Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2021Scopus SJRQ3/r/bayburt/10783
  Development of SiO2 based doped with LiF, Cr2O3, CoO4 and B2O3 glasses for gamma and fast neutron shielding

  Aygün, Bunyamin; Sakar, Erdem; Karabulut, Abdulhalik; Alim, Bunyamin; Sayyed, Mohammed, I; Singh, Vishwanath P.; Yorgun, Nergiz Yildiz; Özpolat, Ozgur Firat

  In this study, the fast neutron and gamma-ray absorption capacities of the new glasses have been investigated, which are obtained by doping CoO,CdWO4,Bi2O3, Cr2O3, ZnO, LiF,B2O3 and PbO compounds to SiO2 based glasses. GEANT4 and FLUKA Monte Carlo simulation codes have been used in the planning of the samples. The glasses were produced using a well-known melt-quenching technique. The effective neutron removal cross-sections, mean free paths, half-value layer, and transmission numbers of the fabricated glasses have been calculated through both GEANT4 and FLUKA Monte Carlo simulation codes. Experimental neutron absorbed dose measurements have been carried out. It was found that GS4 glass has the best neutron protection capacity among the produced glasses. In addition to neutron shielding properties, the gamma-ray attenuation capacities, were calculated using newly developed Phy-X/PSD software. The gamma-ray shielding properties of GS1 and GS2 are found to be equivalent to Pb-based glass.

  AtıfScopus19·WoS19·OpenAlex16

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• MakaleAçık Erişim2021Scopus SJRQ3/r/bayburt/13472
  Determination of radioprotective and genotoxic properties of sulfamide derivatives

  Aygün, Bünyamin; Alaylar, Burak; Aklncloǧlu, Akln; Allm, Bünyamin; Kocaman, Ebu Talip; Karadayl, Mehmet; Abu Al-Sayyed, Mohammed Ibrahim; Aksu, Seyma; Sakar, Erdem; Özpolat, Özgür Flrat

  Some potential drug active substances with the ability to reduce the effects of radiation on human tissues and cells were investigated. For this purpose, eight different types of sulfamide derivatives were synthesized and nuclear radiation protection parameters were determined. Neutron radiation reduction parameters such as the half-value layer effective removal cross-sections, mean free path, and the number of particles passing through the sample were determined with GEANT4 code. Additionally, the gamma radiation attenuation parameters of the materials examined were determined using Phy-X/PSD software in the energy area of 0.015-15 MeV. These parameters are the half-value layer, mass attenuation coefficient, mean free path, exposure buildup factor and effective atomic number. Neutron radiation absorption experiments were applied using an 241Am-Be fast neutron source. All results obtained for neutron radiation were compared with paraffin and water. It has been found that the ability of sulfamide derivatives to absorb these radiations is superior to reference materials. To determine whether these derivatives could have adverse effects on human health, their genotoxic potential was determined using the Ames/Salmonella bacterial reversion test. The results showed that these derivatives can be considered genotoxically safe in tests at concentrations up to 5 mM. Thus, it is suggested that the derivative materials examined in this study can be used as active substances for a drug to be made for protection against both neutron and gamma radiation.

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  AtıfScopus10·WoS9·OpenAlex11

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