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Koleksiyondaki öğeler
- MakaleAçık Erişim2026Scopus SJRQ3Analysis of the Impact of Blue Stain on the Color, Glossiness, and Whiteness Properties of Scots Pine Lumber
Ayata, Ümit; Peker, Hüseyin; Ulay, Göksel; Çamlıbel, Osman; Atilgan, Abdi
It is known that blue stain causes a loss of price value for Scots pine wood in the wood trade due to the visual defects it creates. In this study, color parameters [red color tone (a*), lightness (L*) value, yellow (b*) color tone, tone angle (h°) value, and chroma (C*) value], whiteness index (WI*) values, and glossiness measurements [at angles of 20°, 60°, and 85°] were compared in Scots pine (Pinus sylvestris L.) wood with normal and blue rot conditions. According to the color parameters obtained, it was determined that the L* value decreased by 11.43%, a* by 79.95%, b* by 28.86%, and C* by 32.75%, while the h° value increased by 17.74%. With the blue coloration, decreases were observed in the 20° glossiness values measured in the ⃦ and ⊥ directions, while increases were observed in the 60° and 85° glossiness values measured in the ⃦ and ⊥ directions. With the blue coloration, decreases of 12.86% in the ⊥ direction and 29.87% in the ⃦ direction in the WI* values were observed. According to these results, it was determined that the wood material with the blue coloration disease had a darker color.
- MakaleAçık Erişim2026Scopus SJRQ1Gastrointestinal stability and bioactivity of propolis from diverse origins
Can, Zehra; Çelebi, Zeynep Berin; Tunca, Erol; Kolaylı, Sevgi; Sevin, Sedat; Tutun, Hidayet
Propolis is a chemically complex bee product whose biological properties depend on its botanical and geographical origin. However, little is known about how gastrointestinal digestion affects its phenolic profile and bioactivity. In this study, twelve propolis samples from eight countries were evaluated for phenolic and flavonoid contents, antioxidant capacity (FRAP, ABTS+•), and urease inhibition before and after simulated gastric digestion. RP-HPLC–PDA identified 26 phenolic compounds showing substantial compositional diversity. Turkish Bolu propolis retained the highest post-gastric FRAP value, while several samples (BBP, AFP) maintained or enhanced urease inhibition. PCA and HCA highlighted origin-dependent differentiation, identifying digestive stability as a key variable for functional potential.
AtıfOpenAlex2
İncele - MakaleAçık Erişim2026Scopus SJRQ1Finite element analysis driven optimization of an electrodynamic levitation system with permanent magnet Halbach arrays
Ozkat, Erkan Caner; Abdioglu, Murat; Ozturk, U. Kemal
This study presents a finite element analysis (FEA)-driven optimization for the design of an electrodynamic levitation (EDL) system incorporating permanent magnet Halbach arrays (PM-HAs). The primary objective is to maximize the net force difference between lift (Fy) and drag (Fx) forces under realistic physical and manufacturing constraints. The nonlinear electromagnetic behavior of the EDL system is modeled using high-fidelity FEA, capturing the complex interaction between the PM-HA and a conductive plate. At each iteration of the population-based optimization algorithm, full magnetoquasistatic simulations are performed to ensure a physically accurate evaluation of key performance metrics. A comprehensive parametric study involving 256 distinct PM-HA configurations reveals a non-monotonic relationship between the number of magnets and levitation performance, highlighting the critical role of magnetic field distribution. Configurations with 9 to 11 magnets achieve the highest net levitation force. The optimization results indicate that the optimal configuration includes four horizontally aligned permanent magnets (PMs) with a width of 74.00 mm and three vertically aligned PMs with a width of 74.67 mm, along with a 7 mm thick conductive plate having a conductivity of 5 ×107 S/m. This design delivers a maximum lift force of 3550 N and a minimum drag force of 279 N at 100 m/s. The findings demonstrate that effective EDL system design requires a carefully arranged magnet configuration rather than a simple maximization of magnet count or size. The proposed FEA-guided framework offers a robust and scalable methodology for the optimization of high-performance Maglev systems.
