Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Kutlu, Naciye(11)
- Şahin, Engin(6)
- Ecem Bayram, Nesrin(5)
- Sönmez Sari, Ebru(5)
- Can, Zehra(4)
- Gerçek, Yusuf Can(3)
- Gıdık, Betül(3)
- Kalay, Erbay(3)
- Kamiloğlu, Aybike(3)
- Kızıl, Hamit Emre(3)
- Saritas, Serdar(3)
- Semerci Çakmak, Vahide(3)
- Teber, Ahmet(3)
- Abca, Tuğba Elbir(2)
- Abdioglu, Murat(2)
- Aksoy, Dilara Arzugül(2)
- Apaydin, Emine(2)
- Arslaner, Ayla(2)
- Bayram, Nesrin Ecem(2)
- Bayram, Sinan(2)
- Baştürk, Fatma Nur(2)
- Birinci, Ahmet(2)
- Dertli, Enes(2)
- Gercek, Yusuf Can(2)
- Guner, Sait Baris(2)
- Gunes, Huseyin(2)
- Isci, Asli(2)
- Kahveci, Hakan(2)
- Kamiloglu, Aybike(2)
- Kara, Yakup(2)
- Koroglu Kaba, Nagihan(2)
- Ozdemir, Ahmet(2)
- Sakiyan, Ozge(2)
- Terzi, Handan(2)
- Tozlu, Alperen(2)
- Çelik, Saffet(2)
- Öztekin, Sebahat(2)
- Acar, Emre Ali(1)
- Adal, Samiye(1)
- Adiyaman, Gokhan(1)
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ1A qualitative study on Turkey's earthquakes, the century's catastrophe: Perspectives and coping methods of surviving nursing students
Sönmez Sari, Ebru; Terzi, Handan
Aim: To understand the experiences and coping strategies of nursing students who were impacted by Turkey's once-in-a-century catastrophic earthquakes in 2023. Background: Nursing students rarely experience a disaster in person, and their imagination can be limited. Methods: This study used a descriptive-qualitative study design. It was conducted with 17 first-year nursing students, studying at a university in the northeastern part of Turkey, who survived the earthquake. A personal information form and a semistructured questionnaire were used to collect the data. The data were collected between March and April 2023 and analyzed using the content analysis method and the MaXQDA programme. Results: The data were grouped into three main themes—“What ‘earthquake’ was and what it is now?,” “Am I aware of the ‘earthquake’ now?,” and “Coping mechanisms and supporting systems”—and categorized into seven subthemes. Conclusions: The experiences of earthquake-affected nursing students emphasized the importance of being prepared for disasters and meeting their emotional needs. Implications for nursing practice and policies: Including specific courses and case studies regarding disasters, whether natural or human-made, in education programs can ensure better prepared nurses. Also, the integration of content about management and coping with such crises into nursing curricula is considered vital.
AtıfScopus5WoS4OpenAlex7
İncele - Derleme MakaleAçık Erişim2025Scopus SJRQ1Thawing frozen foods: A comparative review of traditional and innovative methods
Çalışkan Koç, Gülşah; Özkan Karabacak, Azime; Süfer, Özge; Adal, Samiye; Çelebi, Yasemin; Delikanlı Kıyak, Berrak; Öztekin, Sebahat
Due to the changing consumer lifestyles, the tendency to adopt foods that require less preparation time and offer both variety and convenience has played a significant role in the development of the frozen food industry. Freezing is one of the fundamental food preservation techniques, as it maintains high product quality. Freezing reduces chemical and enzymatic reactions, lowers water activity, and prevents microbial growth, thereby extending the shelf life of foods. The freezing and thawing procedures directly impact the quality of frozen foods. The degree of tissue damage is determined by the freezing rate and the structure of the ice crystals that form during the freezing process. Generally, thawing occurs more slowly than freezing. During thawing, microorganisms, as well as chemical and physical changes, can cause nutrient damage. Thus, the goal of this review is to identify innovative and optimal thawing strategies. In order to save energy and/or improve quality, new chemical and physical thawing aids are being developed alongside emerging techniques such as microwave-assisted, ohmic-assisted, high pressure, acoustic thawing, and so on. In addition to discussing the possible uses of these technologies for the thawing process and their effects on food quality, the purpose of this study is to present a thorough comparative overview of recent advancements in thawing techniques.
