Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ2Bioinspired Sternal Implant Design for Generic Anatomical Reconstruction: An In Silico Framework for Material Selection and Biomechanical Validation
Kutbay, Işıl; Gerdan, Zeynep; Çolak, Murat; Tabak, Yasemin; Şensoy, Abdullah Tahir
The sternum protects the intrathoracic organs and contributes to chest wall mechanics, which makes reconstruction after tumor resection, trauma, or infection a demanding biomechanical problem. This study presents an in silico workflow for preselecting materials for sternal implants before physical prototyping. After a virtual resection, an anatomically conformal implant was designed and candidate biomaterials were screened in CES Selector using density, elastic modulus, fatigue strength, fracture toughness, toxicity, medical grade suitability, and MRI safety. A representative subset of the screened candidates was then compared by finite element modeling in terms of stress transfer and deformation. Seventeen candidates met the screening criteria. Ti-13Nb-13Zr showed an elastic modulus of about 80 GPa, and the titanium-based candidates showed deformation values of about 0.96 to 1.03 mm, whereas GF PEEK reached about 1.74 mm. The stress shielding index also showed that titanium-based materials remained on the implant-dominant side, while polymer-based materials shifted stress transfer toward bone. Taken together, the findings suggest that Ti-13Nb-13Zr offers the best overall balance for load-bearing sternal reconstruction, whereas PEEK-based systems may be more suitable within the present model for hybrid or adjunct designs. The proposed workflow can support early implant planning and guide future experimental and clinical studies.
- MakaleYalnız künye2026Scopus SJRQ2Effect of Erbium Addition to A380 Aluminum Alloy on Mechanical and Microstructural Properties
Gültekin, Çağrı; Çolak, Murat; Tabak, Yasemin; Şensoy, Abdullah Tahir
There are many studies on improving the properties of aluminum alloys, but the addition of rare earth elements occupies a particularly important place among them. In this study, the effect of erbium (Er) addition on the microstructure and mechanical properties of A380 aluminum casting alloy was systematically investigated. A series of alloys with varying Er contents (0.03%, 0.05% and 0.1 wt.%) was fabricated using the conventional casting method. The addition of Er led to significant grain refinement, primarily due to the formation of Al3Er intermetallic particles, which acted as potent nucleation sites during solidification. Optical microscopy and SEM analyses confirmed the morphological transformation of the eutectic silicon phase into a finer and more fibrous structure. Mechanical testing revealed that the alloy containing 0.1 wt.% Er exhibited the highest ultimate tensile strength (236 MPa), elongation (4.56%), and hardness (87.6 HB), indicating an optimal balance between strength and ductility. The improvement is attributed to both microstructural refinement and dispersion strengthening mechanisms. These results suggest that controlled Er addition can be an effective strategy for enhancing the performance of cast Al–Si alloys, making them promising candidates for demanding structural applications in the automotive and aerospace industries.
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İncele - Derleme MakaleAçık Erişim2026Scopus SJRQ2Titanium and polyetheretherketone for spinal fusion cages: a comparative narrative review of material behavior, structural design, and clinical translation
Hasheminasab; Bazmi, Arian; Hamsianetefagh, Rojin; Tabak, Yasemin; Ashkani, Omid; Mahboubizadeh, Shahram; Colak, Murat; Şensoy, Abdullah Tahir
Cage material selection in spinal fusion requires a trade-off among biological fixation, mechanical compatibility, subsidence resistance, and postoperative imaging. This structured narrative review compares titanium and polyetheretherketone (PEEK) cages across seven domains: osseointegration, modulus matching, endplate load transfer, surface biofunctionality, imaging, additive manufacturing and personalization, and geometry-guided architecture. Peer-reviewed literature indexed in PubMed/MEDLINE, Scopus, and Web of Science was considered from database inception through May 2026, with emphasis on comparative clinical studies, systematic reviews, meta-analyses, and mechanistic studies directly relevant to cage design. Preclinical studies favor porous and additively manufactured titanium for bone–implant integration, but a consistent fusion-rate advantage in anterior cervical discectomy and fusion (ACDF) has not been established. In lumbar surgery, lower subsidence has been reported in selected lateral lumbar interbody fusion cohorts, while results after transforaminal lumbar interbody fusion remain heterogeneous. PEEK retains advantages in radiolucency and intrinsic modulus matching, while surface-modified and porous PEEK can improve biological performance. Subsidence is not determined by chemistry alone; cage footprint, architecture, endplate preparation, fixation, and bone quality remain major modifiers. Current evidence therefore supports procedure and design-specific selection rather than universal replacement of either platform. Long-term comparative data and standardized definitions of fusion and subsidence remain limited.
