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Koleksiyondaki öğeler
- MakaleAçık Erişim2025Scopus SJRQ2Evaluation of Fe Content on the Fluidity of A356 Aluminum Alloy by New Fluidity Index
Durmuş, Melek; Dispinar, Derya; Gavgali, Mehmet; Uslu, Emin; Çolak, Murat
Elements that are deliberately added to aluminum alloys or are incorporated into the alloy later depending on the production process affect the final product properties. In addition, liquid metal cleaning is important in minimizing undesirable elements. Considering the production process, one of the most harmful impurities that is likely to pass into the alloy via diffusion for aluminum is the element, Fe. It is known that this is due to the fact that although Fe is highly soluble in liquid aluminum and its alloys, it has very little solubility in solids. Depending on the Fe content, mechanical properties, porosity and fluidity properties are affected in aluminum alloys. In this study, stainless and carbon steel rods were dipped into the melt at 700 °C and 750 °C for 1, 2 and 5 h. Castings were performed before and after degassing. Four-channel fluidity mold with different section thickness was used in the trials. Additionally, microstructure characterization was performed under varying casting conditions. Fluidity Index was proposed which is a single value measured from all fluidity values in different sections. When the results were examined, it was determined that the diffusion material, holding time, casting temperature and liquid metal cleanliness had an effect on the fluidity. Due to the increase in diffusion time, a decrease in fluidity was observed in both carbon steel and stainless steel. It was found that fluidity was significantly reduced when using stainless steel.
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İncele - MakaleAçık Erişim2025Scopus SJRQ3Evaluation of miR-130b-3p and miR-375 levels and telomere length with telomerase activity in prostate cancer
Karadağ, Abdullah; Dirican, Ebubekir; Özmerdiven, Çağdaş Gökhun; Özen, Ata; Ayan, Semih; Kabadere, Selda
Prostate cancer (PC) is the most frequent cancer in males, as well as the second highest cause of cancer-related deaths in men. Differences in expression levels of miRNAs were linked with prostat cancer pathogenesis. qPCR was used to evaluate the expression of miR-130b-3p and miR-375 in Benign Prostate Hyperplasia (BPH (n = 20) and PC (n = 22, pre- and post-operative) patients plasma. Relative telomere lengths (RLTs) in genomic DNA isolated from plasma were measured with qPCR, and telomerase activity analyzed by the ELISA method. PSA levels of PC patients were greater than of BPH patients (p = 0.0473). miR-130b-3p and miR-375 levels were significantly lower in pre-operative specimens of PC patients according to BPH (p = 0,0362, p = 0.0168, respectively). Similarly, post-operative miR-375 levels were lower in PC patients than in BPH patients (p = 0.1866). BPH patients had shorter RTLs than PC patients in both pre- (p=0.0438) and post-operative (p=0.0297) specimens. Telomerase activity was higher in PC patients than BPH(p = 0.0129). Interestingly, telomerase activity was further increased after surgery (p = 0.0003). We aim to identify the levels of miR-130b-3p and miR-375 expression and their relationship with telomerase activity in PC patients. Our data suggest that miRNAs and telomere length (TL) with telomerase activity may play a role in regulating prostate tumorgenesis and may be used as biomarkers for PC diagnosis.