- MakaleYayıncıda açık erişim2025Scopus SJRQ2Sustainable Optimization of Ohmic Heating–Assisted Extraction of Polyphenolics from Goji Berry (Lycium barbarum L.): LC–MS/MS Profiling and Blueness–Greenness Assessment
Kantar, Harun; Ecem Bayram, Nesrin
This study aimed to extract bioactive compounds from goji berry (Lycium barbarum L.) fruit using the ohmic heating–assisted extraction (OHAE) method and optimize the extraction conditions. In this context, firstly, the extraction conditions to be applied for the OHAE method were determined using the response surface method (RSM)-Box Behnken experimental design. During the study, temperature, holding time, and electrical field strength were determined as independent variables, while the total phenolic compound (TPC), total flavonoid compound (TFC), and antioxidant activity (DPPH) were selected as dependent variables. As a result of the optimization, the optimum conditions were determined to be 60 °C for the temperature, 60 min for the holding time, and 45 V/cm for the electrical field strength, and the composite desirability value of the model was 0.90. The highest experimental results for TPC, TFC, and DPPH were found to be 23.83 mg GAE/g, 7.33 mg QE/g, and 24.53 mg TE/g, respectively. In addition, the polyphenolic profiles of all extracts obtained under different process conditions were determined by LC–MS/MS, and rutin was the phenolic detected at the highest rate in the extracts. In addition, the blueness and greenness of the analytical method used in this study were evaluated using the BAGI and ComplexGAPI metrics, respectively. The results indicate that OHAE is an effective and sustainable method for extracting bioactive compounds from goji berries.
AtıfScopus5WoS5OpenAlex4İncele - MakaleAçık Erişim2025Scopus SJRQ1Disrupted miRNA Biogenesis Machinery Reveals Common Molecular Pathways and Diagnostic Potential in MDS and AML
Çevik, Kenan; Ay, Mustafa Ertan; Tombak, Anıl; Ay, Özlem İzci; Karakaş, Ümit; Erdal, Mehmet Emin
Background: Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are clonal stem cell disorders in which disrupted post-transcriptional regulation contributes to aberrant hematopoiesis and leukemic transformation. The miRNA biogenesis machinery, which comprises Drosha, DGCR8, Dicer, TARBP2, and AGO1, ensures the precise maturation of miRNAs that control lineage commitment and proliferation. However, the extent to which alterations in this pathway reshape hematopoietic gene networks during myeloid disease evolution remains largely unexplored. Methods: Bone marrow samples from newly diagnosed, untreated MDS and AML patients and matched healthy controls were analyzed for the expression of five key miRNA biogenesis genes using quantitative real-time PCR. Statistical comparisons, correlation matrices, and ROC analyses were performed to characterize gene-expression differences. These results were integrated with multigene logistic modeling, decision-curve analysis, and exploratory random forest/SHAP approaches to evaluate molecular interactions and diagnostic relevance. Results: DROSHA, DICER1, and TARBP2 were significantly downregulated in both MDS and AML, suggesting impaired miRNA maturation and a loss of global post-transcriptional control. DGCR8 expression increased across higher-risk MDS groups, suggesting compensatory activation of the Microprocessor complex, whereas AGO1 levels remained relatively stable, consistent with partial maintenance of RISC function. Correlation analyses revealed a co-regulated DROSHA–TARBP2–AGO1 module. ROC, logistic, and machine learning models identified DGCR8 and DICER1 as the strongest diagnostic discriminators. The integrated five-gene signature achieved high discriminative performance (AUC ≈ 0.98) and showed promise but remains preliminary potential for clinical application. Conclusions: Our findings suggest that defects in miRNA biogenesis disrupt hematopoietic homeostasis, reflecting common mechanisms in MDS and AML. The dysregulation of DICER1, DGCR8, and TARBP2 offers insights into miRNA-driven leukemogenesis and may pave the way for miRNA-based diagnostic and therapeutic strategies, pending validation in larger cohorts. Although transcript-level data are provided, future studies should include functional validation to determine the impact on downstream miRNA processing and hematopoietic pathways.
