Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2026Scopus SJRQ2
    Bioactive profile and mineral composition of fruit extracts from four wild hawthorn (Crataegus spp.) species

    Çakır, Özlem; Çınar Topçu, Kübra; Sefali, Abdurrahman; Bayyiğit, İshak; İlhan, Gülçe; Singh, Jyoti

    This study compared the antioxidant capacity, total phenolic content (TPC), phenolic composition, lipid oxidation level, and mineral profiles of extracts obtained from four wild hawthorn species (Crataegus tanacetifolia, C. orientalis subsp. orientalis, C. orientalis subsp. szovitsii, and C. monogyna) collected from northeastern Türkiye. Significant interspecific variations were observed in DPPH, FRAP, and CUPRAC assays. While C. monogyna had the highest reducing capacity and TPC, C. orientalis subsp. szovitsii had the highest DPPH activity. Ultra-high performance liquid chromatography coupled to tandem mass spectrometry analysis showed that catechin, epicatechin, chlorogenic acid, and quinic acid were the major phenolics, and were particularly abundant in C. monogyna. Despite having a high phenolic content, C. monogyna had the highest malondialdehyde level, indicating that phenolics alone were insufficient to fully inhibit lipid oxidation. Inductively coupled plasma-mass spectrometry mineral analysis detected high levels of K, Mg, and P in all species. Principal component analysis effectively distinguished the species based on their antioxidant, phenolic, and mineral profiles. Overall, hawthorn fruits were confirmed as valuable sources of natural antioxidants and essential minerals.

    AtıfScopus1WoS1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleAçık Erişim2026Scopus SJRQ4
    Effect of Seismic Isolation on Earthquake Behavior of Mid-Rise Reinforced Concrete Building Systems

    Delikkaya, Uğur; Karabulut, Pembe Merve; Ergün, Mustafa

    When the latest updated Türkiye Earthquake Hazard Map and Active Fault Maps are examined, it is seen that a large part of Türkiye's surface area is at earthquake risk. With increasing urbanization, the majority of the population lives in cities built on active earthquake faults. The 7.8 and 7.5 magnitude earthquakes centered in Kahramanmaraş, Pazarcık, and Elbistan occurred in Türkiye on February 6, 2023, and caused significant loss of life and major damage in 10 provinces. In the damage assessment studies conducted after the earthquakes, it was determined that the damage in structures constructed with tunnel formwork systems was less than the damage in other structural systems. The importance of seismic isolators in such a severe earthquake was once again revealed. Within the scope of this study, the earthquake performance of mid-rise buildings constructed with tunnel formwork systems and mid-rise buildings constructed with reinforced concrete carcass construction systems was compared with and without isolators for different soil classes. When the obtained results were examined, it was observed that the earthquake performance of the structures constructed with the tunnel formwork system was better than that of the structures constructed with the reinforced concrete frame structure system and that in cases where a seismic isolator was used, the isolator positively affected the forces acting on the structure and the structure displacements.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    • SDG 11 · Sürdürülebilir Şehirler ve Topluluklar
  • MakaleAçık Erişim2026Scopus SJRQ4
    Experience-Based Decentralized Marketing and Advertising (Ex-Mad): A Blockchain Framework for Transparent and Fair Digital Campaigns

    Ayberkin, Doruk; Özen, Üstün

    The contemporary digital advertising ecosystem faces critical technical and operational challenges, primarily driven by centralized intermediaries, data opacity, and privacy vulnerabilities. To address these systemic issues, this paper proposes "Ex-Mad," a decentralized architecture leveraging blockchain technology and the Interplanetary File System (IPFS). The proposed framework integrates three core architectural layers: the user entities (advertisers and end-users), the blockchain ledger for immutable transaction recording, and IPFS for distributed content storage. Unlike traditional centralized models, Ex-Mad utilizes smart contracts to automate campaign management and enforce trustless interactions, ensuring verifiable reward distribution based on user contribution without third-party validation. Furthermore, the integration of IPFS optimizes on-chain storage costs by handling large media files off-chain while maintaining data integrity through cryptographic hashes. The system design enhances auditability through a tamper-proof ledger, eliminates single points of failure, and provides a technically robust alternative to current ad-tech intermediaries. This study demonstrates how the proposed architecture improves system efficiency, reliability, and cost-effectiveness in the digital advertising domain.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
  • MakaleYayıncıda açık erişim2023Scopus SJRQ4
    Development of Alkali-Activated Binders from Recycling Regional Tuff and Marble Wastes

    Tekin, İlker; Ciza, Baraka; Gökçe, H.S.