AtıfScopus58WoS50OpenAlex52İncele - MakaleAçık Erişim2025Scopus SJRQ1Effects of Augmented Reality and Video-Based Learning in Inquiry-Based Science Education on Academic Achievement and Motivation to Learn Science
Arici, Faruk; Yilmaz, Rabia Meryem
Background: Inquiry-based learning (IbL) has significantly contributed to science education, and this impact can be enhanced with technology. Augmented Reality (AR) offers 3D visualisation and interactive experiences, whereas Video-based Learning (VbL) provides narratives with visual and audio support. Both methods aid students in exploring, understanding and boosting their motivation to learn science (MtLS). Objectives: This study examines the effect of AR and VbL within an IbL environment on students' MtLS and academic achievement. Methods: A mixed-method research design was used, with a quasi-experimental approach for the quantitative aspect and a multiple case study for the qualitative part. Participants included two experimental groups and a control group. Experiment 1 (25 participants) received AR and IbL, Experiment 2 (26 participants) received VbL and IbL and the control group (25 participants) received only IbL instruction. Data were collected using academic achievement tests, MtLS scales and semi-structured interviews. Quantitative data were analysed via ANCOVA using SPSS, whereas qualitative data underwent content analysis. Results and Conclusions: Results indicated that AR technology in the IbL environment was more effective than VbL in enhancing academic achievement and MtLS. The VbL group also performed better than the IbL-only group. With regard to the MtLS subfactors, no significant differences were observed between the groups in terms of motivation for participation. However, Experiment-1 demonstrated significant improvement in motivation for conducting research and motivation for collaboration, compared to Experiment-2 and the control group. Experiment 2 showed significant results compared to the control group. Experiment-1 demonstrated significant improvement in motivation for performance and motivation for communication compared to the control group. Although Experiment-1 yielded higher results than Experiment-2, this difference was not significant. Experiment 2 and the control group demonstrate notable parallels. The findings of this study indicate that AR effectively supports academic achievement and MtLS in an IbL environment. Consequently, the utilisation of AR is advocated for middle school students engaged in the study of vertebrates.
AtıfScopus2WoS2OpenAlex5İncele - MakaleAçık Erişim2025Scopus SJRQ2High-Performance Microwave-Absorbing Hemp Textile: Ni-Zn Ferrite and Multiwalled Carbon Nanotubes-Infused Nanocomposite for X-Band Electromagnetic Interference Shielding
Teber, Pembe; Teber, Ahmet; Karakaş, İbrahim Hakkı
This study aims to develop a flexible and sustainable electromagnetic (EM) wave-absorbing material by using hemp fabric as a substrate incorporated with multiwalled carbon nanotubes (MWCNTs) and magnetic Ni-Zn ferrite nanoparticles (NPs). In this context, the objective is to achieve effective EM attenuation across a wide frequency range using a green, lightweight composite to meet the rising demand for ecofriendly shielding in electronic and communication systems. Ni0.5Zn0.5Fe2O4 and MWCNT composite NPs are uniformly dispersed in a molten paraffin binder and impregnated into hemp fabrics. The magnetic NPs are synthesized via the microwave-assisted combustion method. The EM parameters of the resulting structure are determined in the X-band using experimental scattering data and the Nicholson–Ross–Weir method. Absorption performance is evaluated based on varying weight ratios of magnetic NPs and MWCNTs, with an emphasis on impedance matching. The results indicate that combining dielectric and magnetic components significantly enhances absorption. A maximum reflection loss of −72.42 dB and a 3.81 GHz bandwidth (covering over 90.71% of the X-band) are achieved at 10.08 GHz. Increasing Ni-Zn content shifts the resonance to higher frequencies. This sustainable, flexible composite shows strong potential for electromagnetic interference shielding, particularly in defense applications requiring radar invisibility.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2025Scopus SJRQ1Regulate Yourself, Improve Your Writing: The Hidden Power of Metacognitive Awareness and Self-Efficacy
Sarikaya, İsmail; Sökmen, Yavuz