- MakaleAçık Erişim2025Scopus SJRQ2An Integrated In Vitro and In Silico Investigation of the Bioactive Properties of Wild Glycyrrhiza glabra var. glandulifera
Kızıl, Hamit Emre; Ulcay, Sibel; Ekincioğlu, Yavuz; Öğütçü, Hatice; Ağar, Güleray
This investigation examined methanol extracts obtained from the whole plant (encompassing all organs except roots), flowers, and fruits of wild Glycyrrhiza glabra var. glandulifera, a liquorice cultivar indigenous to the Cappadocia region of Türkiye, constituting the first comprehensive in vitro and in silico analysis of this species within the region. Anatomical identification revealed distinctive structural characteristics, including thick-walled epidermal cells in the stem, organized clusters of collenchyma cells, and well-defined sclerenchyma layers encompassing the vascular bundles. The petiole exhibited a characteristic heart-shaped morphology containing three vascular bundles, while foliar analysis demonstrated the presence of stomata on both adaxial and abaxial surfaces, accompanied by a bifacial mesophyll arrangement. The extracts demonstrated remarkable antimicrobial efficacy against both Gram-positive and Gram-negative bacteria, as well as various fungal species. Furthermore, significant cytotoxic activity was observed against non-small cell lung cancer (H460), with the whole plant extract exhibiting IC50 values of 117.8 µg/mL (24 h) and 105.6 µg/mL (48 h). Flower extracts demonstrated IC50 values of 116.8 µg/mL (24 h) and 112.7 µg/mL (48 h), while fruit extracts displayed superior potency with IC50 values of 104.4 µg/mL (24 h) and 63.09 µg/mL (48 h). Molecular docking analyses, conducted utilizing AutoDock Tools 1.5.6 and BIOVIA Discovery Studio Visualizer 4.5, revealed significant protein-ligand interactions, yielding optimal binding energy and inhibition constant values of -9.57 kcal/mol and 96.92 nM, respectively. The RMSD values were calculated based on structural variations between ligand-protein complexes during re-docking procedures. These findings underscore the substantial biological potential of Glycyrrhiza glabra var. glandulifera from Cappadocia, necessitating further comprehensive investigation.
AtıfScopus6WoS6OpenAlex5
İncele - MakaleAçık Erişim2025Scopus SJRQ4Readaptation of the functional reserves of elite mixed martial arts athletes during long-term rehabilitation after musculoskeletal injuries
Savenko, Andrii; Chernozub, Andrii; Turkmen, Mutlu; Olkhovyi, Oleh; Shtefiuk, Ivan; Korchagin, Mukola
Purpose. To study the distinctive characteristics of functional reserve readaptation in elite Mixed Martial Arts (MMA) athletes during long-term rehabilitation after musculoskeletal injuries using various physical therapy protocols. Material & Methods. The study examined 24 elite athletes who sustained musculoskeletal injuries after competitions, predominantly involving the neuromuscular system and limb ligaments. 50 % of the athletes had previously practiced Muay Thai boxing, while the others specialized in Greco-Roman wrestling before MMA. The monitoring of the athletes’ functional reserve readaptation during rehabilitation lasted seven months. The study included four control stages (before injury, and after two, five, and seven months of rehabilitation), each accompanied by a set of test loads designed to evaluate the effectiveness of the readaptation. To assess the adaptive and compensatory responses of the body to the applied loads, a series of blood biomarkers was analyzed, including creatine phosphokinase, lactate dehydrogenase, cortisol, and creatinine. Changes in body composition were tracked using bioimpedance analysis. Results. The most noticeable signs of adaptation failure in elite MMA athletes occurred during the first two months of rehabilitation. Compared to pre-injury data, both groups of athletes showed a decrease in baseline creatine phosphokinase and creatinine levels. This was accompanied by an increase in lactate dehydrogenase activity in their blood serum, marking a significant drop in the body’s functional reserves and overall resistance. During the three-month rehabilitation period, athletes exhibited only partial signs of functional readaptation, despite the implementation of protocols that significantly differed from standard physical therapy approaches. Moreover, a decrease in blood cortisol concentration in response to physical load was detected in both groups, suggesting a low level of resistance and the need for additional energy supply. During the last eight weeks of the seven-month rehabilitation program, exercises replicating 85-90% of MMA technical skills facilitated both the activation and enhancement of functional readaptation. Modifications to the protocols led to an increase in baseline creatinine and creatine phosphokinase levels, along with a decrease in lactate dehydrogenase activity in both groups. Simultaneously, the changes observed in biochemical blood markers in response to the test loads indicated activation of mechanisms supporting short-term adaptation. Conclusions. The findings indicate the limited effectiveness of standard physical therapy protocols in supporting the readaptation of functional reserves among elite MMA athletes during long-term rehabilitation. Despite the high resistance of physiological systems to physical loads recorded before injury, the lack of sufficient muscular activity during the five-month rehabilitation period led to the manifestation of compensatory reactions. Restructuring the rehabilitation protocols with adjusted training loads and exercises simulating 75-80% of combat movements positively influenced the athletes’ recovery. The study results helped to identify and analyze the low effectiveness of functional reserve readaptation observed in many elite MMA athletes during long-term rehabilitation after musculoskeletal injuries.
