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DETERMINATION OF ANTI-UREASE ACTIVITY OF PROPOLIS FROM MARMARA REGION OF TURKEY; [Türkiye'nin Marmara Bölgesinden Elde Edilen Bazi Propolislerin Anti-üreaz Aktivitesinin Belirlenmesi]

MakaleAçık ErişimScopus SJRQ4
  • SDG 3 · Sağlık ve Kaliteli Yaşam

Özet

Propolis is a natural product collected by honeybees from plants especially flowers and buds by mixing with wax and resin and used for many purposes in hive. It is known that propolis has been used in the treatment of various diseases in traditional medicine for many years and has biological activities such as antioxidant, antimicrobial, antiulcer, antitumor, anti-inflammatory. There is increasing interest in alternative approaches to inhibit Helicobacter pylori (H. pylori) and thereby treat many gastric diseases. This study investigated various properties of raw propolis samples from the Marmara region of Turkey. Anti-urease activity was investigated in propolis samples. The anti-urease activity of IC50 values ranged from 1.110 to 5.870 mg/mL. As a result, it can be said that propolis extract is a good inhibitor that can be used in the treatment of H. pylori to improve human health.

Anahtar Kelimeler

Enyzme inhibitionPropolisUrease
RDL Kalıcı Bağlantı (PID)
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Tam Kayıt
AlanDeğerDil
dc.contributor.authorCan, Zehra
dc.contributor.authorKara, Yakup
dc.contributor.authorKolayli, Sevgi
dc.contributor.authorÇakmak, Ibrahim
dc.date.accessioned2026-10-29T19:09:09.125889371Z
dc.date.available2026-10-29T19:09:09.125889371Z
dc.date.issued2022
dc.description.abstractPropolis is a natural product collected by honeybees from plants especially flowers and buds by mixing with wax and resin and used for many purposes in hive. It is known that propolis has been used in the treatment of various diseases in traditional medicine for many years and has biological activities such as antioxidant, antimicrobial, antiulcer, antitumor, anti-inflammatory. There is increasing interest in alternative approaches to inhibit Helicobacter pylori (H. pylori) and thereby treat many gastric diseases. This study investigated various properties of raw propolis samples from the Marmara region of Turkey. Anti-urease activity was investigated in propolis samples. The anti-urease activity of IC50 values ranged from 1.110 to 5.870 mg/mL. As a result, it can be said that propolis extract is a good inhibitor that can be used in the treatment of H. pylori to improve human health.
dc.identifier.doi10.31467/uluaricilik.1068885
dc.identifier.eissn2687-5594
dc.identifier.endpage30
dc.identifier.issn1303-0248
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85133500913
dc.identifier.startpage25
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/bayburt/12067
dc.identifier.volume22
dc.language.isoen
dc.publisherBursa Uludag University
dc.relation.ispartofUludag Aricilik Dergisi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEnyzme inhibition
dc.subjectPropolis
dc.subjectUrease
dc.titleDETERMINATION OF ANTI-UREASE ACTIVITY OF PROPOLIS FROM MARMARA REGION OF TURKEY; [Türkiye'nin Marmara Bölgesinden Elde Edilen Bazi Propolislerin Anti-üreaz Aktivitesinin Belirlenmesi]
dc.typeArticle
rdl.citation.openalex4
rdl.citation.scopus4
rdl.citation.trdizin2
rdl.oa.statusgold
rdl.oa.urlhttps://dergipark.org.tr/en/download/article-file/2235331
rdl.scopus.quartileQ4
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexTRDIZIN