Sürdürülebilir Kalkınma Amaçları

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• Derleme MakaleAçık Erişim2026Scopus SJRQ1/r/bayburt/11447
  The role of biotics and bioactive compounds in sports injuries: a narrative review

  Şahin-Demirci, Kezban; Dal, Nursel; Gönen-Çolak, Buket; Akman, Onur; Raposa, Bence; Ağagündüz, Duygu

  Sports injuries affect not just the physical, but also the psychological, social, and professional aspects of athletes’ lives. Preventive strategies, nutrition, and nutritional supplements—especially biotics and bioactive compounds—are crucial for recovery and may help prevent injury recurrence. This review examines biotics and bioactive compounds that may be effective on sports injuries, revealing their potential benefits and safety of use. Using a comparative and interpretive approach, the pertinent literature was thoroughly examined for this review, with a special focus on clinical and preclinical research conducted within the last 5 years. Bioactive compounds and biotics (prebiotics: indigestible substances that support beneficial bacteria; probiotics: live beneficial microorganisms; postbiotics: bioactive microbial metabolites) can improve sports-related injuries by affecting inflammation, mitochondrial function, biogenesis, oxidative stress, and atrophy. Biotics achieve these systemic effects by improving intestinal barrier function and modulating the microbiota. Current literature indicates that some compounds show promise for treating sports injuries, but human study evidence is limited. Animal models provide useful insights for future research. Finally, polyphenolic compounds, amino acids/peptides, and w-3 fatty acids, thanks to their anti-inflammatory and antioxidant properties, can indirectly contribute to muscle regeneration and cell repair, thus supporting the recovery process in athletes. However, it is still too early to make recommendations regarding the use of biotics and bioactive compounds in sports injuries.

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• MakaleYalnız künye2026Scopus SJRQ2/r/bayburt/11339
  The effect of practising sports on communication skills in medical students

  Kaşali, Kamber; Badicu, Georgian; Al-Mhanna, Sameer Badri; de Sousa Fernandes, Matheus Santos; Şeran, Buket; Akman, Onur

  Effective communication is essential for medical students in terms of patient interaction, teamwork and professional success. This study examines the effect of doing sports on the communication skills of medical students. Three hundred forty-five medical students participated in the study and their communication skills were assessed using the Effective Communication Skills Scale. The findings revealed a significant difference between Turkish and English students in terms of 'Using I Language' skills. In addition, when the students' beliefs about the physical, physiological and psychological benefits of sports were compared with the sub-dimensions of the scale, statistically significant differences were found in the sub-dimensions of "Ego Enhancing Language" (p = 0.011), "Empathy" (p = 0.047) and "Using I Language" (p = 0.005). When the relationship between the class levels of the students and the sub-dimensions of the scale was examined, significant differences were observed in the sub-dimensions of 'Ego Enhancing Language' (p = 0.001), 'Active Listening' (p = 0.011) and 'Using I Language' (p = 0.007). The findings show that doing sports is essential in improving medical students' communication skills and suggest that encouraging sports in the medical education process may be beneficial in enhancing communication competencies.

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  AtıfOpenAlex1

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• MakaleAçık Erişim2026Scopus SJRQ3/r/bayburt/10946
  Frequency spectrum analysis of ground reaction forces during running in individuals with piriformis syndrome following an eight-week neuromuscular training program

  Aali, Shirin; Rezazadeh, Farhad; Sheykhalizadeh, Hamed; Qasemi, Mojtaba; Akman, Onur; Badicu, Georgian

  Background: Piriformis syndrome, a neuromuscular condition associated with sciatic nerve irritation, can disrupt lower limb biomechanics and alter ground reaction force (GRF) profiles during running. Neuromuscular training may improve lumbopelvic stability and coordination, but its effects on GRF frequency characteristics remain underexplored. Methods: Thirty physically active males (aged 35–45 years) with piriformis syndrome were recruited and allocated to either an intervention group (n = 15) or a control group (n = 15) in this quasi-experimental study. The intervention group completed an eight-week neuromuscular training protocol designed to enhance lumbopelvic stability and coordination. Vertical and free moment GRF components were recorded during treadmill running before and after the intervention. Temporal and group effects were analyzed using a two-way repeated-measures Analysis of Variance (ANOVA). Results: The intervention group exhibited a significant reduction in the number of harmonics in the vertical GRF component (p = 0.003, d = 0.55) and a decrease in the 99.5% power frequency of the free moment component (p = 0.001, d = 0.92). These changes reflected diminished high-frequency oscillations, suggesting improved eccentric muscle function, lumbopelvic control, and neuromuscular coordination. Conclusions: Neuromuscular training resulted in favorable alterations in GRF frequency spectra among individuals with piriformis syndrome, aligning with reductions in pain and indicating more efficient force transfer and load attenuation. These findings support the application of neuromuscular training to optimize running biomechanics and reduce mechanical stress in this population.

