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- MakaleAçık Erişim2024Scopus SJRQ2Antioxidant properties and aldose reductase inhibitory potency of Viscum album L. extracts: experimental and computational insights
Akyüz, Bilal; Şengül, Bülent
This study systematically investigates the antioxidant capacity and inhibitory impact of Viscum album L. plant extracts on the aldose reductase (AR) enzyme through a combined approach of in vitro and in silico methods. Various sections derived from distinct plant parts were examined, revealing potent inhibitory potential. Notably, the methanol extract sourced from the plant’s stem displayed remarkable efficacy with an IC50 value of 0.156 µM. Total phenolic content and antioxidant capacity analyses were conducted, highlighting variations across plant parts and solvent types. Qualitative and quantitative phenolic compound content in the extracts was elucidated by LC-MS/MS analysis, revealing higher levels of quinic acid, fumaric acid, and chlorogenic acid. Molecular docking studies further substantiated the inhibitory roles of key compounds like chlorogenic acid and fumaric acid, elucidating their interactions with specific amino acid residues within the AR enzyme’s active site and shedding light on the underlying mechanisms. Collectively, this study underscores Viscum album L. extracts as promising candidates for aldose reductase modulation. By merging experimental and computational techniques, the study presents a holistic understanding of natural compound interactions, potentially influencing drug development and herbal therapeutics.
AtıfScopus4WoS4OpenAlex4
İncele - MakaleAçık Erişim2022Scopus SJRQ3Contributions on the southern distribution of Vespertilio murinus Linnaeus, 1758 (Chiroptera: Vespertilionidae) from Türkiye
Karataş, Ahmet; Bulut, Şafak; Sefali, Abdurrahman; Toprak, Ferhat; Şahin, Mehmet Kürşat; Özkurt, Şakir Önder
Vespertilio murinus Linnaeus, 1758, has a wide distribution from France to Japan, and from Iran in the south to Scandinavia and Russia in the north. The only records of the parti-coloured bat, Vespertilio murinus known from Turkey so far were based on subfossils, remains from owl pellets, and ultrasound recordings. We present the first records of live individuals from two Turkish provinces, Ardahan and Bayburt. Additionally, based on echolocation call records, its known distribution in the Anatolian Peninsula was proved to be wider. The global distribution of the species has been mapped by using ecological niche modelling. The results revealed that its distribution is highly influenced by precipitation dynamics. Although no cases of domestic cat predation on bats have previously been documented in Turkey, this paper also provides the first case study of V. murinus predated by a domestic cat in Ardahan, in November 2003.
AtıfScopus3WoS2OpenAlex2TR Dizin2İncele - MakaleAçık Erişim2019Scopus SJRQ2Fruit and seed macro- and micromorphologies of the genus Matthiola (Brassicaceae) in turkey and their taxonomic value
Kaya, Ayla; Ünal, Murat; Sefali, Abdurrahman; Martin, Esra
Macro- and micromorphological features of fruit and seeds belonging to 12 taxa genera of Matthiola W.T.Aiton were studied via stereomicroscope and scanning electron microscope. In macromorphological studies, the following variables were investigated: The shape, size, and color of fruit and seeds; the length of fruiting pedicel; the structure of the median vein; stigma (horns); and trichome properties and density in fruit. In micromorphological studies, the presence or absence of seed wings, seed coat pattern in disc and wing, and epidermal cell shape in disc and wing were determined. According to our findings, all characters of fruit and seeds are extremely variable and can be used as criteria to distinguish species of the genus.
AtıfScopus5WoS4TR Dizin1İncele - MakaleAçık Erişim2015Scopus SJRQ3Some new records and one new species of the genus Lebertia Neuman (Acari: Hydrachnidia: Lebertiidae) from Turkey
Esen, Yunus; Erman, Orhan
In this study, water mites of the genus Lebertia Neuman, 1880 (Acari: Hydrachnidia) collected from Antalya, Artvin, Bingöl, Erzurum, Kahramanmaras, and Siirt provinces of Turkey are presented. In total, 12 species were determined. Of these, Lebertia (s. str.) marasensis sp. nov. is described as new to science, while L. (s. str.) rufipes Koenike, 1902; L. (Pilolebertia) longiseta Bader, 1955; L. (Pilolebertia) pilosa Maglio, 1924; L. (Mixolebertia) separata Lundblad, 1930; and L. (Brentalebertia) minutipalpis K. Viets, 1920 are new records for the Turkish fauna.
AtıfScopus1WoS1OpenAlex2İncele - MakaleAçık Erişim2011Scopus SJRQ2Determination of protein and gluten quality-related parameters of wheat flour using near-infrared reflectance spectroscopy (NIRS); [Yakın Kızılötesi Spektroskopisi (NIRS) kullanarak buǧday unlarının protein ve glutenle ilgili kalite parametrelerinin belirlenmesi]
Başlar, Mehmet; Ertugay, Mustafa Fatih
Wet chemistry analyses done for quality control purposes in wheat and flour processing are time-consuming. Near-infrared spectroscopy (NIRS) as an alternative technology to conventional methods allows us to obtain results in a few seconds. In this study, NIRS was used in the development of calibration models for protein, wet and dry gluten contents and Zeleny sedimentation of flours from the grinding of 120 varieties of bread wheat collected from different regions of Turkey. Therefore, spectra in the range of 1100 to 2500 nm of the flours were acquired by scanning with the NIRSystems 6500 monochromator. Multiple linear regression (MLR) and partial least squares (PLS) regression were applied to the spectral data in log 1/R, and first derivative and second derivative of log 1/R formats. Reasonable results were obtained for protein, wet and dry gluten contents, and Zeleny sedimentation with r = 0.985, 0.976, 0.953, and 0.924, respectively.
AtıfScopus41WoS38OpenAlex52İncele - DergiTurkish Journal of Zoology