Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Can, Zehra(5)
- Ecem Bayram, Nesrin(3)
- Akar, Zeynep(2)
- Cakir, Ozlem(2)
- Ercisli, Sezai(2)
- Kara, Yakup(2)
- Kutlu, Naciye(2)
- Ozkok, Aslı(2)
- AKMEŞE, Osman(1)
- AYGÜL, İmdat(1)
- Akar, Bulent(1)
- Akin, Meleksen(1)
- Akmeşe, Osman(1)
- Alyafei, Mohammed(1)
- Anlar, Pinar(1)
- Ay, Mizgin(1)
- Aygül, İmdat(1)
- BALTACI, Cemalettin(1)
- Baltacı, Cemalettin(1)
- Baltas, Niniet(1)
- Bayram, Nesrin Ecem(1)
- Bayram, Sinan(1)
- Birinci, Ceren(1)
- Cinemre, Sedanur(1)
- Demir Kanbur, Esra(1)
- Dramicanin, Aleksandra M.(1)
- Durul, Melekber Sulusoglu(1)
- Duzgun, Azer Ozad(1)
- Elbir, Tugba(1)
- Erdoğan, Yaşar(1)
- Erdoğan, Ümmügülsüm(1)
- Erturk, Omer(1)
- Eyduran, Sadiye Peral(1)
- FIDAN, Muhammed Said(1)
- Fidan, Muhammed Said(1)
- Gercek, Yusuf Can(1)
- Gidik, Betul(1)
- Gueven, Sara Altun(1)
- Gıdık, Betül(1)
- Hayat, Faisal(1)
Yayınlar
- MakaleYayıncıda açık erişim2026Scopus SJRQ3Effects of phenolic-standardized Crataegus orientalis flower extract on honey bee colony development and seasonal honey yield; [Efectos del extracto floral de Crataegus orientalis estandarizado en compuestos fenólicos sobre el desarrollo de colonias de abejas melíferas y el rendimiento estacional de miel]
Erdoğan, Yaşar; Erdoğan, Ümmügülsüm
Aim of study: The aim of this study was to evaluate the effects of a phenolic-standardized flower extract from Crataegus orientalis Pall. on honey bee colony development and end-of-season honey yield under field conditions, and to assess its lasting colony-level effects. Area of study: The study was conducted during the 2025 beekeeping season at the apiary of Bayburt University Beekeeping Application and Research Center, located in northeastern Türkiye. Material and methods: Twenty-four initially balanced honey bee (Apis mellifera L.) colonies were randomly assigned to four groups (n = 6): a control group receiving 1:1 sucrose:water syrup and three treatment groups receiving 50, 100, or 200 mg GAE L⁻¹ of phenolic-standardized Crataegus orientalis flower extract. Colonies were fed daily for 21 days in early spring and monitored at seven time points (T0–T6) from mid-May to late August. Colony development was assessed using brood area (cm²) and number of frames with bees, while hive-front dead bees were recorded as a safety indicator. Net honey yield was determined at the end of the season. Main results: Daily syrup consumption did not differ among groups (P > 0.05), whereas daily phenolic intake increased in a dose-dependent manner (P < 0.05). Brood area increased significantly with dose and was generally higher in the high-dose group than in the control group throughout the season (P < 0.001). No significant differences were observed among groups for seasonal averages of frames with bees or mortality index; however, a significant treatment × time interaction was detected for frames with bees. Net honey yield was significantly higher in the high-dose group compared to the control group (P < 0.01). Research highlights: Short-term early spring supplementation with phenolic-standardized Crataegus orientalis flower extract supported brood development without increasing adult bee mortality. This early developmental advantage resulted in a measurable improvement in end-of-season honey yield under field conditions.
- MakaleAçık Erişim2026Scopus SJRQ3Chemical Profiling of Stachys cretica subsp. anatolica Rech. f. (Endemic) Essential Oils and their Methanol Extracts with Evaluation as Enzyme Inhibitors, Antioxidant, and Antimicrobial Agents
Öz, Mehmet; Fidan, Muhammed Said; Baltacı, Cemalettin; Akmeşe, Osman; Sefalı, Abdurrahman; Aygül, İmdat
Enzyme inhibition activities, phenolic compounds, antioxidant activities, bioactive compounds, antimicrobial activities, and chemical components of essential oil and methanol extracts obtained from the aerial parts of S. cretica subsp. anatolica were investigated. The main phenolic compounds of aerial parts were catechin, oleuropein, and epicatechin. The determined enzyme inhibitor activities highlight the potential of S. cretica subsp. anatolica as a source of bioactive compounds, particularly for carbonic anhydrase and cholinesterase inhibition. The essential oil and methanol extract exhibited remarkable activities against CA-II, AChE, and BChE, although they were less potent than standard inhibitors. The essential oils generally showed stronger antimicrobial activity compared to the 30% methanol extracts across most bacterial and fungal strains, as evidenced by minimum lethal concentration (MLC) and lower minimum inhibitory concentration (MIC) values and larger inhibition zones. Chloramphenicol used alone exhibited the highest antimicrobial efficacy, with the lowest MIC and MLC values and the largest inhibition zones. The essential oils of S. cretica subsp. anatolica were determined as esters, oxygenated sesquiterpenes, and aldehydes in aerial parts. The main components were found to be hexahydrofarnesyl acetone in the aerial parts.
AtıfScopus3WoS3OpenAlex1
İncele - MakaleYayıncıda açık erişim2025Scopus SJRQ2Sustainable Optimization of Ohmic Heating–Assisted Extraction of Polyphenolics from Goji Berry (Lycium barbarum L.): LC–MS/MS Profiling and Blueness–Greenness Assessment
Kantar, Harun; Ecem Bayram, Nesrin
This study aimed to extract bioactive compounds from goji berry (Lycium barbarum L.) fruit using the ohmic heating–assisted extraction (OHAE) method and optimize the extraction conditions. In this context, firstly, the extraction conditions to be applied for the OHAE method were determined using the response surface method (RSM)-Box Behnken experimental design. During the study, temperature, holding time, and electrical field strength were determined as independent variables, while the total phenolic compound (TPC), total flavonoid compound (TFC), and antioxidant activity (DPPH) were selected as dependent variables. As a result of the optimization, the optimum conditions were determined to be 60 °C for the temperature, 60 min for the holding time, and 45 V/cm for the electrical field strength, and the composite desirability value of the model was 0.90. The highest experimental results for TPC, TFC, and DPPH were found to be 23.83 mg GAE/g, 7.33 mg QE/g, and 24.53 mg TE/g, respectively. In addition, the polyphenolic profiles of all extracts obtained under different process conditions were determined by LC–MS/MS, and rutin was the phenolic detected at the highest rate in the extracts. In addition, the blueness and greenness of the analytical method used in this study were evaluated using the BAGI and ComplexGAPI metrics, respectively. The results indicate that OHAE is an effective and sustainable method for extracting bioactive compounds from goji berries.
AtıfScopus5WoS5OpenAlex4İncele - MakaleAçık Erişim2025Scopus SJRQ2Optimization of Phenolic Compound Extraction from Bee Products via Solvent Systems and PCA Integration
Birinci, Ceren; Kara, Yakup; Gıdık, Betül; Kolaylı, Sevgi; Can, Zehra
To achieve a highly selective and sensitive analysis of phenolic compounds in bee products (honey, bee bread, and propolis), a simultaneous quantification of 25 phenolic compounds was performed using high-performance liquid chromatography coupled with a diode array detector. In the study, various solvents were utilized to enhance the phenolic profile of bee products, including pH 2 and 7 ultra-pure water, diethyl ether, and ethyl acetate. These included non-liquid–liquid extraction, pH 2 with 10 mL of pure water and 20 mL of diethyl ether; pH 2 with 10 mL of pure water and 20 mL of ethyl acetate; pH 2 with 10 mL of pure water, 10 mL of diethyl ether, and 10 mL of ethyl acetate; and pH 7 with 10 mL of pure water, 10 mL of diethyl ether, and 10 mL of ethyl acetate. Additionally, the integration of phenolic compounds identified through the enrichment method was pursued using principal component analysis (PCA). The extraction yields and recovery rates of phenolic compounds can be significantly improved by combining and integrating different extraction techniques. Our results demonstrated that using different solvent combinations significantly improved both the yield and diversity of phenolic compounds extracted from the complex matrices of bee products.
