Antiproliferative and apoptotic effects of diffractaic acid in A549 and AGS cancer cells

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In this study, we determined the antiproliferative and apoptotic effects of diffractaic acid by measuring the gene expression changes of topo II α, caspase-3 and p53 on A549 and AGS cancer cells. Real time PCR assay was used to measure the change folds. It was determined that concentrations of 12,5, 50 and 100μg / ml were antiproliferative and apoptotic for the A549 cancer cell line and 50μg / ml for the AGS cell line.

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https://rdlopen.rawdatalibrary.net/r/bayburt/12227Resmi atıflarda kullanılan kalıcı adres
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https://doi.org/10.1063/1.4981747Yayıncı resmi DOI adresi
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AlanDeğerDil
dc.contributor.authorKlzll, Hamit Emre
dc.contributor.authorAǧar, Güleray
dc.contributor.editorAkdemir, A.O.
dc.contributor.editorEkinci, A.
dc.contributor.editorHan, I.
dc.contributor.editorOztekin, A.
dc.contributor.editorSet, E.
dc.contributor.editorDadasoglu, F.
dc.contributor.editorKaragoz, K.
dc.date.accessioned2026-10-29T19:09:20.833936605Z
dc.date.available2026-10-29T19:09:20.833936605Z
dc.date.issued2017
dc.description.abstractIn this study, we determined the antiproliferative and apoptotic effects of diffractaic acid by measuring the gene expression changes of topo II α, caspase-3 and p53 on A549 and AGS cancer cells. Real time PCR assay was used to measure the change folds. It was determined that concentrations of 12,5, 50 and 100μg / ml were antiproliferative and apoptotic for the A549 cancer cell line and 50μg / ml for the AGS cell line.
dc.identifier.articlenumber020099
dc.identifier.doi10.1063/1.4981747
dc.identifier.isbn978-073541503-4
dc.identifier.issn0094-243X
dc.identifier.scopus2-s2.0-85019241250
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/bayburt/12227
dc.identifier.volume1833
dc.identifier.wosWOS:000405093100099
dc.language.isoen
dc.publisherAmerican Institute of Physics Inc.
dc.relation.conference2nd International Conference on Advances in Natural and Applied Sciences, ICANAS 2017
dc.relation.ispartofAIP Conference Proceedings
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subject.classificationPhysics, Applied
dc.subject.classificationPhysics, Multidisciplinary
dc.subject.classificationPhysics
dc.subject.otherANTIOXIDANT
dc.titleAntiproliferative and apoptotic effects of diffractaic acid in A549 and AGS cancer cells
dc.typeConference Object
rdl.citation.openalex2
rdl.citation.scopus2
rdl.citation.wos1
rdl.conference.date18 April 2017 through 21 April 2017
rdl.conference.placeAntalya
rdl.oa.statusclosed
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.wos.indexConference Proceedings Citation Index - Science (CPCI-S)