Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2023Scopus SJRQ3
    The effect of heart failure on gut microbial richness and diversity; [O efeito da insuficiência cardíaca estável na riqueza e diversidade microbiana intestinal]

    Kilic, Oguz; Kaya, Halil Ibrahim; Secme, Mucahit; Kilinc, Mehmet; Sevgican, Cihan Ilyas; Buber, Ipek; Dodurga, Yavuz; Simsek, Omer; Ergin, Cagrı; Kilic, Ismail Dogu

    Introduction and objective: With recent advances in genome sequencing technology, a large body of evidence has accumulated over the last few years linking alterations in microbiota with cardiovascular disease. In this study, we aimed to compare gut microbial composition using 16S ribosomal DNA (rDNA) sequencing techniques in patients with coronary artery disease (CAD) and stable heart failure (HF) with reduced ejection fraction and patients with CAD but with normal ejection fraction. We also studied the relationship between systemic inflammatory markers and microbial richness and diversity. Methods: A total of 40 patients (19 with HF and CAD, 21 with CAD but without HF) were included in the study. HF was defined as left ventricular ejection fraction <40%. Only stable ambulatory patients were included in the study. Gut microbiota were assessed from the participants’ fecal samples. The diversity and richness of microbial populations in each sample were assessed by the Chao1-estimated OTU number and the Shannon index. Results: The Chao1-estimated OTU number and Shannon index were similar between HF and control groups. There was no statistically significant relationship between inflammatory marker levels (tumor necrosis factor-alpha, interleukin 1-beta, endotoxin, C-reactive protein, galectin-3, interleukin 6, and lipopolysaccharide-binding protein) and microbial richness and diversity when analyzed at the phylum level. Conclusion: In the current study, compared to patients with CAD but without HF, stable HF patients with CAD did not show changes in gut microbial richness and diversity. At the genus level Enterococcus sp. was more commonly identified in HF patients, in addition to certain changes in species levels, including increased Lactobacillus letivazi.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus8OpenAlex7
    ScopusPubMedİncele
  • MakaleYalnız künye2017Scopus SJRQ2
    Morphological, Biochemical and Antioxidant Properties of Local Loquat (Eriobotrya Japonica (Thunb.) Lindl.) Germplasm from Turkey; [Morphologische, biochemische und antioxidative Eigenschaften des Zuchtmaterials der Japanischen Wollmispel (Eriobotrya Japonica (Thunb.) Lindl.) aus der Türkei]

    Akbulut, Mustafa; Gozlekci, Sadiye; Ercisli, Sezai; Cakir, Ozlem

    Loquat (Eriobotrya japonica L.) grown well for commercial purposes in subtropical regions nearly 30 countries and originated from China. The most important loquat producers in the world are China, Spain, Turkey, Pakistan, India, Italy and Brazil. In this study, ten pre-selected promising loquat genotypes sampled from eastern Black region and analyzed for their important morphological, biochemical and antioxidant characteristics. The standard cultivar ‘Sayda’ is also included in the study. The results indicated differences for all of the morphological, biochemical and antioxidant characteristics among tested genotypes. Fruit mass and fruit flesh percentage of the genotypes ranged from 35.40 g (LOQ-8) to 46.90 g (LOQ-5) and from 79.40 (%) to 86.32 (%) indicating some local genotypes had higher fruit mass and fruit flesh percentage than standard cultivar ‘Sayda’. Total phenolic content was the highest as 263 μg GAE/g in LOQ-7 genotype while the lowest in LOQ-8 genotype (185 μg GAE/g). LOQ-7 genotype had the highest total antioxidant capacity. Local genotypes in general have higher total phenolic, total carotenoid, vitamin C and antioxidant activity than cv. ‘Sayda’.

    • SDG 2 · Açlığa Son
    AtıfScopus3WoS5OpenAlex4
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2014Scopus SJRQ4
    Some Physicochemical Characteristics, Bioactive Content and Antioxidant Characteristics of Non-Sprayed Barberry (Berberis vulgaris L.) Fruits from Turkey; [Physikalisch-chemische Eigenschaften, bioaktive Inhaltsstoffe und antioxidative Eigenschaften von nicht mit Pflanzenschutzmitteln behandelten Früchten der Berberitze (Berberis vulgaris L.) aus der Türkei]

    Yildiz, Hilal; Ercisli, Sezai; Sengul, Memnune; Topdas, Elif Feyza; Beyhan, Omer; Cakir, Ozlem; Narmanlioglu, Haluk Kemal; Orhan, Emine

    Increasing consumer demands for indigenous, non-sprayed with pesticides and less-known or “forgotten” fruits necessitate knowledge on their breeding, cultivation, biochemical content, harvesting and marketing. Anatolia is rich for wild edible fruit species and barberry is abundant throughout Anatolia. The aim of this study was to determine some important physicochemical characteristics, bioactive content and antioxidant capacity of fruits from nineteen promising barberry (Berberis vulgaris L.) genotypes grown in the Coruh valley, Northeastern Anatolia. The results indicated genotype-specific differences for most of the physicochemical characteristics, antioxidant capacity and the content of some bioactive compounds. Fruit mass ranged from 0.073 (‘Coruh-7’) to 0.267 g (‘Coruh-11’). Total phenolic content ranged from 2532 (‘Coruh-’) to 3719 mg GAE per liter fruit juice (‘Coruh-11’). The genotype ‘Coruh-12’ had the highest total monomeric anthocyanin content (1004 mg per liter fruit juice) as cyanidin-3-glucoside. The highest total antioxidant capacity was observed in fruits of ‘Coruh-8’ and ‘Coruh-9’ genotypes with all three antioxidant-determining methods. We conclude that the barberry fruits represent a good source of bioactive phytochemicals because of their high phenolic and anthocyanin contents.

    • SDG 2 · Açlığa Son
    AtıfScopus34WoS26OpenAlex36
    ScopusWeb of Scienceİncele