2026-10-30T01:55:01Zhttps://bayburt-rdlopen.rawdatalibrary.net/oai/requestoai:bayburt-rdlopen.rawdatalibrary.net:bayburt/139992026-10-29T19:43:50Zopenairedrivercom_bayburt_10000col_bayburt_10001Endurance training attenuates the oxidative stress due to acute exhaustive exercise in rat liverTaysi, S.Oztasan, N.Efe, H.Polat, M.F.Gumustekin, K.Siktar, E.Canakci, E.Akcay, F.Dane, S.Gul, M.Antioxidant enzymesEndurance trainingExhaustive exerciseMalondialdehydeOxidative stressThe aim of this study was to investigate whether an 8-week treadmill training attenuates exerciseinduced oxidative stress in rat liver. Male rats were divided into untrained and trained groups. Endurance training consisted of treadmill running at a speed of 2.1 km/h, 1.5 h/day, 5 days a week for 8 weeks. To see the effects of endurance training on acute exhaustive exercise induced oxidative stress, untrained and trained rats were further devided into two groups: animals killed at rest and those killed after acute exhaustive exercise, in which the rats run at 2.1 km/h (10% uphill) until exhaustion. Acute exhaustive exercise increased malondialdehyde level in untrained but not in trained rats. It decreased the activity of glutathione peroxidase and total (enzymatic plus non-enzymatic) superoxide scavenger activity in untrained rats and catalase activity in trained rats. However, it did not affect glutathione S-transferase, glutathione reductase, superoxide dismutase and non-enzymatic superoxide radical scavenger activities in both trained and untrained rats. On the other hand, endurance training decreased glutathione peroxidase and glutathione S-transferase activities. The results suggested that endurance training attenuated exercise-induced oxidative stress in liver, probably by preventing the decreases in glutathione peroxidase and total superoxide scavenger activities during exercise.2008Articlehttps://rdlopen.rawdatalibrary.net/r/bayburt/13999https://doi.org/10.1556/aphysiol.95.2008.4.21588-2683enActa Physiologica Hungaricainfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://bayburt-rdlopen.rawdatalibrary.net/tr/items/bayburt/13999