AtıfOpenAlex3İncele - MakaleAçık Erişim2026Scopus SJRQ1Ecological and nutritional analysis of artificial intelligence-based sustainable dietary models
Köktürk, Seda Nur; Yardımcı, Hülya
Growing concerns over environmental sustainability and health have increased the demand for sustainable diets. Advances in artificial intelligence (AI) offer new opportunities for diet planning. Evaluating the nutritional adequacy and environmental impact of AI-generated sustainable diets is essential. This study aimed to compare the nutritional quality and ecological footprints of sustainable diets created by four popular AI tools (Gemini, Copilot, ChatGPT, and Grok). Each AI tool generated a sustainable diet plan for a healthy adult woman. Diets were evaluated for energy, nutrient content, antioxidant capacity, glycemic index, protein quality, fatty acid profiles, Healthy Eating Index-2015 scores, and ecological footprints. All diets showed low ecological footprints but did not meet energy targets (1800 kcal/day). Gemini had the most sustainable composition. Vitamin B12 was consistently below recommended levels in diets from Gemini, Copilot, and ChatGPT. All diets had adequate carbohydrate, protein, fat quality, and overall diet quality. Carbon footprint associated with protein, energy from protein, cholesterol, pyridoxine, folate, and vitamin C. Water footprint was linked to multiple nutrients, and fruits, meat, poultry, and fish; vegetable intake correlated with carbon footprint. AI-assisted diets have potential for sustainability but nutritional completeness concerns remain, especially for vulnerable groups. Further studies comparing AI and dietitian plans are needed to assess long-term effects.
AtıfScopus1WoS1OpenAlex3İncele - MakaleAçık Erişim2025Scopus SJRQ1Pharmacological Potential and Bioactive Components of Wild Anatolian Sage (Salvia aethiopis L.)
Bilginoğlu, Emine; Kızıl, Hamit Emre; Öğütcü, Hatice; Ağar, Güleray; Bağcı, Yavuz
Salvia aethiopis L., a member of the Lamiaceae family, has gained attention due to its bioactive compounds with potential therapeutic applications. This study investigated the chemical composition and biological activities of S. aethiopis ethanol extract collected from Karaman province, Türkiye. The phenolic profile of the plant was characterized using LC–MS/MS analysis, which revealed substantial amounts of rosmarinic acid, ferulic acid, caffeic acid, and p-coumaric acid. The antimicrobial activity of the extracts was evaluated against various Gram-positive and Gram-negative bacteria, as well as fungal strains, using the agar well diffusion method. The results demonstrated potent antibacterial effects, particularly against Staphylococcus aureus, Micrococcus luteus, and Klebsiella pneumoniae. Furthermore, the cytotoxic potential of S. aethiopis was assessed on H-460 non-small cell lung cancer cells. The extract exhibited a dose-dependent cytotoxic effect, with a significant reduction in cell viability after 24 and 48 h of treatment, yielding IC50 values of 80.08 and 56.19 μg/mL, respectively. These findings suggest that S. aethiopis possesses promising antimicrobial and anticancer properties, which could contribute to the development of novel therapeutic agents.
