Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2026Scopus SJRQ2/r/bayburt/11094
  Bioinspired Sternal Implant Design for Generic Anatomical Reconstruction: An In Silico Framework for Material Selection and Biomechanical Validation

  Kutbay, Işıl; Gerdan, Zeynep; Çolak, Murat; Tabak, Yasemin; Şensoy, Abdullah Tahir

  The sternum protects the intrathoracic organs and contributes to chest wall mechanics, which makes reconstruction after tumor resection, trauma, or infection a demanding biomechanical problem. This study presents an in silico workflow for preselecting materials for sternal implants before physical prototyping. After a virtual resection, an anatomically conformal implant was designed and candidate biomaterials were screened in CES Selector using density, elastic modulus, fatigue strength, fracture toughness, toxicity, medical grade suitability, and MRI safety. A representative subset of the screened candidates was then compared by finite element modeling in terms of stress transfer and deformation. Seventeen candidates met the screening criteria. Ti-13Nb-13Zr showed an elastic modulus of about 80 GPa, and the titanium-based candidates showed deformation values of about 0.96 to 1.03 mm, whereas GF PEEK reached about 1.74 mm. The stress shielding index also showed that titanium-based materials remained on the implant-dominant side, while polymer-based materials shifted stress transfer toward bone. Taken together, the findings suggest that Ti-13Nb-13Zr offers the best overall balance for load-bearing sternal reconstruction, whereas PEEK-based systems may be more suitable within the present model for hybrid or adjunct designs. The proposed workflow can support early implant planning and guide future experimental and clinical studies.

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• MakaleAçık Erişim2024Scopus SJRQ2/r/bayburt/11893
  Foundational Engineering of Artificial Blood Vessels’ Biomechanics: The Impact of Wavy Geometric Designs

  Yilmaz, Galip

  The design of wavy structures and their mechanical implications on artificial blood vessels (ABVs) have been insufficiently studied in the existing literature. This research aims to explore the influence of various wavy geometric designs on the mechanical properties of ABVs and to establish a foundational framework for advancing and applying these designs. Computer-aided design (CAD) and finite element method (FEM) simulations, in conjunction with physical sample testing, were utilized. A geometric model incorporating concave and convex curves was developed and analyzed with a symbolic mathematical tool. Subsequently, a total of ten CAD models were subjected to increasing internal pressures using a FEM simulation to evaluate the expansion of internal areas. Additionally, physical experiments were conducted further to investigate the expansion of ABV samples under pressure. The results demonstrated that increased wave numbers significantly enhance the flexibility of ABVs. Samples with 22 waves exhibited a 45% larger area under 24 kPa pressure than those with simple circles. However, the increased number of waves also led to undesirable high-pressure gradients at elevated pressures. Furthermore, a strong correlation was observed between the experimental outcomes and the simulation results, with a notably low error margin, ranging from 19.88% to 3.84%. Incorporating wavy designs into ABVs can effectively increase both vessel flexibility and the internal area under pressure. Finally, it was found that expansion depending on the wave number can be efficiently modeled with a simple linear equation, which could be utilized in future designs.

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