Sürdürülebilir Kalkınma Amaçları

• 1

Yazarlar

• Ecem Bayram, Nesrin(2)
• Gercek, Yusuf Can(2)
• Basturk, Fatma Nur(1)
• Bayram, Nesrin Ecem(1)
• Bayram, Sinan(1)
• Bayyiğit, İshak(1)
• Baştürk, Fatma Nur(1)
• Canlı, Deniz(1)
• Feizollahi, Sepideh(1)
• Gerçek, Yusuf Can(1)
• Gıdık, Betül(1)
• Kutlu, Naciye(1)
• Kösesakal, Taylan(1)
• Kırkıncı, Seran(1)
• Sefali, Abdurrahman(1)
• Singh, Jyoti(1)
• Yesil, Yeter(1)
• Yıldırım, Nazlıcan(1)
• Çakır, Özlem(1)
• Çelik, Saffet(1)
• Çınar Topçu, Kübra(1)
• İlhan, Gülçe(1)

• MakaleAçık Erişim2026Scopus SJRQ2/r/bayburt/12720
  Bioactive profile and mineral composition of fruit extracts from four wild hawthorn (Crataegus spp.) species

  Çakır, Özlem; Çınar Topçu, Kübra; Sefali, Abdurrahman; Bayyiğit, İshak; İlhan, Gülçe; Singh, Jyoti

  This study compared the antioxidant capacity, total phenolic content (TPC), phenolic composition, lipid oxidation level, and mineral profiles of extracts obtained from four wild hawthorn species (Crataegus tanacetifolia, C. orientalis subsp. orientalis, C. orientalis subsp. szovitsii, and C. monogyna) collected from northeastern Türkiye. Significant interspecific variations were observed in DPPH, FRAP, and CUPRAC assays. While C. monogyna had the highest reducing capacity and TPC, C. orientalis subsp. szovitsii had the highest DPPH activity. Ultra-high performance liquid chromatography coupled to tandem mass spectrometry analysis showed that catechin, epicatechin, chlorogenic acid, and quinic acid were the major phenolics, and were particularly abundant in C. monogyna. Despite having a high phenolic content, C. monogyna had the highest malondialdehyde level, indicating that phenolics alone were insufficient to fully inhibit lipid oxidation. Inductively coupled plasma-mass spectrometry mineral analysis detected high levels of K, Mg, and P in all species. Principal component analysis effectively distinguished the species based on their antioxidant, phenolic, and mineral profiles. Overall, hawthorn fruits were confirmed as valuable sources of natural antioxidants and essential minerals.

  AtıfScopus1·WoS1

  İncele
• MakaleAçık Erişim2026Scopus SJRQ3/r/bayburt/12663
  Anatomical and Phytochemical Characterization of Ranunculus pinardii and Ranunculus constantinopolitanus: LC-MS/MS-Based Bioactive Compound Profiling

  Feizollahi, Sepideh; Gercek, Yusuf Can; Canlı, Deniz; Basturk, Fatma Nur; Yesil, Yeter; Kösesakal, Taylan; Ecem Bayram, Nesrin

  The aim of this study was to characterize Ranunculus pinardii and Ranunculus constantinopolitanus species anatomically and phytochemically. In order to contribute to the taxonomic characterization of R. pinardii and R. constantinopolitanus, anatomical structures of the stem, leaf, and petiole of species were examined with light microscopy. Total phenolic-flavonoid content, antioxidant activity, total anthocyanin, total proanthocyanidin, and individual phenolic compounds of extracts prepared with different solvents were determined. The results showed that the total phenolic contents of the species had a similar range (0.09-0.45 mg GAE/g for R. pinardii and 0.01-0.44 mg GAE/g for R. constantinopolitanus), but R. constantinopolitanus exhibited higher antioxidant activity (29.28 mg TE/g). Higher individual phenolic compound recovery was achieved from R. pinardii compared to R. constantinopolitanus with all solvents, except methanol. Both species were rich in luteolin, a natural flavonoid (163.98-34417.11 µg/kg for R. pinardii and 44.93-129009.44 µg/kg for R. constantinopolitanus). These results indicate that these plants contain bioactive ingredients that may have applications in different fields, such as medicine, cosmetics, and food. In particular, the detection of luteolin compound at high levels in these species compared to other components indicates that optimization studies aimed at the recovery of luteolin are important for future research.

  İncele
• MakaleAçık Erişim2024Scopus SJRQ1/r/bayburt/11898
  Evaluation of lavender essential oils and by-products using microwave hydrodistillation and conventional hydrodistillation

  Kırkıncı, Seran; Gercek, Yusuf Can; Baştürk, Fatma Nur; Yıldırım, Nazlıcan; Gıdık, Betül; Bayram, Nesrin Ecem

  This study investigated the impact of two extraction methods, traditional hydrodistillation (TDH) and microwave-assisted hydrodistillation (MAH), on the essential oil yield and chemical profile of Lavandula angustifolia L., as well as the bioactive potential of the resulting wastewater. Essential oil composition was analyzed via GC–MS, revealing similar qualitative and quantitative profiles for both methods, with α-terpinolene and (–)borneol as major constituents. Wastewater analysis via LC–MS/MS and spectrophotometric assays demonstrated the presence of significant total phenolic content (3.29–1.78 mg GAE/g) and 32 individual phenolics (463.1 µg/kg for TDH; 479.33 µg/kg for MAH). These findings suggest that both essential oil and wastewater obtained by either method possess considerable bioactive potential, with the MAH method potentially offering advantages over TDH for essential oil extraction. Further exploration of wastewater applications in various industrial sectors is warranted.

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  AtıfScopus25·WoS22·OpenAlex22

  İncele
• MakaleYalnız künye2022Scopus SJRQ1/r/bayburt/11864
  Bioactive compounds of deep eutectic solvents extracts of Hypericum perforatum L.: Polyphenolic- organic acid profile by LC-MS/MS and pharmaceutical activity

  Bayram, Sinan; Kutlu, Naciye; Gerçek, Yusuf Can; Çelik, Saffet; Ecem Bayram, Nesrin

  Deep eutectic solvents (DESs) are known as environmentally-friendly solvents that have emerged as an alternative to conventional organic solvents in recent years. In this study, the effects of ten different DESs on the extraction of bioactive components from the Hypericum perforatum were investigated. Total phenolic content, total flavonoid content, phenolic profile (32 phenolics), organic acid profile (52 organic acids), as well as antioxidant and antimicrobial activities of H. perforatum extracts prepared using DESs and ultrasonic-assisted extraction method were determined. Total phenolic, total flavonoid content, and antioxidant activities of extracts were determined between 3.10 ± 0.86–16.64 ± 2.09 mg GA/g, 0.02 ± 0.00–12.29 ± 0.30 mg QE/g, and 8.40 ± 0.50–44.78 ± 2.66 mg TE/g, respectively. DES2 (choline chloride:ethylene glycol) and DES7 (choline chloride:lactic acid) demonstrated higher extraction success than other DESs for extracting phenolics and organic acids, respectively. DESs prepared using organic acid as hydrogen bond donor were found to have an antibacterial effect against all bacterial samples. However, the inhibitory effect against yeast-like fungi was observed in a narrower spectrum. Moreover, the results from principal component analysis also confirmed that the type of solvent used for extraction has a significant influence on the phenolics, organic acid, and other parameters. As a result, it was seen that DES components directly affect the extraction efficiency of target compounds from H. perforatum. This is a first and original report about use of DESs in extracting different bioactive components from H. perforatum.

  AtıfScopus33·WoS31·OpenAlex32

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