AtıfScopus8WoS7OpenAlex7İncele - MakaleYalnız künye2026Scopus SJRQ3Acute muscle responses according to training level in traditional Turkish archery: an examination of swelling and damage
Kul, Murat; Hazar, Emre Berk
This study aimed to compare acute muscle swelling and echogenicity responses induced by repeated arrow shooting in experienced and amateur traditional Turkish archers, and to examine the influence of training level using ultrasonography. Twenty-four male athletes (12 experienced, 12 amateur) performed 105 arrow shots. Pre- and post-measurements of upper-extremity muscle thickness (MT) and echogenicity were collected. Data were analyzed using repeated-measures analysis of variance (ANOVA) and paired t-tests. Both groups showed significant increases in MT, particularly in experienced archers. Echogenicity increased in several muscles, notably the supraspinatus, brachialis, pronator teres, and brachioradialis. The lack of strong correlation between MT and echogenicity suggests that these parameters reflect distinct acute muscular responses. In conclusion, training level influences acute muscular adaptations to shooting, and certain muscles may require targeted protection to prevent overuse injuries. This study provides the first ultrasonographic evaluation of these responses in traditional Turkish archery.
- MakaleYalnız künye2026Scopus SJRQ2Investigation of magnetic levitation performance in Ag-added DyBa2Cu3O7-δ superconductors fabricated by single-direction melt growth (SDMG) method
Doğruer, M.; Abdioğlu, M.; Motoki, T.; Ozturk, U. Kemal
Abstract This study investigates the magnetic levitation and guidance characteristics of Ag-doped DyBa2Cu3O7-δ superconducting bulks, synthesized by the single-direction melt growth (SDMG) technique. The levitation force, vertical stiffness and lateral guidance force are measured at varying cooling heights (CHs) of 5 mm, 25 mm and 50 mm, with a constant working height (WH) of 5 mm for lateral force measurements. DyBa2Cu3O7-δ samples are cooled using liquid nitrogen (77 K) and thermal stabilization is achieved before force data collection. Results show that levitation forces increase with CH, while the levitation force curves exhibit both attractive and repulsive behavior depending on the CH. The lateral guidance force is higher for the Ag2 sample than for the Ag1 sample and decreased as the temperature decreased. Vertical stiffness also increased with CH and decreased as the levitation gap decreased, confirming heightened guidance forces at smaller distances. The flux density distributions, including both lateral ( B x ) and vertical ( B y ) components, are found to significantly impact the levitation and guidance force performance. Specifically, configurations with concentrated B x gradients improved levitation stability, while configurations with distributed B y led to stronger guidance forces. These findings underscore the importance of optimizing the PMG design to balance B x for levitation and B y for guidance in superconducting systems.