This study aims to determine the serial mediatory effect of metacognitive writing awareness and writing self-efficacy in the relationship between primary school students' self-regulation and writing success. The study participants were 408 fourth-grade students attending public primary schools in two cities in eastern Turkey. This study is a correlational survey research. We used SPSS and PROCESS macros to analyze the data. The study revealed strong positive relationships between writing success and self-regulation, metacognitive writing awareness, and writing self-efficacy. It showed that the serial mediation role of metacognitive writing awareness and writing self-efficacy was significant. As one of the first studies to address these relationships, the study fills the gaps in the literature on writing success and sheds light on interventions to improve writing skills at the primary school level.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ1Design, Simulation, and Fabrication of High-Performance Metamaterial Absorber for EMI Mitigation and THz NDT/Imaging Applications: A Shape-Preserved GHz-to-THz Transition Approach
Teber, Ahmet
A metamaterial absorber (MMA) designed for the 5G FR2/mmWave bands (24.25–24.45 and 24.75–25.25 GHz) is simulated with CST Studio Suite and fabricated using laser and wet etching techniques. Absorption measurements are performed using horn antennas in conjunction with a vector network analyzer (VNA). The absorber achieves >95.8% absorption under normal incidence for Mode-1, while it exceeds 90% for Mode-2 in the 24.75–25.20 GHz. The simulation results are validated through an electrical equivalent circuit model and experimental data. This absorber presents a promising solution for electromagnetic interference (EMI) reduction and shielding applications. The same structure, scaled from mm to µm without shape alteration, achieved over 90% absorption in the terahertz (THz) region (24–26 THz), particularly in the 24–25.12 THz range. The THz region, known as the “THz gap”, presents challenges due to limited THz sources and detectors. However, technologies such as THz non-destructive testing (NDT) offer potential in biomedical, communication, and defense applications. From this perspective, the high performance and scalability to µm dimensions without changing the shape of the absorber make it suitable for high-frequency EM shielding applications. This dual behavior in the GHz and THz regions offers a versatile advantage due to its varied functionality.
AtıfScopus4WoS4OpenAlex3İncele - MakaleAçık Erişim2025Scopus SJRQ1Dietary Carvacrol Attenuates Cyclophosphamide-Induced Neurotoxicity: Implications for Food-Derived Neuroprotection and Molecular Mechanisms
Kızıl, Hamit Emre
Carvacrol (CRV) is a phenolic monoterpene abundant in culinary herbs such as oregano and thyme and is well known for its potent antioxidant, anti-inflammatory, and neuroprotective properties. This study investigated the ability of CRV to counteract neurotoxicity induced by cyclophosphamide (CP), a widely used antineoplastic agent. Male Wistar albino rats were divided into five groups and received CP and/or CRV treatments. Neurotoxicity and neuroprotection were evaluated through biochemical assays, real-time PCR, histopathological and immunohistochemical analyses, and behavioral testing (Morris Water Maze). CP administration led to significant increases in oxidative stress markers, disruption of antioxidant enzyme activities, upregulation of inflammatory mediators (NF-κB, TNF-α, iNOS), dysregulation of apoptotic regulators (increased Bax and Casp-3, decreased Bcl-2), alterations in autophagy markers (Beclin-1, LC3A, LC3B), and suppression of Notch1/Hes1 signaling. Histopathological analyses revealed neuronal degeneration, vascular hyperemia, and increased GFAP and 8-OHdG expression in brain tissue. CRV treatment, particularly at higher doses, effectively mitigated these biochemical, molecular, and histological alterations. Notably, CRV administration preserved spatial learning and memory function in CP-treated rats, as demonstrated by the Morris Water Maze test, indicating functional neuroprotection. These findings highlight the multifaceted neuroprotective mechanisms of CRV and suggest its potential as a food-derived bioactive compound for development into functional foods or dietary supplements to improve the quality of life for cancer patients undergoing chemotherapy.