- MakaleAçık Erişim2026Scopus SJRQ1Effects of a puppet-assisted house-tree-person test on fear and anxiety in children receiving chemotherapy and associated influencing factors: A projective, quasi-experimental study
KAHRIMAN, Ilknur; AKSOY, Bahar; KANDAZ, Ufuk; BORAN, Serpil; GÖGER, Berrin; KIRBAŞ, Zila Özlem
Objectives This study investigated the effect of the puppet-assisted House-Tree-Person Test (HTP-T) on fear and anxiety levels in children undergoing chemotherapy treatment and the factors influencing these outcomes. Methods The study employed a one-group pretest–posttest quasi-experimental design combined with HTP-T analysis. The study was conducted with 29 children aged 5–12 years receiving chemotherapy at the pediatric hematology-oncology outpatient clinics of a university hospital in the Eastern Black Sea Region of Türkiye during the 2022–2024 years. Data were collected using “the Demographic Information Form for Children and Parents, the Children's State Anxiety Scale (CSA), the Children's Fear Scale (CFS), and HTP-T". Data analysis was performed using descriptive statistics, repeated measures ANOVA, and HTP-T analysis. Results Statistically significant differences were observed in children's mean CSA (F = 3.898, p = 0.026, η2 = 0.122) and CFS (F = 5.313, p = 0.008, η2 = 0.159) scores across the pre-treatment, during-treatment, and post-treatment measurements. The HTP-T analysis revealed that children had difficulty regulating anxiety and fear, expressed concerns about family and environmental events, reported feelings of loneliness, and exhibited strong emotional attachment to their families. Conclusion The study demonstrated that incorporating puppet-assisted HTP-T during chemotherapy contributed to reducing children's fear and anxiety and offered a useful approach for identifying influencing factors. Implications for nursing practice HTP-T, a therapeutic play technique incorporating puppetry and projective methods, may be effective in reducing fear and anxiety among children undergoing chemotherapy.
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İncele - MakaleAçık Erişim2026Scopus SJRQ1Modal parameter determination and structural assessment of historical minaret under earthquake and wind loads
Yanik, Yusuf; Demirtaş, Betül; Yurdakul, Muhammet; Aymelek, Abdullah; Türker, Temel
This study presents a comprehensive linear time history of a historical masonry minaret called the Grand Mosque Minaret in Bayburt, employing a finite element (FE) model subjected to five distinct real earthquake acceleration records. Ambient vibration tests were conducted within the framework of operational modal analysis (OMA), utilizing enhanced frequency domain decomposition technique to estimate the experimental modal parameters. The FE model, developed under the assumption of linear elastic material behavior, was updated through a vibration-based model updating technique to accurately represent the dynamic characteristics of the structure. Each seismic record was applied as a base excitation, and the corresponding time-dependent structural responses were computed for initial and updated FE models. The analysis yielded critical engineering parameters, including maximum displacement and minimum–maximum principal stress distributions. The results obtained from the FE analyses were evaluated comparatively. Also in this study, the wind loads of the minaret were determined using the TS 498 standard, and structural wind load analyses were performed on the initial and updated FE models. Drift ratio values of the minaret were calculated for earthquake records and wind loads, and the structural performance of the minaret was evaluated comparatively for both models. It has been found that the structural behavior of the minaret was significantly affected by earthquakes. The drift ratio values remained within the controlled damage limit for wind analyses, while earthquake analyses indicated that the minaret was mostly in the collapse limit. The results show that more effective conservation and restoration strategies for cultural heritage structures can be developed by using both FE and experimental methods.
- MakaleAçık Erişim2025Scopus SJRQ1Seismic resilience of existing RC dual-system buildings during the 2023 Kahramanmaraş earthquakes: a case study
Tonyali, Zeliha; Kiral, Adnan; Ergun, Mustafa; Garcia, Reyes
This study investigates the seismic resilience of an existing reinforced concrete (RC) dual-system during the 2023 Kahramanmaraş earthquakes. The shear wall-frame dual building was designed according to the Turkish guidelines (TEC 2007) and experienced negligible damage during the earthquakes, whereas all neighboring buildings collapsed. The case study building is modeled in SAP2000® adopting a lumped plasticity approach. The 3D building model was subsequently subjected to pushover and nonlinear time-history analyses (NTHAs) using real ground motions recorded during the first and strongest mainshock of the Kahramanmaraş earthquakes ((Formula presented.) = 7.7 Pazarcik earthquake). The results from the NTHAs indicate that the maximum inter-story drift (IDR) ratios on all floors of the case study building remained below the Immediate Occupancy performance level (IDR = 1.0%). Moreover, the dual-system building designed with TEC 2007 survived the earthquakes without damage, even when the design earthquake scenarios exceeded those considered in the new and more stringent TBEC 2018 (i.e. a 475 return period). The limited damage experienced by the RC dual-system building can be largely attributed to its high wall index (WI = 1.5% and 1.84%) and high average lateral stiffness index (H/T ≥45.3), which are above the minimum values (ρ = 0.6% and H/T ≥45) suggested in previous research. This study also highlights the critical importance of site-specific ground motion selection, particularly in the context of Hatay province, where the seismic demands exhibited significant variability and intensity. This study contributes to a better understanding of the resilience of RC shear wall-frame buildings in seismic zones.
