-2-yl)methanol
Şahin, Engin; Dertli, Enes
Chiral aryl heteroaryl methanols are important precursors for the synthesis of pharmaceutically important molecules. The aims of this study were to use a biocatalyst that could efficiently bioreduce phenyl(thiophen2- yl) methanone 1 to (S)-phenyl(thiophen-2-yl) methanol 2, to identify the impact of the physicochemical factors that might affect the bioreduction by the biocatalyst, and to obtain multigram production of aryl heteroaryl secondary alcohol 2 with the biocatalyst under optimized conditions. Over the years, the (S)phenyl( thiophen-2-yl) methanol was synthesized on a small scale using a chemical catalyst without its enantiomerically pure form. In this study, Lactobacillus paracasei BD101 was used for the asymmetric reduction of phenyl(thiophen-2-yl) methanone to (S)-phenyl(thiophen-2-yl) methanol in the large-scale production. The asymmetric bioreduction conditions were systematically optimized, and the production of 3.77 g of (S)-phenyl(thiophen-2-yl) methanol was carried out in enantiomerically pure form > 99% enantiomeric excess (ee), > 99% conversion, and 90% yield. This method obtained with this biocatalyst is a process that can be used industrially in terms of conversion, ee, and yield. This study provides guidance for the application of L. paracasei BD101 in the production of optically active aryl heteroaryl alcohols.
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- MakaleAçık Erişim2021Scopus SJRQ2Gamma-ray irradiation effects on capacitance and conductance of graphene-based Schottky diode
Efil Kutluoğlu, Esra; Öz Orhan, Elif; Bayram, Özkan; Bilge Ocak, Sema
The purpose of this study is to determine the effects of gamma (γ)-ray irradiation on capacitance and conductance features of Al/Graphene/Al2O3/p-Si structure. Graphene has been grown on copper foil by the Chemical Vapor Deposition (CVD) method and transferred onto Al2O3/p-Si by the wet transfer method. After Al/Graphene/Al2O3/p-Si structure has been exposed to 30 kGy and 60 kGy γ-ray irradiation, capacitance, and conductance measurements have been accomplished at 300 K. Electrical parameters have been compared before and after γ-ray irradiation for 50 kHz and 500 kHz. These results have been confirmed that capacitance and conductance values have increased after γ-ray irradiation and, have decreased when the radiation dose was increased from 30 kGy to 60 kGy. It has been observed that series resistance has decreased after 30 kGy radiation dose and has increased with increasing radiation dose.
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- MakaleAçık Erişim2021Scopus SJRQ1Extraction of Phenolic Compounds from Cornelian Cherry (Cornus mas L.) Using Microwave and Ohmic Heating Assisted Microwave Methods
Kutlu, Naciye; Isci, Asli; Sakiyan, Ozge; Yilmaz, Asim Egemen
In this study, it was aimed to extract bioactive compounds (phenolics and anthocyanins) from cornelian cherry (Cornus mas L.) using microwave (ME) and ohmic heating assisted microwave extraction (OH-ME) as an alternative to maceration (M). Total phenolic compound (TPC), total monomeric anthocyanin content (TMAC), antioxidant activity (AA), water-soluble solid matter (WSSM), color values, and pH of the extracts were determined. The effect of extraction time, solid to solvent ratio, microwave power, electrical field strength, and holding time during ohmic heating on extraction characteristics was investigated for different methods. Ohmic heating application prior to extraction has enhanced the TPC yield by 1.1 and 5.4-folds compared to that of ME and M, respectively. Moreover, the extraction time was decreased by approximately 42 and 95% as regards ME and M, respectively. The highest TMAC value (0.65 mg cya-3-glu/g dry matter) was observed with OH-ME. The experimental data obtained by ME and OH-ME methods was fitted to the Peleg model to describe the TPC yields. These results indicate that the combined application of ohmic heating and microwave extraction is a potential alternative method for total phenolic compounds extraction from cornelian cherry due to increased yields and reduced extraction times.
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