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• MakaleAçık Erişim2025/r/bayburt/14073
  The Revelation of Linear and Change of Direction HIIT Training Effects on the Anaerobic Power of Female Football Players

  Morina, Besnik; Visic, Grgur; Antonic, Davorin; Babic, Matej; Sporis, Goran; Franjko, Ivica; Tomac, Zvonimir; Akman, Onur; Miletic, Aleksandar; Krasniqi, Rrezon

  Background. Anaerobic and aerobic power are critical factors influencing peak football performance. This study aimed to explore the differential effects of various high-intensity interval training (HIIT) protocols on these performance metrics in senior female football players. Objectives. The primary objective was to investigate the impact of linear (L) HIIT and change-of-direction (COD) HIIT protocols on key velocity at anaerobic threshold (V-AT), distance traveled in the anaerobic zone (d(AT)), and VO(2)max. Methods. Sixty senior female football players were divided into LHIIT (n=30) and COD (n=30). Both groups underwent initial testing before participating in their respective training programs for four weeks. Performance metrics were measured at the beginning and end of the training period. Results. Both groups significantly improved all measured variables (p<0.001). However, the COD group demonstrated relatively more significant enhancements in Vmax (COD=0.93; LHIIT=0.8), VAT (COD=0.94; LHIIT=0.87), and VO(2)max (COD=0.92; LHIIT=0.74). The COD group also reduced the initial difference in VO(2)max to a non-significant level. Conclusion. COD HIIT protocols appear to be slightly more effective in enhancing anaerobic power in female football players than linear HIIT protocols. Nevertheless, both HIIT programs significantly improved performance metrics, indicating that incorporating such training regimens can benefit female football training programs.

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• MakaleAçık Erişim2025Scopus SJRQ3/r/bayburt/10866
  EUROFIT Reference Values of 7-11 Aged Children in Urban Areas of Kosovo: Relations between Age and Gender

  Gjinovci, Bahri; Morina, Besnik; Sporiš, Goran; Nikqi, Valon; Akman, Onur; Jurko, Damir; Osmani, Arta; Grle, Maki; Grle, Ivana; Prlić, Jerko

  This study establishes EUROFIT reference values for physical fitness and anthropometric measurements in children aged 7-11 years in urban Kosovo. Analyzing data from 500 participants, the study examines age- and sex-based variations in motor abilities and morphological traits. Data was collected over three months, from April through June 2023, in a typical school setting during regular physical education class times. This environment was typically utilized by students to reduce performance variability caused by external conditions. Results reveal age-related increases in height, weight, and strength measures, consistent with growth trends during childhood. Boys showed higher performance in strength and power tests, while girls exhibited greater flexibility. The EUROFIT battery proved effective for assessing physical fitness across age groups. This research fills a data gap in Kosovo, providing valuable reference values for educators, coaches, and policymakers aiming to promote children’s health and physical activity.

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  AtıfScopus1·OpenAlex1

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• MakaleYayıncıda açık erişim2024Scopus SJRQ2/r/bayburt/10831
  The ARK2N (C18ORF25) Genetic Variant Is Associated with Muscle Fiber Size and Strength Athlete Status

  Çigirtas, Rukiye; Bulgay, Celal; Kazan, Hasan Hueseyin; Akman, Onur; Sporis, Goran; John, George; Yusupov, Rinat A.; Sultanov, Rinat I.; Zhelankin, Andrey V.; Semenova, Ekaterina A.