AtıfScopus13WoS12OpenAlex16İncele - MakaleAçık Erişim2025Scopus SJRQ3Application of the entropy based COPRAS model in determining the most appropriate irrigation systems for agricultural enterprises producing maize
Ulay, Göksel; Peker, Hüseyin; Ayata, Ümit
Synthetic-based furniture varnish (colorless and glossy) was applied in two coats using a brush to the following wood types: lemon (Citrus limon (L.) Burm.), black pine (Pinus nigra Arnold), kotibé (Nesogordonia papaverifera), iroko (Milicia excelsa Welw. C.C. Berg), and loquat (Eriobotrya japonica Lindl.). The color parameters [b*, ho, L*, a*, and C*, ∆a*, ∆L*, ∆C*, ∆H*, ∆b*, and ∆E*] of the varnished and unvarnished surfaces were compared. The analysis of variance results for all color parameters revealed significant effects for wood type, varnish application, and their interaction. When the ∆E* values derived from color formulas were sorted from the lowest to the highest, they were ordered as follows: lemon, black pine, kotibé, loquat, and iroko. After varnish application, decreases in L* values were observed across all wood types, while increases in b* and C* values were detected. In black pine wood, the a* and ho values increased. Additionally, for iroko, loquat, and kotibé woods, there was an increase in the a* parameter, while ho values decreased for these wood types. Overall, the varnish application resulted in color changes in the wood materials.
- MakaleAçık Erişim2025Scopus SJRQ1Anticancer (cytotoxic, anticlonogenic, antimetastatic, immunomodulatory actions) properties of 3,5-dibromosalicylaldehyde against glioblastoma cells and DFT analyses (FT-IR, Raman, NMR, UV) as well as a molecular docking study
Karakaş Sarıkaya, Ebru; Pehlivanoğlu, Suray; Türkmen, Merve Özcan; Ekincioğlu, Yavuz; Kostak, Feyza; Çelik, Sultan; Dereli, Ömer
Background Information: The primary objectives of this study were to characterize 3,5-dibromosalicylaldehyde (3,5-DBSA) and, investigate its antiproliferative, antimetastatic, cytotoxic, and immunoregulatory properties. NMR, Raman, UV, and FT-IR spectroscopies were used to characterize 3,5-DBSA. Potential conformations of 3,5-DBSA were evaluated using Spartan's MMFF method. Geometry optimization calculations using Gaussian software calculated conformation energy values. Results: Subsequently, Raman, FT-IR, UV (ethanol) and NMR (DMSO) parameters were calculated. The experimental spectrum was compared to theoretical spectroscopic data. The present investigation investigated 3,5-DBSA's anticancer properties; therefore, docking was done once the stable structure had been identified. Conclusion: Identifying stable structure is crucial to molecular docking studies. In order to identify the mechanism by which 3,5-DBSA binds to PI3K as a therapeutic target, molecular docking was utilized. This work is the first to show that 3,5-DBSA is cytotoxic, anticlonogenic, antimetastatic, and immunomodulatory in glioblastoma cell line U87MG compared to healthy fibroblast L929 cells. Cytotoxicity and anti-clonogenicity studies investigated 3,5-DBSA's antiproliferative activities, whereas wound healing assays assessed cell migration. The immunomodulatory effects of 3,5-DBSA in glioblastoma were assessed by measuring Netrin-1 and IL-6 protein levels. According to our findings, 3,5-DBSA may treat glioblastoma. Significance: This work analyzes 3,5-DBSA's conformational search, characterization, molecular docking, and structural and anticancer properties.
- MakaleYalnız künye2025Scopus SJRQ4Tunable optoelectronic performance of ZnO-Coated TiO2 nanowires for enhanced UV photodetection
Sarac, M.F.; Solakyildirim, T.; Teber, A.
In this study, vertically aligned TiO2 nanowires (NWs) were fabricated on titanium (Ti) foil via thermal oxidation and subsequently coated with zinc oxide (ZnO) using zinc acetate solutions of 25, 50, and 100 mM concentrations. Structural and optoelectronic properties were systematically investigated using SEM, XRD, XPS, PL, UV-Vis, and I-V analyses. SEM results confirmed a progressive ZnO surface coverage, with complete encapsulation observed at 100 mM. EDS analysis revealed a Zn content increase from 0.81 wt.% (25 mM) to 8.43 wt.% (100 mM), accompanied by a decrease in Ti content from 70.78 wt.% to 49.02 wt.%. XRD patterns showed distinct ZnO peaks for coated samples, while XPS confirmed Zn2+ and Ti4+ states with minimal interdiffusion. Optical bandgap values increased slightly with ZnO concentration: 3.04 eV (pure TiO2), 3.06 eV (25 mM), 3.05 eV (50 mM), and 3.11 eV (100 mM), attributed to enhanced crystallinity and heterojunction formation. PL spectra showed increasing green luminescence (∼520 nm) with ZnO content, indicating rising defect-related recombination. Electrical measurements showed a sharp rise in photocurrent from 3.67 × 10−6 A (pure TiO2) to 4.74 × 10−4 A (100 mM). Correspondingly, responsivity (R) increased from 0.020 to 2.168 mA/W and detectivity (D*) from 8.5 × 108to 7.56 × 109 Jones. These results demonstrate that ZnO coating substantially enhances light absorption, charge separation, and carrier transport properties of TiO2 NWs. The optimized 100 mM ZnO-TiO2 heterostructure offers high-performance UV photodetection potential for environmental sensing, wearable optoelectronics, and aerospace technologies.
AtıfOpenAlex1İncele - MakaleAçık Erişim2025Scopus SJRQ3Examining the Criteria Affecting Corporate Social Responsibility in Businesses from the Consumer Perspective Using the Pythagorean Fuzzy Entropy Technique; [İşletmelerde Kurumsal Sosyal Sorumluluğu Etkileyen Kriterlerin Pisagor Bulanık Entropi Tekniğiyle Tüketici Perspektifinden İncelenmesi]
Keskin, Abdulkadir; Kiraçli-Leblebicioğlu, Nilüfer; Keskin, Abdurrahman; Leblebicioğlu, Burak
Corporate social responsibility (CSR) serves as a self-regulation mechanism for businesses and a framework for consumers to evaluate companies. Carroll's (1991) CSR pyramid categorises these responsibilities, which can differ depending on cultural and economic contexts. This study examines Corporate Social Responsibility (CSR) in the context of Carroll's pyramid from the perspective of Turkish consumers, based on expert interviews analysed using the “Pythagorean Fuzzy Entropy” method. The results reveal that Turkish consumers prioritise businesses' “economic” responsibilities the most, followed by “philanthropic” responsibilities. “Ethical” responsibilities are ranked slightly lower, with “legal” responsibilities considered the least important in this context.