AtıfScopus10WoS9OpenAlex11İncele - MakaleAçık Erişim2025Scopus SJRQ2Extraction of Phenolic Compounds From Lavender (Lavandula angustifolia L.) Plant by Natural Deep Eutectic Solvent and Greenness Assessment of Analytical Method With Modified Green Analytical Procedure Index
Ecem Bayram, Nesrin; Yenigün, Baran; Gerçek, Yusuf Can
In recent years, it has been important in terms of green technology and sustainability to promote the use of natural deep eutectic solvents (NADESs), especially those based on natural products, for the extraction of bioactive components with different functional properties from foods. Therefore, in this study, the effects of green extraction technology (ultrasonic-assisted extraction) and green solvents (NADESs) on the recovery of bioactive components from lavender (Lavandula angustifolia L.) were investigated and evaluated. In addition, the degree of greenness of the analytical method used during the study was determined using the modified green analytical procedure index (MoGAPI). In this context, the total phenolic content (TPC), total antioxidant capacity, and individual polyphenolic profiles of lavender extracts prepared with two different NADES were investigated by liquid chromatography-tandem mass spectrophotometer. Based on the results obtained, it was determined that NADES formed with choline chloride:formic acid (ChCl:FA) had a higher potential to extract bioactive components from lavender than NADES formed with ChCl:ethylene glycol (ChCl:EG). The TPC, antioxidant capacity, and total individual polyphenolic compound content of lavender extracted with these NADES were determined as 9.76 mg gallic acid equivalent/g, 20.83–104.39 mg Trolox equivalent/g, and 200.835 mg/kg, respectively. However, the degree of greenness determined by the MoGAPI tool of the analytical method used in this study was 78% and classified as ‘excellent green’. As a result, it can be concluded that NADES formed with ChCl:FA can be an alternative to conventional solvents for the extraction of bioactive components from lavender, as it provides a remarkable recovery of bioactive substances.
AtıfScopus5WoS4OpenAlex3İncele - MakaleAçık Erişim2025Scopus SJRQ2A Promising Antibacterial Inhibition of Propolis Extracts Against Carbapenem-Resistant Bacteria Isolated From Clinical Samples
Esertaş, Ülkü Zeynep; Inal, Neşe; Can, Zehra; Kolaylı, Sevgi
The increasing inadequacy of antibiotics against multidrug-resistant pathogens is a growing concern. In this study, the antibacterial activity of propolis extracts with different phenolic profiles against carbapenem-resistant clinical isolates was investigated. The antimicrobial activity of propolis extract was tested against Acinetobacter baumannii (K17, K16, and K21), Klebsiella pneumoniae (K22, and K19), and Stenotrophomonas maltophilia (E5, E7, and E4) bacterial strains isolated from tracheal aspirate and blood cultures. The total phenolic content and phenolic composition of the extracts were analyzed. Antimicrobial activity values examined according to the disk diffusion method were measured as minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The results showed that all propolis extracts showed different inhibition values against bacterial strains. As a result, the high inhibitory potential of the propolis extracts against resistant bacteria such as A. baumannii, K. pneumoniae, and S. maltophilia is promising for combating infections. However, the study needs to be supported by further randomized clinical studies.
AtıfScopus2WoS2OpenAlex4İncele - Derleme MakaleAçık Erişim2025Scopus SJRQ1Factors affecting the sustainability of open educational resource initiatives in higher education: A systematic review
Aksoy, Dilara Arzugül; Kurşun, Engin; Zawacki-Richter, Olaf
This systematic review aims to examine the factors that impact the sustainability of open educational resources (OER) initiatives. A total of 226 articles from the Web of Science, ERIC and SCOPUS databases were subjected to content analysis to identify factors that influence the sustainability of OER initiatives based on the 3M (macro, meso and micro) framework. Our findings reveal that OER sustainability is influenced by different factors in different contexts, such as platform, content creator, learner, learning material and institutional setting. Within the institutional context, institutional policies categorised as a macro and meso factor, were identified as the most frequently mentioned factor affecting OER sustainability. The factors of providing institutional support and incentives were identified as meso factors. For faculty and learners, meso and micro factors such as attitude, motivation, awareness of OER, time, ICT needs and digital literacy were frequently mentioned. Access emerged as a prominent meso factor within the OER platforms dimension. Quality was identified as a critical macro and meso factor for the sustainability of OER. After the quality factor, material-related factors such as licensing, interactivity and free access emerged. Finally, an OER sustainability framework is proposed along with recommendations for researchers, practitioners and administrators to promote sustainable OER practices.
