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  • MakaleYayıncıda açık erişim2026
    Exploring the role of rare earth elements doped TiO₂ based photoanodes on the performance of dye-sensitized solar cells

    Caliskan, Berrak; Sayan, Enes; Igman, Erdal

    This study investigates the synthesis and characterization of rare earth elements (REEs) doped TiO₂ thin films based photoanodes for use in dye-sensitized solar cells (DSSCs). For this purpose, TiO₂ films were doped with Ho³⁺, La³⁺, Er³⁺, and Yb³⁺ ions to enhance photoelectrochemical properties. Characterization techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM), UV-Vis spectroscopy, BET surface area analysis, and X-ray photoelectron spectroscopy (XPS) were employed for the structural, morphological, and optical characterization of the synthesized photoanodes and CEs. REEs doping improved the surface morphology and optical properties of TiO₂, in particular, it increased photon absorption in the visible light range. La³⁺ and Ho³⁺ significantly improved photovoltaic performance, achieving power conversion efficiencies of 3.78% and 2.87%, respectively, compared to that of pure TiO₂. These enhancements indicate improved charge transport and light harvesting due to incorporation of REEs. Additionally, replacing the conventional platinum counter electrode (CE) with reduced graphene oxide (rGO) further enhanced performance, offering a low-cost and efficient alternative. The study highlights the combined benefits of REEs doping and rGO integration in improving DSSCs efficiency. These findings contribute to the development of more sustainable, cost-effective solar energy technologies and underline the potential of REEs-doped TiO₂ films and rGO electrodes in advancing next-generation photovoltaic devices.

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  • MakaleYalnız künye2026
    Comparative investigation of composite-metal lap joints with mono-adhesive and thermoplastic-reinforced mixed adhesive at elevated temperatures

    Erbayrak, Engin; Eker, Beril; Colak, Murat

    This study primarily examines the strength of a single lap joint having a mixed adhesive overlap consisting of a single adhesive and its thermoplastic reinforced state under varying temperatures. In the single lap joint, Titanium-Boron reinforced A356 aluminum was employed as the metal adherend, while plain woven glass fiber-reinforced epoxy (GFRE) was employed as the composite adherend. In the application of the mixed adhesive overlap, the brittle adhesives were employed in the middle section of the lap joint, while the reinforcement of the thermoplastics was employed on the adhesives at both sides of the lap joint. The single lap joints were subjected to tensile tests at 1 mm/min loading rates under room temperature and 120 °C, which is the melting point of the copolyester. In the numerical analysis, the cohesive zone model was applied in order to define the adhesives; however, elastic isotropic and orthotropic material behaviors were employed for the metal and composite adherends, respectively. Eventually, it is determined that the strength of a mixed adhesive lap joint consisting of a single adhesive and its thermoplastic reinforced state is better than a lap joint made with the mono-adhesive alone. Although literature suggests that mixed adhesive overlaps can be formed using at least two different adhesives (one ductile and one brittle), this study demonstrated that a mixed adhesive zone can be created using a single adhesive and thermoplastic reinforcement.

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  • MakaleYalnız künye2026
    Policy factors affecting international sporting success in Turkey from the perspective of the SPLISS model

    Ersöz, G.; Kan, M.E.; Yenilmez, M. Ince; Kantar, G.

    In recent years, research on elite sport policies has mainly focused on systems in Europe, North America and Australia. This study represents the first qualitative analysis of Turkey within the framework of the SPLISS model, aiming to fill the regional gap in the literature and offer original contributions regarding the model’s cultural and structural adaptability. In this context, the study aims to analyse the policy factors affecting international sporting success in Turkey. A total of 15 individuals–five athletes, five coaches and five sports managers–aged between 21 and 51 and actively involved in sport, participated in the study. A semi-structured interview technique was used, with questions prepared from the SPLISS model perspective, and the data were analysed using content analysis. The findings reveal that financial support for sport in Turkey is inadequate, there is no merit-based system in sports governance, the limited hours and content of physical education classes in schools reduce participation in sport, career support for athletes is insufficient, talent identification projects are dysfunctional, coach education has significant shortcomings and there is a lack of collaboration between sport science researchers and practitioners. The study indicates that Turkey’s sports policies require comprehensive restructuring through reforms in several areas, including equitable financial support, merit-based governance, enhanced collaboration and coordination among sport institutions, long-term strategic planning, strengthening school-based sport, sustainable career support for athletes and fostering stronger cooperation between researchers and practitioners in sport sciences.

