Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Agar, G.(2)
- Alpsoy, L.(2)
- Ceker, S.(2)
- Kizil, H.E.(2)
- Nardemir, G.(2)
Yayınlar
- DüzeltmeAçık Erişim2015Scopus SJRQ4Erratum to: “Antagonistic effects of Satureja hortensis essential oil against AFB1, on human lymphocytes in vitro” (Cytology and Genetics, (2014), 48, (5), 327, 10.3103/S0095452715010120)
Ceker, S.; Agar, G.; Alpsoy, L.; Nardemir, G.; Kizil, H.E.
AtıfOpenAlex1
İncele - MakaleYalnız künye2014Scopus SJRQ4Antagonistic effects of Satureja hortensis essential oil against AFB, on human lymphocytes in vitro
Ceker, S.; Agar, G.; Alpsoy, L.; Nardemir, G.; Kizil, H.E.
Satureja hortensis L. (Lamiaceae) has been used as a folk remedy to treat various such as cramps, muscle pains, nausea, indigestion, diarrhea, and infectious diseases. In this study, the antagonistic effects of essential oil of S. hortensis (SHE) were studied against aflatoxin B1 (AFB1) in human lymphocytes in vitro. The analysis of the essential oil was performed by using Gas chromatography-mass spectrometry (GC-MS). Anti-genotoxic effects of the SHEs was evaluated using sister chromatid exchange (SCE), micronuclei (MN) tests against AFB1. Also level of malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities used to determine the anti-oxidative effects of the SHEs. This result showed AFB1 (5 μM) increased the frequencies of SCE, MN and the level of MDA. AFB1 at the same concentration decreased the activities of SOD and GPx. However, different concentrations of SHE with AFB1 decreased the frequency of SCE and MN and level of MDA and also increased the activities of SOD and GPx significantly. Especially, the 1.0, 1.5, 2.0 μL dose of SHE are more effective than other doses. The results of this experiment have clearly shown that SHE has strong antioxidative and antigenotoxic effects, these biological activities of SHEs can be due to its component.
AtıfScopus6WoS6OpenAlex10İncele - DergiCytology and Genetics