AtıfScopus2WoS2OpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ2Enzyme inhibitory, antioxidant, antimicrobial activities, and phenolic profiles of the methanol extract of Gelasia sericea an endemic species
AYGÜL, İmdat; AKMEŞE, Osman; SEFALI, Abdurrahman; BALTACI, Cemalettin; ÖZ, Mehmet; FIDAN, Muhammed Said
This study aimed to investigate, for the first time, the phytochemical composition, antioxidant, antimicrobial, and enzyme inhibitory properties of the methanolic extract of Gelasia sericea (Aucher ex DC.) Zaika, Sukhor. & N.Kilian. The extract demonstrated a moderate yield (6.55 g/100 g dry plant material) and was found to be rich in phenolic acids, particularly ferulic acid (17182.97 μg g-1), followed by caffeic acid, protocatechuic acid, and p-coumaric acid. Antioxidant analyses revealed high total phenolic (388.86 mg GA eq./100 g), total flavonoid (74.03 mg QE eq./100 g), and total antioxidant capacity (503.33 mg AA eq./100 g). The extract exhibited remarkable ABTS radical scavenging activity (95.99%, IC50 = 37.59 mg ml-1) and considerable ferric-ion reducing power (974.78 mg FeSO4 eq./100 g). Antimicrobial assays indicated moderate inhibitory effects, with stronger activity against Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis) and the yeast Candida albicans, whereas Gram-negative bacteria were less susceptible. The extract’s MIC values ranged between 0.20-3.25 mg ml-1, and MLC values between 0.41-6.50 mg ml-1, which were higher than those of standard antibiotics. Enzyme inhibition assays revealed moderate activity against carbonic anhydrase II (IC50 = 0.0136 µg ml-1) and weak inhibition of cholinesterases and α-glucosidase, while α-amylase inhibition was relatively more pronounced (IC50 = 13350.00 µg ml-1). Overall, these findings highlight G. sericea as a valuable natural source of phenolic acids and antioxidants, with promising potential for applications in functional foods, nutraceuticals, and phytopharmaceuticals. However, the relatively limited antimicrobial and enzyme inhibitory activities suggest the need for further studies on bioavailability, in vivo efficacy, and compound isolation to optimize its practical applications.
- MakaleYalnız künye2025Scopus SJRQ2Bee bread from Anatolia: its chemical composition, phenolic and aromatic profiles, and antioxidant properties
Kolayli, Sevgi; Okumus Yukunc, Gulsah; Kara, Yakup; Demir Kanbur, Esra; Can, Zehra; Ozkok, Aslı; Tanugur Samanci, Aslı Elif
This study investigated the botanical origin, chemical composition, phenolic and volatile aromatic profiles, and antioxidant activities of 11 bee bread samples from different regions of Anatolia, Turkey. The bee bread samples contained high amounts of proteins (19.61 g/100 g) and lipids (6.43 g/100 g). The bee breads were determined to have a rich mineral content. The antioxidant potential of the bee breads was predicted using total phenolic content (TPC), total flavonoid content (TFC), total condensed tannin (TCT) content, 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP) assays. The TPC of the bee breads ranged between 2.041 ± 0.170 and 3.224 ± 0.006 mg GAE/g, while the TFC ranged from 0.323 ± 0.004 to 1.903 ± 0.017 mg QE/g. The FRAP assay showed antioxidant activity ranging from 17.778 ± 0.207 to 49.752 ± 0.856 µmol FeSO4.7H2O/g, and the DPPH values were between 1.054 ± 0.009 and 4.366 ± 0.014 SC50 mg/mL. Using 25 standards, RP-HPLC-PDA quantified the composition of the phenolic compounds, attributed to their antioxidant activity. The highest concentrations were detected for t-cinnamic acid, rutin, and p-coumaric acid. One hundred nineteen volatile aromatic compounds were determined in the bee breads by solid-phase microextraction coupled with gas chromatography and mass spectrometry (SPME-GC-MS). The obtained values suggest that bee breads could serve as a potential source of nutrients and bioactive compounds for value-added food supplements and functional foods.