  Background: Data on the genetic factors contributing to inter-individual variability in muscle fiber size are limited. Recent research has demonstrated that mice lacking the Arkadia (RNF111) N-terminal-like PKA signaling regulator 2N (Ark2n; also known as C18orf25) gene exhibit reduced muscle fiber size, contraction force, and exercise capacity, along with defects in calcium handling within fast-twitch muscle fibers. However, the role of the ARK2N gene in human muscle physiology, and particularly in athletic populations, remains poorly understood. The aim of this study was threefold: (a) to compare ARK2N gene expression between power and endurance athletes; (b) to analyze the relationship between ARK2N gene expression and muscle fiber composition; and (c) to investigate the association between the functional variant of the ARK2N gene, muscle fiber size, and sport-related phenotypes. Results: We found that ARK2N gene expression was significantly higher in power athletes compared to endurance athletes (p = 0.042) and was positively associated with the proportion of oxidative fast-twitch (type IIA) muscle fibers in untrained subjects (p = 0.017, adjusted for age and sex). Additionally, we observed that the ARK2N rs6507691 T allele, which predicts high ARK2N gene expression (p = 3.8 x 10-12), was associated with a greater cross-sectional area of fast-twitch muscle fibers in strength athletes (p = 0.015) and was over-represented in world-class strength athletes (38.6%; OR = 2.2, p = 0.023) and wrestlers (33.8%; OR = 1.8, p = 0.044) compared to controls (22.0%). Conclusions: In conclusion, ARK2N appears to be a gene specific to oxidative fast-twitch myofibers, with its functional variant being associated with muscle fiber size and strength-athlete status.

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  AtıfScopus8·WoS7·OpenAlex8

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• MakaleAçık Erişim2023Scopus SJRQ2/r/bayburt/10859
  Exome-Wide Association Study of Competitive Performance in Elite Athletes

  Bulgay, Celal; Kasakolu, Anil; Kazan, Hasan Hueseyin; Mijaica, Raluca; Zorba, Erdal; Akman, Onur; Bayraktar, Isik; Ekmekci, Ridvan; Koncagul, Seyrani; Ulucan, Korkut

  The aim of the study was to identify genetic variants associated with personal best scores in Turkish track and field athletes and to compare allelic frequencies between sprint/power and endurance athletes and controls using a whole-exome sequencing (WES) approach, followed by replication studies in independent cohorts. The discovery phase involved 60 elite Turkish athletes (31 sprint/power and 29 endurance) and 20 ethnically matched controls. The replication phase involved 1132 individuals (115 elite Russian sprinters, 373 elite Russian endurance athletes (of which 75 athletes were with VO2max measurements), 209 controls, 148 Russian and 287 Finnish individuals with muscle fiber composition and cross-sectional area (CSA) data). None of the single nucleotide polymorphisms (SNPs) reached an exome-wide significance level (p < 2.3 x 10(-7)) in genotype-phenotype and case-control studies of Turkish athletes. However, of the 53 nominally (p < 0.05) associated SNPs, four functional variants were replicated. The SIRT1 rs41299232 G allele was significantly over-represented in Turkish (p = 0.047) and Russian (p = 0.018) endurance athletes compared to sprint/power athletes and was associated with increased VO2max (p = 0.037) and a greater proportion of slow-twitch muscle fibers (p = 0.035). The NUP210 rs2280084 A allele was significantly over-represented in Turkish (p = 0.044) and Russian (p = 0.012) endurance athletes compared to sprint/power athletes. The TRPM2 rs1785440 G allele was significantly over-represented in Turkish endurance athletes compared to sprint/power athletes (p = 0.034) and was associated with increased VO2max (p = 0.008). The AGRN rs4074992 C allele was significantly over-represented in Turkish sprint/power athletes compared to endurance athletes (p = 0.037) and was associated with a greater CSA of fast-twitch muscle fibers (p = 0.024). In conclusion, we present the first WES study of athletes showing that this approach can be used to identify novel genetic markers associated with exercise- and sport-related phenotypes.

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  AtıfScopus20·WoS23·OpenAlex27

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• MakaleAçık Erişim2023Scopus SJRQ2/r/bayburt/10838
  Evaluation of the Association of VDR rs2228570 Polymorphism with Elite Track and Field Athletes' Competitive Performance

  Bulgay, Celal; Bayraktar, Isik; Kazan, Hasan Huseyin; Yildirim, Damla Selin; Zorba, Erdal; Akman, Onur; Ergun, Mehmet Ali; Cerit, Mesut; Ulucan, Korkut; Eken, Ozgur

