Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Ceylan, Halil Ibrahim(4)
- Akman, Onur(3)
- Bulgay, Celal(3)
- Ceylan, Nagihan Burcak(3)
- Ahmetov, Ildus I.(2)
- Badicu, Georgian(2)
- Bayraktar, Isik(2)
- Bayram, Sinan(2)
- Dergaa, Ismail(2)
- Dertli, Enes(2)
- Ergun, Mehmet Ali(2)
- Generozov, Edward V.(2)
- Jamoussi, Henda(2)
- Kazan, Hasan Hueseyin(2)
- Kulemin, Nikolay A.(2)
- Kurek-Górecka, Anna(2)
- Larin, Andrey K.(2)
- Mijaica, Raluca(2)
- Semenova, Ekaterina A.(2)
- Stefanica, Valentina(2)
- Ulucan, Korkut(2)
- Yıldırım, Ümit(2)
- Zorba, Erdal(2)
- Özçelik, Beraat(2)
- Adams, Gary G.(1)
- Akmese Tarlan, Yasemin(1)
- Akpinar, Erol(1)
- Aksu, Emrah Hicazi(1)
- Alkay, Zuhal(1)
- Almutairi, Fahad(1)
- Arioglu-Tuncil, Seda(1)
- Arslaner, Ayla(1)
- Balint, Lorand(1)
- Balwierz, Radoslaw(1)
- Bayaman, Rabia Yusra(1)
- Bayar, Serkan(1)
- Bayram, And Sinan(1)
- Bayram, Nesrin Ecem(1)
- Ben Nsir, Siwar(1)
- Ben Othman, Rym(1)
Yayınlar
- MakaleAçık Erişim2022Scopus SJRQ1Recovery of Polyphenols Using Pressurized Hot Water Extraction (PHWE) from Black Rosehip Followed by Encapsulation for Increased Bioaccessibility and Antioxidant Activity
Kasapoğlu, Kadriye Nur; Demircan, Evren; Gültekin-Özgüven, Mine; Kruger, Johanita; Frank, Jan; Arslaner, Ayla; Özçelik, Beraat
In this work, pressurized hot water extraction (PHWE) of hydrophilic polyphenols from black rosehip fruit was maximized using response surface methodology for simultaneous optimization in terms of extraction yield, total antioxidant capacity, total (poly)phenols, catechin, total monomeric anthocyanins, and cyanidin-3-O-glucoside. Extraction parameters, including temperature (X1: 40–80 °C) and the solvent-to-solid ratio (X2: 10–40 mL/g), were investigated as independent variables. Experimentally obtained values were fitted to a second-order polynomial model, and optimal conditions were determined using multiple regression analysis and analysis of variance. The black rosehip extract (BRE) obtained at optimized PHWE conditions was further encapsulated in biopolymer-coated liposomes and spray dried to enhance its processing and digestive stability. After reconstitution, the fabricated particles had an average size of 247–380 nm and a zeta-potential of 15–45 mV. Moreover, encapsulation provided remarkable protection of the phenolics under in vitro gastrointestinal digestion conditions, resulting in up to a 5.6-fold more phenolics in the bioaccessible fraction, which also had 2.9–8.6-fold higher antioxidant activity compared to the nonencapsulated BRE. In conclusion, PHWE in combination with a biopolymer coating is a potent method for the production of stable and safe edible natural extracts for the delivery of (poly)phenolic compounds in food and dietary supplements.
AtıfScopus20WoS19OpenAlex20
İncele - MakaleAçık Erişim2021Scopus SJRQ1Antioxidant, antimicrobial activities and fatty acid compositions of wild berberis spp. by different techniques combined with chemometrics (PCA and HCA)
Gıdık, Betül
Interest in medicinal plants and fruits has increased in recent years due to people beginning to consume natural foods. This study aims to investigate the total phenolic flavonoid content, antiox-idant activity, condensed tannin content, oil content, and fatty acid compositions of five local breeds of Berberis spp. from Bayburt, Turkey, and their antioxidant and antimicrobial activities. The fatty acid composition of samples was performed with gas chromatography-mass spectrometry (GC-MS), and the total fatty acid content of samples was between 6.12% and 8.60%. The main fatty acids in Berberis spp. samples were α-linolenic acid (32.85–37.88%) and linoleic acid (30.98–34.28%) followed by oleic acid (12.85–19.56%). Two antioxidant assays produced similar results, demonstrating that extracts of wild B. vulgaris L. had the highest ferric reducing antioxidant power (FRAP) (621.02 µmol FeSO4.7H2O/g) and 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) (0.10 SC50 mg/mL) values. According to principal component analysis (PCA), four components were determined. In addition, two main groups were determined according to hierarchical cluster analysis (HCA), and wild and culture of B. vulgaris L. were in different subgroups. This is the first original report about the fatty acid composition and oil content of Berberis spp. grown in Bayburt, Turkey. The obtained results indicate that B. integerrima Bunge and B. vulgaris, which have especially remarkable fatty acid content, antioxidant, and antimicrobial activity, could be potential sources for these properties in different areas of use.
