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Gastrointestinal stability and bioactivity of propolis from diverse origins

MakaleAçık ErişimScopus SJRQ1

Özet

Propolis is a chemically complex bee product whose biological properties depend on its botanical and geographical origin. However, little is known about how gastrointestinal digestion affects its phenolic profile and bioactivity. In this study, twelve propolis samples from eight countries were evaluated for phenolic and flavonoid contents, antioxidant capacity (FRAP, ABTS+•), and urease inhibition before and after simulated gastric digestion. RP-HPLC–PDA identified 26 phenolic compounds showing substantial compositional diversity. Turkish Bolu propolis retained the highest post-gastric FRAP value, while several samples (BBP, AFP) maintained or enhanced urease inhibition. PCA and HCA highlighted origin-dependent differentiation, identifying digestive stability as a key variable for functional potential.

Anahtar Kelimeler

Antioxidant activityGastrointestinal stabilityHCAPCAPropolisUrease inhibition
RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/bayburt/12772Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.1007/s00217-026-05104-wYayıncı resmi DOI adresi
İndeks kayıtları
ScopusScopusWeb of ScienceWeb of Science
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Atıflar
Scopus
0
WoS
0
OpenAlex
2
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Tam Kayıt
AlanDeğerDil
dc.contributor.authorCan, Zehra
dc.contributor.authorÇelebi, Zeynep Berin
dc.contributor.authorTunca, Erol
dc.contributor.authorKolaylı, Sevgi
dc.contributor.authorSevin, Sedat
dc.contributor.authorTutun, Hidayet
dc.date.accessioned2026-10-29T19:10:00.568672651Z
dc.date.available2026-10-29T19:10:00.568672651Z
dc.date.issued2026
dc.description.abstractPropolis is a chemically complex bee product whose biological properties depend on its botanical and geographical origin. However, little is known about how gastrointestinal digestion affects its phenolic profile and bioactivity. In this study, twelve propolis samples from eight countries were evaluated for phenolic and flavonoid contents, antioxidant capacity (FRAP, ABTS+•), and urease inhibition before and after simulated gastric digestion. RP-HPLC–PDA identified 26 phenolic compounds showing substantial compositional diversity. Turkish Bolu propolis retained the highest post-gastric FRAP value, while several samples (BBP, AFP) maintained or enhanced urease inhibition. PCA and HCA highlighted origin-dependent differentiation, identifying digestive stability as a key variable for functional potential.
dc.description.sponsorshipTürkiye Bilimsel ve Teknolojik Araştırma Kurumu, TUBITAK
dc.identifier.articlenumber175
dc.identifier.doi10.1007/s00217-026-05104-w
dc.identifier.eissn1438-2385
dc.identifier.issn1438-2377
dc.identifier.issue4
dc.identifier.scopus2-s2.0-105033442667
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/bayburt/12772
dc.identifier.volume252
dc.identifier.wosWOS:001717804200001
dc.language.isoen
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.relation.ispartofEuropean Food Research and Technology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntioxidant activity
dc.subjectGastrointestinal stability
dc.subjectHCA
dc.subjectPCA
dc.subjectPropolis
dc.subjectUrease inhibition
dc.subject.classificationFood Science & Technology
dc.subject.otherBioactivity
dc.subject.otherAntioxidant activities
dc.subject.otherBiological properties
dc.subject.otherGastrointestinal
dc.subject.otherGastrointestinal digestion
dc.subject.otherGastrointestinal stability
dc.subject.otherGeographical origins
dc.subject.otherHCA
dc.subject.otherPCA
dc.subject.otherPropolis
dc.subject.otherUrease inhibitions
dc.subject.otherAntioxidants
dc.titleGastrointestinal stability and bioactivity of propolis from diverse origins
dc.typeArticle
rdl.citation.openalex2
rdl.citation.scopus0
rdl.citation.wos0
rdl.oa.statushybrid
rdl.oa.urlhttps://link.springer.com/content/pdf/10.1007/s00217-026-05104-w.pdf
rdl.scopus.quartileQ1
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.wos.indexScience Citation Index Expanded (SCI-EXPANDED)