AtıfScopus12WoS13OpenAlex15İncele - MakaleAçık Erişim2025Scopus SJRQ1Optimization of Ethanol Extraction Conditions From Sun-Dried Apricot and Prediction of Antioxidant, Phenolic, and Flavonoid Contents and Their Effects on HCT116 Cells Using Artificial Neural Networks
Topcu, Kubra Cinar; Gueven, Sara Altun; Cakir, Ozlem; Anlar, Pinar; Durul, Melekber Sulusoglu; Ay, Mizgin; Alyafei, Mohammed; Hayat, Faisal; Ercisli, Sezai
This study aimed to optimize the ethanol extraction conditions of sun-dried apricot (Prunus armeniaca L.) and evaluate the antioxidant capacity, phenolic, and flavonoid contents of the obtained extracts. Response surface methodology (RSM) was applied to determine the optimal extraction conditions, which were identified as 60 degrees C temperature, 34% ultrasonic power, 46 min sonication time, and a 4 g/mL solid-liquid ratio. Under these conditions, the extract exhibited a total phenolic content (TPC) of 4.20 mg GAE/g, a total flavonoid content (TFC) of 7.09 mg QE/g, a DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging capacity of 1.37 mg TE/g, a ferric reducing antioxidant power (FRAP) value of 9.12 mg TE/g, and a thiobarbituric acid reactive substances (TBARS) level of 1.69 mg MDA/g. The artificial neural network (ANN) model provided highly accurate predictions for these parameters. Additionally, cell culture experiments demonstrated that the extract exerted a dose-dependent cytotoxic effect on HCT116 colon cancer cells, significantly reducing their viability. These findings highlight the potential of sun-dried apricot extracts as natural antioxidants with possible applications in the functional food and pharmaceutical industries.
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İncele - MakaleYalnız künye2023Scopus SJRQ1Comparison of bioactive constituents by HPLC–DAD–ESI-MS and UFLC and in vitro antioxidant activities of blossom honey, bee pollen, and propolis
Saroğlu, Öznur; Ecem Bayram, Nesrin; Özçelik, Beraat
The aim of this study was to analyze the total phenolic content, phenolic profile, and antioxidant activity of honey, bee pollen, and propolis samples from Turkey's Black Sea Region. The total phenolic content of these bee products was found using Folin–Ciocalteu's method, and their antioxidant capacity was found using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and cupric ion reducing antioxidant capacity (CUPRAC) assays. Phenolic compounds of honey samples were characterized by high-performance liquid chromatography coupled to a photodiode array detector and mass spectrometer (HPLC–DAD–ESI-MS), while phenolic compounds of bee pollen and propolis samples were quantified ultra-fast liquid chromatography (UFLC). The total phenolic values for honey, bee pollen and propolis were 6.32–18.21 mg GAE/100 g, 547.64–769.4 mg GAE/100 gr, and 6096.1–11,564 mg GAE/100 gr, respectively. DPPH and CUPRAC values of honey, pollen and propolis were 11.05–21.38% and 0.38–1.48 µmol Trolox/g; 24.67–38.63% and 0.03–0.05 mmol Trolox/g; 11.81–34.12% and 0.47–0.89 mmol Trolox/g, respectively. About 30 different phenolic compounds were identified as quantitative. Our findings have shown that all bee products examined in the study are found to contain gallic acid, naringenin, and caffeic acid. In terms of total phenolic content and antioxidant activity, the bee product extracts were ranked as follows: propolis > bee pollen > honey. The high concentration of phenolic compounds in propolis explains its remarkable antioxidant effect.