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  • MakaleYalnız künye2026
    Development and characterization of postbiotic-enriched biodegradable films with antifungal activity for tomato storage

    Kaya, Yasemin; İspirli, Hümeyra; Bozkurt, Fatih; Sağdıç, Osman; Şengül, Mustafa; Dertli, Enes

    BACKGROUND: One of the major contributors to postharvest losses in tomatoes is the development of infectious mold diseases. In this study, four distinct biodegradable film formulations were developed incorporating postbiotics derived from Lactiplantibacillus plantarum Y48 and the polysaccharide alternan. The formulations included alternan, sodium alginate and glycerol (AAG), alternan, postbiotic, sodium alginate and glycerol (APAG), postbiotic, sodium alginate and glycerol (PAG), and sodium alginate and glycerol (AG) as a control. The films were characterized in terms of their physical, mechanical, thermal, and morphological properties. To assess antifungal efficacy, tomatoes artificially inoculated with Alternaria alternata were coated with each film and stored at ambient temperature for 8 days. RESULTS: The incorporation of alternan and postbiotics enhanced both the mechanical strength and thermal stability of the films. Fourier-transform infrared (FTIR) analysis confirmed the successful integration of the bioactive components into the polymer matrix. Scanning electron microscopy (SEM) imaging revealed that postbiotic addition contributed to a rougher and more rigid surface morphology, while alternan improved the structural cohesion of the films. All film formulations exhibited significant inhibitory effects against A. alternata, with the PAG formulation demonstrating the most pronounced antifungal activity. CONCLUSION: These results suggest that the PAG film, enriched with postbiotics, represents a promising biocontrol strategy for mitigating fungal spoilage in tomatoes. In conclusion, this study underscores the potential of combining postbiotics and alternan for the development of active, biodegradable edible films with antifungal functionality for postharvest preservation.

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  • MakaleYayıncıda açık erişim2026
    A NIKOM-Based Conceptual Framework for Spiritual Counseling Services in Turkey: Toward an Intervention Model

    Çinici, Murat

    Spiritual counseling has expanded rapidly in Turkiye over the past two decades. Hospitals, prisons, family guidance offices, eldercare facilities, disaster-response systems, and addiction recovery programs now host spiritual counselors as part of routine care. The methodological foundation of these services, however, remains underdeveloped. Using a conceptual review and theoretical integration approach, this article proposes—but does not empirically test—a framework that links spiritual counseling practice in Turkiye to the Intention Code Model (NIKOM), a recently formulated cognitive model that conceptualizes mental life through if–then schemas (codes), their activation, and their alignment with bodily systems. The article reviews the institutional landscape of spiritual counseling in Turkiye, situates NIKOM among adjacent cognitive models, and shows how core Islamic concepts—tawakkul, ṣabr, shukr, tawba, and dhikr—can be interpreted as functions relevant to counseling practice. A standardized five-stage intervention template is proposed and applied to six service domains. The article closes by offering five testable propositions, considering ethical limits, and articulating concrete referral criteria. The proposed framework is theoretically grounded and empirically testable; clinical efficacy is not claimed.

