Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Kutlu, Naciye(4)
- Kamiloğlu, Aybike(2)
- Abca, Tuğba Elbir(1)
- Bayram, Nesrin Ecem(1)
- Bayram, Sinan(1)
- Can Gerçek, Yusuf(1)
- Ecem-Bayram, Nesrin(1)
- Elbir Abca, Tuğba(1)
- Gercek, Ynsuf Can(1)
- Goksen, Gulden(1)
- Gıdık, Betül(1)
- Kumar, Manoj(1)
- Lorenzo, José Manuel(1)
- Walayat, Noman(1)
- Yilmaz, Özlem(1)
- Yurdunuseven-Yıldız, Aysun(1)
- Yüzer, Elvan(1)
- Yüzer, Mustafa Onur(1)
- Yılmaz, Özlem(1)
- Çelik, Saffet(1)
- Öztekin, Sebahat(1)
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ1Optimization of Hemp Seed (Cannabis sativa L.) Protein Extraction and Glycation Conditions by Response Surface Methodology: Physicochemical, Functional, and Thermal Characteristics
Yüzer, Elvan; Kutlu, Naciye; Yüzer, Mustafa Onur
In this study, first, optimization using the response surface method was implemented to obtain the highest yield of protein isolate from defatted hemp seed under different extraction conditions. Optimum extraction conditions were determined with 0% salt concentration, 12 pH value, and 49°C temperature. The protein isolate produced under optimum conditions was subjected to the glycation process, and the glycation conditions were also optimized. The optimum conditions for glycation were determined as a protein isolate: sugar ratio of 1.6:1, temperature of 60°C, and time of 90 min, providing the most suitable glycation degrees and browning indices. There was no statistical difference between the glycated protein isolate obtained under these conditions and the nonglycated protein isolate in terms of emulsifying activity index and emulsion stability index. For total phenolic–flavonoid compounds and antioxidant activity, the sugar complex caused a decrease in these values. In addition, there was a high positive correlation between bioactive compounds. SEM micrographs showed relationships between hemp seed protein isolate and sugar, and these interactions led to a spongy three-dimensional microstructure. When the FTIR results were analyzed, the glycated isolate had stronger absorption at 3300–3200 cm−1 compared to the nonglycated isolate. In conclusion, this study reports important findings in terms of functional and characteristic properties of how monosaccharides affect glycation.
AtıfScopus1WoS1
İncele - MakaleYalnız künye2025Scopus SJRQ1Extraction of Bioactive Compounds from Celery Root Peels Using an Ultrasound-Assisted Method with Choline Chloride–Based Deep Eutectic Solvents
Kamiloğlu, Aybike; Kutlu, Naciye; Elbir Abca, Tuğba; Yılmaz, Özlem
The concepts of sustainable and green technology have come to the forefront due to problems such as increasing environmental pollution, depletion of resources, and uncontrolled increases in industrialization. Green chemistry aims to reduce or completely eliminate pollution in the environment. In this study, both the ultrasonic method, which is a form of green technology, and deep eutectic solvents, which are among green solvents, were used, and a perspective on creating economic value from a waste product (celery root peel) is presented. In this context, phytochemical compounds (total flavonoid content and antioxidant activities) were obtained from celery root peels by ultrasonic-assisted extraction using 10 different choline chloride–based deep eutectic solvents, and the results were compared with methanol, an organic solvent. As a result, according to the total flavonoid content, the most effective deep eutectic solvent was choline chloride to sucrose, while according to the antioxidant activity value, choline chloride to lactic acid was found to be effective. For all of the analyzed bioactive compounds, higher or equal yields were obtained with all deep eutectic solvent extracts compared to methanol, and deep eutectic solvents could be alternatives to organic solvents (such as methanol) that may have toxic effects on humans or the environment.
AtıfScopus9WoS9OpenAlex10İncele - MakaleAçık Erişim2024Scopus SJRQ1Ultrasound-assisted deep eutectic solvent extraction of bioactive compounds from persimmon calyx
Kutlu, Naciye; Kamiloğlu, Aybike; Abca, Tuğba Elbir; Yilmaz, Özlem
Abstract: This study aimed to investigate the ultrasound-assisted extraction of bioactive compounds from persimmon (Diospyros kaki) calyx by deep eutectic solvents (DES) with different molar ratios. For this reason, the prepared DES extracts’ total phenolic–flavonoid compounds and antioxidant activities (1,1-diphenyl-2-picrilhydrazyl radical scavenging activity [DPPH•], Cupric Reducing Antioxidant Capacity (CUPRAC), and ferric reducing antioxidant power [FRAP]) were investigated as a result of the experimental design and optimization study conducted for this purpose. A sonication time of 20 min was determined as the optimal condition. Under these conditions, a molar ratio of 1.9:1 (lactic acid:choline chloride) and a water ratio of 70% provided the highest phenolic/flavonoid compounds and antioxidative activity. Correlations among water ratio, molar ratio, and sonication time were determined using principal component analysis (PCA). In conditions where total flavonoid compound, FRAP, and DPPH• are high due to PCA, it can be concluded that the sonication time is at high level; on the contrary, the water and molar ratios are at low level. In conclusion, ultrasound-assisted extraction using DES proved effective in persimmon calyx. Therefore, it can be recommended to use these environmentally friendly green solvents as an alternative to organic solvents in preparing extracts in various fields. Practical Application: This study shows the effectiveness of the ultrasound-assisted green extraction method using persimmon calyx specified as waste. These findings are compelling in the food industry in terms of consumers being now aware of green technology and the discovery that calyx is a good source of bioactive compounds.