- MakaleAçık Erişim2025Scopus SJRQ1Investigation of endocrine and cerebral response and nutrition and physical performance parameters according to bigorexia nervosa levels: a cross-sectional study in sports sciences faculty students
Erkılıç, Ali Ozan; Bayraktar, Bülent; Erkiliç, Tuğçe Orkun; Türkmen, Mutlu; Kul, Murat; Yönal, Mehmet
The aim of this study is to investigate the effects of Bigorexia nervosa (BGN) levels on endocrine (Asprosin, GLP-1) and cerebral (BDNF) responses and nutritional and physical (6MWT, Six-Minute Walk Test)), speed, metabolic equivalent unit (MET)) performance parameters in students of the faculty of sports sciences. This study investigated muscle dysmorphic disorder (MDD), physical activity levels, and specific hormonal markers in 120 university students (63 females, 57 males) aged 18–25 years, all studying sport sciences and reporting no existing health problems. Participants completed a demographic questionnaire, food frequency questionnaire and the Muscle Dysmorphic Disorder (Bigorexia) Inventory through face-to-face interviews. Physical activity was assessed using the 6-Minute Walk Test (6MWT) to measure walking distance, and Metabolic Equivalent (MET) was calculated based on the American College of Sports Medicine (ACSM) formula. Body Mass Index (BMI) was determined from anthropometric measurements of height and body weight. Saliva samples were collected to analyze Asprosin, BDNF, and GLP-1 hormone levels using the ELISA technique.Data were analyzed using number, percentage, mean, chi-square, t-test, Pearson correlation, and ANOVA tests. In all analyses, significance was accepted as p < 0.05. According to the demographic findings of the study, the majority of participants (64.2%) were third-year students, and 52.5% were female. The mean age of the participants was 22.01 years, the mean height was 168.59 cm, and the mean weight was 62.61 kg. 73.3% of the individuals were classified as normal weight, 12.5% as pre-obese, 11.7% as underweight, and 2.5% as obese. Men had significantly higher bigorexia and its subscale scores than women (p < 0.05), and bigorexia was positively correlated with height and negatively correlated with BMI (p < 0.01). Mean salivary BDNF levels were higher in participants consuming 1–2 meals per day (p = 0.035), and mean salivary asprosin levels were significantly higher in the obese group compared to the healthy group (p = 0.008). Additionally, a strong positive correlation was found between asprosin and GLP1 levels (r = 0.585; p < 0.01). Bigorexia status was significantly associated with meat, meat products, and fat consumption (p < 0.05), while no association was found with physical performance parameters such as 6MWT, speed, and MET (p > 0.05). The average MET value was found to be 4.53, indicating that participants generally engaged in moderate-intensity physical activity. In conclusion, examining endocrine (asprosin, GLP-1) and cerebral (BDNF) hormone responses, as well as nutritional and physical performance parameters, according to BGN levels reveals the impact of BGN on physiological and nutritional behaviors. Given the impact of BGN trends on students’ health, examining hormone profiles and their relationships with physical performance and nutrition is believed to significantly contribute to understanding the health problems associated with BGN and developing appropriate interventions.
- MakaleAçık Erişim2025Scopus SJRQ2Microstructure and Mechanical Properties Change of Al7SiMgxEr (x: 0.03–0.1)
Colak, Murat; Muhammed, Enes Aydin; Turkmen, Mustafa; Dispinar, Derya
Aluminum and its alloys are widely used in many fields, such as automotive, aerospace, and defense industries, due to their many advantages. Due to such critical applications, the quality demands are also increasing. With the recent development in technologies, studies on casting of aluminum with different alloying element additions are ongoing rapidly. Various elements are added to the alloy to provide the desired properties. In this study, the effects of 0.03, 0.06, and 0.1 wt% Er addition to A356 aluminum alloy were evaluated simply because in the literature, only 0.1 wt% and above additions were studied. Samples were prepared using permanent molds and subjected to mechanical testing and microstructural characterization. Changes in the microstructure (evaluated via SDAS and SDAL) and mechanical properties of the cast specimens were analyzed. The results showed that Er addition improved tensile strength by up to 30%, increased elongation fourfold, and enhanced toughness by a factor of 4.5.
- DüzeltmeAçık Erişim2026Scopus SJRQ1Correction to: Exploring the transformative power of GenAI in education: an exploratory journey from social studies classes (Education and Information Technologies, (2025), 10.1007/s10639-025-13814-z)
Yetişensoy, Okan
The original online version of this article has been corrected. Figure 3 is removed upon the author’s request.
