Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2026Association of the enteral nutrition support with mortality, biochemical parameters, and health markers in geriatric patients with COVID-19: A retrospective cohort study
Özçelik, Ayşe Özfer; Esgin, Ozge; Ethemoğlu, Filiz Banu; Özyürek, Serkan; Aykırı, Hilal
This study aims to evaluate the association of the enteral nutrition support on mortality, biochemical parameters, and health markers in geriatric patients with COVID-19 treated in intensive care units (ICUs). A retrospective cohort analysis was conducted on 226 patients aged 60 years and older admitted to the COVID-19 adult ICU of Yıldırım Beyazıt University Training and Research Hospital in 2021. Demographics, ICU stay characteristics, biochemical parameters, and nutrition therapy details were collected from hospital records. Patients receiving enteral nutrition were categorized by product type (e.g., diabetic, immunonutrition, glutamine-containing, etc.), and their association on mortality, biochemical markers, and ICU outcomes were evaluated. The mortality rate was 50.4%, with an mean ICU stay of 9.63±6.50 days. Most patients (90.3%) had chronic conditions. Nutrition therapy was administered to 138 patients using various products. Immunonutrition products were associated with improved albumin levels and reduced mortality (p<0.05). Chronic conditions significantly increased mortality risk and ICU stay duration (p<0.05). Multivariate analysis revealed that longer ICU stays and the presence of chronic diseases independently reduced survival probability. Enteral nutrition support, particularly immunonutrition, may benefit geriatric ICU patients with COVID-19 by improving biochemical parameters and reducing mortality risk. Although patients receiving diabetic and glutamine-enriched products have a higher incidence of pressure ulcers, it should be considered that such products are likely to have been used in higher-risk patients.
- MakaleAçık Erişim2025Scopus SJRQ1Cultural adaptation and psychometric validation of the Turkish MIND diet adherence scale for young adults
Esgin, Özge; Aslan Çin, Nazlı Nur; Kaplan, Özlem Nur; Baratzada, Leeda; Özçelik, Ayşe Özfer
Background: The MIND diet, which promotes brain health, has a potential role in preventing cognitive decline. To further establish its applicability, it is essential to validate the MIND Diet Adherence Scale in different populations with diverse dietary habits, including Turkish young adults. Objective: The aim of this study was to evaluate the construct validity, internal consistency and test-retest reliability of the Turkish version of the MIND diet assessment tool in the Turkish population. Methods: A total of 310 individuals aged between 19 and 39 (mean age 25.0 ± 5.1) voluntarily participated in this study. Data were collected through face-to-face interviews, incorporating socio-demographic characteristics, anthropometric measurements, the MIND Diet Adherence Scale, and the Mediterranean Diet Adherence Scale. Both exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) of the MIND Dietary Adherence Scale were performed. In the CFA, the goodness of fit of the hypothesized model to the observed data was evaluated using a range of fit indices. Results: The study determined an adequate sample size (KMO = 0.67), with sufficient item correlations for factor analysis (χ2 = 449.74; p < 0.001). Confirmatory factor analysis and goodness-of-fit indicators supported the fit of the two-factor model to the Turkish data. The Cronbach’s alpha internal consistency coefficient for the MIND Diet Adherence Scale was 0.61. All items in the scale exhibited a positive correlation with the total score, exceeding 0.40. Furthermore, a substantial positive correlation was observed between the Mediterranean Diet Adherence Scale and the MIND Diet Adherence Scale. Conclusions: The Turkish adaptation of the MIND Diet Adherence Scale can be utilized in its entirety, without the need to remove any items. This study affirms that the MIND Diet Adherence Scale is a valid and reliable measurement tool for assessing dietary habits in Turkish society.
AtıfScopus3WoS3OpenAlex2
İncele - MakaleAçık Erişim2025Scopus SJRQ2Mind diet adherence associated with lower Zonulin levels in older Parkinson's patients
Esgin, Özge; Tokçaer Bora, Hatice Ayşe; Gülbahar, Özlem; Demirkesen, Özlem Cemile; Ataoğlu, Nigar Esra Erkoç; Söke, Fatih; Özçelik, Ayşe Özfer
Aim: This study investigates the association between adherence to the MIND diet and serum zonulin levels in older adults with Parkinson's disease (PD). Methods: Data were collected through structured survey forms and blood samples. The survey assessed general information, 24-hour food recalls, anthropometric measurements, the MIND diet adherence and physical activity levels. Zonulin levels were analysed from blood samples. Results: The study included 57 older adults with PD in stages 1–3 on the Hoehn & Yahr scale (29 women, 28 men; mean age 70.2 ± 4.6 years). Zonulin levels were negatively correlated with dietary total antioxidant capacity (p < 0.05). In adjusted analyses, higher adherence to the MIND diet was associated with lower zonulin levels (β = −0.25). Conclusions: These findings suggest a novel link between adherence to the MIND diet and reduced zonulin levels. MIND diet could have potential benefits for neurological function and intestinal barrier integrity.
