Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2025Scopus SJRQ4/r/bayburt/12810
  DFT Calculations, ADME Analysis and Molecular Docking Studies of the Compound AHTPO With the Digestive Enzyme Trypsin Found in Cold-Adapted Fish Species

  Tanrıverdi, Erdi Anıl; Tanrıverdi, Aslıhan Aycan; Yıldıko, Ümit

  For the special amine 7-Amino-3-(4-aminophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (AHTPO), previously reported experimental biological activities served as the foundation for further studies. Computational chemistry and molecular simulation techniques were subsequently applied to investigate AHTPO. Its interactions with trypsin enzymes derived from cold-adapted fish species were examined. The compound's biological activity and pharmacokinetic properties were assessed using DFT calculations, molecular docking, and ADME analyses. Molecular docking results indicated that AHTPO exhibits strong binding affinities with the 1A0J and 2TBS enzymes, with the binding to 2TBS being energetically more favorable. Additionally, ADME analysis revealed that while the AHTPO shows potential for pharmaceutical applications, its gastrointestinal absorption and blood-brain barrier permeability may present certain limitations. Regarding its electronic and optical properties, AHTPO's high dipole moment and polarizability values enhance its flexibility and adaptability in biological environments. The HOMO-LUMO energy gap suggests that the AHTPO achieves a balance between stability and reactivity, enabling high activity in biomolecular interactions. These findings highlight the promising pharmacological potential of AHTPO in binding with trypsin enzymes, suggesting its viability as a therapeutic agent.

  AtıfScopus1·OpenAlex1

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• MakaleAçık Erişim2025Scopus SJRQ4/r/bayburt/11424
  Effect of Plasma Electrolytic Oxidation Process on Corrosion Resistance of Al-Coated AZ61 Magnesium Alloy

  Durna, İdris; Çatar, Recep; Altun, Hikmet

  Magnesium alloys are extensively utilized in aerospace, aviation, and automotive sectors due to their low density and high specific strength, which offer significant advantages for lightweight structural applications. Their low density especially directs the attention of the aviation sector, where lightness is necessary, to these alloys. However, one of the disadvantages that restricts their use in the industry is their low corrosion resistance. In this study, the Plasma Electrolytic Oxidation (PEO) process was applied in a silicate-based electrolyte to AZ61 magnesium alloy pre-coated with aluminum using the electric arc spraying technique. To examine the characteristics of the fabricated coatings, their phase structures, surface features, and elemental compositions were investigated through XRD, SEM, and EDS analyses. Corrosion performances of coatings were investigated by potentiodynamic polarization test in 3.5% NaCl solution. As a result of electrochemical tests, corrosion current density values for the base sample (AZ61) and PEO coating (AZ61-PEO) were determined as 36,29 μA. cm−2 and 6,53 μA. cm−2, respectively. The findings highlight that the Al₂O₃ layer formed following PEO treatment significantly enhanced the corrosion resistance compared to the base sample.

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• MakaleAçık Erişim2023/r/bayburt/12906
  Analysis of occupational health and safety risks in beekeeping with fmea method

  Özdemir, Mustafa; Kökhan, Serhan

  Contrary to popular belief, beekeeping, which dates back to prehistoric times and is one of the most important plant and animal production branches today, is not an innocent profession in terms of occupational health and safety. In this study, in order to determine the occupational health and safety risk factors in the beekeeping profession, Interviews with beekeepers were conducted in 10 apiaries operating in Bayburt, where especially wandering beekeeping is practiced. In light of the data obtained from the danger hunt applied by the occupational health and safety specialist, ergonomic, physical, biological, and chemical risks were revealed using the FMEA risk analysis method. The effect, probability, and detection values were found for each failure mode, and then Risk Priority Number values were calculated. As a result of the study, for the five basic stages of beekeeping, 15 processes, 39 failure modes, 72 potential effects, and 39 failure causes were determined. Failure modes with a Risk Priority Number value of 100 and above were evaluated as “situations where urgent action and axiom should be taken,” and preventive axioms were proposed for each relevant failure mode. The number of studies on the risk factors in the beekeeping profession is very limited in the literature. For this reason, it is predicted that this study will fill an important gap in the related field and make significant contributions to the literature.

