Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ1Optimization of Ethanol Extraction Conditions From Sun-Dried Apricot and Prediction of Antioxidant, Phenolic, and Flavonoid Contents and Their Effects on HCT116 Cells Using Artificial Neural Networks
Topcu, Kubra Cinar; Gueven, Sara Altun; Cakir, Ozlem; Anlar, Pinar; Durul, Melekber Sulusoglu; Ay, Mizgin; Alyafei, Mohammed; Hayat, Faisal; Ercisli, Sezai
This study aimed to optimize the ethanol extraction conditions of sun-dried apricot (Prunus armeniaca L.) and evaluate the antioxidant capacity, phenolic, and flavonoid contents of the obtained extracts. Response surface methodology (RSM) was applied to determine the optimal extraction conditions, which were identified as 60 degrees C temperature, 34% ultrasonic power, 46 min sonication time, and a 4 g/mL solid-liquid ratio. Under these conditions, the extract exhibited a total phenolic content (TPC) of 4.20 mg GAE/g, a total flavonoid content (TFC) of 7.09 mg QE/g, a DPPH (2,2-diphenyl-1-picrylhydrazyl) radical scavenging capacity of 1.37 mg TE/g, a ferric reducing antioxidant power (FRAP) value of 9.12 mg TE/g, and a thiobarbituric acid reactive substances (TBARS) level of 1.69 mg MDA/g. The artificial neural network (ANN) model provided highly accurate predictions for these parameters. Additionally, cell culture experiments demonstrated that the extract exerted a dose-dependent cytotoxic effect on HCT116 colon cancer cells, significantly reducing their viability. These findings highlight the potential of sun-dried apricot extracts as natural antioxidants with possible applications in the functional food and pharmaceutical industries.
AtıfScopus2WoS2OpenAlex2
İncele - MakaleAçık Erişim2021Scopus SJRQ1Seed-propagated summer apples: Great morphological and biochemical diversity
Karatas, Neva; Ercisli, Sezai; Bozhuyuk, Mehmet Ramazan; Cakir, Ozlem; Necas, Tomas; Ondrasek, Ivo
The northeastern Anatolia region of Turkey is one of the richest plant biodiversity areas in Turkey. This study describes some important tree and fruit characteristics of 20 seed-propagated summer apple genotypes from northeastern Anatolia using morphological and biochemical markers. The genotypes were evaluated morphologically for tree growth habit, ripening date, fruit weight, fruit firmness, fruit shape, fruit color, fruit taste, juiciness and aroma. The biochemical characteristics measured were organic acids, SSC (soluble solid content), titratable acidity, vitamin C, total phenolic content and antioxidant capacity. We found significant differences for most of the morphological and biochemical characteristics. The genotypes exhibited quite diverse harvest dates ranging from 4 July to 16 August. Summer apple genotypes had fruit weight between 101.9 g and 133.5 g. The genotypes had diverse fruit shapes, including round, conic and oblate, and over fruit colours such as pink, red, yellow and green. Genotypes GUM7 and GUM13 stood out for fruit weight, SSC, total phenolic and antioxidant capacity. GUM7 and GUM13 present dissimilarity from the other genotypes. While the first showed a lower average fruit weight, SSC, total phenolic content and antioxidant capacity, the second revealed higher average of fruit weight, total phenolic content, antioxidant capacity and higher SSC. Due to their favorable characteristics, GUM13 can be used for further crosses with genotypes of other groups, which also present favorable characteristics.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2017Scopus SJRQ2Morphological, Biochemical and Antioxidant Properties of Local Loquat (Eriobotrya Japonica (Thunb.) Lindl.) Germplasm from Turkey; [Morphologische, biochemische und antioxidative Eigenschaften des Zuchtmaterials der Japanischen Wollmispel (Eriobotrya Japonica (Thunb.) Lindl.) aus der Türkei]
Akbulut, Mustafa; Gozlekci, Sadiye; Ercisli, Sezai; Cakir, Ozlem
Loquat (Eriobotrya japonica L.) grown well for commercial purposes in subtropical regions nearly 30 countries and originated from China. The most important loquat producers in the world are China, Spain, Turkey, Pakistan, India, Italy and Brazil. In this study, ten pre-selected promising loquat genotypes sampled from eastern Black region and analyzed for their important morphological, biochemical and antioxidant characteristics. The standard cultivar ‘Sayda’ is also included in the study. The results indicated differences for all of the morphological, biochemical and antioxidant characteristics among tested genotypes. Fruit mass and fruit flesh percentage of the genotypes ranged from 35.40 g (LOQ-8) to 46.90 g (LOQ-5) and from 79.40 (%) to 86.32 (%) indicating some local genotypes had higher fruit mass and fruit flesh percentage than standard cultivar ‘Sayda’. Total phenolic content was the highest as 263 μg GAE/g in LOQ-7 genotype while the lowest in LOQ-8 genotype (185 μg GAE/g). LOQ-7 genotype had the highest total antioxidant capacity. Local genotypes in general have higher total phenolic, total carotenoid, vitamin C and antioxidant activity than cv. ‘Sayda’.
