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  • MakaleAçık Erişim2025Scopus SJRQ2
    The Relationship Between Metacognitive Beliefs and Salivary Cortisol, BDNF, and NDNF Levels: A Cross-Sectional Study

    Okur, Süheyb; Bayraktar, Bülent; Tosun Köse, Fatma

    Purpose: The main objective of this study is to non-invasively investigate the relationship between metacognitive beliefs and cortisol, the primary stress output of the hypothalamic-pituitary-adrenal (HPA) axis, as well as neurotrophic factors associated with neuroplasticity brain-derived neurotrophic factor and neuron-derived neurotrophic factor (BDNF and NDNF). Within this framework, the hypotheses that negative metacognitions would be associated with increased cortisol and decreased BDNF levels, and that cortisol might play a mediating role in this relationship, were tested. Method: The study was designed in a cross-sectional model with 60 university students. Participants' metacognitive beliefs were measured using the Metacognitions Questionnaire-30 (MCQ-30). Salivary cortisol, BDNF, and NDNF levels were analyzed using the ELISA method. Pearson correlation and hierarchical multiple regression analyses were used for data analysis. Finding: The results showed a significant positive relationship between the total metacognition score and cortisol (r = 0.589, p < 0.01) and a strong negative relationship between cortisol and BDNF (r = −0.662, p < 0.01). Hierarchical regression analysis supported a partial mediation model, indicating that dysfunctional metacognitive beliefs have both a significant direct negative association with BDNF and an indirect association mediated by cortisol. In the final model, both metacognition (β = –0.298, p < 0.05) and cortisol (β = –0.281, p < 0.05) were significant factors associated with lower BDNF levels. NDNF showed a positive relationship with BDNF (r = 0.571) but not with other variables. Conclusion: These findings point to a psychobiological model where dysfunctional metacognitive beliefs are linked to suppressed neuroprotective mechanisms like BDNF, both directly and indirectly through HPA axis activation. The results shed light on the potential neurobiological mechanisms underlying the effectiveness of metacognitive therapies.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus4WoS4OpenAlex4
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2020
    As a Neo-Pragmatist Philosopher Hans Joas Concept of Value

    Köse, Fatma Tosun

    As an important neo-pragmatist philosopher Hans Joas notes that the term of value is very controversial in academic circles. But the analysis of how values arise have failed. For this reason he refers in ‘The Genesis of Values’ to some classical philosophers in sociology and philosophy. He presents and discusses their conception of values and the genesis of values. As a result of his research he formulates his own theory of the genesis of values under the inspiration of Pragmatism: ‘Values, arise from the experiences of self formation and self-transcendence of humanbeings. But Joas doesn’t refer to transcendental existence. He uses this term as going beyond ourselves. And self- formation is a process in that individuals achieve their self-identity.

Tam Kayıt
AlanDeğerDil
dc.date.accessioned2026-10-29T17:17:51.269622174Z
dc.date.available2026-10-29T17:17:51.269622174Z
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/bayburt/10396
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleKöse, Fatma Tosun
person.affiliation.nameİlahiyat Fakültesi, Felsefe ve Din Bilimleri Bölümü, İslam Felsefesi Anabilim Dalı
person.familyNameKöse
person.givenNameFatma Tosun
person.identifier.orcid0000-0002-8978-0917
person.interestFelsefe Ve Din Bilimleri
person.interestİslam Felsefesi
person.interestDin Felsefesi
person.jobTitleDr. Öğr. Üyesi
person.name.variantTosun Köse, Fatma
person.statusverified
person.urlhttps://rdlsis.bayburt.edu.tr/tr/researcher/fatma-tosun-kose