AtıfScopus19WoS21OpenAlex23
İncele - Derleme MakaleAçık Erişim2024Scopus SJRQ1Oxidative stability, quality, and bioactive compounds of oils obtained by ultrasound and microwave-assisted oil extraction
Walayat, Noman; Yurdunuseven-Yıldız, Aysun; Kumar, Manoj; Goksen, Gulden; Öztekin, Sebahat; Lorenzo, José Manuel
Vegetable oils are extracted from oilseeds, fruits and other parts of plants. The method used in oil extraction is of great importance, as it affects both the quality of the final product and the environment. It is desirable that the extraction method be minimally costly, fast, environmentally friendly, and produce oil of high quality and quantity. Common oil extraction methods are mechanical pressing and solvent extraction, and these methods have advantages and disadvantages over each other. Mechanical extraction and solvent extraction are controversial due to poor product quality and high environmental impacts. This review presents applications where conventional oil extraction processes are assisted by microwave or ultrasound. It is necessary to evaluate the impact of ultrasound and microwave-assisted extraction on the quality of the extracted oil and also to compare the results with those of conventional extraction methods. For this purpose, this review discusses the effects of microwave and ultrasound-assisted extraction on the physicochemical, oxidation indices, bioactive compounds, and antioxidant properties of oil extracted from oil seeds and fruits. Furthermore, this review provides readers with in-depth information on the mechanisms involved, their use, and the impact of operating conditions. The yield and quality of the oil obtained by these processes can vary depending on parameters such as microwave power, ultrasound power, processing time, and temperature. Finally, the review also discusses the challenges and advantages of the industrial application of these technologies.
AtıfScopus47WoS41OpenAlex45İncele - MakaleAçık Erişim2023Scopus SJRQ2Extraction of Functional Compounds from Tarragon (Artemisia dracunculus L.) by Deep Eutectic Solvents at Different Properties
Can Gerçek, Yusuf; Kutlu, Naciye; Çelik, Saffet; Gıdık, Betül; Bayram, Sinan; Bayram, Nesrin Ecem
In this study, it was aimed to examine the capacity of deep eutectic solvents (DESs) with different contents to extract bioactive compounds from tarragon (Artemisia dracunculus L.) plant. For this reason, the total phenolic-flavonoid content, total proanthocyanidin content and antioxidant/antimicrobial activities of the prepared DES extracts were investigated, as well as the individual phenolic and individual amino acid profiles. According to the results, DES10 had the highest efficiency in terms of its capacity to extract individual phenolics (approximately 59 mg/100 g) and individual amino acids (approximately 2500 mg/kg), and also gave a higher yield compared to ethanol (approximately 44 mg/100 g for individual phenolics and about 19810 mg/kg for individual amino acids) and methanol (approximately 58 mg/100 g for individual phenolics and approximately 21430 mg/kg for individual amino acids). However, the total phenolic content, total flavonoid content and antioxidant activity values of DES extracts were determined between 59.09–77.50 mg GAE/100 g, 28.68–45.55 mg GAE/100 g and 42.96–146.86 mg TE/100 g, respectively. Therefore, it can be recommended to use these green solvents, which are known as environmentally friendly, as an alternative to organic solvents in the process of preparing extracts of this important medicinal plant in different areas.
AtıfScopus8WoS6OpenAlex9İncele - MakaleYalnız künye2019Scopus SJRQ4Appropriate maceration duration for the extraction of propolis
Ecem-Bayram, Nesrin; Gercek, Ynsuf Can
The importance of the use of natural products as nutritional supplements in order to increase the quality of life and prevent diseases has increased in recent years. Among these products, propolis produced by honey bees is collected from plants and has a very complex structure in terms of chemical content. Propolis and its extracts have been used by humans for centuries because of its various bioactive properties. Although different methods can be used in the extraction stage, the most commonly used technique is extraction by maceration. However, there is no standard time period for extraction of propolis by maceration. We aimed to determine the changes in the concentrations of flavonoid group compounds pinocembrin, chrysin, tectochrysin, pi-nostrobin chalcone, gengwanin, naringenin and galangin from propolis samples exposed to seven different periods (1, 2, 5 10, 15, 20, 30 days) of maceration using GC-MS. The flavonoids pinocembrin, chrysin, tectochrysin, and naringenin reached their maximum concentrations at the end of 15 days of maceration and a decrease in their concentrations was observed after this period. The concentrations of other flavonoids did not show a steady increase or decrease with different maceration times. As a result, it can be said that the appropriate duration of maceration to extract the flavonoids responsible for propolis' numerous activities varies depending on the origin of the propolis and the nature of the compounds to be extracted.
AtıfScopus9İncele