AtıfScopus10WoS10OpenAlex10İncele - MakaleYalnız künye2022Scopus SJRQ3Optimization of Ultrasound Extraction of Phenolic Compounds from Tarragon (Artemisia dracunculus L.) Using Box–Behnken Design
Kutlu, Naciye; Kamiloglu, Aybike; Elbir, Tugba
In this study, ultrasound extraction of bioactive compounds from tarragon was examined as a sustainable technology. Pure water, which is a green solvent, was used as solvent. Box–Behnken was used in the experimental design, and ultrasonic power, extraction time and solvent-to-sample ratio were determined to be independent variables. The physicochemical properties were determined by physical (color, pH, Brix) and chemical analyses (antioxidant activity, total flavonoid and total phenolic compound (TPC)) in the extracts obtained under different conditions. Optimum conditions were found to be 73.9% ultrasonic power, 43.2 min sonication time and 10 mL/g solvent-to-sample ratio. The composite desirability (R2) of optimum conditions was 99.3% after optimization. Since high efficiency was obtained in a short time with ultrasound extraction, it was found to be quite good in terms of energy savings. That is, the highest TPC was obtained with a sonication time of 45 min with this method, while similar TPC in the control group (maceration) was obtained in 24 h. In the optimum conditions, extraction with other green solvents (ethanol and deep eutectic solvent—DES) was carried out and bioactive compound yields were compared. For different solvents compared under optimum conditions, ethanol gave higher yields in terms of TPC, while higher yields were obtained in samples using water as solvent for some antioxidant activity values. The results obtained with DES were not as high as expected, and this resulted in the conclusion that a hydrogen bond donor is not suitable for obtaining bioactive compounds from tarragon.
AtıfScopus9WoS9OpenAlex9İncele - MakaleAçık Erişim2021Scopus SJRQ3Honey: Determination of volatile compounds, antioxidant and antibacterial activities
Karlidag, Semiramis; Keskin, Merve; Bayram, Sinan; Mayda, Nazlı; Ozkok, Aslı
Honey is an important functional food for human health and nutrition that is collected by honey bees and stored in the honeycombs. In this study, total phenolic content, antioxidant activity and volatile compounds of 13 different honey samples collected from various districts of Malatya province were investigated. As a result of this study, it was determined that the total phenolic content varied between 8.50 mg GAE 100 g–1 and 73.90 mg GAE 100 g–1 and it was observed that the honey samples were rich in aldehydes, aliphatic acid and esters, alcohols, hydrocarbons, carboxylic acid esters, ketones, terpenes, fatty acids and esters. In addition, the antibacterial effects of honey samples were determined against 18 different pathogenic bacteria using agar well diffusion (AWD) method, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). In AWD assay, it was recorded that inhibition zone diameters varied between 9 mm and 14 mm and honey samples were found to have a partial inhibitory effect against selected target pathogens.