AtıfScopus1OpenAlex2TR Dizin1
İncele - MakaleYalnız künye2026Scopus SJRQ1Resilience-oriented seismic retrofit of heritage masonry minarets using hybrid base isolation and supplemental damping
Ergun, Mustafa; Tonyali, Zeliha; Kiral, Adnan; Elias, Said
Historic masonry mosques represent a highly vulnerable class of cultural heritage structures whose seismic fragility stems from their complex geometries, heterogeneous material composition, and rigid load-transfer mechanisms. This study presents a resilience-oriented seismic performance improvement of the historic masonry minaret of the Bayburt Grand Mosque, a structure with limited lateral deformation capacity that challenges the applicability of conventional strengthening measures. To address this limitation, a hybrid retrofitting strategy is introduced, integrating lead rubber bearings (LRBs) with supplemental viscous dampers (VDs) at the foundation level. This combined system—implemented for the first time in a historic masonry minaret—aims to enhance energy dissipation and displacement control through a minimally invasive and architecturally compatible approach. Finite element analyses (FEA), coupled with MATLAB-supported optimization routines, were used to calibrate isolator stiffness and damper coefficients. Three configurations were evaluated: fixed-base, LRB-isolated, and hybrid LRB–VD systems. Nonlinear time-history analyses (NTHAs) using the 1992 Erzincan (Otlukbeli) earthquake record quantified displacements, stress–strain responses, and damage progression. Results show that while base isolation mitigates seismic demand, it remains insufficient under restricted deformation capacity. The proposed hybrid system reduces peak horizontal displacements from 22 cm to 12 cm, limits drift ratios below 0.17 %, and lowers maximum tensile stresses from 4.890 MPa to 0.490 MPa—well below the masonry tensile strength of 0.880 MPa. Two iterative analytical design methodologies are additionally introduced to derive effective isolator stiffness and viscous damping coefficients, enabling systematic integration into resilience-focused evaluation frameworks. Overall, the study advances reliability-based, conservation-compatible retrofitting practices for historic masonry minarets and supports sustainable strategies for seismic risk mitigation.
AtıfScopus8WoS7OpenAlex6İncele - MakaleAçık Erişim2026Scopus SJRQ1Determination of complex permittivity of a thin low-loss dielectric sample using state-space approach from waveguide measurements
Hasar, Ugur C.; Ali, Husain; Kaya, Yunus
An extraction procedure is proposed for relative complex permittivity () determination of thin low-loss samples positioned/deposited on a supporting substrate material using waveguide non-resonant microwave measurements. Its substrate thickness and sample thickness independence makes it unique extraction method in comparison with the available retrieval methods which are free from either substrate thickness information only or sample thickness information only. Its theoretical model is constructed on the state-transition matrix and state vector through which the link between and measured scattering (S-) parameters is established. Compared with previous works in the literature, a closed form (explicit) expression of is derived for a two-layer (sample on a substrate material) composite structure, thereby eliminating any numerical analysis or tool. Numerical analyses are implemented for validation of the proposed method as well as assessing the effect of noise and any possible air gap between the sample and its substrate. X-band ( GHz) waveguide measurements of a thinner (around 1.00 mm) polyvinyl chloride (PVC) for different measurement scenarios and measurements of a thin zinc oxide film (m) were performed to evaluate the performance of the proposed extraction method against other similar methods in the literature. Our method can find applications for characterization of thin-film, radar-absorbent material coatings, anti-corrosive paints, or thermal barrier coatings where sample thickness (and substrate thickness) can vary from one sample to another from the same batch.
- MakaleAçık Erişim2025Scopus SJRQ2Determining errors in force measurements for colloids close to contact
Yücel, Harun
Due to diffraction patterns in light microscopy, the overlapping of colloid images introduces minor errors in determining particle positions, which affecting the accuracy of observing interactions between colloids near contact. This study quantitatively investigates the errors arising from the overlapping effect in force measurements between two closely positioned colloids using digital video microscopy (DVM). For this aim, computer simulations were conducted to obtain the positions of two optically trapped colloids interacting based on a force model and particle images were generated as a time series using experimental particle intensity profiles for two different particle sizes. These generated images were analyzed using tracking algorithms from the literature and the interaction forces were extracted and compared with theoretical force values. The results demonstrated that diffraction patterns significantly influence the accuracy of particle position detection and interaction force calculations. Large diffraction patterns and intensity fluctuations in an image introduce significant errors. However, these errors can become significantly smaller in the presence of large forces and may therefore be considered negligible.