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  • MakaleYalnız künye2026
    Enhanced freshwater production in prism-type solar stills using a fresnel lens system with comprehensive energy-exergy and cost analysis

    Ceviz, Mehmet Akif; Köksal, Hüseyin; Afshari, Faraz; Muratçobanoğlu, Burak

    This study presents the development and performance evaluation of a novel prism-type solar still integrated with a Fresnel lens concentration system designed to concentrate solar radiation on an external spiral heat exchanger. Experimental investigations were conducted under two different saline water flow rates of 0.05 and 0.1 kg/min. The performance of system was comprehensively analyzed in terms of fresh water yield, thermal efficiency, exergy efficiency, and economic viability. The heated saline water and resultant vapor were directed into the prism-shaped condensation chamber, where condensation occurred efficiently. The experimental results demonstrated that lower saline water flow rates led to higher water temperatures and enhanced evaporation rates, thereby increasing freshwater productivity. In contrast, higher flow rates resulted in greater accumulation of saline water within the basin, reducing the evaporation rate and thus lowering overall productivity. The proposed design uniquely combines geometric enhancement via a prism-shaped condensation chamber with solar concentration through a Fresnel lens, enabling a dual-effect improvement in energy absorption and condensation efficiency, an approach not previously reported in the literature for solar desalination systems. The system achieved thermal and exergy efficiencies of 22.95 and 15.50%, respectively, at a saline water flow rate of 0.05 kg/min, producing 92 g of clean water in 60 min. Furthermore, the cost analysis conducted indicated a cost of $0.2546 per liter for this scenario.

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  • MakaleYayıncıda açık erişim2026
    Climate-driven synchronization of honey bee flight activity and plant phenology in Türkiye: development of a Beekeeping Climate Suitability Index (BCSI)

    Erdoğan, Yaşar; Erdoğan, Ümmügülsüm

    Honey bees (Apis mellifera L.) provide essential pollination services that depend on the temporal synchronization between flight activity and plant flowering phenology, both strongly influenced by climatic conditions. However, this relationship remains insufficiently quantified at large spatial and temporal scales. In this study, we quantified climate-driven honey bee flight activity and its alignment with flowering phenology of major nectar plants in Türkiye using ERA5-Land data for the period 1981–2023. Suitable flight days were defined based on temperature (≥12°C) and precipitation (0 mm), and seasonal suitability was evaluated at a monthly scale. A composite Beekeeping Climate Suitability Index (BCSI) was developed by integrating flight activity, flowering overlap and nectar flow window. The number of suitable flight periods ranged between 4 and 7 months (mean ≈5.5), indicating substantial interannual variability. Flight flowering synchrony was low for early-spring species (23–35%) but reached 100% for summer species. BCSI values ranged from 0.44 to 1.00, capturing variability in climatic suitability for beekeeping. These findings demonstrate that climatic variability plays a decisive role in shaping bee plant interactions and provide a quantitative basis for climate-informed beekeeping management.

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  • MakaleYalnız künye2026
    Sorting chiral active Brownian particles with radially modulated optical fields

    Yücel, Harun

    This study presents a numerical investigation of sorting chiral active Brownian particles using radially modulated optical fields. How these factors affect particle trajectories and spatial distributions is examined by systematically varying particle parameters such as self-propulsion speed, angular velocity, and optical fringe modulation. It is found that the average orbit radius of the particle trajectory strongly depends on the ratio of the self-propulsion speed to the average velocity induced by the moving fringe pattern. In particular, the average orbit radius converges to the theoretical orbit radius defined by the ratio of the self-propulsion speed to the angular velocity in the regime where the self-propulsion speed is greater than the fringe-induced velocity. In mixtures of particles with differing chirality, the dynamic response to circular fringe patterns enables effective classification based on motility. These findings suggest that structured light fields can be used to manipulate and selectively sort chiral active particles, which have potential applications in optical micromanipulation and active matter research.

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  • MakaleYalnız künye2026
    How to conceptualize the equal sign by middle school students?

    Türk, Adem; Öztürk, Mesut

    This research examined middle school grade 5–8 students’ conceptualization of the equal sign. The study employed a cross-sectional approach. Eight middle school students studying in official public schools in Turkey participated in the study. The study’s data were collected through a clinical interview that utilized eight open-ended questions, covering topics such as arithmetic, pre-algebra, proportional relationship, and algebra. Thematic analysis was used to analyze the study data. Although previous studies showed that students saw the equal sign as write a result, the results of this research, which is a follow-up study, revealed that students did not think of the equal sign as write a result.