AtıfScopus5WoS3OpenAlex7İncele - MakaleAçık Erişim2021Scopus SJRQ3A study on free-radical scavenging activity, individual phenolic compounds and element concentration of propolis; [Propolisin serbest radikal temizleme aktivitesi, bireysel fenolik bilesik içerigi ve element konsantrasyonu üzerine bir çalisma]
Ecem Bayram, Nesrin
The aim of this study was to assess the quality of five propolis samples obtained from Turkey (TP), China (CP), Brazil (BP1, BP2), and Ethiopia (EP). The phenolic compounds of the propolis were identified and quantified using the liquid chromatography-tandem mass spectrometry technique (LCMS/ MS). In addition, quality parameters such as total flavonoid content, total phenolic content, freeradical scavenging activity and element contents were investigated. As a result of LC-MS/MS analysis, the extracts were sorted as TP> BP1> BP2> CP> EP in terms of the total concentration of individual phenolic compounds. Chlorogenic acid was determined as the dominant compound in BP1 and EP, pcoumaric acid as the dominant compound in the BP2 and trans-ferulic acid as the dominant compound in the samples from CP and TP. The concentration of DPPH was higher in TP whereas the ABTS concentration was almost similar to other propolis extracts. The contents of potassium (K), calcium (Ca), iron (Fe), magnesium (Mg) and sodium (Na) in the propolis samples were in the range of 2416.75- 14416.02 mg/kg, 8.52-613.25 mg/kg, 102.66-1425.82 mg/kg, 523.84-7336.74 mg/kg and 57.65-191.15 mg/kg, respectively. Consequently, it is again supported that chemical characteristics and activity of propolis varies according to its geographical origin with this study.
AtıfScopus1OpenAlex3İncele - MakaleAçık Erişim2021Scopus SJRQ1Extraction of Phenolic Compounds from Cornelian Cherry (Cornus mas L.) Using Microwave and Ohmic Heating Assisted Microwave Methods
Kutlu, Naciye; Isci, Asli; Sakiyan, Ozge; Yilmaz, Asim Egemen
In this study, it was aimed to extract bioactive compounds (phenolics and anthocyanins) from cornelian cherry (Cornus mas L.) using microwave (ME) and ohmic heating assisted microwave extraction (OH-ME) as an alternative to maceration (M). Total phenolic compound (TPC), total monomeric anthocyanin content (TMAC), antioxidant activity (AA), water-soluble solid matter (WSSM), color values, and pH of the extracts were determined. The effect of extraction time, solid to solvent ratio, microwave power, electrical field strength, and holding time during ohmic heating on extraction characteristics was investigated for different methods. Ohmic heating application prior to extraction has enhanced the TPC yield by 1.1 and 5.4-folds compared to that of ME and M, respectively. Moreover, the extraction time was decreased by approximately 42 and 95% as regards ME and M, respectively. The highest TMAC value (0.65 mg cya-3-glu/g dry matter) was observed with OH-ME. The experimental data obtained by ME and OH-ME methods was fitted to the Peleg model to describe the TPC yields. These results indicate that the combined application of ohmic heating and microwave extraction is a potential alternative method for total phenolic compounds extraction from cornelian cherry due to increased yields and reduced extraction times.
AtıfScopus48WoS40OpenAlex47İncele - MakaleAçık Erişim2021Scopus SJRQ1Phenolic and free amino acid profiles of bee bread and bee pollen with the same botanical origin - similarities and differences
Bayram, Nesrin Ecem; Gercek, Yusuf Can; Çelik, Saffet; Mayda, Nazli; Kostic, Aleksandar Z.; Dramicanin, Aleksandra M.; Özkök, Asli
In this study, the chemical profile of bee pollen (BP) and bee bread (BB) samples collected from the same beehive were analyzed by LC-MS/MS (liquid chromatography technique coupled with tandem mass spectrometry), providing the identification of 23 phenolic compounds and 42 free amino acids (FAAs). Rutin was the phenolic compound with the highest rate of occurrence in both BP and BB samples. However, concentrations of protocatechuic acid, 2,5-dihydroxybenzoic acid and kaempferol compounds were significantly higher in BB samples than in BP samples from the same hive probably as result of microbial activity and glycosides degradation. The obtained data revealed that the phenolic profiles of the samples differ not only by the type of a product but also by region. Among FAAs proline was the predominant compound in all the analyzed BP and BB samples followed by L-asparagine (BP samples) and L-aspartic acid (BP and BB samples). A high content of proline can be used as a parameter of sample freshness. Also, Principal Component Analysis (PCA) and Cluster analysis proved the possibility of using phlorizin as a chemotaxonomic marker for Rosaceae (Malus or Prunus genus) pollen presence in BP1 sample. In addition, amino acid profile had higher impact on BP and BB sample differentiation due to lower FAAs content in BB samples probably caused by microbial activity. To the best of our knowledge, this study is the first to compare the individual phenolic compounds and free amino acids of bee pollen and bee bread samples with the same botanical origin (predominantly originated from plants belonging to the following families: Asteraceae, Fabaceae, Plantaginaceae and Rosaceae). (C) 2021 The Author(s). Published by Elsevier B.V. on behalf of King Saud University.