- MakaleAçık Erişim2025Scopus SJRQ2The Effect of Health Literacy Level of Caregivers of Individuals With Diabetes on Care Activities and Supportive Behaviours
Semerci Çakmak, Vahide; Akeren, Zahide; Sönmez Sarı, Ebru; Kalyoncuo, Servet
Background: To determine the effect of the health literacy levels of caregivers of individuals with T2DM on caregiving activities and supportive behaviours. Methods: Cross sectional study. The sample for the study comprised of people who provided care for 442 individuals who were diagnosed with diabetes. The data were collected using the Personal Information Form, HLS-14 and D-CASS. Descriptive statistics, Independent samples t test, One-Way ANOVA and multiple linear regression analysis were used to analyse the data. Results: According to the results of the multiple linear regression analysis, the model was found to be statistically significant, and the variables that were incorporated into the model were able to explain 68.1% of the variance. Among the variables included in the model, HLS-14, educational status, employment status, income status and diabetes-related education were found to affect the care activities and supportive behaviours of caregivers of individuals with diabetes. Conclusion: In the research, it was determined that care activities and supportive behaviours were higher in those with higher levels of HL, higher levels of education, those who were not employed, those with higher income levels, and those who received education about diabetes. Nurses should develop training programmes to increase the HL levels of caregivers.
AtıfScopus2WoS2OpenAlex3İncele - MakaleAçık Erişim2025Scopus SJRQ1Metabolic syndrome index measurement tool (MSI): scale development, reliability and validity study
Akeren, Zahide; Apaydın, Emine
Aim: Identifying the risks of metabolic syndrome (MetS) can lead to early targeted interventions and thus contribute to improved quality of life by reducing the risk of developing MetS, diabetes or heart disease in the future. We aimed to develop a valid and reliable measurement tool to measure the MetS risk of the population. Materials and methods: In the methodological study, an item pool was created by reviewing the literature. Pre-application was performed after the weighting of the items whose content validity was ensured by taking expert opinions. Data were collected from 43 patients with MetS from a state hospital affiliated to the Ministry of Health and 405 individuals without MetS from the community, from a total of 448 individuals using the Individual Information Form, Finnish Diabetes Risk Scale (FINDRISC) and Metabolic Syndrome Index (MSI). The data obtained were evaluated using SPSS 22.0 and MedCalc 19.1 statistical programmes. Scale discrimination was analyzed by independent samples t-test between the upper and lower 27% groups. The cut-off point of the scale score in predicting the diagnosis of MetS was tested by ROC analysis. Correlation analysis was performed with the parallel form for criterion validity. Results: As a result of the ROC analysis, a perfectly compatible scale with a sensitivity of 100%, a specificity of 85.43% and a cut-off score of 48 was obtained. When the correlation analyses between MSI and FINDRISC scores were examined for criterion validity, a positive moderate (r = 0.632, p < 0.001) correlation was found between FINDRISC and MSI. When the discrimination of the scale was analysed, it was found that there was a significant difference between the lower 27% and upper 27% groups (p < 0.05) and it was revealed that the MSI made sensitive measurements to discriminate. Conclusions: The MSI scale is a valid and reliable tool for early detection of MetS risk.
AtıfScopus2WoS2OpenAlex2İncele - MakaleAçık Erişim2026Scopus SJRQ1Non-Destructive Intelligent Microwave Sensing of Water Content in Sand–Water Mixtures Using S-Parameter Features and PLS Regression
Çakır, Mehmet
The accurate and rapid estimation of water content in granular materials is important for geotechnical engineering, construction-material evaluation, agricultural monitoring, and non-destructive material assessment. This study presents a controlled laboratory feasibility framework for estimating water content in sand–water mixtures using microwave S-parameter measurements and physically interpretable features. Sixty measurements were acquired from six nominal mixture levels containing 0%, 5%, 10%, 15%, 20%, and 25% water by mass using a WR-229 waveguide-based fixture over 3.30–4.90 GHz. Descriptors were extracted from the raw and empty-reference-normalized S11 and S21 responses, including extrema, slopes, area-based indicators, band-averaged values, selected-frequency responses, and phase statistics. Ridge regression, partial least squares regression, support vector regression, Gaussian process regression, random forest, and gradient boosting regression were evaluated. The selected PLS model achieved RMSE = 3.56%, MAE = 2.92%, and R2 = 0.826 under leave-one-mixture-level-out group-wise cross-validation, which was used as the primary indicator of generalization to an unseen mixture level. The substantially lower error obtained under repeated-measurement leave-one-out cross-validation primarily reflects within-level repeatability under controlled conditions and should not be interpreted as evidence of universal calibration performance. The results demonstrate that magnitude- and phase-derived microwave descriptors, particularly transmission-based features, provide an interpretable and repeatable framework for water-content estimation under the specific sand type, sample geometry, water source, and laboratory conditions investigated. Further validation using independent preparation batches, different granular materials, measured water conductivity, temperature variation, and field-like conditions is required before practical deployment.
