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- MakaleAçık Erişim2026Scopus SJRQ2Perceived burdensomeness and happiness in cohabiting older adults: The serial mediating roles of mental well-being and loneliness
Akeren, Zahide; Akeren, Ihsan; Kalyoncuo, Servet
Background Aging-related changes and increased dependence on family members may negatively affect older adults’ psychological well-being. Perceived burdensomeness refers to the belief that one is a burden on others and has been associated with lower happiness, reduced mental well-being, and greater loneliness. Among adults living with their families, mental well-being and loneliness may explain how perceived burdensomeness relates to happiness in later life. Purpose This study examined the associations between perceived burdensomeness and happiness among older adults living with their families and evaluated the serial mediating roles of mental well-being and loneliness. Methods This cross-sectional study included individuals aged ≥65 years residing with family members in a city in Turkey’s Eastern Black Sea region. Data were collected from 273 older adults; after preliminary screening, 7 cases were excluded, resulting in a final analytic sample of N = 266. Measures included the Geriatric Feelings of Burdensomeness Scale, WHO-5, the Happiness Scale, and the Loneliness Scale for the Elderly. Serial mediation was tested using a regression-based approach with bootstrap confidence intervals. Results Perceived burdensomeness was associated with lower mental well-being and higher loneliness. The total association between burdensomeness and happiness was negative (β=-0.467), and more than two-thirds of this association operated indirectly through mental well-being and loneliness. Conclusion and Implications Perceived burdensomeness was associated with lower happiness among older adults living with their families, primarily through reduced mental well-being and increased loneliness. In geriatric nursing and primary care, routinely assessing these psychosocial factors and implementing family-centered and social support-oriented interventions may help improve happiness.
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İncele - MakaleAçık Erişim2026Scopus SJRQ2Modulation of stress and neuroplasticity biomarkers via rhythmic vocalization: a controlled study on NDNF, cortisol, and monoamines
Okur, Süheyb; Bayraktar, Bülent
Background: The aim of this study is to investigate the effect of reciting the Quran (from Mushaf) on serotonin, dopamine, NDNF, and cortisol levels in relation to mental well-being. Methods: This study was conducted on a sample of university students who know how to read the Quran in Türkiye, selected by a non-probability method, with a pre-test-post-test control group and a longitudinal design; the assignment to the groups was also done randomly. The research was carried out with 72 university students (36 female, 36 male), aged 19–30, who know how to read the Quran and do not have any health problems. Two groups were formed: a 36-person experimental group and a 36-person passive resting control group. The Mental Well-Being Scale and a personal information form were used to evaluate the participants’ well-being status. Salivary serotonin, dopamine, NDNF, and cortisol levels were examined using the ELISA technique in samples taken before and after the experimental group recited verses 195–200 of Surah Al-i Imran aloud. Number, percentage, mean, Pearson correlation, and ANOVA tests were used to evaluate the data. Statistical significance was accepted as p <.05 for all analyses. Results: A significant group-time interaction was found (p <.05). Compared to the passive resting control group, the experimental group showed statistically significant increases in salivary serotonin, dopamine, and NDNF levels, and a significant decrease in cortisol levels. However, a critical dissociation was observed: despite this neuroprotective biomarker profile, the control group reported statistically significantly higher post-intervention mental well-being scores than the experimental group (p <.05). This suggests that the acute cognitive load and performance anxiety associated with the recitation task may temporarily mask physiological benefits in self-reports. Conclusions: A brief (5-minute) ‘Tartil’ recitation of the Quran demonstrates immediate, positive neurobiological effects by reducing stress hormones (cortisol) and increasing reward- and neuroplasticity-related biomarkers (dopamine, serotonin, NDNF). However, this did not immediately translate to higher self-reported well-being, suggesting the relationship between the neurobiology of recitation and its perceived psychological effects is complex and potentially confounded by factors such as performance anxiety or cognitive load in an experimental setting. Clinical trial number: Not applicable.
