Sürdürülebilir Kalkınma Amaçları

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Yazarlar

• Ahmetov, Ildus I.(1)
• Akman, Onur(1)
• Bulgay, Celal(1)
• Cengiz, Mahir Murat(1)
• Erdoğan, Yaşar(1)
• Generozov, Edward V.(1)
• John, George(1)
• Jurko, Damir(1)
• Kazan, Hasan Hueseyin(1)
• Kulemin, Nikolay A.(1)
• Larin, Andrey K.(1)
• Semenova, Ekaterina A.(1)
• Sporis, Goran(1)
• Sultanov, Rinat I.(1)
• Yusupov, Rinat A.(1)
• Zhelankin, Andrey V.(1)
• Çigirtas, Rukiye(1)

• MakaleYayıncıda açık erişim2024Scopus SJRQ2/r/bayburt/10831
  The ARK2N (C18ORF25) Genetic Variant Is Associated with Muscle Fiber Size and Strength Athlete Status

  Çigirtas, Rukiye; Bulgay, Celal; Kazan, Hasan Hueseyin; Akman, Onur; Sporis, Goran; John, George; Yusupov, Rinat A.; Sultanov, Rinat I.; Zhelankin, Andrey V.; Semenova, Ekaterina A.

  Background: Data on the genetic factors contributing to inter-individual variability in muscle fiber size are limited. Recent research has demonstrated that mice lacking the Arkadia (RNF111) N-terminal-like PKA signaling regulator 2N (Ark2n; also known as C18orf25) gene exhibit reduced muscle fiber size, contraction force, and exercise capacity, along with defects in calcium handling within fast-twitch muscle fibers. However, the role of the ARK2N gene in human muscle physiology, and particularly in athletic populations, remains poorly understood. The aim of this study was threefold: (a) to compare ARK2N gene expression between power and endurance athletes; (b) to analyze the relationship between ARK2N gene expression and muscle fiber composition; and (c) to investigate the association between the functional variant of the ARK2N gene, muscle fiber size, and sport-related phenotypes. Results: We found that ARK2N gene expression was significantly higher in power athletes compared to endurance athletes (p = 0.042) and was positively associated with the proportion of oxidative fast-twitch (type IIA) muscle fibers in untrained subjects (p = 0.017, adjusted for age and sex). Additionally, we observed that the ARK2N rs6507691 T allele, which predicts high ARK2N gene expression (p = 3.8 x 10-12), was associated with a greater cross-sectional area of fast-twitch muscle fibers in strength athletes (p = 0.015) and was over-represented in world-class strength athletes (38.6%; OR = 2.2, p = 0.023) and wrestlers (33.8%; OR = 1.8, p = 0.044) compared to controls (22.0%). Conclusions: In conclusion, ARK2N appears to be a gene specific to oxidative fast-twitch myofibers, with its functional variant being associated with muscle fiber size and strength-athlete status.

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  AtıfScopus8·WoS7·OpenAlex8

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• MakaleAçık Erişim2017Scopus SJRQ3/r/bayburt/13927
  Comparison of wintering ability and colony performances of different honeybee (Apis mellifera L.) genotypes in eastern Anatolian/turkey conditions; [Doğu anadolu-Türkiye koşullarinda farklı bal arısı (Apis mellifera L.) genotiplerinin kışlama yeteneği ve koloni performanslarinin karşılaştırılması]

  Cengiz, Mahir Murat; Erdoğan, Yaşar

  In this study, wintering ability and some physiological properties of Buckfast, Carniolan, Caucasian and Erzurum honeybee genotypes were investigated in Eastern Anatolian conditions. During the wintering season of 2014, a total of 48 colonies, 12 from each of Buckfast, Carniolan, Caucasian and Erzurum honey bee genotypes, were taken from the equilibrated colonies of Langstroth type wooden hives for wintering. In the 2015 production period, a total of 43 colonies,11 from each of Buckfast, Carniolan, Erzurum genotypes and 10 from Caucasian genotype were used in the study. In the production season, the average number of combs covered with bees in genotype groups were found as 11.72±0.63, 12.17±0.62, 9.52±0.51 and 10.72±0.55 per colony, and the average brood areas were found as 2713.7±237.9, 2797.6±238.3, 2036.5±166.4, 2364.3±197.2 cm2/colony (19.04.2015-4.10.2015). The difference between the groups was found statistically significant (P<0.01) in terms of number of combs covered with bees and brood areas. Averarage honey yields were determined as 28.08±2.37, 29.94±2.17, 19.28±2.13 and 23.36±2.15 kg/colony, respectively. The difference between groups in honey yield was found statistically significant (P<0.05).

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  AtıfScopus9·WoS5·OpenAlex8

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