- MakaleAçık Erişim2025Scopus SJRQ2Detailed investigation of the spectroscopic features of nicardipine hydrochloride using experimental and quantum chemical methods
Can, Sumeyra; Cinar, Mehmet; Baris, Ozlem
Context: The structural and spectroscopic properties of drug groups can be determined using spectroscopic techniques and quantum chemical calculations. In this study, the structural and spectroscopic properties of nicardipine, a potent calcium channel blocker belonging to the dihydropyridine drug group, were investigated. For this purpose, FT-IR, Raman, NMR, and UV–Vis spectra of nicardipine hydrochloride were recorded. The ground state geometry optimization performed under vacuum conditions showed excellent agreement with X-ray diffraction (XRD) data, with root-mean-square deviations of bond lengths and bond angles calculated as 0.017 Å and 2.2°, respectively. Vibrational spectrum analysis revealed all characteristic modes, and theoretical B3LYP predictions largely agreed with experimental data. NMR spectra recorded in chloroform solvent confirmed the molecular structure of nicardipine. A comparison with previously reported data revealed significant differences in the proton NMR results, while the carbon NMR data showed consistency. The gauge-invariant atomic orbital (GIAO) method, commonly used for NMR spectrum prediction, yielded results within an acceptable error range despite minor inconsistencies arising from differences between experimental and computational conditions. In the UV–Vis spectrum of nicardipine HCl, an absorption peak corresponding to π-π* excitation was observed at 238 nm. Method: The geometric optimizations and vibration spectra of the nicardipine drug molecule were performed using the Gaussian 09 program with the B3LYP functional and the 6–311 + + G(d,p) basis set. Visualizations were performed using the GaussView 5.0 interface program. NMR spectra were recorded in chloroform solvent using the GIAO method. Molecular electrostatic potential (MEP) maps and Mulliken atomic charges were analyzed to gain deeper insight into the electronic properties.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYayıncıda açık erişim2026Scopus SJRQ1Social Media-based Interventions to Promote Physical Activity in People with Disabilities: A Systematic Review
Yarımkaya, Erkan; Oğur, Yekta Göksel; Aydemir, Uğur
Purpose: This systematic review summarized and evaluated 13 studies investigating the effectiveness of social media-based interventions to promote physical activity (PA) among people with disabilities (PWD). Methods: Findings regarding study, participant and intervention characteristics, and PA outcomes were extracted. The methodological quality of the studies was assessed using the Crowe Critical Appraisal Tool. Results: Findings regarding the effectiveness of social media-based interventions to promote PA among PWD varied, and provide the support for social media-based PA intervention benefits for people with autism spectrum disorder, attention deficit hyperactivity disorder, physical disability, and cancer patient; however, there was no support for its use in people with developmental coordination disorder. Conclusion: Social media-based interventions may have the potential to promote PA among PWD. However, to fully leverage this potential, further research is needed. This review provides valuable insights for researchers, parents, and educators seeking to promote PA among PWD.