    The sustainability goals of the developing world have led many industries to recycle their wastes and reduce emitting greenhouse gases. To contribute to these environmental responsibilities, this study has focused on the development of eco-friendly binder materials from regional ground tuff and marble wastes by the activation of sodium silicate (Na2SiO3) and sodium hydroxide (NaOH) or slaked lime (Ca(OH)2). The results of this study show that alkali-activated composites experienced expansion, drying shrinkage cracking, leaching, and efflorescence. The compressive strength values of the NaOH and Ca(OH)2-activated pastes reached up to 15 MPa and 9 MPa, respectively. A reduction in NaOH molarity improved the compressive strength, dimensional stability, and durability of tuff-based alkali-activated pastes.

    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus5OpenAlex3
    Scopusİncele
  • MakaleAçık Erişim2022Scopus SJRQ2
    Existence and multiplicity of solutions for p(.)-Kirchhoff-type equations

    Ayazoğlu, Rabil; Akbulut, Sezgin; Akkoyunlu, Ebubekir

    This paper is concerned with the existence and multiplicity of solutions of a Dirichlet problem for p(.) - Kirchhoff-type equation (Formula Presented). Using the mountain pass theorem, fountain theorem, dual fountain theorem and the theory of the variable exponent Sobolev spaces, under appropriate assumptions on f and M, we obtain results on existence and multiplicity of solutions

    AtıfScopus9WoS9OpenAlex9
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2022Scopus SJRQ3
    Investigation of biological activities of plant extract and green synthesis silver nanoparticles obtained from Gilaburu (Viburnum opulus L.) fruits

    Şahin, Birgütay; Bülbül, Ali Savaş; Çelik, I. Seyfettin; Korkmaz, Nesrin; Karadağ, Ahmet

    In this study, biological activities of silver nanoparticles (AgNP) synthesized by green synthesis method using the fruit extract of Gilaburu (Viburnum opulus L.) plant were investigated. The characterization of the synthesized AgNPs was performed by ultraviolet visible region spectroscopy (UV-Vis), Fourier transform - infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and X-ray diffraction (XRD) techniques. The crystal size was found to be 52.32 nm when the XRD data were calculated with the Debye-Scherrer's equation. The antimicrobial activities of extract and AgNPs were investigated by microdilution and disk diffusion methods. Antibiofilm activities were examined by the crystal violet technique. The cytotoxic effects of the extract and AgNPs against MCF-7 (human breast cancer) and HUVEC (human umbilical vein endothelial cells) cell lines were evaluated by MTT assay. The IC50 values for the HUVEC line were found to be 0.97 mg/mL (AgNP) and 85.24 mg/mL (extract), while the IC50 values for the MCF-7 line were determined as 0.022 µg/mL (AgNP) and 0.021 µg/mL (extract). To our knowledge, this is the first report to comprehensively examine the biological activities of V. opulus L. extract and biosynthetic AgNPs.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus11WoS11OpenAlex10TR Dizin1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleAçık Erişim2021Scopus SJRQ4
    The effect of pH on removal of phosphate from water using aluminum electrodes by electrocoagulation method; [Alüminyum elektrotlar kullanılarak elektrokoagülasyon yöntemi ile sulardan fosfat gideriminde pH'ın etkisi]

    İrdemez, Şahset; Bingül, Züleyha; Kul, Sinan; Ekmekyapar Torun, Fatma; Demircioğlu, Nuhi

    In this study, the effect of wastewater pH on phosphate removal by electrocoagulation method using aluminum plate electrodes was investigated. For this purpose, experiments were carried out at initial pH values ranging from 3-10, and the effect of the initial pH of the wastewater on phosphate removal efficiency, energy consumption and reaction rate was analyzed. From the results obtained, it was determined that the initial pHs of the optimum wastewater was 3 and 4. Because at low pH, both phosphate removal efficiency is high and the energy consumption of the system is low. While 97% removal efficiency is reached in 20 minutes at pHi=3, it increases in this period with the increase of the wastewater initial pH. These data show that the removal rate is higher at lower initial pHs. While the 1st degree reaction rate constant at pHi=3 is k1=0.2154 min-1, this value decreases to k1=0.071 min-1 at pHi=10. At pHi=3, the energy consumption of the system has been determined as 0.553 kWh m-3 in 12 minutes of contact time. In addition, in the measurements made during the trials, it was observed that the highest PO4-P removal occurred during the period when the pH of the system was between 5-7.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus4OpenAlex1
    ScopusTR Dizinİncele
  • MakaleAçık Erişim2021Scopus SJRQ2
    Targeting cov-2 spike rbd and ace-2 interaction with flavonoids of anatolian propolis by in silico and in vitro studies in terms of possible covid-19 therapeutics

    Güler, Halil İbrahim; Ay Şal, Fulya; Can, Zehra; Kara, Yakup; Yildiz, Oktay; Beldüz, Ali Osman; Çanakçi, Sabriye; Kolayli, Sevgi