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  • MakaleYayıncıda açık erişim2026
    Self-Regulation and Mathematics Anxiety: The Conditional Mediating Role of Mathematical Language Self-Efficacy and Implications for Inclusive Education

    Öztürk, Mesut; Ada Yildiz, Kübra; Charitaki, Garyfalia

    In this quantitative study, we investigated the conditional mediating role of students’ mathematical language self-efficacy in the relationship between self-regulation and mathematics anxiety. The study employed a relational research design and included survey data from 706 middle school students attending public schools in Turkey. Findings indicated that both self-regulation and perceived self-efficacy in mathematical language use were significantly associated with mathematics anxiety. Moreover, the effect of self-regulation on mathematics anxiety was significantly mediated by students’ perceptions of their ability to understand and use mathematical language self-efficacy. The indirect effect was negative while the direct effect was positive, indicating a suppression (competitive mediation) effect, whereby self-regulation exerts both anxiety-reducing and potentially anxiety-inducing influences through different pathways. Conditional mediation analysis further revealed that this mediating effect varied as a function of students’ perceived academic support, with the indirect effect being non-significant for students who did not receive support. Measurement invariance across gender and grade level was examined to ensure that the constructs were measured equivalently across groups. These findings highlight the importance of fostering both self-regulation skills and mathematical language proficiency, particularly in contexts where students may lack sufficient support. These findings provide a theoretically grounded and practically relevant framework for understanding mathematics anxiety within inclusive mathematics education contexts.

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  • MakaleYayıncıda açık erişim2026
    A natural nephroprotective adjuvant for cancer chemotherapy: Rosmarinic acid disrupts IL-17 A-Ferroptosis coupling in Ifosfamide-induced renal injury

    Süzen Celbek, Büşra; Şimşek, Hasan; Akaras, Nurhan; Kandemir, Özge; Kızıl, Hamit Emre; Mutlu, Hüseyin; Kandemir, Fatih Mehmet

    Rosmarinic acid (RA) is a natural polyphenol with established pleiotropic protective effects. Ifosfamide (IFA) is a potent antineoplastic agent whose clinical utility is severely limited by dose-dependent nephrotoxicity, primarily mediated by its metabolite, chloroacetaldehyde (CAA). This study aimed to investigate whether RA protects against IFA-induced nephrotoxicity and to elucidate the underlying molecular mechanisms. Male Wistar albino rats (n = 7 per group) were allocated into four groups: Control, RA-only (50 mg/kg, p.o., 2 days), IFA-only (a single 500 mg/kg, i.p. dose), and IFA + RA. Serum biochemical markers (urea, creatinine), renal oxidative stress parameters (MDA, GSH, SOD, CAT, GPx), gene expression levels (NF-κB, TNF-α, IL-1β, IL-17 A, ACT1, TRAF6, Caspase-3, Bax, Bcl-2, PTGS2, GPX4, TfR1), and histopathological/immunohistochemical analyses (KIM-1, Nephrin, Caspase-3) were performed 24 h post-administration. IFA induced severe renal dysfunction, marked oxidative stress, and extensive histopathological damage. Mechanistically, IFA initiated a pathogenic cascade activating intrinsic apoptosis and ferroptosis, driven by a self-sustaining IL-17 A-TRAF6-NF-κB inflammatory loop. RA co-treatment (50 mg/kg) significantly reversed all functional, biochemical, and histological damage by strategically breaking this crosstalk, restoring redox homeostasis, and simultaneously restraining both cell death programs. In conclusion, RA protects against IFA nephrotoxicity by targeting the critical inflammation-ferroptosis coupling, positioning it as a highly promising adjuvant candidate for clinical use to mitigate IFA-induced renal injury.