AtıfScopus103WoS92OpenAlex114İncele - MakaleAçık Erişim2020RP-HPLC-UV Analysis of the Phenolic Compounds, Antimicrobial Activity Against Multi-Drug Resistant Bacteria and Antioxidant Activity of Fruit and Seed of Diospyros lotus L.
Akar, Zeynep; Karakurt, Aylin; Okumus, Funda; Cinemre, Sedanur; Duzgun, Azer Ozad; Akar, Bulent; Can, Zehra
The object of the present study was to investigate the antioxidant, antimicrobial activity and phenolic compounds of fruit and seeds of Diospyros lotus L. The fruits consumed by humans as nutrients were harvested from the plants that grow naturally in the province of Trabzon-Akçaabat, Eastern Black Sea Region of Turkey. The antioxidant activities of fruit and seeds of Diospyros lotus were determined by using four methods (% DPPH radical scavenging activity, FRAP antioxidant power determination, CUPRAC reducing antioxidant activity and total phenolic content (TPC) in five different proportion of methanol-water extracts. All extracts of fruit and seeds of D. lotus analyzed through whole antioxidant analysis methods showed significant antioxidant activity. In addition, antimicrobial activity of fruit and seeds extracted with DMSO was determined against seven standard bacteria and three multi-drug resistance clinical strains. Although fruit extracts did not have the antimicrobial activity against bacteria, seeds showed antimicrobial effect to both standard strains (Gram-negative and Gram-positive) and antibiotic resistance clinical isolates (Klebsiella pneumoniae carrying blaKPC, Acinetobacter baumannii, harboring blaOXA-23 gene and resistance to colistin, and multi-drug resistant Pseudomonas aeruginosa). MICs’ value of plant seed extracts for standard strains was 0.75-25 mg/mL and antibiotic resistant clinical bacteria were 12.5 and 25 mg/mL. Additionally, phenolic compounds in methanol extracts of fruit and seeds were also determined in by HPLC using 19 standards. Gallic acid and chrysin phenolic compounds were the major phenolic compounds in fruit and seeds, respectively.
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İncele - MakaleYalnız künye2019Scopus SJRQ4DETERMINATION OF ANTIOXIDANT, ANTIMICROBIAL ACTIVITIES, PHENOLIC COMPOUNDS OF WILD ROSA L. SPECIES BAYBURT, TURKEY
Gidik, Betul; Akar, Zeynep; Can, Zehra; Sefali, Abdurrahman; Erturk, Omer
Five different rosehip (Rosa L.) species including, Rosa canina, Rosa iberica Stev, Rosa villosa, Rosa beggeriana Schrenk and same kind of but different location Rosa spinosissima grown in Bayburt from Turkey are studied. The wild species of Rosa L. were collected from Rocks and Steps, Field and garden borders. Morphological parameters were measured as fruit and seed weights and fruit and seed size. Ten fruits were chosen randomly for the measurement and take the average of them to determine the weights and size. In our study was determined antioxidant activity, antimicrobial activity and phenolic compounds. As antioxidant activity; total phenolic total flavonoid, condense tannin contents, CUPRAC, FRAP, ABTS. Nineteen standard of phenolic compositions of fruits and seeds were determined. Antioxidant, antimicrobial activities of the extracts were found high levels in rose hip species fruit than seed. Catechin, rutin protocatequic acid and CAPE were principal for all rose hip species fruit but, was not deteceted CAPE Kop Mountain, Yukari Kop Village Rosa spinosissima species. This suggests that the difference in location affects the phenolic content. Pearson Correlation analyze has done with the morphological parameters, GPS data, antioxidant activity and phenolic compounds by using the SPSS software programme version 25.0.