AtıfScopus4WoS4OpenAlex9İncele - MakaleAçık Erişim2024Scopus SJRQ3Antioxidant Activities of Different Peanut (Arachis hypogaea L.) Market Types by Spectrophotometric Techniques Combined with Chemometrics
Gıdık, Betül; Can, Zehra; Önemli, Fadul
Peanut is rich in oil and protein and has a large content of bioactive constituents consisting of tocopherols, phytosterols, and so on. Generally, Virginia, Spanish, Valencia and Runner market types are grown of peanut. In this study, it is aimed to determine the antioxidant activity, total phenolic content and total flavonoid content of peanuts from four different market types, for the first time, and group them with principal component analysis (PCA) and hierarchical cluster analysis (HCA). For PCA, PC1 and PC2 explained 87.655 % of the total variation and, according to the HCA of peanut samples, two main groups were determined. The total phenolic content changed 1.556 to 2.899 mg GAE/g. The lowest value have seen at Spanish merket type to determine the antioxidant activities of peanut samples were maked FRAP and DPPH assay, the lowest FRAP value (8.136 μmol FeSO47H2O/g sample) was seen at Valencia market type, the highest (14.004 μmol FeSO47H2O/g sample) was seen at Virginia market type. It was determined that the total flavonoid, total phenolic content, and antioxidant activities of the Virginia, Valencia, Spanish, and Runner market types included in the study were different from each other, and the Virginia market type showed superior characteristics compared to the others. The results obtained suggest that Virginia market type may be preferred more especially in peanut cultivation for food uses. It is thought that this study can be a source for future studies by eliminating a deficiency in the literature.
AtıfScopus2WoS2OpenAlex2İncele - MakaleYalnız künye2024Scopus SJRQ2Effect of sesame protein/PVA nanofibers on oil separation and rheological properties in sesame paste
Yuzer, Mustafa Onur; Genccelep, Huseyin
This study aimed to prevent or minimize the oil phase separation that occurs during storage (0-90 days) of sesame paste at room temperature. In order to determine the changes during storage in the sesame paste samples, the zeta potential, rheological properties, and the separated oil ratio were determined. Significant (p < 0.01) effects of applied storage time and additives on the amount of oil separated in sesame pastes were determined. The oil separated in sesame paste samples varied between 3.83% and 16.29%. While the rate of separated oil increased three times in the control group over time, it showed an insignificant (p > 0.05) increase especially in the samples where 2% nanofiber was added. It was determined that the separation of the oil phase from the structure could be prevented up to 24.73% with the addition of SPI and up to 63.02% with addition of SPINL (nanofiber containing protein isolate) compared to the control. Practical applications: During storage, the particles in the sesame paste tend to precipitate, causing oil separation and residue cake, thus negatively affecting the acceptability of consumers. Additives were added in order to prevent or minimize oil phase separation, which occurs in sesame paste stored at room temperature and is not desired by consumers. As additives, nanofibers containing sesame proteins produced by the electrospinning method and sesame protein isolates (SPIs) were added. Added additives acted by preventing the separation of the oil phase from the structure. It has been determined that the addition of SPI to sesame pastes does not completely prevent the problem of oil separation in sesame paste, but is effective in delaying and reducing it. Since the oil decomposition can be reduced, the amount of oil separated and therefore the part that can sink to the bottom will decrease, so sesame paste will be consumed more appropriately and will contribute to the country's economy.