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  AtıfScopus3·OpenAlex3

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• MakaleAçık Erişim2020/r/bayburt/12129
  Optimization of exopolysaccharide production of Lactobacillus brevis E25 using RSM and characterization

  Ermis, Ertan; Poyraz, Ecem; Dertli, Enes; Yilmaz, Mustafa Tahsin

  Response surface methodology was used to determine the exopolysaccharide production of Lactobacillus brevis E25. The effects of three variables, temperature (30, 36 and 42 °C), incubation time (18, 33 and 48 h) and initial pH of growth medium (4.5, 5.5, and 6.5) were studied. Under optimum growth conditions, the amount of exopolysaccharide derived from Lactobacillus brevis E25 ranged from 10 to 35 gL-1. The size of EPS molecules ranged from 105 to 107 Da. Infra red spectrum analysis showed characteristics absorption peaks indicating the presence of-OH, C=O and C-H groups. Furthermore, only glucose was detected as monosaccharide in exopolysaccharide structure, revealing that the structure of exopolysaccharide is a homopolymeric glucan type. Based on the differential scanning calorimeter thermograms, exopolysaccharide’s melting temperature was observed around 116 °C.

  AtıfScopus18·OpenAlex18

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• MakaleAçık Erişim2020/r/bayburt/12077
  Investigation of Beam Width Shaping of a Ku-band Horn Antenna using a Diffractive Optic Element and an Electromagnetic Wave Absorber

  Teber, Ahmet

  The feasibility of beam-shaping of a Ku-Band horn as a transmitting (Tx) antenna by mounting two different versions of lenses which are kind of Fresnel Zone Plates (FZP) is studied. The designed and fabricated geometrical structures offer a simpler approach building Fresnel Zone Plates by using an electromagnetic wave absorber and diffractive optic material. The diffractive optic material, paraffin, forms a set of alternating open and opaque annular zones on a flat surface, based on the design principles of Fresnel Zone Plates. An electromagnetic wave absorber covers the top surface of the formed paraffin, but not including the grooves. Thereafter, the Fresnel Zone plates are suitably attached in front of the transmitter horn antenna, located in the far-field region of a receiving antenna. The half-power beam-widths for the horn antenna (unloaded) and with two types of lenses are investigated. The results indicate that Fresnel zone plate structures can play a role suppressing side lobes in H-plane so that the effective radiation is to be significantly concentrated.

  AtıfScopus1·OpenAlex2

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• MakaleAçık Erişim2018/r/bayburt/15250
  Application of statistical process control method to monitor wear and broken tooth faults in spur gears using vibration data

  Arslan, Hakan; Maraş, Sinan

  Gears are machine elements used extensively in many areas of industry to transmit power and motion. Damage occurs due to working under compulsive conditions effective gear fault detection is crucial to prevent greater drawbacks and economic losses. The objective of this study is to monitor the existence of different types of gear defects by examining changes in the vibrations of spur gears due to faults using vibrations analysis and statistical process control methods. For this purpose, a closed-loop test rig was constructed. Firstly, good gears were attached to the test assembly and vibrations data which received at radial direction via sensors on the bearings were recorded by operating the system at various loading and number of cycle’s conditions. Thus, a reference spectrum was obtained. Then the system was operated with artificial wear and fracture which were created on the surfaces of spur gears at various loading and number of cycles conditions. Vibrations data which were received from the bearings were recorded. These data were plotted on statistical control carts and frequency spectrum. Graphs of data obtained from good gears and defective gears were compared with each other. Thus it was possible to detect the existence of worn gear, one tooth broken pinion gear and one tooth broken from each pinion and wheel gears.