AtıfWoS3İncele - MakaleYalnız künye2019Scopus SJRQ4Some edible forest fruits their in vitro antioxidant activities, phenolic compounds and some enzyme inhibition effects
Okan, Onur Tolga; Serencanr, Huseyin; Baltas, Niniet; Can, Zehra
The purpose of the study was to analyze the po-tential health-pro mo ting components of some edible forest species of fruits. These are Service tree (Sor-bus domestica), Black rosehip (Rosa pimpinelli-folia), Red rosehip (Rosa carina), Bay fruit {Lawns nobilis), Cornelian cherry (Cornus mas), Autumn-olive (Elaeagrtus umbellate), and two different blue-berry fruits (Vaccinium arctostaplylos and Vaccin-ium myrtillus). In the present study, chemical and an-tioxidant activities, phenolic compounds as well as, inhibition effects on important enzymes (acetylcho-linesterase, xanthine oxidase and urease) of fruits were studied. Total polyphenol, flavonoid content, and the in-vitro antioxidant activity were evaluated by DPPH and FRAP. The sugar contents and phe-nolic compounds of the fruits were analyzed by HPLC-RJD and HPLC-UV. Fruits was determined the total polyphenol content (TPC) 1.10 to 19.87 mgGAE/g, total flavonoid content (TFC) 0.01 to 0.80 mgQE/g, DPPH values 0.22 to 6.03 mg/mL and FRAP values 4.24 to 168. 02 umol FeSO47H2O/g. All samples were determined various rate fructose and glucose. HPLC-UV revealed fruits contained different phenolic compounds. Inhibition values of the enzymes were expressed as inhibition concentra-tion (IC50: Mg/mL or ug/mL). It can be concluded that edible forest fruits are a potential source of anti-oxidants with therapeutic importance as well a natu-ral enzyme inhibitor.
AtıfScopus15İncele - MakaleYalnız künye2016Scopus SJRQ3PHYTOCHEMICAL PROFILES OF WILD GROWN BLACKBERRY AND MULBERRY IN TURKEY
Akin, Meleksen; Eyduran, Sadiye Peral; Ercisli, Sezai; Yilmaz, Ilker; Cakir, Ozlem
Blackberry and mulberry are main berry crops grown in Black Sea region mostly in humid shade forest areas and its important for local people's diet and also important for the maintenance of their health and prevention of disease. Present study aimed to determine the content of vitamin C, organic acids (citric acid, tartaric acid, oxalic acid, malic acid, succinic acid, fumaric acid), sugars (glucose and fructose) and phenolic compounds (catechin, rutin, quercetin, chlorogenic acid, ferulic acid, o-coumaric acid, p-coumaric acid, caffeic acid, syringic acid, vanillic acid, and gallic acid), as well as antioxidant capacity (Trolox Equivalent Antioxidant Capacity, TEAC assay) in the wild grown blackberry and mulberry fruit. Among phenolic acids, chlorogenic acid was the predominant for all wild grown blackberries, white and black mulberries. The presence of oxalic acid was only detected in the wild blackberry genotype. As a result, the phytochemical recognition of the wild grown blackberry, black and white mulberries might contribute to forthcoming investigations for developing the efficiency of food industry.
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