AtıfScopus9WoS7OpenAlex7İncele - MakaleAçık Erişim2024Scopus SJRQ1Ultrasound-assisted deep eutectic solvent extraction of bioactive compounds from persimmon calyx
Kutlu, Naciye; Kamiloğlu, Aybike; Abca, Tuğba Elbir; Yilmaz, Özlem
Abstract: This study aimed to investigate the ultrasound-assisted extraction of bioactive compounds from persimmon (Diospyros kaki) calyx by deep eutectic solvents (DES) with different molar ratios. For this reason, the prepared DES extracts’ total phenolic–flavonoid compounds and antioxidant activities (1,1-diphenyl-2-picrilhydrazyl radical scavenging activity [DPPH•], Cupric Reducing Antioxidant Capacity (CUPRAC), and ferric reducing antioxidant power [FRAP]) were investigated as a result of the experimental design and optimization study conducted for this purpose. A sonication time of 20 min was determined as the optimal condition. Under these conditions, a molar ratio of 1.9:1 (lactic acid:choline chloride) and a water ratio of 70% provided the highest phenolic/flavonoid compounds and antioxidative activity. Correlations among water ratio, molar ratio, and sonication time were determined using principal component analysis (PCA). In conditions where total flavonoid compound, FRAP, and DPPH• are high due to PCA, it can be concluded that the sonication time is at high level; on the contrary, the water and molar ratios are at low level. In conclusion, ultrasound-assisted extraction using DES proved effective in persimmon calyx. Therefore, it can be recommended to use these environmentally friendly green solvents as an alternative to organic solvents in preparing extracts in various fields. Practical Application: This study shows the effectiveness of the ultrasound-assisted green extraction method using persimmon calyx specified as waste. These findings are compelling in the food industry in terms of consumers being now aware of green technology and the discovery that calyx is a good source of bioactive compounds.
AtıfScopus19WoS21OpenAlex23İncele - MakaleAçık Erişim2024Scopus SJRQ3Multifunctional electroless nickel boron composite coatings incorporated by magnesium diboride ceramic particles
Bülbül, Ferhat; Kara, Adem
In this study, the role of MgB2 in composite coatings is pivotal. Electroless Ni–B plating, a current-free chemical reduction process, deposits nickel–boron coatings. Other than MgB2, reinforcements like SiC, B4C, and so forth are used with Ni–B coatings for improved properties. The research focuses on Ni–B/MgB2 coatings on AISI 4140 steel using electroless deposition and annealing at different temperatures. Initially, the coating appears dense and amorphous, transforming into worm-like structures through crystallization with MgB2. Higher annealing temperatures lead to brush-like, feathery, and oyster mushroom structures, forming crystalline nickel boron compounds and oxide phases due to synergy. Interestingly, the newly introduced phases disrupt friction patterns nonlinearly, which is linked to MgB2’s ceramic nature and reinforcement quantity. Conversely, incorporating MgB2 and annealing-induced intermetallic phases notably enhances hardness (up to 6) and improves hydrophilicity and antibacterial traits in the coating.
AtıfScopus6WoS4OpenAlex4İncele - MakaleAçık Erişim2024Scopus SJRQ1Experiences of intensive care nurses providing care to the victims of Kahramanmaraş earthquakes
Çetinkaya Özdemir, Serap; Semerci Çakmak, Vahide; Ziyai, Nasibe Yağmur; Çakir, Emine
Background: Two earthquakes of magnitude 7.7 and 7.6 occurred in the Turkish province of Kahramanmaraş in 2023. The earthquakes resulted in serious losses of life and property in 11 provinces, and the injured were transferred to other provinces for treatment and care. To date, no studies on the experiences of intensive care nurses providing care to earthquake victims after the Kahramanmaraş earthquake sequence have been identified. Aim: The aim of the present study is to explore the experiences of intensive care nurses providing care to earthquake victims who were transferred to other provinces. Study Design: A qualitative descriptive research design with conventional content analysis was used. Snowball sampling was used in the selection of intensive care nurses. Data saturation was achieved with 20 nurses. In-depth interviews were conducted with the participants through phone between March 8 and March 15, 2023. MAXQDA 20 software was used for data analysis. The COREQ checklist was used to guide the reporting of the study. Results: Twenty nurses were recruited. Four themes emerged from the data: challenges in caregiving processes; psychological challenges; ethical situations; urgent need for training and support. Conclusions: After the Kahramanmaraş earthquake sequence, described by some as the disaster of the century, nurses encountered patients with unique needs that they had never encountered before and tried to cope with the constantly changing health conditions. For this reason, they were affected psychologically and experienced challenges in caregiving processes. Relevance to Clinical Practice: Conducting comprehensive training for diseases common among earthquake victims, developing new protocols for providing care to earthquake victims, developing more action plans for nurses, and psychologically supporting intensive care nurses would facilitate the caregiving processes.