AtıfScopus2WoS3OpenAlex4İncele - MakaleYalnız künye2025Investigation of fatigue, mental well-being and tachycardia in short- and long-term metformin use
Akeren, Zahide
Purpose: The current study aimed compare short and long-term metformin users according to sociodemographic characteristics and to examine the relationships between fatigue, tachycardia and psychological well-being. Materials and Methods: In cross-sectional study were reached 92 patients, 46 short-term and 46 long-term metformin users. It was measured fatigue with the Functional Assessment of Chronic Illness Treatment Fatigue Scale (FACIT-F), tachycardia with saturation device, well-being with the World Health Organization Well-Being Index (WHO-5). Results: For the group using short-term metformin, the mean; year of metformin use was 1.82 +/- 0.77 and pulse rate was 82.48 +/- 8.80, FACIT-F score was 20.37 +/- 7.25, and WHO-5 score was 15.70 +/- 3.23. The group using long-term metformin mean year of metformin use was 5.93 +/- 2.68, pulse rate was 84.57 +/- 9.64, FACIT-F score was 25.33 +/- 5.65 and WHO-5 score was 12.63 +/- 3.70. Well-being negatively correlated with the year of diabetes, year of metformin use, pulse rate and fatigue. FACIT-F, metformin year and pulse rate explain a total of 41.9% of the variance in well-being. FACIT-F ((3=-.51, t=-5.82, p= .000) and the year of metformin use ((3=-.19, t=-2.12, p= .037) significantly decrease well-being, while pulse rate does not have a significant effect on well-being. Conclusions: Long-term use of metformin has been found cause fatigue and negative psychological well-being. Fatigue, year of metformin use and pulse rate number are important predictors of psychological well-being in Type II diabetes patients using metformin.
- MakaleAçık Erişim2025Scopus SJRQ1Understanding the moderating role of gender in physical activity enjoyment and mental well-being: evidence from university students’ campus recreation participation
Karakullukcu, Omur Fatih; Ayhan, Cihan; Guder, Ferhat; Talaghir, Laurentiu-Gabriel; Cosoreanu, Dumitru Marius; Bentea, Cristina Corina
Background: Participation in physical activity is considered an important factor not only for individuals’ physical health but also for their psychological well-being. Developing physical activity habits, especially among university-aged individuals, plays a critical role in long-term health outcomes. In this context, the impact of physical activity enjoyment on individuals’ mental well-being has become a topic of interest. However, the moderating role of individual differences, particularly gender, in this relationship has not yet been sufficiently clarified. The purpose of this study was to examine the relationship between physical activity enjoyment and mental well-being among university students and to reveal the moderating effect of gender on this relationship. Method: The research was conducted using a relational screening model. The study group consisted of 392 university students (261 male and 131 female; mean age = 22.95 ± 2.58) from Sakarya University of Applied Sciences who participated in campus recreation activities. Data were collected via a face-to-face survey using the Physical Activity Enjoyment Scale and the Mental Well-being Scale. Descriptive statistics, Pearson correlation analysis, and regression-based moderation analysis using PROCESS Macro Model 1 were used in the statistical analysis. Results: The level of enjoyment of physical activity was found to have a significant positive effect on mental well-being (r = 0.427, p = 0.001; F = 50.388, p < 0.001; R2 = 0.280). Moderation analysis further showed that gender significantly moderated this relationship (ΔR2 = 0.049; p < 0.001). The effect of enjoyment on mental well-being was significant for both males (β = 0.2693; S.E. = 0.0348; p < 0.001; 95% CI [0.2010, 0.3377]) and females (β = 0.7913; S.E. = 0.0949; p < 0.001; 95% CI [0.6047, 0.9780]), with the effect being stronger among females. Conclusion: The findings show that considering gender-sensitive approaches in physical activity programs to be implemented on university campuses has a potential impact on improving the psychological well-being of students.
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