AtıfScopus3WoS5OpenAlex4İncele - MakaleYalnız künye2016Scopus SJRQ3PHYTOCHEMICAL PROFILES OF WILD GROWN BLACKBERRY AND MULBERRY IN TURKEY
Akin, Meleksen; Eyduran, Sadiye Peral; Ercisli, Sezai; Yilmaz, Ilker; Cakir, Ozlem
Blackberry and mulberry are main berry crops grown in Black Sea region mostly in humid shade forest areas and its important for local people's diet and also important for the maintenance of their health and prevention of disease. Present study aimed to determine the content of vitamin C, organic acids (citric acid, tartaric acid, oxalic acid, malic acid, succinic acid, fumaric acid), sugars (glucose and fructose) and phenolic compounds (catechin, rutin, quercetin, chlorogenic acid, ferulic acid, o-coumaric acid, p-coumaric acid, caffeic acid, syringic acid, vanillic acid, and gallic acid), as well as antioxidant capacity (Trolox Equivalent Antioxidant Capacity, TEAC assay) in the wild grown blackberry and mulberry fruit. Among phenolic acids, chlorogenic acid was the predominant for all wild grown blackberries, white and black mulberries. The presence of oxalic acid was only detected in the wild blackberry genotype. As a result, the phytochemical recognition of the wild grown blackberry, black and white mulberries might contribute to forthcoming investigations for developing the efficiency of food industry.
AtıfWoS8İncele - MakaleAçık Erişim2016Scopus SJRQ2Bioactive content of rose hips of different wildly grown rosa dumalis genotypes
Alp, Sevket; Ercisli, Sezai; Jurikova, Tunde; Cakir, Ozlem; Gozlekci, Sadiye
A rose hip is the fruit of a rose plant and mostly belongs to Rosa canina and Rosa dumalis. These species are genuine found as wild in natural conditions, while in some countries are cultivated for their hips that are picked and used in a wide variety of preparations. Because they contain a variety of antioxidants, carotenoids, flavonoids, polyphenols, leucoanthocyanins and catechins, rose hips are considered to be a good cancer preventative. The Rosa genus has been the focus of many recent studies due to its potential benefic effects on treatment and prevention of several diseases. However, there are few in vitro studies concerning its composition and antioxidant capacity. The aim of the present study was to determine bioactive content, including ascorbic acid, total phenolics, total flavonoids, total carotenoids and antioxidant activity of Rosa dumalis genotypes growing wild in Erzurum province located eastern Anatolia. The results revealed that fruits of Rosa dumalis different genotypes were rich rich in terms of vitamin C, which ranged from 402 to 511 mg/100 g fresh weight base. The total phenolic content varied from 297 to 403 mg/100 g fresh weight. The genotype 'E-09' had the highest total flavonoids content (229 mg quercetin equivalent/100 g fresh weight) and the lowest value was attributed to genotype 'E-04' with 143 mg/ quercetin equivalent/100 g fresh weight. The antioxidant activity of the genotypes was between 12.9-28.6 μg Trolox/ml samples. The results revealed that there was enough diversity among Rosa dumalis genotypes for bioactive content and promising genotypes, with high bioactive content, were determined, which can become study material for future breeding activities.