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  • DüzeltmeYayıncıda açık erişim2026
    Correction: From screens to minds: the mediating role of psychological well-being between digital reading and AI anxiety (Frontiers in Psychology, (2025), 16, (1727759), 10.3389/fpsyg.2025.1727759)

    Özbilen, Uǧur; Banaz, Emrullah; Şahin, Tuǧrul Gökmen

    Positive Psychology Affiliation 3 “Department of Social Sciences and Turkish Language Education, Inonu University, Malatya, Türkiye” was erroneously given as “Department of Social Sciences and Turkish Language Education, Ataturk University, Erzurum, Türkiye”. The original version of this article has been updated.

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  • MakaleYalnız künye2026
    Effect of Virtual Reality Glasses on Mild Cognitive Impairment in Older Adults: A Randomized Controlled Trial

    Daştan, Buket; Ünal, Hediye

    PURPOSE: The current randomized controlled trial evaluated the effect of a virtual reality (VR) glasses intervention on mild cognitive impairment (MCI) in older adults. METHOD: This study was conducted with 24 participants (12 in the intervention group and 12 in the control group) admitted to a neurology outpatient clinic. Participants completed a descriptive information form, the Mini-Mental State Examination, and Montreal Cognitive Assessment. The intervention group watched VR videos 3 days per week for 4 weeks, whereas the control group received no intervention. RESULTS: Participants in the VR intervention group showed improvement in MCI, whereas no significant change was observed in the control group. CONCLUSION: VR interventions may serve as effective tools to enhance cognitive functions in older adults with MCI. Expanding the intervention content and tailoring applications to address specific symptoms may yield more comprehensive results.

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  • MakaleYayıncıda açık erişim2026
    Neurobiological and psychological effects of reciting the Quran from the Mushaf

    Okur, Süheyb; Bayraktar, Bülent

    Background: This study aims to examine the acute neurobiological effects of reciting the Quran from the Mushaf on salivary BDNF, Apelin, and Cortisol levels and their relationship with emotional state. Methods: The study employed a randomized pre-test post-test control group design conducted in Türkiye. The sample consisted of 100 healthy theology students (50 females, 50 males) aged 18–25, proficient in reciting the Quran in accordance with Tajweed rules. Participants were randomly assigned to either the experimental group (reciting the first nine verses of Surah Al-Imran, n = 50) or the control group (standardized passive resting, n = 50). Salivary BDNF, apelin, and cortisol levels were measured using the ELISA technique before and after the intervention. Emotional states were assessed using the Mood Scale and the Psychological Well-being Scale. Results: The experimental group exhibited a statistically significant increase in mean salivary BDNF and apelin levels and a significant decrease in cortisol levels following recitation compared to the passive control group (p < 0.05). In terms of gender, no statistically significant differences were observed in biomarker responses (p >.05). Correlation analysis revealed a significant “biological reciprocity,” where cortisol showed a negative correlation with apelin (r = -0.436, p < 0.001) and BDNF, while correlating positively with negative emotions. Conclusions: Reciting the Quran aloud acts as a rapid psychophysiological intervention that downregulates the HPA axis (reduced cortisol) and upregulates neurotrophic factors (increased BDNF and apelin). These findings suggest that structured recitation functions as a restorative neuroplasticity practice, promoting biological stress resilience associated with psychological well-being.

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  • MakaleYalnız künye2026
    Tailoring Physicochemical and Technological Properties of α-Glucans Through Mutations of GTFA from Lactobacillus Reuteri E81