- MakaleAçık Erişim2025Scopus SJRQ1A Hybrid Retrieval Method for an Ω-Class Bianisotropic Metamaterial Using Scattering Parameter Method
Ozturk, Gokhan; Hasar, Ugur Cem; Kaya, Yunus; Korkmaz, Huseyin; Stoyanov, Ivaylo
In this study, a hybrid retrieval method is proposed to retrieve all terms in the electric and magnetic tensors (along with coupling tensors) of Ω -class bianisotropic metamaterial (MM) slabs using scattering (S-) parameters of both normal incidence TE2 mode and oblique incidence TM2 and TE modes. Compared with other extraction methods in the literature, our retrieval method fully characterizes the MM slab (extracts all constitutive parameters) without necessitating any numerical technique (non-iterative) using fewer wave configurations (two modes) and sample configurations (one configuration). Contrary to two sample configurations required in the application of previous retrieval methods in the literature, one sample configuration (with and without its rotation in the transverse plane) significantly decreases the effect of fabrication tolerances on the accuracy of extraction. The proposed extraction method is first validated by a bulk MM slab synthesized by the Lorentz and Drude models. Then, it is applied for extracting the electromagnetic properties of two bianisotropic MM slabs in the form of square split-ring-resonators and Ω -shape using their S-parameters simulated by a full wave simulation program. Finally, its accuracy is examined by comparing simulated S-parameters with those reconstructed by using extracted electromagnetic parameters. It is observed that our proposed method determines the constitutive parameters with a relatively higher accuracy in a relatively short amount of time.
AtıfScopus2WoS1İncele - MakaleYalnız künye2026Scopus SJRQ1Associations between preschool children’s perspective-taking skills and their perceived abilities and behavioral intentions toward peers with special educational needs
Ari-Arat, Ceren; Tutkun, Cansu
The aim of this study was to examine the associations between preschool children’s perceived capabilities, perspective-taking skills, and behavioral intentions toward peers with special educational needs. The sample consisted of 193 preschool children aged 4 to 6 years, selected through convenience sampling from early childhood education centres in Bayburt, Türkiye. A quantitative cross-sectional design was employed. Data were collected using the Child Information Form, the Perceived Capabilities Scale, the Behavioral Intentions Scale, and the Child Perspective-Taking Test. Data collection was conducted in one-on-one sessions over two meetings per child, with an average duration of 18 min. Small but statistically significant positive associations were observed between children’s perceived capabilities and their behavioral intentions across the three peer conditions (r =.283-0.289, p <.01). Small associations were also observed between selected perspective-taking components and behavioral intentions in the bivariate analyses; however, none of the perspective-taking components remained significantly associated with behavioral intentions after the other variables were taken into account. Across the three regression models, perceived capabilities were the only variable that remained significantly associated with behavioral intentions (β = 0.268-0.289, p <.001). The regression models explained a modest proportion of the variance in behavioral intentions (R² = 0.093-0.106; adjusted R² = 0.074-0.087). Exploratory group comparisons indicated selective differences in perspective-taking according to reported experience with peers with SEN; however, these findings should be interpreted cautiously because experience was measured dichotomously and the direct-experience groups were highly unequal. Girls reported slightly higher behavioral intentions toward peers with physical disabilities than boys (t = 2.318, p =.022), whereas no significant age-related differences were observed.
- MakaleYalnız künye2025Scopus SJRQ2HERMITE–HADAMARD TYPE INTEGRAL INEQUALITIES FOR SEMIHARMONICALLY P-FUNCTIONS
Kadakal, Mahir; Iscan, İMDAT; Kadakal, Huriye
The authors introduce the concept of semiharmonically P-functions and establish some Hermite–Hadamard type integral inequalities for these classes of functions. Also, the authors compare the results obtained Hölder and Hölder–˙ I¸scan inequalities and show that the result obtained with Hölder–˙ I¸scan inequalities give better approach than the others. Some applications to special means of real numbers are also given.
- MakaleAçık Erişim2026Scopus SJRQ3Are Geopolitical Risks a Permanent Driver of Global Inflation? Evidence from 1985-2024
Yıldız, Ümit
This study investigates the causal relationship between geopolitical risks and global inflation and examines whether this causal effect, if any, is persistent. To this end, the stationarity of the annual Geopolitical Risk Index (GPR) and global inflation series for the 1985–2024 period was first analyzed using the Lee and Strazicich (2003) two-break unit root test, which concluded that the series are stationary at levels. Subsequently, the data were analyzed using a stationary frequency domain causality approach, revealing a unidirectional causal relationship running from GPR to global inflation at both low and high frequencies. The causality identified at low frequencies indicates that this causal effect is permanent. The findings of the study suggest that mitigating geopolitical risks is of vital importance in the fight against global inflation.