AtıfScopus27WoS22OpenAlex27İncele - MakaleYalnız künye2016Scopus SJRQ3Organic acids, sugars and mineral content of cherry laurel (laurocerasus officinalis roem) accessions in Turkey
Esringu, Aslihan; Akšić, Milica Fotirić; Ercisli, Sezai; Okatan, Volkan; Gozlekci, Adiye; Cakir, Ozlem
In this study we report on the content of organic acids, sugars and miner-als in the pulps of the twelve cherry laurel accessions most commonly consumedin eastern Black Sea Region. Malic acid was the dominant organic acid rangedfrom 43.27 (CL6) to 54.23 (CL3) mg/100 g fresh weight basis. The dominantsugars were glucose and fructose in the pulps that ranged from 4.83 (CL1) to5.74 (CL5) mg/100 g and 4.66 (CL3) to 5.53 (CL7) mg/100 g, respectively. Thepulp of cherry laurel was shown to be rich in potassium (187-241 mg), phos-phorus (26-45 mg), calcium (15-22 mg), magnesium (15-24 mg) and sodium(3.9-6.1 mg) in 100 g fruit pulp. The data may be useful in selecting wild ediblefruit species appropriate for incorporation into diets.
AtıfScopus5İncele - MakaleYalnız künye2015Scopus SJRQ3Biodiversity and Landscape Use of Sea Buckthorn (Hippophae rhamnoides L.) in the Coruh Valley of Turkey; [Sanddorn (Hippophae rhamnoides L.) im Coruh-Tal (Türkei): Biologische Vielfalt und Landschaftsnutzung]
Sezen, Isik; Ercisli, Sezai; Cakir, Ozlem; Koc, Aysen; Temim, Elma; Hadziabulic, Alisa
The Sea buckthorn, one of the most important wild edible fruits widely grown in Northeastern part of Turkey, is characterized by resistance to hard environmental conditions and looks spectacular, especially in autumn and winter when it is decorated with orange berries. Climatic conditions in Northern Anatolia are suitable for the growing of the Sea buckthorn, which can be encountered in various dry areas as well as by riversides. Local people traditionally processed or preserved sea buckthorn fruits (berries). The decorative sea buckthorn shrubs/trees and berries are an important element of natural landscape in Northeastern Anatolia. The aim of the study was to define the biodiversity among trees/shrubs, berries and leaves of the Sea buckthorn accessions based on morphological and biochemical data. Results showed a high diversity among accessions in terms of plant, leaf and berry characteristics. Berry diameter, length and 100 berry weight ranged from 5.48 to 7.18 mm; 6.64 to 9.14 mm and 15 to 26 g, respectively. A wide variability of berry skin colour was observed to be yellow, light yellow, dark yellow, yellow orange, orange and dark orange. The anthocyanin content varied from 7 to 38 mg/l berry juice.
AtıfScopus14WoS11OpenAlex14İncele - MakaleYalnız künye2014Scopus SJRQ4Some Physicochemical Characteristics, Bioactive Content and Antioxidant Characteristics of Non-Sprayed Barberry (Berberis vulgaris L.) Fruits from Turkey; [Physikalisch-chemische Eigenschaften, bioaktive Inhaltsstoffe und antioxidative Eigenschaften von nicht mit Pflanzenschutzmitteln behandelten Früchten der Berberitze (Berberis vulgaris L.) aus der Türkei]
Yildiz, Hilal; Ercisli, Sezai; Sengul, Memnune; Topdas, Elif Feyza; Beyhan, Omer; Cakir, Ozlem; Narmanlioglu, Haluk Kemal; Orhan, Emine
Increasing consumer demands for indigenous, non-sprayed with pesticides and less-known or “forgotten” fruits necessitate knowledge on their breeding, cultivation, biochemical content, harvesting and marketing. Anatolia is rich for wild edible fruit species and barberry is abundant throughout Anatolia. The aim of this study was to determine some important physicochemical characteristics, bioactive content and antioxidant capacity of fruits from nineteen promising barberry (Berberis vulgaris L.) genotypes grown in the Coruh valley, Northeastern Anatolia. The results indicated genotype-specific differences for most of the physicochemical characteristics, antioxidant capacity and the content of some bioactive compounds. Fruit mass ranged from 0.073 (‘Coruh-7’) to 0.267 g (‘Coruh-11’). Total phenolic content ranged from 2532 (‘Coruh-’) to 3719 mg GAE per liter fruit juice (‘Coruh-11’). The genotype ‘Coruh-12’ had the highest total monomeric anthocyanin content (1004 mg per liter fruit juice) as cyanidin-3-glucoside. The highest total antioxidant capacity was observed in fruits of ‘Coruh-8’ and ‘Coruh-9’ genotypes with all three antioxidant-determining methods. We conclude that the barberry fruits represent a good source of bioactive phytochemicals because of their high phenolic and anthocyanin contents.
AtıfScopus34WoS26OpenAlex36İncele