    Gökcan, Hande; İspirli, Hümeyra; Dertli, Enes

    Glucansucrases catalyze the production of α-glucans using sucrose as substrate with distinct physicochemical characteristics originates from mainly the type of linkages, degree of branching and molecular mass. New forms of α-glucans can be produced by applying specific mutations to glucansucrases. In this study, a single and double mutation at Leu933 and Leu935 sites of glucansucrase E81 was applied and L933I and L933I-L935F sites modified glucansucrase was obtained. Structural characterisation of bioengineered α-glucans revealed that ratio of (1 → 3):(1 → 6) linked α-Glc units altered at L933I whereas no (1 → 3)-linked α-Glc units were presented for L933I-L935F modified glucansucrase detected by NMR analysis. Both bioengineered α-glucans had lower molecular weights in comparison to glucan E81 detected by GPC analysis. TGA and DSC analysis were applied to detect the thermal profiles of bioengineered α-glucans whereas FTIR and XRD analysis were applied to determine the alterations in the structural and physical nature of the bioengineered α-glucans, respectively. Finally, SEM and AFM analysis were applied to explore the morphological modifications of the bioengineered α-glucans. This study provides a better understanding for the potential role of final glucan structures on their physicochemical characteristics. Keywords: glucansucrase; carbohydrate engineering; mutation.

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  • MakaleYayıncıda açık erişim2026
    Dual antidepressant-like and antinociceptive effects of Hypericum olympicum extract in mice: preclinical behavioral evidence

    Saltan, Nagehan; Üçel, Umut İrfan; Göger, Fatih; Özkay, Ümide Demir; Can, Özgür Devrim

    Hypericum Tourn. ex L. species exhibit well-documented neuropsychopharmacological activities, yet the central effects of Hypericum olympicum L. remain unknown. Given the frequent comorbidity of depressive symptoms and pain, this study aimed to characterize, for the first time, the antidepressant-like and antinociceptive profile of H. olympicum in mice. A methanolic extract of the aerial parts (HoE) was prepared, and its major phenolic constituents were identified by LC-MS/MS. At behaviorally active doses, HoE (2.5 and 5 mg/kg, i.p.) did not impair motor coordination in the Rota-rod test, in contrast to diazepam (2 mg/kg, p.o.), indicating the absence of neuromotor confounding effects. In both the tail suspension test (TST) and the modified forced swim test (MFST), HoE significantly reduced immobility, with effects comparable to those of fluoxetine (30 mg/kg, p.o.). In the MFST, increased swimming behavior without changes in climbing suggested a predominantly serotonergic component. HoE also produced marked antinociceptive effects in multiple nociceptive models. It increased response latencies in the hot-plate, tail-immersion, and tail-clip tests, reflecting activity in supraspinal and spinal thermal and mechanical nociceptive processing. In addition, HoE significantly reduced acetic acid-induced writhing, indicating visceral antinociceptive activity. Morphine (10 mg/kg, i.p.) served as the positive control in pain assays. LC-MS/MS analysis indicated the presence of major phenolic constituents, including hyperoside, myricetin derivatives, caffeoylquinic acid derivatives, a luteolin/kaempferol-type glucoside, and a biflavone of the biapigenin/amentoflavone type. These findings suggest that HoE possesses dual antidepressant-like and antinociceptive properties and support its further evaluation for disorders at the affect–pain interface.

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  • MakaleYalnız künye2026
    Experimental investigation on hybrid parabolic trough collector and thermoelectric generator system for energy, economic, and environmental aspects

    Cuce, Pinar Mert; Guclu, Tamer; Cuce, Erdem; Bouabidi, Abdallah; El Hadi Attia, Mohammed

    This study experimentally investigates the thermal and electrical performance, economic feasibility, and environmental impacts of a hybrid energy system integrated with a parabolic trough collector (PTC) and thermoelectric generator (TEG). In the established system, solar energy is converted into electrical and thermal energy using a steam turbine and TEG. Experimental data indicate that the system operates with an average efficiency of 71.44%, which varies depending on the intensity of solar radiation. The overall energy efficiency of the system is calculated as 14.51%. In the economic analysis, the payback period of the designed system is approximately 5.4 years, while the levelised cost of energy production (LCOE) is calculated to be 0.075 USD kWh−1. The environmental assessment indicates that the system can prevent 356.18 kg of CO2 emissions annually and save approximately 1499.72 L of water. These findings demonstrate that hybrid systems offer an economically and environmentally sustainable and efficient alternative to energy production.