- MakaleYayıncıda açık erişim2026Scopus SJRQ2Metabolic, adipokine (irisin, spexin, visfatin), and ER stress (GRP78) responses in multiparous Brown Swiss cows: a multivariate approach across physiological stages and body condition scores
Kotan, Gökşad Cemil; Aydemir, Şeyma; Bayraktar, Bülent
This study investigated the responses of novel adipokines (irisin, spexin, visfatin), an endoplasmic reticulum (ER) stress marker (GRP78), and traditional metabolic parameters (non-esterified fatty acids (NEFAs), beta-hydroxybutyrate (BHBA), urea, albumin, globulin, total cholesterol) in 360 healthy Brown Swiss dairy cattle. The animals were categorized into 18 subgroups based on pregnancy stages (early, mid, dry), lactation stages (early, mid, late), and body condition scores (BCSs). Serum analyses were performed using ELISA and spectrophotometric methods. Interactions between physiological stages and BCS were highly significant for all measured parameters (p<0.001). Results showed that mean serum levels of spexin (ranging from 14.02 to 36.04 pg mL−1) and irisin increased as pregnancy and lactation progressed. Visfatin levels exhibited a significant increase specifically during the gestation period, peaking during the dry period (24.09 ng mL−1), and maintained a significant increasing trend as lactation progressed toward the late stage (Tables 2, 4). Conversely, GRP78 (peaking at 0.46 ng mL−1), NEFA (peaking at 0.52 mmol L−1), and urea levels peaked during the dry period and early lactation, subsequently decreasing as metabolic stability was achieved. Notably, during the dry period, stress markers rose despite declining albumin and globulin levels (p<0.05). These data indicate that the dry period and early lactation are the most critical phases for metabolic and cellular stress, characterized by lower spexin and elevated GRP78 and NEFA concentrations. The later rise in irisin and visfatin, while BHBA remained within physiological limits, confirms successful metabolic adaptation (p<0.001). In conclusion, the integrated evaluation of these novel biomarkers is anticipated to provide significant contributions to protective strategies and metabolic management in dairy cattle.
- MakaleYalnız künye2026Scopus SJRQ1Effect of ultra-processed food consumption on premenstrual syndrome across different body mass index categories: a cross-sectional analysis
Köktürk, Seda Nur; Taş Yıldırım, Esra; Yardımcı, Hülya
Purpose – This study aimed to examine the association between ultra-processed food (UPF) consumption and premenstrual syndrome (PMS) across different body mass index (BMI) categories in women. Design/methodology/approach – A total of 480 women aged 20–49 years participated in the study between May 2024 and May 2025 in 3 cities in Türkiye. PMS symptoms were assessed using the Premenstrual Syndrome Scale (PMSS), and UPF intake was evaluated according to the NOVA classification using a food frequency questionnaire. Anthropometric measurements, including height and body weight, were taken by researchers, and BMI was calculated for each participant. Findings – The mean BMI of the participants was 24.2 ± 4.9 kg/m2, with an average daily UPF intake of 858.0 ± 133.3 g. Higher UPF intake was significantly associated with increased reporting of PMS, with 7.0% higher odds among normal-weight women, 19.0% higher odds among overweight women, and 41.0% higher odds among women with obesity. Moreover, as UPF consumption increased from the lowest (Q1) to the highest quartile (Q4), the odds of experiencing PMS symptoms were 2.65 times (OR: 2.65, %95 CI: 1.52–4.61), 2.85 times (OR: 2.85, %95 CI:1.60–4.95), and 3.07 times (OR: 3.07, %95 CI: 1.71–5.49) higher, respectively (p = 0.001). Research limitations/implications – These findings underscore a significant association between UPF consumption and PMS symptoms, particularly among women with obesity. Given the high prevalence of PMS and its substantial impact on women's well-being, dietary interventions aimed at reducing UPF intake may represent a promising approach for PMS management and prevention. Originality/value – To the best of our knowledge, this study is the first to examine the relationship between UPF intake and self-reported PMS presence across different BMI categories. 2026