  The present study aimed to examine the vitamin D receptor (VDR), rs2228570 polymorphism, and its effect on elite athletes' performance. A total of 60 elite athletes (31 sprint/power and 29 endurance) and 20 control/ physically inactive, aged 18-35, voluntarily participated in the study. The International Association of Athletics Federations (IAAF) score scale was used to determine the performance levels of the athletes' personal best (PB). Whole exome sequencing (WES) was performed by the genomic DNA isolated from the peripheral blood of the participants. Sports type, sex, and competitive performance were chosen as the parameters to compare within and between the groups by linear regression models. The results showed no statistically significant difference between the CC, TC, and TT genotypes within and between the groups (p > 0.05). Additionally, our results underlined that there were no statistically significant differences for the association of rs2228570 polymorphism with PBs within the groups of the (p > 0.05) athletes. The genetic profile in the selected gene was similar in elite endurance, sprint athletes, and in controls, suggesting that rs2228570 polymorphism does not determine competitive performance in the analyzed athlete cohort.

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  AtıfScopus11·WoS10·OpenAlex15

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• MakaleAçık Erişim2022/r/bayburt/16707
  PPARGC1A Gen Polimorfizmi (rs8192678) ile Elit Sporcuların Yarışma Performansları Arasındaki İlişkinin Değerlendirilmesi

  Bayraktar, Işık; Zorba, Erdal; Ulucan, Korkut; Bulğay, Celal; Ergun, Mehmet Ali; Kazan, Hasan; Akman, Onur

  PPARGC1A (rs8192678) gen polimorfizmi ve atletik performans arasıdaki ilişkiler konusunda sınırlı sayıda araştırma mevcuttur. Bu nedenle, bu çalışmada PPARGC1A genindeki rs8192678 polimorfizminin Türk elit atletizm sporcularının yarışma performansları ile olası ilişkisin araştırılması amaçlamaktadır. Çalışmaya 18-35 yaşları arasında toplam 60 elit sporcu (31 sprint/güç ve 29 dayanıklılık) ve 20 kontrol/sedanter gönüllü olarak katıldı. Atletlerin kişisel en iyi (PB)/yarışma performans düzeylerini belirlemek için Uluslararası Atletizm Federasyonları Birliği (IAAF) puan ölçeği kullanıldı. Tüm ekzom dizilimi (WES), katılımcıların kanından izole edilen genomik DNA tarafından gerçekleştirildi. rs8192678 polimorfizmi ile PB arasındaki ilişki, cinsiyet ve spor deneyimi ayarlaması ile tek yönlü kovaryans analizi (ANCOVA) ile incelendi. Bulgulara göre grup içi ve gruplar arasında, G/G, G/A ve A/A genotip dağılımları arasında anlamlı bir farklılık tespit edilmemiştir (p>0.05). Sonuç olarak, PPARGC1A rs8192678 polimorfizmi ile sporcuların performansı arasında anlamlı hiçbir ilişki tespit edilmemiştir. Ancak, yapılan araştırma hakkında daha net bilgi verebilmek için daha fazla katılımcı ile yapılması önerilir.

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  AtıfOpenAlex4

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• MakaleAçık Erişim2021Scopus SJRQ3/r/bayburt/12003
  The validity and reliability study of who quality of life scale short form (whoqol-bref) in Kazakh language

  Yermakhanov, Baglan; Zorba, Erdal; Turkmen, Mutlu; Akman, Onur

  The purpose of the current study is to test the validity and reliability of WHO quality of life scale short form (WHOQOLBref ) in Kazakh language. In this sense, a total sum of 509 students, 208 men (40.9%) and 301 women (59.1), volunteered in the study. The scale was made up of 26 items and 5 sub-dimensions (General Health, Physical Health, Psychological Health, Social Relations and Environment). In the analysis of the study, Confirmatory Factor Analysis was used regarding the structural validity of the inventory and Cronbach Alpha reliability analysis was used to determine internal consistency. In the confirmatory factor analysis results, goodness of fit index values were found as x2/sd(x2=936.08, sd=289)=3.23, GFI=0.88, CFI=0.86, NFI=0.80, RMSEA=0.66, SRMR=0.52, RMR=0.47. Internal consistency coefficient numbers were determined as 0.60 and 0.90. As a conclusion, it is likely to say that "WHO Quality of Life Scale Short Form (WHOQOL-Bref ) in Kazakh Language" is a valid and reliable assessment tool.

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  AtıfScopus4·OpenAlex4

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