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  • MakaleYalnız künye2026
    Global boundedness to a chemotaxis system with modified nonlocal and nonlinear reaction

    Akkoyunlu, Ebubekir

    This paper deals with the following Neumann initial-boundary value problem (Formula presented.) where (Formula presented.) (Formula presented.) is a bounded domain with smooth boundary, (Formula presented.), (Formula presented.), (Formula presented.), (Formula presented.), and (Formula presented.). The initial data satisfy (Formula presented.) where (Formula presented.), (Formula presented.), and (Formula presented.)  on (Formula presented.). We rigorously prove that the problem admits a unique global classical solution which is uniformly bounded in time if one of the following conditions holds: (Formula presented.) or (Formula presented.).

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  • MakaleYalnız künye2026
    Hot injection synthesis of metal-doped Ag2S nanocrystals: A novel multifunctional approach for cancer therapy, antibacterial strategies, and antioxidant defense

    ULUSU, Funda; OZEL, Sultan Suleyman; Sarilmaz, Adem; ULUSU, Yakup

    This pioneering study presents the synthesis and comprehensive evaluation of bare and metal-doped Ag₂S nanocrystals (NCs) as multifunctional agents with potential applications in antibacterial, antioxidant, and anticancer therapies. The incorporation of manganese, nickel, cobalt, and zinc into Ag₂S NCs resulted in a notable enhancement of their bioactivity, representing a novel approach in nanomaterial design. The antibacterial assessments revealed that Mn:Ag₂S NCs were the most potent candidate, exhibiting exceptional activity against S. aureus and E. coli, with the lowest MIC values recorded at 1.28 mg/mL and 1.08 mg/mL, respectively. The antioxidant studies demonstrated that the Mn:Ag₂S NCs exhibited remarkable free radical scavenging and ferric reducing capacities, with the lowest IC50 values (22.69 µg/mL for DPPH and 61.31 µg/mL for FRAP) underscoring their potential to mitigate oxidative stress. Importantly, cytotoxicity assays revealed that Ni:Ag₂S and Mn:Ag₂S nanocrystals selectively inhibited the proliferation of human colon cancer cells (HT-29), achieving IC50 values of 61.51 µg/mL and 90.12 µg/mL, respectively. Furthermore, these NCs demonstrate reduced toxicity towards mouse fibroblast cells (L929). This selective cytotoxicity indicates the potential of these agents in targeted cancer therapies, thereby reducing damage to healthy tissues. To the best of our knowledge, this is the first study to systematically explore the synergistic effects of metal doping on the multifunctional properties of Ag₂S NCs. These findings provide a robust basis for further in vivo studies and offer new avenues for the development of safe and effective nanomaterials in biomedical applications, particularly as antimicrobial, antioxidant, and anticancer agents.

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  • MakaleYayıncıda açık erişim2026
    Analysis of the Impact of Blue Stain on the Color, Glossiness, and Whiteness Properties of Scots Pine Lumber

    Ayata, Ümit; Peker, Hüseyin; Ulay, Göksel; Çamlıbel, Osman; Atilgan, Abdi

    It is known that blue stain causes a loss of price value for Scots pine wood in the wood trade due to the visual defects it creates. In this study, color parameters [red color tone (a*), lightness (L*) value, yellow (b*) color tone, tone angle (h°) value, and chroma (C*) value], whiteness index (WI*) values, and glossiness measurements [at angles of 20°, 60°, and 85°] were compared in Scots pine (Pinus sylvestris L.) wood with normal and blue rot conditions. According to the color parameters obtained, it was determined that the L* value decreased by 11.43%, a* by 79.95%, b* by 28.86%, and C* by 32.75%, while the h° value increased by 17.74%. With the blue coloration, decreases were observed in the 20° glossiness values measured in the ⃦ and ⊥ directions, while increases were observed in the 60° and 85° glossiness values measured in the ⃦ and ⊥ directions. With the blue coloration, decreases of 12.86% in the ⊥ direction and 29.87% in the ⃦ direction in the WI* values were observed. According to these results, it was determined that the wood material with the blue coloration disease had a darker color.

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