- MakaleAçık Erişim2026Scopus SJRQ4The Effect of Postural Mobility Exercises on the Athletic Performance Success, Proprioceptive Sense and Various Strength Parameters of Traditional Archers; [Postüral Mobilite Egzersizlerinin Geleneksel Okçuların Sportif Performans Başarı, Proprioseptif Duyu ve Çeşitli Kuvvet Parametrelerine Etkisinin İncelenmesi]
Kul, Murat; Hazar, Emre Berk; Boz, Emre; Uçal, Muhammed Salih
The aim of this study is to investigate the effects of eight weeks of TheraBand-based postural mobility exercises on athletic performance, strength, and proprioceptive senses in traditional Turkish archers (TTA). The study involved 24 male volunteer athletes enrolled at Bayburt University who had at least six months of regular archery training history. Participants were divided into experimental and control groups; the experimental group underwent postural mobility exercises three days a week for eight weeks, while the control group continued only their routine archery training. Data collection included assessments of grip and squeeze strength, back-leg strength, shoulder proprioception, shoulder mobility, and TTA shooting performance. The findings showed that the experimental group achieved significant improvement in all parameters, while the control group showed only limited increases in shoulder mobility and archery performance (p < .05). In conclusion, adding TheraBand exercises to traditional training is recommended as an effective method for increasing archers' muscle strength, joint stability, and performance.
- MakaleAçık Erişim2025Scopus SJRQ2Investigation of the Effects of Filling Speed, Casting Temperature and Metallurgical Quality on Fluidity of Lamellar Graphite Cast Iron at Different Section Thicknesses
Köse, Sami; Çolak, Murat; Şüküroğlu, Ebru Emine
In this study, the fluidity properties of the alloy were investigated at different casting temperatures, different section thicknesses, and varying casting parameters of lamellar graphite cast iron materials. To achieve our goal, we utilized sand molds that were created with specific parameters including pouring temperature, metallurgical quality, section thickness, and fluidity test model. These molds were used for casting. Thus, the effect of fluidity properties in changing casting conditions and liquid metal advance distances at determined section thicknesses was investigated. Modeling was carried out with FlowCast casting simulation software by determining the liquid metal advance distance depending on the section thickness in the castings made in sand molds under changing casting conditions. The fluidity and advance distance of the liquid metal was determined comparatively with experimental and modeling techniques under the changing casting conditions in the parameters determined in this study. When the outcomes were examined; it was observed that different liquid metal advance distances occur at different cross-section thicknesses depending on the changing conditions.
AtıfScopus8WoS8OpenAlex7İncele - MakaleYalnız künye2026Scopus SJRQ4Microwave assisted green synthesis of nano-sized biogenic silver in extract of Phlomis linearis: potential anticancer and antimicrobial activities
Orçan Çayır, İlayda; Tahta, Beyhan; Cömertpay, Sabahattin; Uruş, Serhan; Bülbül, Ali Savaş; Aygan, Ashabil; Aksan, Mehmet Emrah
Silver nanoparticles (AgNPs) are known for their significant anticancer and antimicrobial activities in the field of medicine. In the present study, AgNPs were synthesized using a microwave-assisted green synthesis process, in which Ag(I) ions were reduced by organic compounds extracted from the leaves and stems of Phlomis linearis, an endemic plant which acted as both reducing and stabilizing agents. Although various species of the Phlomis genus have been studied in the literature, the synthesis of the nano-sized biogenic silver with reducing Ag(I) in the extract of the endemic plant P. linearis is reported here for the first study time, along with the evaluations of its bioactive properties. The obtained AgNPs were characterized by optical, structural, morphological, etc. techniques such as Ultraviolet–visible spectroscopy (UV–Vis.), Fourier-Transform Infrared Spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray (EDX), transmission electron microscopy (TEM), dynamic light scattering (DLS), and photoluminescence (PL). Gas chromatography − mass spectrometry (GC–MS) and FT-IR techniques were used in order to evaluate the biochemical-reduction mechanism. When their antimicrobial activities were determined by the well diffusion method on six bacterial strains, the results showed that P. linearis exhibited antimicrobial activity against all tested bacteria. Additionally, the investigation of the anticancer activity of the particles by using the MTS method on a breast cancer cell line (MCF-7) and a healthy human cell population (human umbilical vein endothelial cells [HUVEC]) revealed that our AgNPs were more cytotoxic toward the cancerous cells compared to the non-cancerous ones (p < 0.001).