AtıfScopus31WoS31OpenAlex31İncele - MakaleAçık Erişim2024Scopus SJRQ2Optimization of a Novel–Enriched Pasta Production and Its Physical, Chemical, and Characteristic Properties
Yilmaz, Merve Silanur; Kutlu, Naciye; Sakiyan, Ozge; Isci, Asli
The aim of the study is to enrich pasta with cornelian cherry powder, a product with high bioactive contents. In this way, it was aimed to obtain a new product that is more nutritionally advanced and can contribute to the country’s economy. In this study, cornelian cherry with high bioactive content and an attractive color advantage was used for the enrichment of the pasta formulation. In addition, the pasta production procedure was revised by applying microwave technology for drying. Cornelian cherry powder:dough ratio, dough thickness, and microwave power were optimized with response surface methodology. Total phenolic content, antioxidant activity, color, and water-holding capacity were determined as responses. Optimum conditions were found as 4.53% for powder:dough ratio, 0.1 cm for dough thickness, and 270 W for microwave power. According to optimization results, it was detected that the cornelian cherry powder:dough ratio affected the total phenolic content and antioxidant activity, and microwave power was found to be effective only on antioxidant activity. For optimum conditions, the total phenolic content and antioxidant activity were found as 1.29 GAE/g and 0.5 mg TE/g, respectively. The characterization analysis showed that the microwave–dried sample shrank less than those dried with the conventional method. In Fourier transform infrared spectroscopy (FTIR) results, it was determined that the amount of carbohydrates in the samples obtained under optimum conditions was lower than that of control. It has been observed that the application of microwave technology for drying pasta enriched with cornelian cherry powder had positive effects on the quality of the final product.
AtıfScopus2WoS2OpenAlex2İncele - MakaleYayıncıda açık erişim2024Scopus SJRQ1Can Enzymatic Modified Pectin in Mediterranean Fruits Be Therapeutic Against Stomach Cancer?
Üstün, Selime; Kizil, Hamit Emre; Dertli, Enes
The aim of this study was to evaluate the cytotoxic effects of enzymatically modified pectin products derived from grapefruit, jujube, and kumquat on the MKN-45 gastric cancer cell line in vitro. FTIR analysis revealed that the spectra of the pectins produced were comparable to those of commercial pectin and included the characteristic peaks identified in the literature. The galacturonic acid content was measured as 612 mg/g in grapefruit pectin, 544 mg/g in jujube pectin, and 704 mg/g in kumquat pectin. DSC analysis indicated that all pectin samples and their modifications exhibited one endothermic peak and one exothermic peak. Cytotoxicity assessments revealed that the enzymatically modified grapefruit pectin demonstrated significant cytotoxic effects across all tested concentrations, with 0.075 mg/mL being the most effective. For kumquat pectin, all tested concentrations showed cytotoxic properties, with 0.3, 0.15, and 0.075 mg/mL being the most effective. In the case of jujube pectin, cytotoxic effects were observed at all concentrations except for 1.2 mg/mL.