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  AtıfTR Dizin1

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• MakaleYalnız künye2016/r/bayburt/15457
  EKDZ modelinin farklı bina dağılımları içeren senaryolara uygulanarak eğim kırınımı etkisinin araştırılması

  Tabakcıoğlu, Mehmet Barış; Çorapsız, Muhammed Reşit

  Bu çalışmada, karasal radyo yayıncılığında kullanılan bazı yayılım modelleri kısaca anlatılacak, daha sonra EKDZ veUKT yayılım modelleri kullanılarak benzetimler yapılacaktır. Bu benzetimler için kullanılacak senaryolar bazıistatistiksel ve geometrik dağılımlar kullanılarak belirlenecektir. Bu dağılımlar üzerinden yapılacak benzetimlersonucunda eğim kırınımı etkisi tartışılacaktır.

  AtıfTR Dizin1

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• MakaleYalnız künye2016/r/bayburt/15455
  A study on drought stress tolerance in some maize (Zea mays L.) cultivars

  Bayram, Nesrin Ecem; Dogru, Ali

  Bu çalışmada üç mısır (Zea mays L.) kültivarının (FR13, FRB73, TTM815) kuraklık stresine toleranslarının araştırılması amacıyla bazı morfolojik ve fizyolojik parametreler analiz edilmiştir. Yirmi bir günlük bitkilere, Hoagland besin çözeltisi uygulaması sonlandırılarak 2 (hafif kuraklık stresi), 5 (orta dereceli kuraklık stresi) ve 8 (şiddetli kuraklık stresi) gün olmak üzere üç farklı kuraklık rejimi uygulanmıştır. FR13 ve TTM815 kültivarlarında orta dereceli ve şiddetli kuraklık stresi kök büyümesini önemli derecede inhibe ederken, gövde büyümesi mısır kültivarlarında tüm kuraklık uygulamalarından etkilenmemiştir. Elde ettiğimiz sonuçlar mısır kültivarlarında hafif ve orta dereceli kuraklık stresi koşullarında toplam bitki boyundaki azalmanın, kök büyümesindeki inhibisyondan kaynaklandığını ancak FRB73'ün daha az etkilendiğini göstermiştir. Tüm kültivarlarda kuraklık uygulamaları taze ve kuru biyomasın artmasına neden olmuş fakat FRB73'de daha belirgin bir artış meydana gelmiştir. Bu sonuçlar kuraklık koşulları altında nispeten daha stabil su miktarına sahip olduğu için FRB73'deki su ilişkilerinin daha uygun şekilde regüle edildiğini göstermektedir. FR13 ve TTM815'de "klorofil a" miktarı uygulamalar sonunda azalırken, FRB73'de kuraklık stresinden etkilenmemiştir. Diğer yandan FR13 ve FRB73'de "klorofil b" içeriği kuraklık uygulamalarından daha az etkilenmiştir. Kuraklık uygulamaları sonucunda tüm kültivarlardaki malondialdehit birikimi önemli derecede artmış ancak FRB73'de daha az birikim belirlenmiştir. Toplam fenolik madde içeriği tüm kültivarlarda özellikle orta dereceli ve şiddetli kuraklık sonucunda artmıştır. FR13 ve TTM815'de toplam çözünür şeker miktarı orta dereceli ve şiddetli kuraklık uygulamaları sonucu azalırken, FRB73'de değişmemiştir. Elde ettiğimiz sonuçlara göre FRB73'ün, FR13 ve TTM815 ile karşılaştırıldığında, kuraklık stresi altında kök ve gövde büyümesini sürdürme yeteneği, fenolik madde, taze ve kuru biyomas artışı, su, fotosentetik pigment (klorofil a ve b) ve şeker miktarının daha az etkilenmesi ve malondialdehit birikiminin daha az olması nedeniyle kuraklığa daha toleranslı bir mısır kültivarı olduğu söylenebilir

  AtıfTR Dizin1

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