AtıfScopus45WoS41OpenAlex48İncele - Derleme MakaleAçık Erişim2020Scopus SJRQ2Avocado-Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited
Salehi, Bahare; Rescigno, Antonio; Dettori, Tinuccia; Calina, Daniela; Docea, Anca Oana; Singh, Laxman; Cebeci, Fatma; Özçelik, Beraat; Bhia, Mohammed; Dowlati Beirami, Amirreza
Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts made from fruits and seeds of avocado and soybean oil. Characterized by its potent anti-inflammatory effects, this ASU mixture is recommended to act as an adjuvant treatment for osteoarthritic pain and slow-acting symptomatic treatment of hip and knee osteoarthritis; autoimmune diseases; diffuse scleroderma and scleroderma-like states (e.g., morphea, sclerodactyly, scleroderma in bands). Besides, it was reported that it can improve the mood and quality of life of postmenopausal women in reducing menopause-related symptoms. This article aims to summarize the studies on biological effects of the avocado-soybean unsaponifiable, its chemical composition, pharmacotherapy as well as applications in autoimmune, osteoarticular and menopausal disorders. Finally, we will also discuss on its safety, toxicological and regulatory practices.
AtıfScopus98WoS80OpenAlex103İncele - MakaleAçık Erişim2020Scopus SJRQ1Isolation and Biophysical Characterisation of Bioactive Polysaccharides from Cucurbita Moschata (Butternut Squash)
Jiwani, Shahwar Imran; Gillis, Richard B.; Besong, David; Almutairi, Fahad; Erten, Tayyibe; Kök, M. Samil; Harding, Stephen E.; Paulsen, Berit S.; Adams, Gary G.
Cucurbits are plants that have been used frequently as functional foods. This study includes the extraction, isolation, and characterisation of the mesocarp polysaccharide ofCucurbita moschata. The polysaccharide component was purified by gel filtration into three fractions (NJBTF1, NJBTF2, and NJBTF3) of different molecular weights. Characterisation includes the hydrodynamic properties, identification of monosaccharide composition, and bioactivity. Sedimentation velocity also indicated the presence of small amounts of additional discrete higher molecular weight components even after fractionation. Sedimentation equilibrium revealed respective weight average molecular weights of 90, 31, and 19 kDa, with the higher fractions (NJBTF1 and NJBTF2) indicating a tendency to self-associate. Based on the limited amount of data (combinations of 3 sets of viscosity and sedimentation data corresponding to the 3 fractions), HYDFIT indicates an extended, semi-flexible coil conformation. Of all the fractions obtained, NJBTF1 showed the highest bioactivity. All fractions contained galacturonic acid and variable amounts of neutral sugars. To probe further, the extent of glycosidic linkages in NJBTF1 was estimated using gas chromatography-mass spectrometry (GCMS), yielding a high galacturonic acid content (for pectin polysaccharide) and the presence of fructans-the first evidence of fructans (levan) in the mesocarp. Our understanding of the size and structural flexibility together with the high bioactivity suggests that the polysaccharide obtained fromC. moschatahas the potential to be developed into a therapeutic agent.
AtıfScopus8WoS10OpenAlex10İncele - DergiWater (Switzerland)
- DergiISPRS International Journal of Geo-Information
- DergiSymmetry
- DergiMolecules
- DergiGENES
- DergiBIOMOLECULES
- DergiHEALTHCARE
- DergiMETABOLITES
- DergiTOXICS
- DergiFERMENTATION-BASEL
- DergiPOLYMERS
- DergiLIFE-BASEL
- DergiNUTRIENTS