AtıfScopus3WoS3OpenAlex3İncele - MakaleAçık Erişim2024Scopus SJRQ2Green synthesis of (S)-1-(furan-2-yl)propan-1-ol from asymmetric bioreduction of 1-(furan-2-yl)propan-1-one using whole-cell of Lactobacillus paracasei BD101
Bülbül, Ali Savaş; Şahin, Engin
Chiral heterocyclic alcohols are important precursors for production of pharmaceutical medicines and natural products. (S)-1-(furan-2-yl)propan-1-ol ((S)-2) can be used production of pyranone, which can be used in the synthesis of sugar analogues, antibiotics, tirantamycines, and anticancer drugs. The synthetic approaches for (S)-2, however, have substantial difficulties in terms of inadequate enantiomeric excess (ee) and gram scale synthesis. Moreover, the biocatalytic synthesis of (S)-2 is unknown until now. In this study, the synthesis of (S)-2 was carried out by performing the asymmetric bioreduction of 1-(furan-2-yl)propan-1-one (1) using the Lactobacillus paracasei BD101 biocatalyst obtained from boza, a grain-based fermented beverage. (S)-2 was obtained with >99% conversion, >99% ee, and 96% yield under the optimized conditions. Furthermore, in 50 h, 8.37 g of 1 was entirely transformed into (S)-2 on gram scale (96% isolated yield, 8.11 g). This is the first report on the high-gram scale biocatalyzed synthesis of enantiopure (S)-2. These data suggest that L. paracasei BD101 can be used to bioreduction of 1 in gram scale and efficiently produce (S)-2. Furthermore, these findings laid the base for future study into the biocatalytic production of (S)-2. It was particularly notable as it was the highest known to date optical purity of (S)-2 generated by asymmetric reduction using a biocatalyst. This work offers a productive environmentally friendly method for producing (S)-2 using biocatalysts.
AtıfScopus10WoS10OpenAlex12İncele - MakaleYalnız künye2024Scopus SJRQ3Physicochemical Characteristics, Phenolic Components, and Antioxidant Capacities of Lavender Honey (Lavandula Spp.) from Isparta Region of Türkiye
Kolayli, Sevgi; Can, Zehra; Kara, Yakup; Ozkok, Aslı; Ozmert Ergin, Sema; Kemal, Mehmet; Demir Kanbur, Esra
Lavender honey is one of the most desirable blossom honeys for its unique taste and aromatic qualities and can vary significantly from one region to another. In this study, melissopalynological, physicochemical and antioxidant properties of lavender honey from the Isparta region of Türkiye were investigated. The ration of the Lavandula spp. pollen were identified ranging from 9 % to 76 % in the thirteen samples. The average pH, conductivity, moisture, Hunter Lab* and proline values were 3.72, 0.22 mS/cm, 17.17 %, L*: 66.56, a*: 66.32, b*:18.41 and 576.92 mg/kg, respectively. The average F+G and F/G were 67.66 % and 1.02, respectively. The average of total phenolic (TP) and flavonoid (TF) substance were found to be 39.40 mg GAE/100 g and 3.23 mg QUE/100 g, respectively. The average total antioxidant capacity (FRAP) and DPPH radical scavenging activity values were found to be 178.28 μmol FeSO4 ⋅ 7H2O/100 g and 53.09 mg/mL, respectively. In the phenolic component analysis performed with HPLC-PDA, p-OH-benzoic acid, p-coumaric acid, chrysin and pinocembrin were detected as common polyphenols in the samples. Conclusively, despite considerable variability in their monofloral characteristics, no significant differences were observed in the physicochemical and antioxidant properties of lavender honeys.
AtıfScopus18WoS16OpenAlex18İncele - MakaleAçık Erişim2024Scopus SJRQ3Green Synthesis of Selenium Nanoparticles using Green Coffee Beans: An Optimization Study
Baluken, Pınar; Kamiloglu, Aybike; Kutlu, Naciye
In this study, ultrasonication extraction of some bioactive compounds from green coffee beans was optimized with the response surface method using Box-Behnken experimental design. The best condition was selected as 90.90 W ultrasonic power, 33.63 min sonication time and 30 % solid concentration. The responses obtained under optimum conditions had TPC, DPPH and CUPRAC values identified as 6603.33±2025.94 ppm GAE, 9638.31±372.17 ppm TE and 98.83 mmol, respectively. Microwave-assisted selenium nanoparticle production was carried out using the extract obtained under optimized conditions. The produced selenium nanoparticles showed absorbance between 350–400 nm. The surface morphology and size of the nanoparticles were determined by transmission electron microscopy (TEM) and spherical nanoparticles of about 100 nm were produced. Functional groups affecting the reduction were determined by FTIR analysis. In addition, the produced selenium nanoparticles had amorphous (non-uniform) structure and could maintain their stability at high temperatures.
AtıfScopus5WoS5OpenAlex5İncele