    Propolis is a multi-functional bee product rich in polyphenols. In this study, the inhibitory effect of Anatolian propolis against SARS-coronavirus-2 (SARS-CoV-2) was investigated in vitro and in silico. Raw and commercial propolis samples were used, and both samples were found to be rich in caffeic acid, p-coumaric acid, ferulic acid, t-cinnamic acid, hesperetin, chrysin, pinocembrin, and caffeic acid phenethyl ester (CAPE) at HPLC-UV analysis. Ethanolic propolis extracts (EPE) were used in the ELISA screening test against the spike S1 protein (SARS-CoV-2): ACE-2 interaction for in vitro study. The binding energy values of these polyphenols to the SARS-CoV-2 spike and ACE-2 protein were calculated separately with a molecular docking study using the AutoDock 4.2.6 program. In addition, the pharmacokinetics and drug-likeness properties of these eight polyphenols were calculated according to the SwissADME tool. The binding energy value of pinocembrin was highest in both receptors, followed by chrysin, CAPE, and hesperetin. Based on the in silico modeling and ADME (absorption, distribution, metabolism, and excretion) behaviors of the eight polyphenols, the compounds exhibited the potential ability to act effectively as novel drugs. The findings of both studies showed that propolis has a high inhibitory potential against the Covid-19 virus. However, further studies are now needed.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus35WoS29OpenAlex39
    ScopusWeb of SciencePubMedTR Dizinİncele
  • MakaleAçık Erişim2019Scopus SJRQ3
    Biodiversity and characterization of gram-positive, catalase-positive cocci isolated from pastırma produced under different curing processes

    Fettahoğlu, Kübra; Çinar, Kübra; Kaya, Mükerrem; Kaban, Güzin

    The aim of this study was to determine the effects of different curing temperatures (4 °C or 10 °C) and agents (KNO3 or NaNO2) on microbiological and physicochemical properties of pastırma and diversity of gram-positive, catalase-positive cocci (GCC+) and also to investigate some technological properties of the strains. Four different groups of pastırma were produced applying different curing temperatures and agents. After production, GCC+ isolated from pastırma were subjected to phenotypic and genotypic (16S rRNA sequencing) identification. Genotypically characterized strains were evaluated for their technological properties. In all groups, aw and pH were observed to be under 0.90 and over 5.5, respectively. In genotypic identification, 45 isolates were identified as Staphylococcus vitulinus, while other isolates identified were S. equorum (n = 15), S. saprophyticus (n = 15), and S. xylosus (n = 12). All of the strains could grow at different salt concentrations (8% and 15%) and temperatures (4 °C, 10 °C, and 37 °C). Four strains of S. saprophyticus showed strong lipolytic activity while nine strains of S. vitulinus had strong proteolytic activity. This study showed that different curing temperatures and agents are particularly effective on the microflora in pastırma; however, these factors do not cause a high diversity in GCC+ in terms of species.

    • SDG 2 · Açlığa Son
    AtıfScopus6WoS6OpenAlex7TR Dizin2
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleAçık Erişim2019Scopus SJRQ3
    Plasma polymerized linalool (ppLin): An antimicrobial and biocompatible coating

    Çakmak, Kenan; Bayram, Özkan; Solak, Kübra; Kaban, Güzin; Şimşek, Önder; Mavi, Ahmet

    Bacterial infections in medical devices and drug resistance of bacteria can cause chaos in the world due to loss of lives in addition to the cost of device revisions, quarantine, disinfection of infected areas, and patient treatment. Antibacterial coatings of essential oils on medical devices can prevent bacterial attachment and reduce costs. Linalool is an antibacterial constituent of essential oils. Herein, we examine for the first time the fabrication and characterization of radio frequency (RF) plasma polymerized hydrophilic thin films from linalool (ppLin) by varying deposition parameters (RF power and deposition time) and the behavior of ppLin with two bacteria (Escherichia coli and Staphylococcus aureus) commonly related to microbial contamination of medical devices. While a dramatic reduction in E. coli and S. aureus attachment was observed on ppLin films, their hydrophilic surface was also bactericidal to S. aureus. Additionally, ppLin films were shown to be adherent and noncytotoxic to human fibroblast cells. ppLin can be potentially integrated into medical and other clinical devices as a promising low-cost biocompatible antimicrobial coating.

    AtıfScopus8WoS8
    ScopusWeb of ScienceTR Dizinİncele
  • Dergi
    Turkish Journal of Veterinary and Animal Sciences
  • Dergi
    Turkish Journal of Mathematics
  • Dergi
    Turkish Journal of Agriculture and Forestry
  • Dergi
    Turkish Journal of Biology
  • Dergi
    Turkish Journal of Chemistry
  • Dergi
    El-Cezeri Journal of Science and Engineering